Name:__________________________________________

BiologyI:Unit2(ADNAMasteryUnit)Worksheet1:DNAStructure
1.WhatdothelettersDNAstandfor?

___________________________________________________

2.Twoscientistsaregivencreditfordiscoveringthestructure
ofDNA.Whatisthenameofthosetwoscientists.

a. _______________________________

b. _______________________________

3.DNAisapolymer,whichmeansthatismadeupofmany
repeatingsingleunits(monomers).Whatarethemonomers
called?

___________________________________________________

4.ThebackboneoftheDNAmoleculeismadeupoftwo
components,whatarethese?

c. _______________________________

d. _______________________________

5.Therearefourdifferentvariationsofthesemonomers(fourdifferentbases),whatarethenamesof
thosebases?

a. _______________________________

b. _______________________________

c. _______________________________

d. _______________________________

6.Thesebasesareoftwodifferenttypesofmolecules:purinesandpyrimides.Purineshave
_______________________ring(s)intheirstructure,andpyrimidineshave_______________________ring(s)intheir
structure.

7.Thetwobasesthatarepurinesare:

a. _______________________________

b. _______________________________

8.Thetwobasesthatarepyrimidinesare:

a. _______________________________

b. _______________________________
9.ChargoffsrulestatesthattheDNAofanyspeciescontainsequalamountsof_______________________and
_______________________andalsoequalamountsof_______________________and_______________________.

10.Basedonthisinformation,scientistcouldpredictthatthebase_______________________pairswith
_______________________andthebase_______________________pairswith_______________________intheformationof
theDNAmolecule.

Thisiscalledcomplementarybasepairs.ThusonestrandofDNAiscomplementarytotheother
strand(opposite/matching).

11.Thebasesarepairedby_______________________bondsalongtheaxisofthemolecule.

12.WilkinsandFranklinstudiedthestructureofDNAusing_______________________,atechniquetoexamine
molecules,andhelpedWatsonandCrickdeterminedthattheshapeofthemoleculewasa
______________________________________________.

13.Drawthebasicstructureofanucleotidewithitsthreeparts.

14.WritethecomplementarysequencetofollowingDNAstrand:

A A T T C G C C G G T A T T A G A C G T T
| ||||||||||||||||||||

15. Usetheimageattherighttocompletethefollow:

Circleanucleotide.
Labelthesugarandphosphate.
Labelthebasesthatarenotalreadylabeled