Spray For Life FAQ

Frequently Asked Questions About Spray For Life
Product Questions | Customer Service | Privacy Policy | Product Guarantee | General Info
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Spray For Life and its Patented Technology

What is Spray For Life?
Why do I need to take Spray For Life?
Which Spray For Life products are available?
What makes Spray For Life so unique and is it patented?
What is Nanotechnology?
How is nanotech different from biotech?
How is Spray For Life related to Nanotechnology?
What is this patented NanoSyzed process?
Why is Nano safe?
What makes Spray For Life better than other dietary supplements?
What makes Spray For Life taste so incredibly good?
When are the best times to take Spray For Life?
What is in Spray For Life?
Are all Spray For Life products made in the USA?
Does Spray For Life contain any sugar?
Are Spray For Life products safe for diabetics?
What alternative natural sweeteners are used in Spray For Life?
How much does each Spray For Life pump hold?
Why do I take Spray For Life more than once a day?
What is not in Spray For Life?
Will Spray For Life interact with my prescription medication?
Are the flavors used in Spray For Life all natural?
My spray bottle has accumulated residue, what should I do?
Has Spray For Life products been approved by the FDA?
Can I take Spray For Life on a plane?
Check with your doctor before taking Spray For Life if
Is it safe to combine several Spray For Life products together?
How long does one bottle of Spray For Life last?
What is the Spray For Life bottle made of and is it safe?
Is Spray For Life affected by extreme temperatures?
Is it harmful to take outdated/expired Spray For Life?
Is Spray For Life Gluten-free and safe for individuals with sensitivities?
Are all Spray For Life products TSA compliant?
Do larger individuals need to take more than the standard dose?
What is Shban?
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Ingredients used in Spray For Life and Why?

In the Nano B-12, why Cyanocobalamin rather than Methylcobalamin?
In the Nano COQ10, why Ubiquinone rather than Ubiqunol?
What is Citric Acid?
What is Potassium Sorbate?
What is Vegetable Glycerine?
What is Jujube Extract?
What is Adenosine?
What is an Amino Acid Complex?
What is Garcinia Cambogia and why is it in the Sweet & Slim?
Do We Really Need Vitamin Supplements?
Should We Take Vitamins Daily And How Nutritionally Deficient Are We?
What are Vitamins?
What is Vitamin A?
Sprayforlife.com
2016 NanoSynergy Worldwide. All Rights Reserved.
Contact NanoSynergy Worldwide at Phone: Toll Free: (877) NSW-NANO (679-6266)
NanoSynergy, NanoMist, and Spray For Life are registered trademarks.
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What is Vitamin B1?

What is Vitamin B2?
What is Vitamin B3?
What is Vitamin B5?
What is Vitamin B6?
What is Vitamin B7?
What is Vitamin B8?
What is Vitamin B9?
What is Vitamin B12?
What is Vitamin C?
What is Choline?
What is CoQ10?
What is Vitamin D?
What is Vitamin E?
What is Vitamin K?
What is Melatonin?
What is Selenium?
What is Zinc?
Order and Payment

1. How do I place an order?
2. A product I wish to buy is out of stock. Can I still order it?
3. How can I find out the status of my order?
4. Can customers outside the U.S. order from the website?
5. Can I make changes to my order after I have submitted it?
6. Can I cancel my order once it has been submitted?
7. I order the same products. Can I be set up to receive them automatically?
8. Will you notify me if there are problems with my order?
9. What forms of payment do you accept?
10. Do I need to pay sales tax with my order?
11. If one or more of my items are on backorder, when will I receive my order?
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Shipping
When will my order ship?
What shipping carrier do you use?
What are my shipping options? How much does each cost?
Do you refrigerate products during shipping?
How can I determine the exact shipping cost for international orders?
Will you notify me when my order has been shipped?
Can I ship to an address other than my own?
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Return Policy
What is your Easy Return Policy?
How do I return an item?
What should I do if my items arrive damaged or defective?
What should I do if I received the wrong item?
Privacy Policy and Terms & Conditions

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What information does Spray For Life collect?

How does Spray For Life use or disclose the information it collects?
How can I correct, update, or delete my information?
What happens to my information if Spray For Life is sold to or merges with another
company?
Sprayforlife.com
Spray For Life and its Patented Technology
Q1: What is Spray For Life?
A: Spray For Life is the most technologically advanced dietary supplements globally available on the
market today.
Q2: Why do I need to take Spray For Life?

A: Vitamins help release energy from our food and help build muscle, bone, blood and other vital tissue.
With a regular supply of nutrients, we can maintain good health and normal growth. Since the body
does not store all essential vitamins for long periods of time, some can be supplemented on a regular
basis. Spray For Life multi-vitamin can be taken to help support complete nutrition.
Q3: Which Spray For Life products are available?

A: Following Nano products are available:
Nano B-12 Booster

Nano Super B-Complex
Nano COQ10
Nano Sweet & Slim
Nano Melatonin
Nano Multi-Vitamin
Nano Vitamin D-3
Shaban
Q4: What makes Spray For Life so unique and is it patented?

A: Spray For Life is so unique it was the first patented nutraceutical nanotechnology process patent
(6,861,066) filed in the United Patent and Trademark Office in Washington, D.C. Its NanoMist
delivery system presents nutraceuticals that are much more bioavailable and efficacious than any
other dietary supplements.
Q5: What is Nanotechnology?

A: Nanotechnology is science, engineering, and technology conducted at the nanoscale, which is about
1 to 100 nanometers. Nanoscience and nanotechnology are the study and application of extremely
small things and can be used across all the other science fields, such as chemistry, biology, physics,
materials science, and engineering.
Q6: How is nanotech different from biotech?

A: Based on the definition of nanotech given above, biotech can be thought of as a subset of nanotech -
"nature's nanotechnology." Biotech uses the molecular structures, devices, and systems found in
plants and animals to create new molecular products. Nanotech is more general, not being limited
to existing natural structures, devices, and systems, and instead designing and building new, nonbiological ones. These can be quite different: harder, stronger, tougher, and able to survive a dry or
hot environment, unlike biology. For example, nanotech products can be used to build an
automobile or spacecraft.
Q7: How is Spray For Life related to Nanotechnology?

A: Everything in nature is at the nanoscale or atomic levels, and Spray For Life is no exception. Spray
For Life utilizes a patented NanoSyzed process that allows the ingredients to be processed and
stabilized resulting in and end-product as nature intended. This allows these nanoparticles to be
Sprayforlife.com
made available to be dispensed through an intraoral spray which increases absorption and
bioavailability.
Q8: What is this patented NanoSyzed process?

A: This NanoSyzed patented (6,861,066) process is a cold process. It allows a formulation to pass
through fixed-geometry micro channels within its unique interaction chamber. As a result, the
product stream accelerates to high velocities (faster than the speed of sound to 1500 ft/sec for 3-5
nanoseconds); creating shear rates within the product stream that are orders of magnitude greater
than any other conventional means. Our products experience identical processing conditions,
producing the desired results, including: uniform particle and Nanosyze reduction. This is
achieved without excessive heat or breaking any chemical bonds (i.e. mimic shear from chewing).
Q9: Why is Nano safe?

A: Spray For Life uses Nanofluidized product formulations consisting of a highly concentrated
intraoral spray dispensing system. This intraoral spray allows for absorption through the
circulatory system, which reduces first pass liver metabolism.
Spray For Life researchers have tested and screened over a thousand raw ingredients while
observing very large differences in particle size and solubility. We then have developed a
proprietary testing methodology to identify raw ingredients that have the smallest particle size
combined with natural methods to balance the hydrophobicity (HLB/LogP) and ionic state (pKa,
zeta potential) in a water based delivery vehicle.
We have identified numerous food approved, GRAS, and natural ingredients to restore the solubility
and bioavailability of most dietary supplements. Our technology delivers completely natural, NOT
synthetic, molecules to your system in a form that most closely mimics the hydrated structure
found in nature. The NanoSyzed process then keeps these ingredients in a stable form while
remaining in solution, and without reaggregation or precipitation.
Q10: What makes Spray For Life better than other dietary supplements in pill, tablet gelcapsule or liquid form?
A: Spray For Life can be taken at any time at any place without the need for water or food. Spray For
Life addresses the difficulty 4 out of every 10 consumers (40% of the Adult U.S. population)
experience while swallowing pills, tablets and gelcaps as well as inefficient assimilation and
absorption. And with Spray For Life you will not experience any stomach upset.
Q11: We have taken liquid vitamins and sprays before, but how do you make Spray For
Life taste so incredibly good?
A: What you are experiencing with the flavor of Spray For Life is over 15 years of flavoring expertise
combined with a team of other specialists that have over 50 years. All the flavors used in Spray For
Life are natural and contain no fruit juice.
Q12: When are the best times to take Spray For Life?
A: The simple answer is "any time." Our products are so convenient there is no need for water, and
small enough to be carried with you or one at the office for super convenience. Since the products
are in a nano-liquid state, digestion has little or no affect in there absorption capabilities. There is
no need to eat food before consuming any of your Spray For Life products, like you would with
other dietary supplements.
Here are a few ideas:
Morning: Let Spray For Life fuel your body first thing allowing the nutrients needed for a
demanding day. Several sprays will keep you going strong and keep you alert.
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After Lunch: Research shows that over 70 percent of us hit the wall after lunch. Let Spray For Life
help you get over that wall and have an alert, productive afternoon.
Workouts: Looking for motivation to workout? Make Spray For Life part of your healthy lifestyle.
Sports: Be the leader on the field, court, track or course and stay there stronger and longer with
Spray For Life .
Travel: Anyone who travels frequently knows how tiring it can be especially when it comes to jet
lag. Have the B-12 Booster fuel your body and have the Melatonin assist your body to rest as it may
help to adjust for time differential.
Weekends/Vacations: Action-packed weekends and vacations require a lot of energy. Whether
youre doing the lawn or garden work, going on a hike or playing on the beach, Spray For Life can
give you the extra edge you need no matter what the demand.
Q13: What is in Spray For Life?

