Professional Documents
Culture Documents
Patterson et al.
Brain CT for Atraumatic Headache and 30-Day ED Revisits
Downloaded from www.ajronline.org by 114.121.237.109 on 01/04/17 from IP address 114.121.237.109. Copyright ARRS. For personal use only; all rights reserved
OBJECTIVE. The purpose of this article is to describe the association between initial CT
for atraumatic headache and repeat emergency department (ED) visitation within 30 days of
ED discharge.
MATERIALS AND METHODS. A retrospective observational study was performed
at an academic urban ED with more than 85,000 annual visits. All adult patients with a chief
complaint of headache from January through December 2010 who were discharged after ED
evaluation were included in the analysis. Patients were excluded if they were transferred, died
in the ED, or had a diagnosis indicating a traumatic mechanism. A propensity scorematched
logistic regression model was used to determine whether the use of brain CT was associated
with the primary outcome of ED revisitation within 30 days, controlling for potential confounding variables.
RESULTS. Of 80,619 total patient visits to the ED during the study period, 922 ED discharges with a chief complaint of headache were included. A total of 139 (15.1%) patients revisited within 30 days. The return rate was 11.2% among patients who underwent CT at their
initial visit and 21.1% among those who did not. In the adjusted analysis, controlling for age,
race, sex, insurance status, triage vital signs, laboratory values, and triage pain level, the odds
ratio for revisitation given CT performance was 0.49 (95% CI, 0.270.86).
CONCLUSION. After adjustment for clinical factors, we found that patients who underwent a brain CT examination for atraumatic headache at an initial ED visit were less likely to
return to the ED within 30 days. Future appropriate use quality metrics regarding ED imaging use may need to incorporate downstream health care use.
DOI:10.2214/AJR.16.16330
Received February 16, 2016; accepted after revision
April 27, 2016.
P. S. Pang is a consultant for Janssen, Medtronic, Novartis,
Trevena, scPharmaceuticals, Cardioxyl, Roche
Diagnostics, and Relypsa and has received honoraria from
Palatin Technologies and research support from Roche and
Novartis. A. K. Venkatesh works under contract with the
Centers for Medicare & Medicaid Services to develop
hospital outcome and efficiency measures related to the
use of medical imaging and also works under contract with
the Centers for Medicare & Medicaid Innovation to lead a
national quality collaborative regarding imaging use in the
emergency department.
Based on a presentation at the Society for Academic
Emergency Medicine 2013 annual meeting, Dallas, TX.
WEB
This is a web exclusive article.
AJR 2016; 207:W117W124
0361803X/16/2076W117
American Roentgen Ray Society
1BerbeeWalsh Department of Emergency Medicine, University of WisconsinMadison School of Medicine and Public
Health, 800 University Bay Dr, Ste 310, Mail Code 9123, Madison, WI 53705. Address correspondence to B. Patterson
(bpatter@medicine.wisc.edu).
2 Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN.
3 Department of Emergency Medicine, Northwestern University, Chicago, IL.
4 Department of Biostatistics and Medical Informatics, Department of Pediatrics, University of Wisconsin School of
Medicine and Public Health, Madison, WI.
5 Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
6 Department of Emergency Medicine and Center for Outcomes Research and Evaluation, Yale University School of
Medicine, New Haven, CT.
Patterson et al.
Downloaded from www.ajronline.org by 114.121.237.109 on 01/04/17 from IP address 114.121.237.109. Copyright ARRS. For personal use only; all rights reserved
Died Within
30 Days
0 (0.0%)
Analyzed Discharges
922
No CT Performed
360
30-Day Revisit
76 (21.1%)
No Revisit
284 (78.9%)
CT Performed
562
30-Day Revisit
63 (11.2%)
No Revisit
499 (88.8%)
Unmatched
Comparison
30-Day Revisit
37 (10.3%)
No Revisit
323 (89.7%)
Matched
Comparison
W118
downstream health care use by patients. Specifically, we hypothesized that initial use of
CT for atraumatic headache would be associated with a lower likelihood of ED revisitation
and potentially reveal the inherent tradeoffs
between distinct measures of resource use.
