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Copyright Blackwell Munksgaard 2007

Bipolar Disorders 2007: 9: 589595 BIPOLAR DISORDERS

Original Article

Coping styles in prodromes of bipolar mania


Parikh SV, Velyvis V, Yatham L, Beaulieu S, Cervantes P, MacQueen G, Sagar V Parikha, Vytas Velyvisb,
Siotis I, Streiner D, Zaretsky A. Coping styles in prodromes of bipolar Lakshmi Yathamc, Serge Beaulieud,
mania. Pablo Cervantesd, Glenda
Bipolar Disord 2007: 9: 589595. Blackwell Munksgaard, 2007 MacQueene, Irene Siotise, David
Streinera and Ari Zaretskya
Objectives: Psychological studies have identied that dierent coping a
strategies aect outcome in bipolar disorder (BD), with the possibility of Department of Psychiatry, University of Toronto,
b
preventing mania by eective coping with prodromes. This study seeks to Centre for Addiction and Mental Health, Toronto,
examine coping mechanisms using a recently developed scale to clarify Ontario, cDepartment of Psychiatry, University of
the relationship of coping styles to clinical and demographic British Columbia, Vancouver, British Columbia,
d
characteristics, and to identify coping dierences between bipolar I and Department of Psychiatry, McGill University,
II subjects. Montreal, Quebec, eDepartment of Psychiatry,
McMaster University, Hamilton, Ontario, Canada
Methods: The Coping Inventory for Prodromes of Mania (CIPM) was
completed by 203 bipolar patients, along with other diagnostic and
clinical measures. The CIPM is organized into four factors of coping
including: stimulation reduction (SR), problem-oriented coping (PR),
seeking professional help (SPH), denial and blame (DB). CIPM
psychometric properties and its relationship to demographic and clinical
factors, dysfunctional attitudes, and mood symptoms were examined.
Coping proles were generated by BD subtype (I versus II).
Key words: bipolar disorder bipolar type II
Results: The CIPM displayed psychometric properties consistent with
cognitive behavioral therapy coping behavior
the single previous study with this instrument. Neither demographic/
insight mania psychoeducation
clinical characteristics nor mood symptoms showed any particular
relationship with the CIPM. Clear dierences in coping also emerged
Received 23 September 2005, revised and
between BD I and BD II subjects. BD I tended to use a wider range of
accepted for publication 28 September 2006
coping strategies and scored highly on the SPH factor as compared to
BD II subjects. BD II participants preferred to use DB and PR, but were Corresponding author: Sagar V. Parikh, MD,
less likely to use SPH and SR. FRCPC, Department of Psychiatry, Toronto Western
Hospital, 399 Bathurst Street, Toronto, ON, M5T
Conclusions: The CIPM appears to be a valid measure of coping. 2S8, Canada. Fax: +1 416 603 5039;
Coping style preferences appear to dier according to bipolar subtype. e-mail: sagar.parikh@uhn.on.ca

Bipolar disorder (BD) is a highly recurrent illness early warning signs and initiate adaptive coping
with current pharmacotherapy providing only responses in the prodromal stages of mania with
moderate treatment success. Intensive eorts have the aim of minimizing or preventing acute manic
been made in recent years to systematically study episodes, as well as the negative social and
psychosocial interventions, including psycho-edu- psychological sequelae of these episodes.
cation, cognitive-behavioral therapy, family ther- The systematic investigation of coping strategies
apy, and interpersonal psychotherapies. All of in the context of prodromes of mania began with a
these interventions teach patients formal symptom study by Lam and Wong (2) in which 40 bipolar I
self-monitoring, identication of early warning patients were interviewed on illness prodromes and
signs of relapse, and foster enhanced coping coping. Their study found that 93% of bipolar
techniques once serious symptoms have emerged patients could identify prodromes of mania and led
(1). Ideally, the goal of self-monitoring is to detect to the development of a self-report questionnaire,
the Coping Inventory for Prodromes of Mania
(CIPM) (3). Following classical scale develop-
The authors of this paper do not have any nancial or other rela- ment procedures, a scale of 23 items was created.
tionships that might result in a conict of interest. Using principal components analysis, the scale
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Parikh et al.

