Histology slides 4.

Dense Irregular CT
o mesh of collagen fibers,
1. Mesenchyme Cells
interwoven
- ECM, FIBERS (interlacing fibers)

2. Loose connective tissue

- Fibroblast
- 2 fibers (collagen, elastic)
5. Elastic Tissue
- Adipocytes
o Elastic fibers: parallel in
- Mesentery
appearance
o Fibroblast more abundant
o Ligmentum Nuchae

3. Dense Regular CT
- Collagen: parallel
- Fibroblast: Linearly arrange 6. Reticular Tissue
- Tendon o Reticular fibers: black staining
o Lymph nodes
 7. Adipose Tissue
- 90% Adipocytes
- Chicken wire filled with fat

SPECIALIZED CONNECTIVE TISSUE

8. CARTILAGE
2 types of cartilage growth
o Derived from mesenchyme o Interstitial growth
o Composition
During embryonic
ECM (glycosaminoglycans)
development
Chrondrocytes
Division of chondroblast,
Lacunae
formation of matrix and
Filled with GAGS the maturity of matrix
Surrounded by
territorial matrix
and in between
interteritorial
matrix o Apposital growth
o PARTS
Perichondrium (fibrous
layer)
Outer layer filled
with Dense regular
tissue
Chondrogenic layer
Where
chrondrocytes is
located
Chondrocytes
Lacunae
Matrix
Hyaline Cartilage

- TRACHEA
- Outermost layer: Perichondrium
Elastic Cartilage
o 2 layers : Outer fibrous and inner
chondrogenic layer (flat elliptical - Same structure
cells- chondroblast) - But with ELASTIC FIBERS in MATRIX
nd
- 2 layer: ECM with developing - Filled also with collagen fiber
chondroblast into chondrocytes - Larger chondrocytes
o Chondrocytes filled with matrixes
in lacunae
o Lacunae: spaces which
chondrocyte is located (spaces=
matrixes)

-
Fibrocartilage

o Intervertebral disk
o NO PERICHONDRIUM
o COLLAGEN FIBERS IN MATRIX
 o Cannaliculi

BONE BONE GROWTH

- INTERMEMBRENOUS
- Protection, stability support and storage
o Not passing through the cartilage
of marrow and calcium
stage
- Development of the bone:
o Some flat bones
o Osteoblast- bone formation
o Osteoclast- bone recycling and
reabsorption
o Osteocytes- mature bone cell
- Outer layer: periosteum
- Inner layer: endosteum- where
osteoprogenitor cells located

o Compose of
Decalcified bone Traberculae- callous or
spongy part
- Structure Lacunae with osteocytes
o Lacunae - ENDOCHONDRAL
o Lamella o Passing through the cartilage stage
o Harvesian system o Epiphysal cartilage = zones of
Harvesian canal development
Volkmanns Canal Zone of Reserve cartilage
 Zone of proliferation o Biconcave disk and enucleated-
Zone of Maturity increase the surface area just to
Zone of Hyperothropy deliver oxygen to the body
Zone of Ossification

Lymphocytes

Immunological protection
2 types
Granulocytes- w/
specific specialized
granules
Agranulocytes-
w/out granules

Granulocytes

Neutrophils
2-3 lobed nuclei, w/
chromatin thread
Clear cytoplasm and
granules

o Eosinophil
o 2 lobed
nuclei
BLOOD o w/ purple
granules
- Support, transport nutrients, hormones, o Basophil
gases, waste products. Balance pH acid- o Masked
base etc. And movement of white blood nuclei
cells o Dark
- Erythrocytes and Lymphocytes stained
Erythrocytes purple
granules
Lymphocyte

- Non granulated
- Thin rim of cytoplasm and
large nucleus

o Monocyte
Larger than iother
lymphocyte
Kidney shaped
nucleus
Platelets
Clotting shits
Small dots of
purple