Prior studies investigating ED returns
have been limited to administrative claims
data and therefore largely sought to identify demographic factors associated with revisits, including advanced age [10] and lack
of access to primary care [11]. Although
these analyses reveal important disparities
in access to care, they do not identify easily modifiable factors or describe the specific
relationship between emergency care interventions and ED revisitation.
Examining the relationship between index CT (i.e., CT at the first ED visit) and
subsequent health care use, defined as ED
revisits, will better inform providers seeking to better manage acute care resources
for a population of patients and policy makers developing quality measures that seek
to reduce exposure to ionizing radiation
and reduce health care costs. A better understanding of this relationship would help
identify outcomes of importance as well as
potential targets for quality improvement efforts. Although administrative claims databases are limited in their ability to evaluate
this relationship, data created by an electronic health record (EHR) can provide additional information on clinical variables
Age
Downloaded from www.ajronline.org by 114.121.237.109 on 01/04/17 from IP address 114.121.237.109. Copyright ARRS. For personal use only; all rights reserved
Male Sex
Black Race
Other Race
Private Insurance
Medicaid Insurance
Medicare Insurance
Sodium Low (< 134 mEq/L)
Sodium High (> 142 mEq/L)
Sodium Not Evaluated
Low Glucose
WBC Low
WBC High
WBC Not Evaluated
Low Hemoglobin
High Platelets
Triage Pulse Oximetry Not Recorded
Heart Rate > 100 beats/min
Heart Rate Not Recorded
Temperature > 100.4F
Temperature Not Recorded
Hypertensive
Blood Pressure Not Recorded
Triage Pain Score
(Each additional 1/10)
CT Brain Performed
Unmatched OR
1
Matched OR
relevant to an initial ED visit: chief complaints, vital signs, and use of specific laboratory and imaging tests [12, 13]. Showing
the feasibility and benefit of using clinically enriched data to evaluate ED imaging use
will also inform future efforts seeking to
use health care information technology for
the measurement of health system efficiency. We have performed a prior retrospective
study that identified an association between
the use of abdominal CT and lower 30-day
revisit rates [14]. This study uses a propensity score analysis to evaluate a similar association among a different population within the same dataset and builds on the prior
work examining the effects of imaging use
in the ED on revisit rates.
Selection of Participants
Downloaded from www.ajronline.org by 114.121.237.109 on 01/04/17 from IP address 114.121.237.109. Copyright ARRS. For personal use only; all rights reserved
Patterson et al.
No patients meeting these inclusion and exclusion criteria died in the ED, precluding enrollment. The chief complaint was chosen to capture
patients defined by their presentation, evaluation,
and management, as opposed to their final diagnosis. Discharge diagnoses were not included in the
dataset because these have poor concordance with
ED patients reason for visit or their need for admission or further advanced care [15].
Outcomes
The primary measured outcome was return visit to the ED for any reason within 30 days of initial
ED visit for atraumatic headache.