demonstrated four factors: stimulation reduction Inclusion criteria for this study were: principal
(SR), problem-directed coping (PR), seeking pro- diagnosis of BD I or II, in partial or complete
fessional help (SPH), and denial or blame (DB). remission [17-item Hamilton Depression Rating
Both SR and SPH were positively related to Scale (HDRS) < 14, Clinician Administered Rat-
improved social functioning whereas DB was neg- ing Scale for Mania (CARS-M) < 12], 1865 years
atively related to social functioning. Evaluation of of age, on a consistent dose of a mood stabilizing
coping mechanisms also proved to be predictive: an medication for at least four weeks prior to
18-month follow-up study from this same popula- enrollment, at least two mood episodes or clinically
tion showed that investigator ratings of coping signicant subsyndromal periods in the past three
responses at time 1 signicantly predicted manic years. Exclusion criteria were the following: elec-
symptom severity at time 2, 18 months later (4). troconvulsive therapy within one month of enroll-
With a valid tool to characterize coping strat- ment, severe personality disorder, active general
egies, the next step is to identify which strategies medical condition that could interfere with treat-
augur successful disease management, and how ment, current suicidality or homicidality. Subjects
these coping strategies may be inuenced by were excluded from the overall cognitive behavior-
disease or patient characteristics. Research into al therapy versus psychoeducation study if they
general coping processes suggests that the use and endorsed any severe substance abuse or depen-
timing of coping mechanisms depends both on dence in the previous three months. All subjects
individual characteristics, such as personal values were required to provide their written informed
and self-appraisal of resources to deal with stress, consent prior to participation, and institutional
as well as external factors, such as how to appraise research ethics board approval was granted.
and assess the specic attributes of the threatening
situation (5). The general purpose of the current
Procedures
study is to investigate coping with early warning
signs of mania in BD, and particularly if BD I and Recruitment was largely through self-referral from
II patients dier in their coping strategies, given information being posted in local hospitals and
that bipolar I patients endure disabling manic other advertising methods. Interested subjects
episodes. More specically, this study is designed called for information, and attended an initial
to: (i) examine normative data on the CIPM in a appointment at which point they gave written
large Canadian sample of BD patients; (ii) deter- consent to participate. The initial part of the
mine whether the CIPM is related to current mood interview obtained basic demographic and general
symptoms and dysfunctional attitudes; (iii) investi- clinical information and history, followed by a
gate whether demographic and clinical character- comprehensive diagnostic interview using a stand-
istics impact coping preferences in BD; and (iv) ardized semi-structured instrument [Structured
examine coping proles as a function of bipolar Clinical Interview for DSM-IV (SCID)] (6) to
subtype. conrm diagnostic criteria. Care was taken to
ensure inclusion criteria were met and that no
exclusionary criteria were met. Subsequently, cli-
Methods ents lled out several questionnaires and were
assessed for their current manic and depressive
Sample
symptom severity using standardized clinician-
Subjects (n 203) were obtained from four large administered rating scales.
urban sites across Canada that were involved in an
ongoing randomized controlled trial evaluating
Background information
two psychosocial treatments for BD. Both of the
psychosocial interventions given included strat- Data were collected on demographic information
egies for monitoring and coping with early warning such as age, sex, occupational status, marital
signs of mania, thus, the CIPM was used as one of status, as well as clinical information such as
the outcome measures of that study. The results estimated number of previous depressive and
described herein reect only the pre-treatment manic episodes, duration of illness, and age of
(baseline) data as many participants are still in onset.
the follow-up phase. Further information will be
obtained at the conclusion of the follow-up phase
Diagnostic information
regarding the ability of the CIPM to detect post-
treatment change and its relationship with other Diagnostic information and clinical history
variables of interest. was obtained using the SCID (6). This was
590
Coping styles in prodromes of mania