A: Spray For Life contains natural ingredients that assist your body to perform at its optimum level.
Q14: Are all Spray For Life products made in the USA?
A: YES! Spray For Life products have been patented, manufactured and tested in the US since 1997.
We offer products that are unsurpassed in quality and efficacy and are backed by clinical science.
Our customers include a broad scope of international consumers and distributors, medical and
healthcare practitioners, professionals, pharmacies, and the internet. What distinguishes Spray For
Life from the other supplement companies is the fact that our branded supplements are produced
and manufactured in the USA using in most cases, only USA manufactured ingredients. All
manufacturing is performed under highly regulated procedures according to good manufacturing
practices (GMP). Rest assured, Spray For Life delivers only pure, quality-controlled nutritional
supplements.
Q15: Does Spray For Life contain any sugar?

A: Absolutely not! Only alternative natural sweeteners (diabetic friendly) are used in Spray For Life.
Q16: Are Spray For Life products safe for diabetics?
A: All our spray products contain small amounts of sweeteners and these sweeteners are used by
diabetics as an alternative to sugar. They are either low glycemic or have 0 glycemic index.
However, diabetes is a disease which affects sufferers in different ways, so a diabetic user should
monitor blood sugar levels just to make sure that there are no adverse reactions. Many of our
customers are diabetics and have experienced no problems when using Spray For Life.
Q17: What alternative natural sweeteners are used in Spray For Life?
A: The best natural sweeteners go into our products.
1) Stevia is a non caloric 0 glycemic index sweetener. This sugar substitute derived from the leaves
of the stevia plant that is significantly sweeter than sugar is ideal for low-carb diets and those
watching their sugar intake. Most often considered an herb or dietary supplement, its approval for
use as an additive by the FDA was in 2008.
300 times sweeter than sugar

Helps to keep the body's blood sugar in balance
Low caloric, aids weight management
Beneficial for hypoglycemics
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Increases energy levels and mental activity

Assists in Lowering hypertension
Appears to increase levels of HDL, or good cholesterol
Not all stevia products are equal. For more information on which Stevia Spray For Life utilizes,
please refer to the following link Steviasuav
2) Xylitol is a 100% natural product, a sweetener that occurs naturally. It can be found in berries,
fruit, vegetables, mushrooms and hardwood trees. It also occurs naturally in our bodies in fact, an
average size adult manufactures up to 15 grams of xylitol daily during normal metabolism.
Xylitol is a naturally occurring carbohydrate, that looks and tastes just like regular table sugar. It is
a natural sweetener that can be extracted from any woody fibrous plant material.
Safe For Diabetics -Unlike sugar, xylitol is not easily converted to fat.
Helps Prevent Cavities-Since it is a non-fermentable sugar, it cannot be converted to acid
by oral bacteria. Thus, the alkaline-acid balance in the mouth is maintained, which helps in
preventing cavities.
Helps Prevent Ear Infections-Xylitol can also be used as medicine in prohibiting certain
bacterial growth to help prevent ear infections in young children. It will also help clear out
earwax and prevent the growth of harmful bacteria in the pharyngotympanic tubes,
connecting the nose and ear.
Slows the Growth of Candida-Xylitol helps prevent bad breath, ulcers, and stomach cancer
by slowing down the growth of Candida Albicans (a serious yeast infection), and other
harmful bacteria like H. pylori.
May Improve Bone Density-According to research from the University of Oulu in Finland,
xylitol was shown to help improve bone density in rats. This indicates it has potential as a
treatment for osteoporosis in humans.
For more information on which Xylitol Spray For Life utilizes, please refer to the following link
Global Sweet and not all Xylitol products are equal xylitol-brand-comparison.
Another link for information: xylitol.org
3) Vegetable Glycerine is 100% pure, safe and low glycemic index sweetener. It contains no
carbohydrates or cholesterol. Derived from coconut or palm oil, this product is excellent for use in
raw foods as well as in baked and cooked foods.
Glycerine is not chemically related to sugar and seems to have no affect on insulin and blood sugar
levels making it a safe alternative for diabetics and people with candida yeast overgrowth. It also
does not feed the bacteria that form plaques and cause dental cavities.
A little goes a long way - only one tablespoon of vegetable glycerine is equivalent to about 1/4 cup
of sugar. Vegetable Glycerine is pure Kosher grade and is suitable for vegans and vegetarian.
4) Oh! So Sweet Reb-A/Citrus Extract Blend 150 is a natural sweetener and flavor enhancer
approximately 150 times sweeter than sugar which is Kosher Certified. It contributes zero calories
& zero carbohydrates to finished products. It is derived from Stevia (Reb-A) and Citrus Aurantium
(bitter orange peel), liquid in form. The citrus extract has been blended with Reb-A (97%) to
increase the sweetness intensity and improve the flavor of our Spray For Life product. OH! So
Sweet meets all regulatory requirements in the U.S.A, European Union and Canada.
Q18: How much does each Spray For Life pump hold?
A: Each pump holds .88 fl oz. (26 ml), which is a 30 day (1 month) supply when used as directed,
which is 3 sprays twice per day or 180 metered sprays. The only exceptions occur when taking
Melatonin, 6 sprays prior to sleep and Sweet & Slim (weight management), 2 sprays three times
daily.
Sprayforlife.com
Q19: Why do I take Spray For Life more than once a day?
A: Just as you eat several times a day, we recommend that you take your Spray For Life products at least
twice a day so that your body is well fueled and able to tackle the stressful situations that most of us
experience throughout the day.
Q20: What is not in Spray For Life?

A: All Spray For Life products do not contain GMOs (Generally Modified Organisms), sugar, fruit
juice, salt, yeast, wheat, gluten, corn, milk, egg, soy protein, MSG, shellfish, preservatives or artificial
flavors and colors. It also does not contain fillers, binders, wax, shellac, talcum, animal gelatin or any
other excipients.
Q21: Will Spray For Life interact with my prescription medication?

A: We stress that any person taking medication under the care of a physician should discuss the use of
all other products with the physician. The physician needs to have full disclosure to all products you
are taking in order to fully evaluate your treatment.
One should also remember that the nutrients used in our products are identical to those found
naturally in food.
Q22: Are the flavors used in Spray For Life all natural?
A: Yes! All flavors are natural and are sourced from the best flavoring houses in the world (USA).
Please find the following links to two of our flavor houses for more information.
E.A. Weber and Company Architects of Flavor since 1902
Prinova -Your Secret Ingredient since 1978
Q23: My spray bottle has accumulated residue around the spray mechanism, what should
I do?
A: The fine mist on the sprayer is intended to disperse the formulation throughout the mouth for
better absorption capabilities and may have a tendency to leave somewhat of a residue over time.
We recommend that you periodically rinse your sprayer under lukewarm water to remove any
residual buildup.
Q24: Are the ingredients in Spray For Life products approved by the FDA?
A: The FDA acknowledges the safety of nutritional supplements that fall under the Dietary Supplement
Health & Education Act (DSHEA). Spray For Life ingredients are all covered under DSHEA*.
Q25: Can I take Spray For Life on a plane?

A: All Spray For Life products are TSA compliant in the 25ml Go Anywhere Spray Travel Bottle as a
carry-on when traveling via air.
Q26: Check with your doctor before taking Spray For Life if
A:
You are currently taking any prescription medicines.

You have been advised by your physician to avoid certain vitamins and minerals.
You have a medical condition that makes you concerned about taking it.
You are concerned about taking it for any reason.
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Other concerns?
A:
Diabetics: Spray For Life is sugar free. However, check with your doctor before taking
Spray For Life if you have concerns about how it may affect you.
There are no animal products added to Spray For Life.
Q27: Is it safe to combine several Spray For Life products together?

A: YES. Our in-house formulators take into consideration the very active modern lifestyle when
developing Spray For Life products and have designed them to work in conjunction with each
other. Spraying different products at the same time will not decrease their effectiveness or harm
you.
Q28: How long will one bottle of Spray For Life last?
A: On average most sprays last for one month as directed. Some formulas such as Sweet & Slim is
recommended by taking 2 sprays 3 times a day, and if you are experiencing hunger or would like a
snack, so it may last less than one month.
Q29: What is the Spray For Life bottle made of and is it safe?
A: Polyethylene Terephthalate (PET) is globally recognized as a safe, recyclable packaging material.
Most single-serve plastic bottles, including those for water, soft drinks and juices, are made with
PET, which can be recycled and does not contain bisphenol-A (BPA). BPA is an industrial chemical
that has been used to make certain plastics and resins since the 1960s. Please find the following link
for more information regarding the safe uses of PET plastics for food products The Facts on PET.
Q30: Is Spray For Life affected by extreme temperatures?

A: Spray For Life should not be exposed to temperatures greater than 49C (approximately120F) for
any extended periods of time. Like any food products, high temperature will spoil the ingredients
over time. We do not recommend leaving your Spray For Life products in your automobile during
the summer months. Also, we do not recommend refrigerating or freezing your Spray For life
products, preferably store at room temperature.
Q31: Is it harmful to take outdated/expired Spray For Life?

