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EXCOECARIA AGALLOCHA L.

Below is an extract (page 11/53 and page 48/53) from the presentation given by
Prof. Dinh xuan Ba in the BioTrade Conference held in Geneva on May 2005.
Page 11/53

Distributional range: Japan, China, Taiwan, Bangladesh, India, Sri Lanka,


Cambodia, Myanmar, Thailand, Vietnam, Malaysia, Indonesia, Papua New
Ghinea, Philippines, Australia, Fiji, New Caledonia, Niue, Tonga.
Other common names: blind-your-eyes-tree, milky mangrove, river poisontree,
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Page 48/53

Classification:

Excoecaria agallocha Linnaeus fruits

Excoecaria agallocha Linnaeus tree trunk

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Excoecaria agallocha Linn. pieces

SECOIN Corporation Applied Biotech Center


227 Dien Bien Phu street, Ward 15, Binh Thanh district, HCMc, 718512 Vietnam.
Tel: 84-8- 6255 0909; 84-4-39718899; E-mails: secoinbio@secoin.vn; dxb@secoin.vn 3
CHEMICAL CONSTITUENTS OF EXCOECARIA AGALLOCHA LINN.

Triterpenoids & triterpene alcohol:


taraxer-14-ene-3-one; taraxer-14-ene-3a-ol; taraxer14-ene-3-ol; stigmast-5-en-3-yl (6-O-
heptadecanoyl--D-glucopyranoside); taraxerone; beta-amyrin acetate; 3beta-[(2E,4E)-6-oxo-
decadienoyloxy]-olean-12-ene; acetylaleuritolic acid; cycloart-22-ene-3beta, 25-diol;

Diterpenoids:
3-oxo-ent-13epi-8(13)-epoxy-15-chloro-14-hydroxylabdane;ent-15-chloro-13,14-
dihydroxylabd-8(9)-en-3-one; ent-15-chloro-labd-8(9)ene-3,13,14-triol; ent-11-hydroxy-
8(14),15-isopimaradien-3-one; 8,13-epoxy-3-nor-2,3-seco-14-epilabden-2,4-olide; ent-3-oxo-
13-epi-manoyl oxide; ent-3-hydroxy-13-epi-manoyl oxide; (13R,14S)-ent-8,13;14,15-
diepoxy-13-epi-labdan-3-one; ent-16-hydroxy-3-oxo-13-epi-manoyl oxide; ent-15-
hydroxylabda-8(17),13E-dien-3-one; labda- 8(17),13E-diene-3,15-diol; 3,18-dihydroxy-
3,20-epoxybeyer-15-ene; (15R,16S)-ent-15,16-epoxybeyeran-3-one; ent-3-hydroxykaur-16-
en-2-one;
Steroids & others:
beta-sitostenone; (24R)-24-ethylcholesta-4,22-dien-3-one; beta-sitosterol; 14-taraxeren-3-one;
18-oleanen-3-one; 3, 28-dihydroxyl-lupeol; 28-hydroxy-20 (29)-lupen-3-one; 18-oleanen-3-ol;
dibutyl phthalate; diethylhexyl phthalate; stigmast-4-en-3-one; phaeophytin A; phaeophorbide
A;

Chemicals in latex: Exocarol; agalocol; isoagalocol; mannitol; -amyrin; 3-epimer; -


amyrenone; cycloartenol;
Chemicals in leaves, twigs, barks : Epitaraxerol; phorbol ester; flavanone glycoside;
piscicidal (which is toxic to fish);
Medicinal uses:
Bioactivity of Excoecaria agallocha. School of Biomedical Sciences, University of Ulster, Northern
Ireland, UK. Nusrat Subhan; Mohammad Ashraful Alam; Firoj Ahmed; Israt Jahan Shahid; Lutfun
Nahar; Satyajit Dey Sarker (s.sarker@ulster.ac.uk)

Anti Reverse transcriptase and anticancer activity of stem ethanol extracts of Excoecaria agallocha
(Euphorbiaceae), Ceylon Journal of Science (Bio. Sci.), 40 (2), 147155. Patil, R.C., Manohar, S.M.,
Upadhye, M.V., Katchi, V.I., Rao, A.J., Mule, A. and Moghe, A.S. (2011)

Anti-ulcer activity of Excoecaria agallocha bark on NSAID-induced gastric ulcer in Albino Rat,
Global Journal of Pharmacology, 3 (3), 123126, 2009. P. Thirunavukkarasu, L. Ramkumar and T.
Ramanathan.
SECOIN Corporation Applied Biotech Center
227 Dien Bien Phu street, Ward 15, Binh Thanh district, HCMc, 718512 Vietnam. 4
Tel: 84-8- 6255 0909; 84-4-39718899; E-mails: secoinbio@secoin.vn; dxb@secoin.vn

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