administered to all subjects by trained clinical


Statistical analyses
interviewers.
Multivariate analyses of variance was used to
screen for multivariate eects of general demo-
Coping with prodromes of mania
graphic or clinical characteristics on the four
Coping Inventory for Prodromes of Mania CIPM subscales, followed by univariate analyses
(CIPM). This 23-item scale was designed to to identify where these dierences may lie. In
assess four types of coping responses to pro- addition, to identify prole preferences for coping
dromes of mania which include stimulation reduc- strategies within bipolar subtype (I versus II), a
tion, problem directed coping, seeking professional within subjects multivariate analysis of variance
help, and denial or blame. Respondents are asked was used.
to rate the frequency with which they use each
coping strategy on a scale from 1 (never) to 4 (all
the time). The original article by Wong and Lam Results
(3) reports that all of the subscales demonstrate
Background information
good stability and internal consistency (alphas
range from 0.700.85, except for seeking profes- The current study sample was comprised of 203
sional help 0.50). bipolar I and II patients. There were 147 BD I
patients (73%) and 56 BD II patients; 118 of which
were female (58%), while 85 were male. The mean
Current mood symptoms
(SD) age for this sample was 40.8 (10.96) years
Hamilton Depression Rating Scale (HDRS- (range 1861 years). In terms of education,
17). Current depressive symptoms were assessed 16.4% had either partially completed or completed
with the 17-item HDRS (7). It is the gold-standard in high school, 17.9% had attended post-secondary
clinician-administered rating scales for depression. specialized training or college, 17.9% had attended
It contains 17 items that are rated by an interviewer university, 34.3% had completed a university
for the past week. It has been shown to be a valid and degree, 12% either nished or had received post-
reliable measure of depressive symptom severity in graduate education. In the sample, 52.7% were not
numerous studies and is sensitive to change over currently working at the time of recruitment,
time. The point spread of items range between 04 or however, only 18% considered themselves as fully
02 (0 none; 4/2 severe). unemployed; 34.5% were being at least partially
subsidized through welfare or disability payments,
Clinician Administered Rating Scale for Mania while a further 14.2% were being supported by
(CARS-M). Manic symptom severity was their spouses or family members.
assessed using the CARS-M (8). It is a 15-item
semi-structured interview and rating scale that
Symptom measures
assesses symptoms of mania over the last seven
days and is comprised of two facets: mania (10 The means (SD) for all of the measures used in this
items) and psychosis (5 items). The current study study are provided in Table 1.
used only the mania factor in all statistical Both current depressive symptom (HDRS-17)
analyses. Most of the items on the scale reect severity scores [mean (SD) 6.82 (4.94)] as well as
DSM-IV criteria for mania. All items are rated current manic symptom (CARS-M) severity scores
on a 6-point scale based on increasing severity [mean (SD) 1.79 (2.92)] are indicative of symp-
(05). This scale has been normed on a large toms that are consistent with remission status
sample and has demonstrated high correlations according to published interpretive guidelines. The
with Young Mania Rating Scale scores (r mean (SD) DAS score for this sample was 134.10
0.94). (35.86). Scores in this range are slightly higher than
those previously found in a remitted unipolar
Dysfunctional Attitudes Scale (DAS). The DAS is depressed sample; however, they are consistent
a 40-item self-report instrument, designed to iden- with remission status for bipolar patients (10).
tify cognitive distortions related to depression (9).
All items are scored on a 7-point scale where higher
Coping style measure (CIPM)
scores reect more maladaptive beliefs. The DAS
reports very good internal consistency (alpha The means (SD) for all CIPM subscale scores
ranges from 0.840.92) and excellent testretest are also presented in Table 1 and are similar to
reliability (8-week 0.800.84). those of Wong and Lam (3). Except for the
591
Parikh et al.