A: All our products are assigned an expiration date, which is based upon extensive stability studies.
We guarantee the potency of the product until the last day of the month noted on the package.
There is no evidence to indicate that the ingredients in the product would be harmful if consumed
beyond the expiration date. You may not, however, be receiving the amount of each vitamin or
mineral listed on the label. The potency of the ingredients slowly diminishes over an extended
period of time, and the expiration date is determined by the least stable ingredient in the product.
We recommend that the product not be used after the expiration date.
Q32: Is Spray For Life gluten-free and safe for individuals with sensitivities?
A: Yes. All Spray For Life products are gluten-free.
Q33: Are all Spray For Life products TSA compliant?
A: Yes, the Transportation Security Administration (TSA) allows 3.4 ounce (100ml) bottle or less (by
volume). All Spray For Life products meet compliance with 25ml. per vial.
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Q34: Do larger individuals need to take more than the standard dose?
A: No. Spray For Life is not dispensed according to weight or size of individuals.
Q35: What is Shban?
A: SHBAN IS AN ALCOHOL FREE HAND SANITIZER.
Lasts up to four (4) hours (not 1 minute like alcohol gels)

Is gentle on hands (it will not dry or crack your hands from repeated use)
Is odorless
Is colorless and won't stain most clothes and jewelry. Is a green product that won't
endanger the environment
Is made in the USA
SHBAN's active ingredient is FDA Approved as an antimicrobial and as a hand scrub.
Is safe to be put on a child's hands
SHBAN is not flammable and is not a fire hazard
Is TSA compliant in the 1 oz Go Anywhere Spray Travel Bottle as a carry-on when traveling
via air.
For more information, please refer to Shban Power Point Presentation
Ingredients used in Spray For Life and Why?
Q1: In the Nano B-12, why Cyanocobalamin rather than Methylcobalamin?
A:
A short list of benefits of Cyanocobalamin vs Methylcobalamin

1. Stability of the Cyanocobalamin allows for a longer shelf life and ease of use.
2. Cyanocobalamin has a lower production cost than Methylcobalamin and is easier to work
with on a manufacturing level.
3. Cyanocobalamin is naturally converted to Methylcobolamin as the body needs it and it is
stored up to 6 months in the liver.
4. Cyanocobalamin is naturally available in foods mainly dairy, fish, liver, beets and meat.
5. Methylcobalamin is immediately available as an active form of B-12, but dissipates quickly.
It is most appropriate for athletes seeking immediate availability and patients with severe
nerve damage or liver disorders (incapable of converting Cyanocobalamin to
Methylcobalamin)
6. Methylcobalamin causes what is called a Methyl crash due to the speed of utilization.
Methylcobalamin is rapidly utilized (not requiring Liver uptake and conversion). However,
it is used up quicker creating a Methyl Crash when used up, usually in a few minutes.
7. Cyanocobalamin is smoother as it is introduced into the body functions in a gradual
continual basis.
8. Cyanocobalamin has the CN ion added to increase the stability of the molecule in the
bloodstream and in its product forms. It loses the CN ion when it is converted in the body to
an active form. The amount of cyanide liberated in this process is so small that its toxicity is
negligible.
For the reasons explained above Cyanocobalamin is most appropriate for the majority of
consumers who have the ability to store up Cyanocobalamin in the liver and release it as
Methylcobalamin or other B-12 vitamers when needed by the body.
For additional information, please find links to experts who recommend Cyanocobalamin rather
than Methylcobalamin.
Sprayforlife.com
1. Dr. Andrew Weil uses Spray For Life B-12 and recommends it as the Best way to get B-12?.
2. In depth study in why cyanocobolamin is a great source of B-12 by Super Nutrition USA
3. Cyanocobalamin is a safe and effective solution for any concern related to B12 deficiency by
Mark A. Kaye, DC, Director of Technical Services for Metagenics, Inc.
Q2: In the Nano COQ10, why Ubiquinone rather than Ubiqunol?

A: Coenzyme Q10 (CoQ10) is critical to your healthespecially as you age. This compound is the spark
that fuels energy production in every cell in your body, including your heart, which is your bodys
biggest energy user.
Ubiquinone is the oxidized form of CoQ10. Once ingested, enzymes reduce ubiquinone to
ubiquinol, the active antioxidant form that makes up practically all of the circulating CoQ10 in the
body. Ubiquinol was developed as a commercial supplement a couple of years ago, and one small
study suggested that it had excellent absorption properties when compared with the powdered
form of CoQ10.
Note: Our Spray For Life Nano COQ10 is in a liquid form and encapsulated in Vitamin E for superior
absorption and bioavailability. The product is superior in all aspects to the present forms of COQ10
and the spray makes it more convenient and much more utilized.
The simple truth is that both forms are needed by the body, and CoQ10s location in the body
determines the form it takes. Inside the cells, where energy is produced, ubiquinone is in great
demand. However, outside the cells, in the blood and cell membranes, ubininol works as an
antioxidant.
Importantly, ubiquinone and ubiquinol form a redox pair. This means each one can be easily
converted to the other by the body.
Given the fact that the body can switch the two substances back and forth to meet its own
requirements, the argument that ubiquinol is the biologically active form of CoQ10 is not valid.
Additionally, while claims have been made that adults over 40 have difficulty reducing ubiquinone
to ubiquinol, a recent human study indicates otherwise.
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Following the Science

Its ironic that ubiquinone is often viewed as inferior to ubiquinol, considering that the ubiquinol
found in animal protein is converted to ubiquinone through the process of cooking before it is
eaten.
Similarly, ubiquinol taken as a supplement is quite unstable in the stomach and is converted back to
ubiquinone before absorption. This means that no matter which form of CoQ10 the consumer
chooses to ingest, its ubiquinone that is absorbed into the body.
Perhaps more importantly, in the four years since ubiquinol was presented as an alternative to
ubiquninone, only one human clinical trial on the substance has been published in the peerreviewed scientific literature. In marked contrast, there have been hundreds of clinical studies
showing ubiquinone is an effective supplement for a wide variety of illnesses and conditions.
For additional information, please find links to experts who recommend Ubiquinone rather than
Ubiquinol.
CLINICAL RESEARCH BULLETIN

Bioavailability of Ubiquinone versus Ubiquinol - BRIAN DIXON* PHD, TONI MCKINNON* RN,
CCRP, ERIK SCHNEIDER*, MARK BROWN* PHD, TIM WOOD* PHD, JOHN CUOMO* PHD. This
clinical bulletin was undertaken to help clarify current discrepancies in the marketplace
regarding which form of CoQ10 is the most bioavailable.
Dr. Stephen Sinatra is a highly respected and sought-after cardiologist and nutritionist with
more than 30 years of clinical practice, research, and study.
What's the Best Form of CoQ10, Ubiquinone? - by Dr. Stephen Sinatra

Q3: What is Citric Acid?
A: Citric acid is a very useful and effective preservative, obtained from naturally occurring organic
acids. It exists in many different fruits and vegetables, but is especially concentrated in lemons and
limes. Citric acid is used extensively in the food, beverage, cosmetic, and pharmaceutical industries.
It has been recognized as safe by all major national and international food regulatory agencies, and
is also approved by the US Food and Drug Administration and in Europe for use in food. Citric acid
is used for many different reasons, including (but not limited to):
Antioxidant and preservative properties

prevents rancidity and bacteria growth
Astringency and Acidity
Adjusts pH
Stabilizes the ingredients, color, taste, and flavor of a product
Rapidly biodegradable
Furthermore, since citric acid is present in almost every life form, it is consequently easily
metabolized and eliminated from the body.
Q4: What is Potassium Sorbate?

A: Potassium sorbate is a salt of sorbic acid which is naturally found in some fruits (like the berries of
mountain ash). It is a white crystalline powder that has antimicrobial properties. It is one of the
safest and most commonly used preservatives today. In foods, potassium sorbate increases shelf life
and reduces the risk of food-borne illnesses, without adversely affecting taste, color or flavor.
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Safety
Potassium sorbate has been generally recognized as safe for use in foods and personal care
products. It has been cleared as a food preservative by the U.S. Food and Drug Administration based
on extensive testing. Potassium sorbate is well-tolerated in most people, being easily metabolized.
Allergic reactions are rare.
For additional validation of its safety - Final Report on the Safety Assessment of Sorbic Acid
and Potassium Sorbate
Q5: What is Vegetable Glycerine?

A: Vegetable Glycerine is 100% pure, safe and low glycemic index sweetener. It contains no
carbohydrates or cholesterol. Derived from coconut or palm oil, this product is excellent for use in
raw foods as well as in baked and cooked foods.
Glycerine is not chemically related to sugar and seems to have no affect on insulin and blood sugar
levels making it a safe alternative for diabetics and people with candida yeast overgrowth. It also
does not feed the bacteria that form plaques and cause dental cavities.
A little goes a long way - only one tablespoon of vegetable glycerine is equivalent to about 1/4 cup
of sugar. Vegetable Glycerine is pure Kosher grade and is suitable for vegans and vegetarian.
Q6: What is Jujube Extract?

A: What it is: Jujube is a fruit with benefits that are well known since ancient times.
Why we use it: Jujube fruit is used as herbal medicine for thousands of years in China and other
Asian countries.
HEALTH BENEFITS OF JUJUBE
Jujube fruit benefits are mainly offered by the nutrients present in it.
1. Because of mucilaginous property of the fruit, it acts as herbal medicine to treat sore throat.
2. As this fruit is high in vitamin A, C and potassium, it strengthens the immune system of the body.
Thus it helps in prevention of common colds and cough.
3. It helps in the formation and maintenance of the blood stream, body hormones, bones, muscles,
skin, hair, body enzymes and neurotransmitters.
4. It is also loaded with 18 out of the 24 important amino acids. It helps in the formation of more
than 50,000 proteins of the body. All this, actually triggers the wound healing process.
5. It has soothing effect on the nervous system and acts as a natural sedative.
6. It relieves stress and anxiety.
7. Jujube fruit helps lower blood pressure.
8. Jujube fruit boosts your immune system.
9. Jujube helps cure some of the liver diseases. It is found that the jujube offers protection against
liver injury by acting as an antioxidant.
10. Jujube fruit is used to treat anemia and purpura.
11. It has anti-oxidant properties. So it helps in delaying the process of skin aging.
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12. One of the most important jujube fruit benefits is that it inhibits the growth and movement of
free radicals. Vitamin C is a good antioxidant and helps to control the growth of the tumor causing
cells and cells that can lead to cancers.
13. The berries are blood purifier and an aid to digestion.
14. When jujube extract is combined with certain herbs like ginger, licorice, and mint, it soothes
achy throat muscles.
15. The jujube extract is useful in control of cold and flu (fever).
16. It has anti-carcinogenic properties.
17. According to the recent study, water extract of the jujube fruit was found effective for inhibiting
the tumor causing cells and cells that can lead to leukemia.
18. The dried ripe fruit is a mild laxative and expectorant.
19. The fruit seed is astringent; tonic to the heart and brain; allays thirst.
20. The alkaloids and other chemicals present in the jujube seed can help you get rid of anxiety and
provide antioxidant protection to cells.
21. The plant is considered to have anti tubercular properties.
22. They are also prescribed to stop nausea and vomiting and for relief from abdominal pain in
pregnancy.
23. Jujube fruits are also found useful in the treatment of itching, which is caused by several skin
disorders, hysteria.
24. It acts as energy booster in cases of fatigue, loss of energy and lack of appetite.
So, incorporate this low calorie fruit in your diet and reap several of jujube fruit benefits.
Q7: What is Adenosine?

