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DAFTAR ISI

Halaman Judul ......................................................................................... i


Daftar Isi .................................................................................................. ii
Daftar Gambar ......................................................................................... iii
Daftar Tabel ............................................................................................. iv
BAB I PENDAHULUAN .......................................................................... 1
BAB II TINJAUAN PUSTAKA............................................................... 3
2.1 Anatomi dan Fisiologi .................................................................... 3
2.2 Definisi Nefroblastoma .................................................................. 4
2.3 Epidemiologi Nefroblastoma .......................................................... 5
2.4 Etiologi Nefroblastoma .................................................................. 5
2.5 Patofisiologi Nefroblastoma............................................................ 6
2.6 Penyebaran dan Metastasis Nefroblastoma ..................................... 8
2.7 Gambaran Klinis Nefroblastoma..................................................... 10
2.8 Diagnosis Nefroblastoma ................................................................ 11
2.9 Penatalaksanaan Nefroblastoma...................................................... 27
2.10 Diagnosis Banding Nefroblastoma ............................................... 33
2.11 Prognosis Nefroblastoma .............................................................. 38
BAB III KESIMPULAN ........................................................................... 39

Daftar Pustaka

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DAFTAR GAMBAR

Gambar 1. Anatomi Ginjal .......................................................................... 3


Gambar 2. X-ray Thorax Normal ................................................................ 13
Gambar 3. X-Ray Thoraks Metastasis Tumor Wilms ................................. 13
Gambar 4. Foto Polos Abdomen ................................................................. 14
Gambar 5. Foto Polos Abdomen Tampak Massa dikanan .......................... 14
Gambar 6. Foto Polos Abdomen Tampak Massa Unilateral....................... 14
Gambar 7. Foto IVP Normal ....................................................................... 15
Gambar 8. Tumor Wilms Gnjal Kiri pada IVP ........................................... 16
Gambar 9. USG Abdomen Normal ............................................................. 17
Gambar 10. Gambaran Nephroblastoma ..................................................... 17
Gambar 11. USG Abdomen Potongan Aksial Terdapat Massa Ginjal Kiri 18
Gambar 12. CT Scan Abdomen Normal ..................................................... 19
Gambar 13. CT Scan Abdomen terdapat Massa pada Ginjal...................... 19
Gambar 14. CT abdomen tampak lateral pada Tumor Wilms .................... 20
Gambar 15. CT-Scan abdomen tampak tumor Wilms pada ginjal kanan ... 21
Gambar 16. CT scan tampak penebalan...................................................... 22
Gambar 17. Cavitas Metastasis ................................................................... 23
Gambar 18. MRI Abdomen Normal (dengan Kontras) .............................. 24
Gambar 19. MRI pada Tumor Wilms (dengan Kontras) ............................ 25
Gambar 20. Tumor Wilms pada Anak 3 tahun ........................................... 25
Gambar 21. Histopatologi Tumor Wilms ................................................... 27
Gambar 22. Tumpahan Tumor Intraoperatif diterapi sesuai NWTS ......... 32
Gambar 23. Pengurangan Ukuran Tumor setelah Kemoterapi SIOP ......... 33
Gambar 24. Hepatoblastoma ....................................................................... 34
Gambar 25. Karsinoma Sel renal ................................................................ 35
Gambar 26. Rhabdomysarcoma .................................................................. 36
Gambar 27. Neuroblastoma ........................................................................ 38

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DAFTAR TABEL

Tabel 1. Kelainan Kongenital dan Sindrom Terkait Tumor Wilms ............ 6


Tabel 2. Stadium Perkembangan Tumor Wilms menurut NWTS .............. 9
Tabel 3. Penyebaran Tumor Wilms Menurut TNM .................................... 9
Tabel 4. Staging Menurut NWTS dan SIOP dalam Penatalaksanaannya ... 29
Tabel 5. Manajemen Tumor Wilms sesuai NWTS ..................................... 30
Tabel 6. Manajemen Tumor Wilms sesuai SIOP ........................................ 31
Tabel 7. Regimen Terapi Pasca Operasi sesuai SIOP ................................. 31

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