Table 1. Total sample mean, SD, and internal consistencies for main tionship between stimulation reduction and denial
measures or blame subscales. Moreover, all of the adaptive
Scales (n 203) Mean SD Alpha coping subscales were positively intercorrelated,
while the one negative factor (denial and blame)
HDRS-17 6.82 4.94 0.739 was negatively correlated with all of the other
CARS-M 1.79 2.92 0.786
DAS 134.03 35.88 0.934
subscales of the CIPM as might be expected.
CIPM-SR 1.96 (1.97) 0.58 (0.70) 0.585 (0.77)
CIPM-PR 2.15 (2.22) 0.59 (0.72) 0.804 (0.85)
CIPM-SPH 2.17 (2.27) 0.86 (0.83) 0.626 (0.53)
CIPM multivariate analyses
CIPM-DB 2.16 (2.21) 0.52 (0.54) 0.712 (0.72) A multivariate analysis of variance (MANOVA)
Parentheses indicate comparative data from Wong and Lam (3).
was performed for demographic and clinical var-
HDRS-17 17-item Hamilton Depression Rating Scale; CARS- iables on the CIPM subscales. The multivariate
M Clinician Administered Rating Scale for Mania; DAS analysis was performed on the four CIPM sub-
Dysfunctional Attitudes Scale; CIPM-SR Coping Inventory for scales using four demographic variables which
Prodromes of Mania-Stimulation Reduction; CIPM-PR Coping included sex, marital status, occupation category,
Inventory for Prodromes of Mania-Problem-directed Coping;
CIPM-SPH Coping Inventory for Prodromes of Mania-Seeking
and age. The MANOVA analysis found no signif-
Professional Help; CIPM-DB Coping Inventory for Prodromes icant main eects for any of the demographic
of Mania-Denial or Blame. variables tested.
The second multivariate analysis examined main
stimulation-reduction subscale, the remainder of eects for clinical characteristics of BD including
the CIPM subscale internal consistencies ranged bipolar subtype (I versus II), duration of illness,
between 0.630.80. The average Cronbachs alpha age of onset, and number of previous depressive,
reliability in our sample was slightly lower than manic, and hypomanic episodes on the four CIPM
that of the original study by Wong and Lam (0.68 factors. A signicant multivariate main eect was
and 0.72 respectively). Furthermore, our study found for bipolar subtype [F(4,123) 3.49, p
found two factors with inadequate reliability lev- 0.01]. Univariate ANOVA results showed that the
els (CIPM-SR and CIPM-SPH <0.70), whereas eect for bipolar subtype was evidenced only on
Wong and Lam only had one factor below this the CIPM seeking professional help factor
threshold (CIPM-SPH). [F(1,133) 13.15, p < 0.001]. No other signi-
Intercorrelations among the CIPM subscales as cant univariate eects of BD subtype were found
well as with symptom scales and DAS measures are for any other CIPM factor.
presented in Table 2.
None of the CIPM subscales was found to be
BD I and II CIPM profiles
related to either current depressive or mania
symptoms. All but the stimulation reduction factor The means (SD) for the CIPM subscales for both
of the CIPM were related to dysfunctional atti- BD I and II subjects are presented in Table 3. Due
tudes. Furthermore, the subscales all were related to the signicant multivariate eect of BD subtype,
to the DAS in theoretically predictable ways (i.e., a more detailed analysis should identify signicant
only the denial and blame subscale was positively dierences among the four CIPM coping strategies
associated with the DAS). separately for bipolar I and II subjects.
Intercorrelations among the CIPM subscales all Thus, two within subjects MANOVAs were
were signicant except for a non-signicant rela- performed for BD I and II groups separately

Table 2. Total sample zero-order intercorrelations

CIPM scales HDRS-17 CARS-M DAS CIPM-PR CIPM-SPH CIPM-DB

CIPM-SR )0.096 )0.002 )0.125 0.630** (0.51**) 0.422** (0.44**) )0.130 ()0.05)
CIPM-PR )0.111 0.093 )0.164* 0.360** (0.48**) )0.189* ()0.02)
CIPM-SPH )0.130 )0.028 )0.216** )0.154* (0.06)
CIPM-DB 0.049 0.088 0.355**

Parentheses indicate comparative data from Wong and Lam (3).


HDRS-17 17-item Hamilton Depression Rating Scale; CARS-M Clinician Administered Rating Scale for Mania; DAS Dysfunc-
tional Attitudes Scale; CIPM Coping Inventory for Prodromes of Mania; CIPM-SR Coping Inventory for Prodromes of Mania-Stim-
ulation Reduction; CIPM-PR Coping Inventory for Prodromes of Mania-Problem-directed Coping; CIPM-SPH Coping Inventory for
Prodromes of Mania-Seeking Professional Help; CIPM-DB Coping Inventory for Prodromes of Mania-Denial or Blame.
*p < 0.01; **p < 0.001.

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Coping styles in prodromes of mania

Table 3. Coping Inventory for Prodromes of Mania subscale means and SD by bipolar subtype I versus II

CIPMSR, mean (SD) CIPMPR, mean (SD) CIPMSPH, mean (SD) CIPMDB, mean (SD)

Bipolar I 1.9898 (0.5994) 2.1882 (0.5929) 2.3152 (0.8411) 2.1424 (0.5251)


Bipolar II 1.8691 (0.5153) 2.0602 (0.5839) 1.7576 (0.7723) 2.2159 (0.4962)

CIPM-SR Coping Inventory for Prodromes of Mania-Stimulation Reduction; CIPM-PR Coping Inventory for Prodromes of Mania-
Problem-directed Coping; CIPM-SPH Coping Inventory for Prodromes of Mania-Seeking Professional Help; CIPM-DB Coping
Inventory for Prodromes of Mania-Denial or Blame.