A: Adenosine is another neuro-transmitter, like Melatonin, which seems to have a significant effect on
our sleep. Adenosine is perhaps better known as part of the compound Adenosine Triphosphate,
ATP, which is the energy source of the bodys cells.
Without the phosphate part, Adenosine is produced during the day and, at night, attaches to
receptors in the brain which, in laymans terms, switches off cells in arousal centres and makes
you feel drowsy. Overnight, the supply of Adenosine is used up, allowing you to wake up and feel
more alert in the morning.
The fact that Adenosine has a link to the cellular energy source, ATP. may indicate that the need to
sleep is connected to energy levels in the body.
Q8: What is Garcinia Cambogia and why is it in the Sweet & Slim?
A: Garcinia Cambogia is a small, pumpkin-shaped fruit, sometimes called tamarind. Though native to
Indonesia, it is also grown in India, Southeast Asia, and West and Central Africa. It has long been
used in traditional South Asian dishes, including curries and chutneys.
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Adding this ingredient to meals is considered to be effective in making meals more filling. In some
villages in Malaysia, garcinia is used to make a soup that is eaten before meals for weight loss
because of garcinias appetite-blocking abilities.
This plant offers one of the least expensive herbal supplements on the market. The ingredient from
the rind of the fruit could hasten your weight-loss efforts. The natural extract is called hydroxycitric
acid (HCA), and researchers claim that HCA can double or triple ones weight loss.
With proper weight-loss efforts (dieting and exercising), the average person taking HCA lost an
average of four pounds a month.
Garcinia may also be great for emotional eaters. Those who participated in the study showed an
increase in their serotonin levels; hence, it may also improve mood and sleeping patterns.
How Does Garcina Cambogia Work?
The HCA extract from garcinia cambogia supplement aids in weight loss by doing two things: It
helps to block fat, and it suppresses your appetite.
HCA blocks fat by inhibiting a key enzyme that your body needs to make fat from carbohydrates:
Citrate lyase. Usually carbohydrates or sugars that are not used immediately or stored in other
forms are converted into fats. When HCA inhibits citrate lyase, the fat-making process is halted and
the production of LDL (bad cholesterol) and triglycerides decrease.
HCA also suppresses appetite by increasing serotonin levels. Serotonin is a neurotransmitter in
your brain that makes you feel good. Its a target of many antidepressant medications. Having low
levels of serotonin may make you feel depressed or anxious; it drives many people into emotional
or reactive eating. By increasing serotonin levels, HCA improves mood and suppresses the drive to
react to stressful situations with food. As you eat less, your body senses this and it releases stored
fat in your fat cells.
Spray For Lifes Sweet & Slim has been testing this amazing ingredient, garcinia cambogia (Super
Citrimax) since 1997 with tremendous results. Spray For Life has been purchasing and following
the clinical results from InterHealth since that time. InterHealth is the company that supplied Dr. Oz
with the clinical trial to validate his assessment of this wonder fruit. In the last 16 years, Spray For
Life has been able to reduce the dosing and add ingredients that work synergistically in the success
of garcinia without compromising the results. This fast action spray works quickly to satisfy your
hunger needs and as a result, is a great replacement snack as it tastes just like candy.
Do we really need Vitamin Supplements?

What nutritionists have said all along is now official. It pays to take health supplements.
The American Medical Association (AMA) has reversed its previous anti- vitamin stand after
20 years, and now encourages adults to take vitamins daily. This was after a study of 38
years of scientific evidence by Harvard researchers Dr Robert Fletcher and Dr. Kathleen
Fairfield.
In reports published in the June 19 2002 edition of JAMA (Journal of the American Medical
Association), they concluded that the modern American diet is enough to prevent deficiency
diseases, but not enough to support optimal health.
"Insufficient vitamin intake is apparently a cause of chronic
diseases. Recent evidence has shown that suboptimal levels
of vitamins (below standard), even well above those
causing deficiency syndromes, are risk factors for chronic
diseases such as cardiovascular disease, cancer, and
osteoporosis. A large proportion of the general population
is apparently at increased risk for this reason."
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-- Dr Robert Fletcher and Dr Kathleen Fairfield (emphasis mine)

The conclusion is supplementing with a daily multi-vitamin is important to health, and a wise
preventive measure against disease.
Should We Take Vitamins Daily And How Nutritionally Deficient Are We?
In a massive random survey of residents of the United States (one of the wealthiest nations in the
world with arguably the best supply and variety of food) it was found that:
25 - 50% get less than the RDA of vitamin A

25% get less than the RDA of vitamin C
80 - 90% get less than the RDA of vitamin E
25% get less than the RDA of folic acid
50% get less than the RDA of calcium
... and so on.

To compound this problem, not only are we eating nutrient-deficient diets, but it appears that the
RDA (Recommended Daily Allowances) of many nutrients may actually be too low. Many research
scientists now believe that RDA levels may have been set at what is necessary to avoid obvious
signs of deficiency rather than what is needed for optimum health.
What are Vitamins?

Vitamins are organic compounds which are needed in small quantities to sustain life.
A vitamin is one of a group of organic substances, present in minute amounts in natural foodstuffs,
that are essential to normal metabolism; insufficient amounts in the diet may cause deficiency
diseases.
Put simply, a vitamin is both:
An organic compound (contains carbon).

An essential nutrient the body cannot produce enough of on its own, so it has to get it (tiny
amounts) from food.
There are currently 13 recognized vitamins.

Fat soluble and water soluble vitamins
Fat-soluble vitamins are stored in the fat tissues of our bodies, as well as the liver. Fat-soluble
vitamins are easier to store than water-soluble ones, and can stay in the body as reserves for days,
some of them for months.1
Fat-soluble vitamins are absorbed through the intestinal tract with the help of fats (lipids).
Water-soluble vitamins do not get stored in the body for long - they soon get expelled through
urine.
Water-soluble vitamins need to be replaced more often than fat-soluble ones.
Vitamins A, D, E and K are fat-soluble.
Vitamins C and all the B vitamins are water-soluble.2
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List of vitamins
What is Vitamin A?
Vitamin A is a fat-soluble vitamin that is naturally present in many foods. Vitamin A is important for
normal vision, the immune system, and reproduction. Vitamin A also helps the heart, lungs, kidneys,
and other organs work properly.
Vitamin A
- Chemical names (vitaminer) - retinol, retinal, and four carotenoids (including beta carotene).
- Deficiency may cause night-blindness and keratomalacia (eye disorder that results in a dry
cornea)
- Good sources include: liver, cod liver oil, carrot, broccoli, sweet potato, butter, kale, spinach,
pumpkin, collard greens, some cheeses, egg, apricot, cantaloupe melon, milk.
What is Vitamin B1?

Vitamin B1 is a water-soluble B-complex vitamin, also known as Thiamine (also spelled "thiamin")
or aneurine. Thiamine is involved in numerous body functions, including nervous system and
muscle functioning; the flow of electrolytes in and out of nerve and muscle cells (through ion
channels); multiple enzyme processes (via the coenzyme thiamine pyrophosphate); carbohydrate
metabolism; and the production of hydrochloric acid (which is necessary for proper digestion).
Because there is very little thiamine stored in the body, depletion can occur quickly, within 14
days.
Vitamin B1
- Chemical name (vitaminer) - thiamine

- Deficiency may cause beriberi, Wernicke-Korsakoffsyndrome
- Good sources include: yeast, pork, cereal grains, sunflower seeds, brown rice, whole grain rye,
asparagus, kale, cauliflower, potatoes, oranges, liver, and eggs.
What is Vitamin B2?

Vitamin B2 is a water-soluble B-complex vitamin, also known as Riboflavin. Riboflavin since it is
water-soluble means it is not stored in the body. You must replenish the vitamin in your body every
day.
Riboflavin works with the other B vitamins. It is important for body growth and red blood cell
production and helps in releasing energy from carbohydrates.
Vitamin B2
- Chemical name (vitaminer) - riboflavin

- Deficiency may cause ariboflavinosis
- Good sources include: asparagus, bananas, persimmons, okra, chard, cottage cheese, milk,
yogurt, meat, eggs, fish, and green beans.
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What is Vitamin B3?

Vitamin B3 is a water-soluble vitamin found in the forms of Niacin and niacinamide. Vitamin B3 is
present in many foods including yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal
grains. Niacin and niacinamide are also found in many vitamin B complex supplements with other B
vitamins.
Niacin and niacinamide are required for the proper function of fats and sugars in the body and to
maintain healthy cells. At high doses, niacin and niacinamide can have different effects. Niacin
might help people with heart disease because of its beneficial effects on clotting. It may also
improve levels of a certain type of fat called triglycerides in the blood
Vitamin B3
- Chemical names (vitaminer) - niacin, niacinamide

- Deficiency may cause pellagra
- Good sources include: liver, heart, kidney, chicken, beef, fish (tuna, salmon), milk, eggs,
avocados, dates, tomatoes, leafy vegetables, broccoli, carrots, sweet potatoes, asparagus, nuts,
whole grains, legumes, mushrooms, and brewer's yeast.
What is Vitamin B5?