Analysis
W120
Results
Characteristics of Study Subjects
Figure 1 graphically depicts patient flow
within the study. Table 1 describes the collected demographic variables for the study
group. Overall, compared with the patients
who did not undergo CT, those who did undergo imaging at the initial ED visit were
more likely to be older, have Medicare or private insurance, and have laboratory tests per-
Age (y)
CT Imaging Performed
CT Imaging Not
Performed (n = 360)
Unmatched (n = 562)
Matched (n = 360)
39.0 (37.440.5)
42.5 (41.243.7)
45.9 (44.347.5)
Sex
Female
70.8 (65.975.3)
71.0 (67.174.6)
71.7 (66.876.0)
Male
29.2 (24.734.1)
29.0 (25.432.9)
28.3 (23.933.2)
White
42.5 (37.547.8)
48.4 (44.252.5)
49.3 (44.154.5)
Black
45.9 (40.851.1)
35.1 (31.339.2)
35.0 (30.240.1)
Other
11.5 (8.615.3)
16.5 (13.619.8)
15.7 (12.319.9)
18.1 (14.422.4)
14.9 (12.218.1)
14.2 (10.918.2)
8.3 (2.911.7)
11.7 (9.314.7)
14.4 (11.218.5)
Race
Insurance status
Self-pay or uninsured
Medicare
Medicaid
19.4 (15.723.9)
12.1 (9.615.1)
8.9 (6.312.3)
Private or other
54.2 (49.059.3)
61.2 (57.165.2)
62.5 (57.467.4)
83.6 (79.487.1)
88.1 (85.190.5)
91.7 (88.394.1)
No observations
0.05 (0.011.6)
0.8 (0.32.6)
15.0 (11.719.1)
10.9 (8.513.7)
7.2 (5.010.4)
1.4 (0.63.3)
0.5 (0.21.6)
0.3 (0.02.0)
93.6 (90.695.7)
89.9 (87.192.1)
87.8 (84.090.8)
Not recorded
Triage blood pressure
Normotensive
Hypotensive (systolic blood pressure < 80 mm Hg)
Hypertensive (systolic blood pressure > 180 or diastolic blood pressure > 100 mm Hg)
4.7 (3.07.5)
9.3 (7.111.9)
11.4 (8.515.1)
Not recorded
1.7 (0.73.7)
0.9 (0.42.1)
0.8 (0.32.6)
Triage temperature
Normal (< 100.4F [38C])
93.0 (89.995.3)
96.6 (94.897.8)
93.1 (89.995.3)
3.6 (2.16.1)
1.8 (1.03.3)
No observations
Not recorded
3.3 (1.95.8)
1.6 (0.83.0)
0.8 (0.32.6)
95.3 (92.597.0)
95.4 (93.396.8)
94.4 (91.596.4)
0.3 (0.02.0)
0.2 (0.01.3)
0.3 (0.01.9)
Not recorded
4.4 (2.77.1)
4.4 (3.06.5)
5.3 (3.48.1)
6.6 (6.36.9)
6.5 (6.26.7)
6.3 (6.06.6)
36.1 (31.341.2)
58.0 (53.962.0)
86.1 (82.189.3)
3.1 (1.75.4)
4.8 (3.36.9)
6.4 (4.39.4)
Sodium level
Normal (134142 mEq/L)
Low (< 134 mEq/L)
High (> 142 mEq/L)
Not evaluated
0.3 (0.041.9)
1.1 (0.52.4)
1.7 (0.73.7)
60.6 (55.465.5)
36.1 (32.240.2)
5.8 (3.88.8)
Glucose level
Normal (65100 mg/dL)
Low (< 65 mg/dL)
Not evaluated
38.9 (34.044.0)
63.9 (59.867.8)
94.2 (91.296.2)
0.6 (0.12.2)
No observations
No observations
60.6 (55.465.5)
36.1 (32.240.2)
5.8 (3.88.8)
Patterson et al.
