Professional Documents
Culture Documents
Diabetes
28%
52%
Hypertensi
20%
on
2% 4%
survivors of patients
Surviv
ed
Non-survived (n=
Variables (n=18) 32) p value
Age in years (mean SD) 51.0619.59 46.8415.77 0.411
Fever (no, %) 18, 100.0 % 32, 100.0 % 1.000
Headache (no, %) 2, 11.1 % 2, 6.2 % 0.612
Cough (no, %) 5, 27.8 % 8, 25.0 % 1.000
Breathlessness (no, %) 7, 38.9 % 9, 28.1 % 0.532
Altered Sensorium (no, %) 1, 5.6 % 1, 3.1 % 1.000
Vomiting (no, %) 4, 22.2 % 8, 25.0 % 1.000
Jaundice (no, %) 2, 11.1 % 2, 6.2 % 0.612
Oliguria (no, %) 4, 22.2 % 12, 37.5 % 1.000
Abdominal Pain (no, %) 5, 27.8 % 12, 37.5 % 1.000
Chest pain (no, %) 2, 11.1 % 3, 9.3 % 1.000
Loose stools (no, %) 2, 11.1 % 3, 9.3 % 1.000
Temperature (mean SD) 102.481.06 102.611.01 0.658
Pulse rate (mean SD) 123.4413.51 117.635.04 0.033*
GCS 10.065.57 14.191.99 <0.001*
Respiratory rate (mean SD) 27.225.54 26.55.47 0.658
APACHE II score DAY1 23.289.65 18.757.34 0.068
Ventilator support (no, %) 16(88.9%) 14(43.8%) 0.002*
Inotropic support (no, %) 13(72.2%) 15(46.9%) 0.083
Dialysis (no, %) 2(11.1%) 8(25.0%) 0.295
Duration of ICU stay (no, %) 3.723.08 3.752.02 0.969
SOFA score was significantly low especially on day 3 (6.842.96) in survivor group as
compared to non survivor group whose mean day 3 value being (13.424.060) (Table 3).
Polymicrobial 1 (5.2%) -
Others - 1(5.2%)
Table 4 shows that Gram negative bacteria females in this cohort and mean age of
were found to be the predominant 48.3years. Similar study in India have also
pathogens associated with sepsis(73.4%). shown male preponderance with most
The most common organism responsible patients in the fourth to fifth decade.4
for sepsis was Klebsiella (36.8%), All patients had fever with breathlessness
followed by Pseudomonas (26.3%), Staph and oliguria being the next predominant
aureas and E. coli(10.5%) both. However, symptom observed in 32% patients each.
Pseudomonas was the most common Among the several disorders encountered in
organism isolated from blood culture sepsis, acute kidney injury (AKI) mostly
followed by Klebsiella. manifested clinically by decreased urine
output, is one of the most important because
Discussion it is a life-threatening condition, increases
The clinical profile of 50 patients with the complexity and cost of care, and is an
sepsis was studied with 28 males and 22 independent risk factor for mortality. 5,6 .