Vitamin B5 is a water-soluble vitamin, also known Pantothenic acid. It is widely found in both
plants and animals including meat, vegetables, cereal grains, legumes, eggs, and milk.
Pantothenic acid has a long list of uses, although there isnt enough scientific evidence to determine
whether it is effective for most of these uses. Pantothenic acid is also used orally for osteoarthritis,
rheumatoid arthritis, Parkinson's disease, nerve pain, premenstrual syndrome (PMS), enlarged
prostate, protection against mental and physical stress and anxiety, reducing adverse effects of
thyroid therapy in congenital hypothyroidism, reducing signs of aging, reducing susceptibility to
colds and other infections, retarded growth, shingles, skin disorders, stimulating adrenal glands,
chronic fatigue syndrome, salicylate toxicity, streptomycin neurotoxicity, dizziness, and wound
healing.
Vitamin B5
- Chemical name (vitaminer) - pantothenic acid

- Deficiency may cause paresthesia
- Good sources include: meats, whole grains (milling may remove it), broccoli, avocados, royal
jelly, fish ovaries.
What is Vitamin B6?

Vitamin B6 (pyridoxine) is required for the synthesis of the neurotransmitters serotonin and
norepinephrine and for myelin formation. Pyridoxine deficiency in adults principally affects the
peripheral nerves, skin, mucous membranes, and the circulatory (blood cell) system. In children,
the central nervous system (CNS) is also affected. Deficiency can occur in people with uremia,
alcoholism, cirrhosis, hyperthyroidism, malabsorption syndromes, and congestive heart failure
(CHF), and in those taking certain medications. Mild deficiency of vitamin B6 is common.
Pyridoxine is used for preventing and treating low levels of pyridoxine (pyridoxine deficiency) and
the tired blood (anemia) that may result. It is also used for heart disease; high cholesterol;
reducing blood levels of homocysteine, a chemical that might be linked to heart disease; and helping
clogged arteries stay open after a balloon procedure to unblock them (angioplasty).
Vitamin B6
- Chemical names (vitaminer) - pyridoxine, pyridoxamine, pyridoxal

- Water soluble
- Deficiency may cause anemia, peripheral neuropathy
- Good sources include: meats, bananas, whole grains, vegetables, and nuts. When milk is dried it
loses about half of its B6. Freezing and canning can also reduce content.
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What is Vitamin B7?

Vitamin B7 (Biotin) is a water-soluble vitamin necessary for the formation of fatty acids and glucose,
which are used as fuels by the body. It is also important for the metabolism of amino acids and
carbohydrates.
Biotin is used for preventing and treating biotin deficiency associated with pregnancy, long-term
tube feeding, malnutrition, and rapid weight loss. It is also used orally for hair loss, brittle nails, skin
rash in infants (seborrheic dermatitis), diabetes, and mild depression.
Vitamin B7
- Chemical name (vitaminer) - biotin

- Deficiency may cause dermatitis, enteritis
- Good sources include: egg yolk, liver, some vegetables.
What is Vitamin B8?

Vitamin B8 is a water-soluble B vitamin usually found in a B-Complex supplement, also known as
Inositol. Inositol is used for diabetic nerve pain, panic disorder, high cholesterol, insomnia, cancer,
depression, schizophrenia, Alzheimers disease, attention deficit-hyperactivity disorder (ADHD),
autism, promoting hair growth, a skin disorder called psoriasis, and treating side effects of medical
treatment with lithium.
Inositol is also used by mouth for treating conditions associated with polycystic ovary syndrome,
including failure to ovulate; high blood pressure; high triglycerides; and high levels of testosterone.
How does it work?
Inositol might balance certain chemicals in the body to possibly help with conditions such as panic
disorder, depression, obsessive-compulsive disorder, and polycystic ovary syndrome.
Vitamin B8
- Chemical names (vitaminer) - Inositol

- Water soluble
- Deficiency may cause eye abnormalities, hair loss or alopecia or patchy baldness, memory
loss, liver excess fat, hardening and narrowing of arteries (atheriosclerosis).
- Good sources include: cereals with high bran content lecithin fruits especially bananas,
citrus fruit like oranges and grapefruit (except lemons) and cantaloupes green leafy
vegetables.
What is Vitamin B9?

Vitamin B9 (Folate or Folic acid) is a B vitamin that's important for cell growth and metabolism.
Studies show that many people in the U.S. don't get enough folic acid.
Folic acid is a key factor in the making (synthesis) of nucleic acid - nucleic acid is one of a family of
large molecules including DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
The human body does not store folic acid, we have to consume it every day in order to make sure
we have adequate amounts.
Why is vitamin B9 important?
According to the British Dietetic Association1, vitamin B9 (folic acid and folate inclusive) is vital for
several bodily functions, including:
To synthesize DNA, RNA and to repair

Aiding rapid cell division and growth
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To produce healthy red blood cells

It is important for pregnant women to have enough folic acid to prevent major birth defects
of her baby's brain or spine (neural tube defects, including spina bifida and anencephaly)
Enhances brain health. Dutch researchers reported that folic acid supplementation may
improve memory.
In 1992, the FDA (Food and Drug Administration) advised fortifying the country's food supply with
folic acid. In 1998 folic acid started being added to breads and other grains.
Vitamin B9
- Chemical names (vitaminer) Folate, folic acid, folinic acid

- Water soluble
- Deficiency may cause pregnancy deficiency linked to birth defects
- Good sources include: leafy vegetables, legumes, liver, baker's yeast, some fortified grain
products, sunflower seeds. Several fruits have moderate amounts, as does beer.
What is Vitamin B12?

Vitamin B12 is an essential water-soluble vitamin that is commonly found in a variety of foods, such
as fish, shellfish, meat, eggs, and dairy products. Vitamin B12 is required for proper red blood cell
formation, neurological function, and DNA synthesis [1-5]. Vitamin B12 is frequently used in
combination with other B vitamins in a vitamin B complex formulation. Vitamin B12 plays an
important role in supplying essential methyl groups for protein and DNA synthesis. Vitamin B12 is
bound to the protein in food. Hydrochloric acid in the stomach releases B12 from protein during
digestion. Once released, B12 combines with a substance called intrinsic factor (IF) before it is
absorbed into the bloodstream.
The human body stores several years' worth of vitamin B12 in the liver, so nutritional deficiency of
this vitamin is extremely rare. However, deficiency can result from being unable to use vitamin B12.
Inability to absorb vitamin B12 from the intestinal tract can be caused by pernicious anemia.
Vitamin B12 deficiency is common in the elderly. HIV-infected persons and vegetarians who are not
taking in proper amounts of B12 are also prone to deficiency.
Vitamin B12
- Chemical names (vitaminer) - cyanocobalamin, hydroxycobalamin, methylcobalamin
- Water soluble
- Deficiency may cause megaloblastic anemia
- Good sources include: fish, shellfish, meat, poultry, eggs, milk, and dairy products. Some
fortified cereals and soy products, as well as fortified nutritional yeast.
Vegans are advised to take B12 supplements.
References
1. Herbert V. Vitamin B12 in Present Knowledge in Nutrition. 17th ed. Washington, DC:
International Life Sciences Institute Press, 1996.
2. Herbert V, Das K. Vitamin B12 in Modern Nutrition in Health and Disease. 8th ed. Baltimore,
MD: Williams & Wilkins, 1994.
3. Combs G. Vitamin B12 in The Vitamins. New York: Academic Press, Inc., 1992.
4. Zittoun J, Zittoun R. Modern clinical testing strategies in cobalamin and folate deficiency.
Sem Hematol 1999;36:35-46. [PubMed abstract]
5. Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes: Thiamin,
Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline.
Washington, DC: National Academy Press, 1998.
What is Vitamin C?
Vitamin C (ascorbic acid) is a water-soluble vitamin, which is needed by the body to form collagen
in bones, cartilage, muscle, and blood vessels, and which aids in the absorption of iron. Vitamin C is
an antioxidant. Antioxidants are substances that may protect your cells against the effects of free
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radicals. Free radicals are molecules produced when your body breaks down food, or by
environmental exposures like tobacco smoke and radiation. It helps to maintain healthy body
tissues and the immune system.
Vitamin C
- Chemical names (vitaminer) - ascorbic acid
- Deficiency may cause megaloblastic anemia
- Good sources include: fruit and vegetables. The Kakadu plum and the camu camu fruit have
the highest vitamin C contents of all foods. Liver also has vitamin C.
What is Choline?
Choline is a B vitamin-like molecule that is naturally produced by the human body. The body uses
choline to produce certain brain chemicals, to mobilize fat, for normal transmission of nerve
impulses, and is used for a range of body functions. A diet rich in lecithin food sources enables the
body to break this down into choline, or choline can be taken in supplement form. Studies show
that it may be an excellent memory tonic having positive effects on our thought processes and
mental well-being, as well as muscle control.
Nutritional Role of Choline
Choline is used by the brain to make acetylcholine, a neurotransmitter that plays a role in memory
function. It helps build cell membranes and move fats and nutrients between cells. Choline aids in
reproduction, fetal and infant development, a healthy liver, gallbladder, and heart. Choline
increases good cholesterol and reduces bad cholesterol.
Health Benefits of Choline in Human Nutrition
For memory and brain functions

For liver support and elimination of toxins (ie: hepatitis and cirrhosis)
For easing of heartburn
For good cholesterol levels
For gallstone prevention
For chemotherapy support related to liver function
For neural tube birth defects (spina bifida) prevention
For tics and twitches
For physical endurance and performance
Natural Sources of Choline
Eggs, soybeans, cabbage, peanuts, cauliflower, liver, oatmeal