which would allow examination of the relative Table 5. Post hoc comparisons for Coping Inventory for Prodromes of
Mania (CIPM) subscales within bipolar II group
preferences or proles of coping strategies
employed for prodromes of mania. Signicant SPH SR PR DB
within subjects multivariate eects were found for
BD I subjects [F(3,144) 12.30, p < 0.001] as Means 1.76 1.87 2.06* 2.22*
well as for BD II subjects [F(3,52) 8.37, SPH 1.76 0.11 0.30 0.46
p < 0.001], indicating that at least one CIPM SR 1.87 0.19 0.35
subscale was signicantly dierent from at least PR 2.06 0.16
one other CIPM subscale for both BD I and II DB 2.22
patients. Examination of the post hoc pairwise Note: CIPM subscale means presented in ascending numerical
comparisons for BD I subjects reveals that the order; numbers within cells refer to mean differences from lowest
most preferred coping strategy is to seek profes- mean score (i.e., higher mean score indicates that it is used
sional help followed by problem directed coping. more often). Those subscales marked with an asterisk (*) indi-
These pairwise comparisons for BD I are presented cate that they are significantly different from any subscales
which do not have an asterisk. (i.e., PR and DB are both sig-
in Table 4. nificantly different from SPH & SR; PR & DB do not differ
BD I patients are also likely to use a wider variety significantly from each other).
of coping strategies as inferred by the fact that all of SPH Seeking Professional Help; SR Stimulation Reduction;
the means of the CIPM subscales are at or above 2. PR Problem-directed Coping; DB Denial or Blame.
Examination of the post hoc pairwise comparisons
for BD II subjects shows that the most preferred
coping strategy for prodromes of mania is denial
and blame, while the least preferred coping strat- in response to manic prodromes for BD II subjects
egies are to seek professional help or to use as compared to BD I.
stimulation reduction techniques. These pairwise
comparisons for BD II are presented in Table 5.
Discussion
Only two of the subscale means were above 2,
indicating a smaller repertoire of coping strategies In an era where many psychosocial interventions
for bipolar disorder are being tested, it is critical to
have some understanding of the mechanisms of
Table 4. Post hoc comparisons for Coping Inventory for Prodromes of action. Enhanced coping styles are a common
Mania (CIPM) subscales within bipolar I group
feature of all major interventions, but have not
SR DB PR SPH been evaluated in a rigorous way. Wong and Lams
development of the CIPM provides a tool to
Means 1.99 2.14* 2.19* 2.32*
systematically characterize coping methods and
SR 1.99 0.15 0.20 0.33 allows clarication of the factors which inuence
DB 2.14 0.05 0.18 coping. Our current study substantially advances
PR 2.19 0.13 the understanding of psychosocial interventions by
SPH 2.32 providing the rst replication of the validity of the
Note: CIPM subscale means presented in ascending numerical
CIPM and by clarifying that neither demographic
order; numbers within cells refer to mean differences from lowest nor general illness characteristics are correlated to
mean score (i.e., higher mean score indicates that it is used coping styles. Furthermore, our study demon-
more often). Those subscales marked with an asterisk (*) strates that bipolar I and bipolar II subjects dier
indicate that they are significantly different from any subscales in coping mechanisms to the prodromes of mania/
which do not have an asterisk. (i.e., DB, PR & SPH do not differ
from each other but are all significantly different from SR).
hypomania. Bipolar I subjects rely more on seeking
SR Stimulation Reduction; DB Denial or Blame; PR professional help and stimulus reduction, while
Problem-directed Coping; SPH Seeking Professional Help. bipolar II subjects rely more on denial and blame.
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Parikh et al.