TABLE 1: Baseline Population Characteristics (continued)
Downloaded from www.ajronline.org by 114.121.237.109 on 01/04/17 from IP address 114.121.237.109. Copyright ARRS. For personal use only; all rights reserved
Variable
CT Imaging Performed
CT Imaging Not
Performed (n = 360)
Unmatched (n = 562)
Matched (n = 360)
0.3 (0.02.0)
0.2 (0.01.3)
No observations
No observations
0.4 (0.11.4)
0.6 (0.012.2)
Not evaluated
99.7 (98.0100.0)
99.5 (98.499.8)
99.4 (97.899.9)
31.7 (27.136.7)
54.1 (49.958.2)
80.3 (75.884.1)
WBC count
Normal (3.510.5 K/L)
Low (< 3.5 K/L)
0.8 (0.32.6)
1.6 (0.83.1)
2.2 (1.14.4)
7.2 (5.010.4)
7.5 (5.610.0)
9.2 (6.612.6)
60.3 (55.165.2)
36.8 (32.940.9)
8.3 (5.911.7)
31.3 (26.836.4)
55.3 (51.259.4)
80.8 (76.484.6)
Not evaluated
Hemoglobin level
Normal ( 11.6 g/dL)
Low (< 11.6 g/dL)
Not evaluated
8.3 (5.911.7)
7.8 (5.910.4)
10.8 (8.014.5)
60.3 (55.165.2)
36.8 (32.940.9)
8.3 (5.911.7)
38.3 (33.443.5)
60.3 (56.264.3)
87.5 (83.790.5)
Platelet count
Normal
Low
Not evaluated
Return visit within 30 days
1.4 (0.63.3)
2.8 (1.74.6)
4.2 (2.56.8)
60.3 (55.165.2)
36.8 (32.940.9)
8.3 (5.911.7)
21.1 (16.925.3)
11.2 (8.613.8)
10.3 (7.113.4)
c apture the effect of CT on subsequent clinical outcomes and resource use beyond the
confines of a single ED visit. As the national
focus expands from single visits to episodes
of care, we will need an understanding of the
role of ED management on subsequent care
trajectories [23].
In addition to identifying this relationship
for policy makers, our work also expands
on recent studies showing the ability to feasibly use clinical data obtained for EHRs to
measure the quality and efficiency of acute
care. Most important, we were able to measure the efficiency of imaging use on the basis of the patients chief complaint, not the
discharge diagnosis. This approach has not
only been recommended by the emergency
medicine community [24], but is also likely a
better reflection of the undifferentiated clinical picture by which patients present to the
ED. Using a combination of structured chief
complaintbased EHR data entries and future natural languageprocessing algorithms,
emergency medicine quality measures could
be substantially improved to reflect the value
of acute diagnostic risk stratification. In addition, by incorporating numerous clinical
data elements not available in administrative
claims, we were able not only to effective-
W122
this reimaging more likely represents inappropriate use than index imaging. However,
further study is needed.
Limitations
The associations described in this study
must be interpreted with care: although significant, they reflect complex relationships
among the underlying variables, including
physician and patient knowledge and expectations, and underlying biologic and social
determinants of health. Although this study
raises interesting associations, none of these
should be considered prognostic for an individual patient. The association identified in
this retrospective study should not be interpreted as indicating that CT use decreases revisits in a causative relationship. Future work
should seek to prospectively study patients
care trajectories after initial visits for headache to understand the influence of imaging
on patient and provider behaviors.
Our inclusion criteria, which used a textbased search method, may not have captured
all patients presenting for headaches (e.g., a
chief complaint of migraine would not be included in the study, whereas migraine headache would). The available database provided
information on whether CT was performed but
Downloaded from www.ajronline.org by 114.121.237.109 on 01/04/17 from IP address 114.121.237.109. Copyright ARRS. For personal use only; all rights reserved
Downloaded from www.ajronline.org by 114.121.237.109 on 01/04/17 from IP address 114.121.237.109. Copyright ARRS. For personal use only; all rights reserved
Patterson et al.
22. Rusanov A, Weiskopf NG, Wang S, Weng C. Hidden in plain sight: bias towards sick patients when
sampling patients with sufficient electronic health
record data for research. BMC Med Inform Decis
Mak 2014; 14:51
23. Wiler JL, Beck D, Asplin BR, et al. Episodes of
care: is emergency medicine ready? Ann Emerg
Med 2012; 59:351357
24. Griffey RT, Pines JM, Farley HL, et al. Chief
complaint-based performance measures: a new
W124