What is Coenzyme Q10 (CoQ10)?
Overview
Coenzyme Q10 (CoQ10) is a substance thats found naturally in the body and helps convert food
into energy. CoQ10 is found in almost every cell in the body, and it is a powerful antioxidant.
Antioxidants fight damaging particles in the body known as free radicals, which damage cell
membranes, tamper with DNA, and even cause cell death. Scientists believe free radicals contribute
to the aging process, as well as a number of health problems, including heart disease and cancer.
Antioxidants, such as CoQ10, can neutralize free radicals and may reduce or even help prevent
some of the damage they cause.
Some researchers believe that CoQ10 may help with heart-related conditions, because it can
improve energy production in cells, prevent blood clot formation, and act as an antioxidant.
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Uses
Some studies suggest that coenzyme Q10 supplements, either by themselves or in with other drug
therapies, may help prevent or treat the following conditions:
After Heart Attack
One clinical study found that people who took daily CoQ10 supplements within 3 days of a heart
attack were less likely to have subsequent heart attacks and chest pain. They were also less likely to
die of heart disease than those who did not take the supplements. Anyone who has had a heart
attack should talk with their health care provider before taking any herbs or supplements,
including CoQ10.
Heart failure (HF)
Theres evidence that CoQ10 may help treat heart failure when combined with conventional
medications. People who have congestive heart failure, where the heart isnt able to pump blood as
well as it should may also have low levels of CoQ10. Heart failure can cause blood to pool in parts of
the body, such as the lungs and legs. It can also cause shortness of breath. Several clinical studies
suggests that CoQ10 supplements help reduce swelling in the legs; reduce fluid in the lungs, making
breathing easier; and increase exercise capacity in people with heart failure. But not all studies are
positive -- some find no effect -- so using CoQ10 for heart failure remains controversial. CoQ10
should never be used by itself to treat heart failure, and you should ask your health care provider
before taking it for this condition.
High blood pressure
Several clinical studies involving small numbers of people suggest that CoQ10 may lower blood
pressure. However, it may take 4 - 12 weeks to see any change. In one analysis, after reviewing 12
clinical studies, researchers concluded that CoQ10 has the potential to lower systolic blood
pressure by up to 17 mm Hg and diastolic blood pressure by 10 mm Hg, without significant side
effects. More research with greater numbers of people is needed. Dont try to treat high blood
pressure by yourself -- see your health care provider for treatment.
High cholesterol
People with high cholesterol tend to have lower levels of CoQ10, so CoQ10 has been proposed as a
treatment for high cholesterol, but so far theres no evidence whether it works or not. There is some
evidence it may reduce side effects from conventional treatment with cholesterol-lowering drugs
called statins, which reduce natural levels of CoQ10 in the body. Taking CoQ10 supplements can
bring levels back to normal. Plus, studies show that CoQ10 may decrease the muscle pain associated
with statin treatment. Ask your health care provider if you are interested in taking CoQ10 with
statins.
Diabetes
CoQ10 supplements may improve heart health and blood sugar and help manage high blood
pressure in people with diabetes. Two studies found that 100 mg of CoQ10 twice daily improved
A1c levels, a measure of long-term blood sugar control. But another study found no effect. If you
have diabetes, talk to your doctor or registered dietitian before using CoQ10.
Heart damage caused by chemotherapy
Several clinical studies suggest that CoQ10 may help prevent heart damage caused by certain
chemotherapy drugs, adriamycin, or other athracycline medications. More studies are needed,
however. Talk to your health care provider before taking any herbs or supplements if you are
undergoing chemotherapy.
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Heart surgery
Clinical research indicates that introducing CoQ10 prior to heart surgery, including bypass surgery
and heart transplantation, can reduce damage caused by free radicals, strengthen heart function,
and lower the incidence of irregular heart beat (arrhythmias) during the recovery phase. You
shouldnt take any supplements before surgery unless your health care provider approves.
Gum (Periodontal) disease
Gum disease is a common problem that causes swelling, bleeding, pain, and redness of the gums.
Clinical studies show that people with gum disease tend to have low levels of CoQ10 in their gums.
A few studies with small numbers of people found that CoQ10 supplements led to faster healing and
tissue repair, but the studies were not well designed. More research is needed.
Other
Preliminary clinical studies also suggest that CoQ10 may:
Improve immune function in people with HIV or AIDS

Increase sperm motility, improving male fertility
Be used as part of the treatment for Parkinson's disease
Improve exercise ability in people with angina
Help prevent migraines
Scientific studies are needed to see whether CoQ10 can be safely and effectively used for these
health problems and needs.
Dietary Sources
Primary dietary sources of CoQ10 include oily fish (such as salmon and tuna), organ meats (such as
liver), and whole grains. Most people get enough CoQ10 through a balanced diet, but supplements
may help people with particular health conditions (see "Uses" section) or those taking certain
medications (see "Interactions" section).
Supporting Research
Aguilaniu H, Durieux J, Dillin A. Metabolism, ubiquinone synthesis, and longevity. Genes Dev.
2005;19(20):2399-406.
Al-Hasso. Coenzyme Q10: a review. Hosp Pharm. 2001;36(1):51-66.
Beal MF. Therapeutic effects of coenzyme Q10 in neurodegenerative diseases. Methods Enzymol.
2004;382:473-87.
Belardinelli R, Mucaj A, Lacalaprice F, et al., Coenzyme Q10 and exercise training in chronic heart
failure. Eur Heart J. 2006;27(22):2675-81.
Berthold HK, Naini A, Di Mauro S, Hallikainen M, Gylling H, Krone W, Gouni-Berthold I. Effect of
ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: a randomised trial. Drug Saf.
2006;29(8):703-12.
Caso G, Kelly P, McNurlan MA, Lawson WE. Effect of coenzyme q10 on myopathyic symptoms in
patients treated with statins. Am J Cardiol. 2007;99(10):1409-12.
Dhanasekaran M, Ren J. The emerging role of coenzyme Q-10 in aging, neurodegeneration,
cardiovascular disease, cancer and diabetes mellitus. Curr Neurovasc Res. 2005;2(5):447-59.
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de Bustos F, Molina JA, Jimenez-Jimenz FJ, Garcia-Redondo A, Gomez-Escalonilla C, Porta-Etessam J,

et al. Serum levels of coenzyme Q10 in patients with Alzheimer's disease. J Neural Transm.
2000;107(2):233-239.
Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin.
Am J Health-System Pharm. 2000;57(13):1221-1227.
Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q(10) improves blood pressure and glycaemic
control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002;56:1137-1142.
Khan M, Gross J, Haupt H, et al., A pilot clinical trial of the effects of coenzyme Q10 on chronic
tinnitus aurium. Otolaryngol Head Neck Surg. 2007;136(1):72-7.
Khatta M, Alexander BS, Krichten CM, Fisher ML, Freudenberger R, Robinson SW et al. The effect of
conenzyme Q10 in patients with congestive heart failure. Ann Int Med. 2000;132(8):636-640.
Langsjoen PH, Langsjoen JO, Langsjoen AM, Lucas LA. Treatment of statin adverse effects with
supplemental Coenzyme Q10 and statin drug discontinuation. Biofactors. 2005;25(1-4):147-52.
Levy G, Kaufmann P, Buchsbaum R, et al., A two-stage design for a phase II clinical trial of coenzyme
Q10 in ALS. Neurology. 2006;66(5):660-3.
McCarty MF. Toward practical prevention of type 2 diabetes. Med Hypotheses. 2000;54(5):786-793.
Nahas R. Complementary and alternative medicine approaches to blood pressure reduction: An
evidence-based review. Can Fam Physician. 2008 Nov;54(11):1529-33. Review.
Ochiai A, Itagaki S, Kurokawa T, Kobayashi M, Hirano T, Iseki K. Improvement in intestinal
coenzyme q10 absorption by food intake. Yakugaku Zasshi. 2007;127(8):1251-4.
Ostrowski RP. Effect of coenzyme Q(10) on biochemical and morphological changes in experimental
ischemia in the rat brain. Brain Res Bull. 2000;53(4):399-407.
Palan PR, Connell K, Ramirez E, Inegbenijie C, Gavara RY, Ouseph JA, Mikhail MS. Effects of
menopause and hormone replacement therapy on serum levels of coenzyme Q10 and other lipidsoluble antioxidants. Biofactors. 2005;25(1-4):61-6.
Quinzii CM, Dimauro S, Hirano M. Human coenzyme q(10) deficiency. Neurochem Res. 2007;32(45):723-7.
Raitakari OT, McCredie RJ, Witting P, Griffiths KA, Letter J, Sullivan D, Stocker R, Celermajer DS.
Coenzyme Q improves LDL resistance to ex vivo oxidation but does not enhance endothelial
function in hypercholesterolemic young adults. Free Radic Biol Med. 2000;28(7):1100-1105.
Rakel D. Rakel: Integrative Medicine, 2nd ed. Philadelphia, PA. Elsevier Inc., 2007.
Rosenfeldt FL, Haas SJ, Krum H, Hadj A, Ng K, Leong JY, Watts GF. Conenzyme Q10 in the treatment
of hypertension: a meta-analysis of the clinical trials. J Hum Hypertens. 2007;21(4):297-306.
Rosenfeldt F, Hilton D, Pepe S, Krum H. Systematic review of effect of coenzyme Q10 in physical
exercise, hypertension and heart failure. Biofactors. 2003;18(1-4):91-100.
Salles JE, Moises VA, Almeida DR, Chacra AR, Moises RS. Myocardial dysfunction in mitochondrial
diabetes treated with Coenzyme Q10. Diabetes Res Clin Pract. 2006;72(1):100-3.
Sander S, Coleman CI, Patel AA, Kluger J, White CM. The impact of coenzyme Q10 on systolic
function in patients with chronic heart failure. J Card Fail. 2006;12(6):464-72.
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Shults CW, Haas R. Clinical trials of coenzyme Q10 in neurological disorders. Biofactors. 2005;25(14):117-26.
Shults CW. Therapeutic role of coenzyme Q(10) in Parkinson's disease. Pharmacol Ther.
2005;107(1):120-30.
Singh U, Devaraj S, Jialal I. Coenzyme Q10 supplementation and heart failure. Nutr Rev. 2007;65(6
Pt 1):286-93.
Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet. 1994;344:1372-1373.
Torkos S. Drug-nutrient interactions: A focus on cholesterol-lowering agents. Int J Integrative Med.
2000;2(3):9-13.
Watson PS, Scalia GM, Galbraith A, et al. Lack of effect of coenzyme Q on left ventricular function in
patients with congestive heart failure. J Am Coll Cardiol. 1999;33:1549-1552.
Weant KA, Smith KM. The role of coenzyme Q10 in heart failure. Ann Pharmacother.
2005;39(9):1522-6.
Witte KK, Clark AL, Cleland JG. Chronic heart failure and micronutrients. J Am Coll Cardiol.
2001;37(7):1765-1774.
What is Vitamin D?
Vitamin D is different from other essential vitamins because our own bodies can manufacture it
with sunlight exposure. The main function of vitamin D is to regulate the absorption of calcium and
phosphorus in our bones and aid in cell to cell communication throughout the body.
Frequent exposure of the skin to sunlight promotes sufficient vitamin D synthesis without the need
for supplements, however, adults who have darker skin pigmentation or frequently wear sun
protection during outdoor activities are often vitamin D deficient.
Vitamin D deficiency is extremely common in northern latitudes and is considered an epidemic in
the United States, according to a study published in the American Journal of Clinical Nutrition.1
What do we need vitamin D for?