In terms of psychometric properties, the means and the DAS bode well for the construct validity of
and SD of the scale in our study are similar to this measure.
those reported in Wong and Lams original article, The primary purpose of this study was to
while Cronbachs alpha reliability statistics were determine whether demographic and/or clinical
slightly lower but still acceptable. Consequently, variables inuenced the use of coping strategies for
the results obtained using the CIPM-SR and prodromes of mania as measured by the CIPM in a
CIPM-SPH factors should be interpreted with sample of 203 BD patients in full or partial
some degree of caution. Nonetheless, the ndings remission. To our knowledge, this is the rst study
of this replication are strongly encouraging with to have examined coping strategies in BD as a
respect to the validity of the CIPM, given that the function of demographic and clinical characteris-
validation employed a large sample drawn from tics of BD. We found that of all of the demo-
four distinct Canadian centres as opposed to the graphic and clinical variables examined, only
original single centre European sample. bipolar subtype signicantly predicted dierences
Prodromal coping strategies were not related to in the use of coping strategies.
current mood symptoms. This nding is not Of all the clinical variables examined including
necessarily surprising given that the majority of age of onset, duration of illness, number of
the subjects in the study were in remission from previous mood episodes, and bipolar subtype,
their symptoms as a necessary condition of their multivariate analysis found only bipolar subtype
participation. The lack of signicant associations to predict dierential coping response to pro-
between the CIPM and symptom ratings of dromes of mania. Given that bipolar II patients
depression (HDRS) and mania (CARS-M) might experience only hypomania, while bipolar I
therefore be an artifact of mood symptom oor patients may experience hypomania but must have
eects. Another possibility is that patients retro- experienced mania which is dened as being more
spective perceptions of coping with past manic disabling, we would expect some dierences in
prodromes might not actually be inuenced by coping responses. Subjects with BD I were signif-
their mood symptoms. While the present study icantly more likely to seek professional help at the
cannot contribute further to the interpretation of rst signs of mania, whereas for BD II subjects,
this nding, the distinction between these two seeking professional help was the last choice. These
possible interpretations would be important in results would seem to be in keeping with coping
determining whether the CIPM should be seen as a theories as described by Folkman and Lazarus (5).
stable trait measure of coping as opposed to being Those authors dened coping as consisting of both
state-dependent. Lam and Wong (2) originally cognitive and behavioral eorts to manage specic
hoped that the CIPM could be sensitive to change external or internal demands that are appraised as
over time and with treatment; however, the ques- taxing or exceeding the persons current resources.
tion of whether this measure shows this type of Choosing a specic coping strategy is greatly
sensitivity must still be evaluated prospectively inuenced by how the stress is appraised in terms
over time as opposed to using cross-sectional of the nature of the danger, its duration, ambigu-
designs. ity, and imminence, as well as by how ones own
Correlational analyses between the CIPM sub- coping resources are evaluated by the individual.
scales and the DAS served as a validity check for In keeping with this general theory of coping, BD I
the CIPM. We expected that adaptive coping patients may seek professional help more often
strategies (i.e., stimulation reduction, problem than BD II subjects because manic episodes
directed coping, and seeking professional help) generally are more severe, imminent and unambig-
would be negatively related to the DAS whereas uous as compared to hypomanic episodes. Seeking
the denial and blame factor would be positively the assistance of a specialized professional may be
associated with the DAS. The rationale for these thought of as an eective coping strategy for any
predictions was that dysfunctional attitudes about severe condition such as mania. Conversely, hypo-
the self, the world, and ones future are likely manic episodes may be experienced as pleasurable
important determinants for how to cope in the face or as a relief from depressions. Thus BD II subjects
of stress. Examination of the correlations were all may appraise the stress of hypomania as neither
generally in line with these predictions except for threatening nor consequential, and therefore dis-
the stimulation reduction factor of the CIPM which avow more drastic coping strategies. Relatively
showed a non-signicant trend in the predicted lower scores on stimulation reduction and seeking
direction, likely explained by the poor internal professional help may be understandable then with
reliability of this factor. Overall, such consistent a BD II sub-population. The higher scores on the
predictable correlations between the CIPM factors denial or blame factor for BD II subjects suggest
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Coping styles in prodromes of mania

that it is the most popular coping strategy for rst, that the CIPM may be used as a useful and
hypomanic prodromes; however, it is also clear valid measure of the coping styles of patients;
that the use of denial or blame may indicate a lack second, that dierent interventions may alter
of insight. Studies have suggested that poor insight coping styles dierentially, providing evidence of
is related to poor management of the disorder (11) possible mechanisms of action; and nally, that
and may also contribute to the worsening of the bipolar II subjects may need modications of
condition over time. Gaining insight into ones psychosocial interventions to reect a dierent
illness and coping with prodromes is a central pattern of coping styles compared to bipolar I
concern for most psychosocial interventions for patients.
BD. These novel ndings of dierences in preferred
coping strategies between bipolar I and II argue for
Acknowledgements
further exploration in terms of etiology and clinical
implications. This study has been funded in part by the Canadian Institutes
Our study has several important limitations. We of Health Research and the Stanley Medical Research
Institute.
have used the CIPM for both bipolar I and II
subjects and found dierences, while it was not
explicitly created with bipolar II subjects in mind. References
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emerging psychosocial interventions are threefold:

595

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