According to the U.S. Department of Health and Human Services3, vitamin D is essential for the
"formation, growth, and repair of bones and for normal calcium absorption and immune function"
and there are studies to suggest that "higher levels of vitamin D in the blood are associated with
reduced risks of colorectal cancer; however, the research results overall have been inconsistent."
It is crucial for the absorption and metabolism of calcium and phosphorous, which have
various functions, especially the maintenance of healthy bones.
It is an immune system regulator.
Aids the immune system - vitamin D may be an important way to arm the immune system
against disorders like the common cold, say scientists from the University of Colorado
Denver School of Medicine, Massachusetts General Hospital and Children's Hospital Boston.
MS risk - it may reduce the risk of developing multiple sclerosis. Multiple sclerosis is much
less common the nearer you get to the tropics, where there is much more sunlight,
according to Dennis Bourdette, chairman of the Department of Neurology and director of
the Multiple Sclerosis and Neuroimmunology Center at Oregon Health and Science
University, USA.
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Maintaining cognitive functions - vitamin D may play a key role in helping the brain keep
working well in later life, according to a study of 3000 European men between the ages of
40 and 79.
Healthy body weight - vitamin D probably plays an important role in maintaining a healthy
body weight, according to research carried out at the Medical College of Georgia, USA.
Asthma symptoms and frequency - it can reduce the severity and frequency of asthma
symptoms, and also the likelihood of hospitalizations due to asthma, researchers from
Harvard Medical School found after monitoring 616 children in Costa Rica.
Rheumatoid arthritis - it has been shown to reduce the risk of developing rheumatoid
arthritis in women.
Protects from radiation damage - a form of vitamin D could be one of our body's main
protections against damage from low levels of radiation, say radiological experts from the
New York City Department of Health and Mental Hygiene.
Vitamin D and cancer risk - various studies have shown that people with adequate levels of
vitamin D have a significantly lower risk of developing cancer, compared to those whose
levels are low. Vitamin D deficiency was found to be prevalent in cancer patients regardless
of nutritional status in a study carried out by the Cancer Treatment Centers of America.
T.B. recovery - high vitamin D doses can help people recover from tuberculosis more
rapidly, researchers reported in September 2012 in the Proceeding of the National Academy
of Sciences (PNAS).
Heart attack risk - an study published in September 2012 suggested that low levels of
vitamin D may increase the risk of heart attack and early death.
Vitamin D deficiency
According to a study published in the American Journal of Clinical Nutrition10, "sensible sun
exposure (usually 5-10 minutes of exposure of the arms and legs or the hands, arms, and face, 2 or 3
times per week) and increased dietary and supplemental vitamin D intakes are reasonable
approaches to guarantee vitamin D sufficiency."
Alarming rates of Vitamin D deficiency in USA - data collected from the National Health and
Nutrition Examination Survey (NHANES), USA found that 9% (7.6 million) of children across the
USA were vitamin D deficient (defined as less than 15 ng/mL of blood), while another 61 percent,
or 50.8 million, were vitamin D insufficient (15 to 29 ng/mL).
Lead author of the study, Juhi Kumar, M.D., M.P.H, a fellow in pediatrics at Children's Hospital at
Montefiore Medical Center, The University Hospital and Academic Medical Center for Albert
Einstein College of Medicine, said: "We expected the prevalence of vitamin D deficiency would be
high, but the magnitude of the problem nationwide was shocking."
Recent developments on vitamin D deficiency from MNT news
Obesity can cause Vitamin D deficiency. Researchers from the D-CarDia collaboration associated a
high BMI with low Vitamin D levels, their findings were published in PLoS Medicine.
Vitamin D deficiency speeds up aging of bones. American and German scientists found that the
bones of people with vitamin D deficiency tend to age faster compared to those with healthy levels
of "the sunshine vitamin". The study was published in the journal Science Translational Medicine.
Vitamin D
- Chemical names (vitaminer) - ergocalciferol, cholecalciferol

- Fat soluble
- Deficiency may cause rickets, osteomalacia
- Good sources: produced in the skin after exposure to ultraviolet B light from the sun or
artificial sources. Also found in fatty fish, eggs, beef liver, and mushrooms.
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What is Vitamin E?
Vitamin E is a powerful, fat-soluble antioxidant that helps protect cell membranes against damage
caused by free radicals and prevents the oxidation of LDL cholesterol. Free radicals are compounds
formed when our bodies convert the food we eat into energy. People are also exposed to free
radicals in the environment from cigarette smoke, air pollution, and ultraviolet light from the sun.
The body also needs vitamin E to boost its immune system so that it can fight off invading bacteria
and viruses. It helps to widen blood vessels and keep blood from clotting within them. In addition,
cells use vitamin E to interact with each other and to carry out many important functions.
Vitamin E exists in eight different forms (isomers): alpha-, beta-, gamma-, and delta-tocopherol; and
alpha-, beta-, gamma-, and delta-tocotrienol. Alpha-tocopherol is the most active form in humans.
Dosing and daily allowance recommendations for vitamin E are often provided in alpha-tocopherol
equivalents (ATEs) to account for the different biological activities of the various forms of vitamin
E, or in international units (IU), which food and supplement labels may use. The conversion factor is
1mg of an ATE=1.5 IU.
Vitamin E supplements are available in natural or synthetic forms. The natural forms are usually
labeled with the letter "d" (for example, d-gamma-tocopherol), whereas synthetic forms are labeled
"dl" (for example, dl-alpha-tocopherol).
Why is vitamin E needed?
Vitamin E is needed for structural and functional maintenance of skeletal, cardiac, and smooth
muscle. It also assists in the formation of red blood cells and helps to maintain stores of vitamins A
and K, iron, and selenium. It may have a positive effect on immune health, protect against the
oxidative damage that can lead to heart disease, have preventive effects against cancer, help relieve
symptoms of Alzheimer's disease, and may help prevent some diabetes-related damage,
particularly to the eyes.
Vitamin E has been proposed for the prevention or treatment of numerous health conditions, often
based on its antioxidant properties. However, aside from the treatment of vitamin E deficiency,
there is a lack of clearly proven medicinal uses of vitamin E supplementation beyond the
recommended daily allowance. There is ongoing research on its use in numerous diseases,
particularly in cancer and heart disease.
What are the signs of a deficiency?
Vitamin E deficiency is very rare in healthy people. It is almost always linked to certain diseases
where fat is not properly digested or absorbed. Examples include Crohn's disease, cystic fibrosis,
and certain rare genetic diseases such as abetalipoproteinemia and ataxia with vitamin E deficiency
(AVED). Vitamin E needs some fat for the digestive system to absorb it.
Vitamin E deficiency can cause nerve and muscle damage that results in loss of feeling in the arms
and legs, loss of body movement control, muscle weakness, and vision problems. Another sign of
deficiency is a weakened immune system.
Vitamin E
- Chemical names (vitaminer) - tocopherols, tocotrienols

- Fat soluble
- Deficiency is uncommon. May cause mild hemolytic anemia in newborns
- Good sources include: kiwi fruit, almonds, avocado, eggs, milk, nuts, leafy green vegetables,
unheated vegetable oils, wheat germ, and whole grains.
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What is Vitamin K?
Vitamin K refers to two naturally occurring fat-soluble vitamins, vitamin K1 and vitamin K2.
Vitamin K1 is also known as phylloquinone or phytomenadione (phytonadione), while vitamin K2
includes menaquinone and menatetrenone.
Vitamin K1 is made by plants and Vitamin K2 is typically produced in the large intestine by bacteria.
Vitamins K3, K4 and K5 also exist - they are synthetic forms and are used to inhibit fungal growth as
well as by the pet food industry.
Vitamin K may very well be the next vitamin D as research continues to illuminate a growing
number of benefits to your health.
It is probably where vitamin D was ten years ago with respect to its appreciation as a vital nutrient
that has far more benefits than was originally recognized.
And, according to Dr. Cees Vermeer, one of the worlds top researchers in the field of vitamin K,
nearly everyone is deficient in vitamin K just like most are deficient in D.
Vitamin K measurements in blood plasma can be done accurately, but the results are not
necessarily helpful because they mainly reflect what you ate yesterday. Because of this, we will
have to trust Dr. Vermeer on his assessment that most are too deficient to reap all of its health
benefits. Vitamin K researchers across the world will acknowledge him as a leader in this field.
Most people get enough K from their diets to maintain adequate blood clotting, but NOT enough to
offer protection against the following health problemsand the list is growing:
Arterial calcification, cardiovascular disease and varicose veins

Osteoporosis
Prostate cancer, lung cancer, liver cancer and leukemia
Brain health problems, including dementia, the specifics of which are still being studied
Vitamin K comes in two forms, and it is important to understand the differences between them
before devising your nutritional plan of attack.
The Two Basic Types of Vitamin K

Vitamin K can be classified as either K1 or K2:
1. Vitamin K1: Found in green vegetables, K1 goes directly to your liver and helps you
maintain a healthy blood clotting system. (This is the kind of K that infants need to help
prevent a serious bleeding disorder.) It is also vitamin K1 that keeps your own blood
vessels from calcifying, and helps your bones retain calcium and develop the right
crystalline structure.
2. Vitamin K2: Bacteria produce this type of vitamin K. It is present in high quantities in your
gut, but unfortunately is not absorbed from there and passes out in your stool. K2 goes
straight to vessel walls, bones, and tissues other than your liver. It is present in fermented
foods, particularly cheese and the Japanese food natto, which is by far the richest source of
K2.
Vitamin K
- Chemical names (vitaminer) - phylloquinone, menaquinones

- Fat soluble
- Deficiency may cause bleeding diathesis
- Good sources which include: leafy green vegetables, avocado, kiwi fruit. Parsley contain a lot
of vitamin K.
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1.
2.
3.
4.
L. Bellows and R. Moore. "Fat-Soluble Vitamins: A, D, E, and K", Colorado State University
Extension. Accessed November 16th 2013.
"NCI Dictionary of Cancer Terms - water soluble vitamin", U.S. Department of Health and Human
Services, National Institutes of Health, National Cancer Institute, USA.gov. Accessed November
16th 2013.
"Vitamins", National Library of Medicine. Accessed November 16th 2013.
What every vegan should know about vitamin B12, The Vegan Society. Accessed November
17th 2013
What is Melatonin?
Melatonin is a natural hormone made by your body's pineal (pih-knee-uhl) gland. This is a peasized gland located just above the middle of the brain. During the day the pineal is inactive. When
the sun goes down and darkness occurs, the pineal is "turned on" by a special center called the
supra-chiasmatic nucleus (SCN).
A key factor in how humans sleep is regulated by exposure to light or to darkness. Exposure to light
stimulates a nerve pathway from the retina in the eye to an area in the brain called the hypothalamus. The SCN initiates signals to other parts of the brain that control hormones, body temperature
and other functions that play a role in making us feel sleepy or wide awake. SCN begins to actively
produce melatonin, which is released into the blood. Usually, this occurs around 9 pm. As a result,
melatonin levels in the blood rise sharply and you begin to feel less alert. Sleep becomes more
inviting. Melatonin levels in the blood stay elevated for about 12 hours - all through the night before the light of a new day when they fall back to low daytime levels by about 9 am. Daytime
levels of melatonin are barely detectable.
Besides adjusting the timing of the clock, bright light has another effect. It directly inhibits the
release of melatonin. That is why melatonin is sometimes called the "Dracula of hormones" - it only
comes out in the dark. Even if the pineal gland is switched "on" by the clock, it will not produce
melatonin unless the person is in a dimly lit environment. In addition to sunlight, artificial indoor
lighting can be bright enough to prevent the release of melatonin.
The amount of melatonin released at night varies among individuals, but it is somewhat related to
age. Children on average secrete more melatonin than adults, which decreases further with age.
However, research has shown that older people with sleep problems do not always have lower
melatonin levels than people who experience normal sleep.
begins to actively produce melatonin, which is released into the blood. Usually, this occurs around 9
pm. As a result, melatonin levels in the blood rise sharply and you begin to feel less alert. Sleep
becomes more inviting. Melatonin levels in the blood stay elevated for about 12 hours - all through
the night - before the light of a new day when they fall back to low daytime levels by about 9 am.
Daytime levels of melatonin are barely detectable.
Besides adjusting the timing of the clock, bright light has another effect. It directly inhibits the
release of melatonin. That is why melatonin is sometimes called the "Dracula of hormones" - it only
comes out in the dark. Even if the pineal gland is switched "on" by the clock, it will not produce
melatonin unless the person is in a dimly lit environment. In addition to sunlight, artificial indoor
lighting can be bright enough to prevent the release of melatonin.
The amount of melatonin released at night varies among individuals, but it is somewhat related to
age. Children on average secrete more melatonin than adults, which decreases further with age.
However, research has shown that older people with sleep problems do not always have lower
melatonin levels than people who experience normal sleep.
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What is Selenium?
Selenium is an essential mineral and micronutrient. It is fundamental to human health and found
in many foods. It is found in meat, seafood (hence, selenium levels are high in populations with
high intake of seafood, like the Inuit population),[1] grain cereals, egg yolk, milk, brazil nuts,
mushrooms and garlic.[2] Concern has been raised for some years about falling levels of selenium
intake and a possible relationship to the incidence of some diseases, including some cancers. [3]
Selenoproteins are important constituents of a number of enzymes with a range of functions
including antioxidant function, thyroid hormone metabolism, male fertility and immune
mechanisms. A decline in blood selenium levels in countries has raised concern about possible
public health implications, particularly in relation to cancer and cardiovascular disease.[3] [4]
How much selenium is recommended?
Dietary recommendations for selenium differ between countries. This is because there is
uncertainty over what constitutes 'optimal selenium status'.[5] The average daily intake of selenium
in the UK has been falling over a 30-year period.[5]
The recommended daily allowance (RDA) in the US RDA is 55 micrograms/day for adults. The
World Health Organization (WHO) RDA for selenium is 70 micrograms/day to 350
micrograms/day. Some are recommending supranutritional supplements of 200 micrograms/day
to 800 micrograms/day. Toxic effects probably occur at around 40 x the RDA.
How are selenium levels measured?
Erythrocyte, serum and tissue levels of glutathione peroxidase (GP) can be measured to assess
selenium status. Selenium in hair and nails can also be measured. Discuss with your laboratory
before deciding which method to use.
Why is selenium essential?
Dietary recommendations were made over 15 years ago on the basis of blood levels of glutathione
peroxidase (GP). This intracellular enzyme converts hydroxyl radicals or hydrogen peroxide into
water and this requires selenium as a cofactor. Levels of this enzyme have thus been taken to
correlate with selenium levels. Since then, over 30 new selenoproteins have been identified and
about half of these have an identified biological function.[2] These selenoproteins include:
Four GP enzymes, a major class of functionally important selenoproteins and the first to be
characterized:
Classical GP x 1.
Gastrointestinal GP x 2.
Plasma GP x 3.
Phospholipid hydroperoxide GP x 4.
Thioredoxin reductase (TR), a selenocysteine-containing enzyme important in regulating
metabolic activity.
Selenoprotein P (60% of plasma selenium is held in this form) may have a role in the
transport of selenium but also may have other functions.
Several iodothyronine deiodinase enzymes. These are responsible for conversion of the
prohormone thyroxine to the active thyroid hormones (triiodothyronine, or T3).
Sperm capsule selenoprotein which may be responsible for maintaining integrity of the
sperm flagella (and hence motility of sperm).
Selenoprotein W. This is involved in muscle metabolism.
What harm does deficiency of selenium cause?

Deficiency of selenium may cause a variety of problems, but the health implications of a decline in
selenium levels in the UK for example over the 25 years have not been systematically
investigated.[2] In general, selenium is thought to be important in a number of varied aspects of
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health (for a healthy immune system, for a protective effect against some forms of cancer, to
maintain and enhance male fertility, for a reduction in cardiovascular mortality and to regulate
inflammatory markers in asthma). Research is in progress and there is a lot of interest in the results
of this research. Although there are still many unanswered questions, so far selenium has been
linked with:
Keshan disease and Kashin-Beck disease (also often referred to as Keshan-Beck disease).
These are both associated with selenium deficiency.[6][7][8]
Counteracting the development of virulence and inhibiting HIV progression to AIDS.[9] Trials
are small and results mixed but more research is called for.[10][11]
Enhancing sperm motility. Selenium-deficient rats have immotile deformed sperm and
infertility. Although there is a rationale for this[12] one RCT was not able to show such an
effect.[13]
A possible role in preventing pre-eclampsia, although the Cochrane review suggests more
trials are necessary.
A possible relationship between mood disturbance and selenium deficiency.
A possible association between elevated selenium intake and reduced cancer risk. The
association between selenium status and cancer risk remains enigmatic and
epidemiological studies have failed to consistently link low selenium levels with increased
cancer risk in men and women.[14] It is possible that there may be gender differences in
susceptibility to cancer risk with men being more susceptible to the risk of low selenium. [14]
In the Nutritional Prevention of Cancer Trial, daily supplementation of selenium
significantly reduced prostate cancer in men.[15][16] It is thought that the greatest benefit
from selenium supplementation will be in low selenium status populations, although the
biggest primary and secondary prevention trials - SELECT (=Selenium and Vitamin E C
ancer Prevention Trials) - are underway in the USA (where selenium status is good).[17]
Some were predicting that the SELECT trial results in 2013 would show benefit. [18]
However, this trial was recently discontinued because there was no evidence of a benefit
from either vitamin E or selenium on prevention of prostate cancer.[19] Concern was also
raised about a link between selenium supplementation and an increased risk of developing
7type 2 diabetes.[20]
In asthma, some epidemiological studies suggest that deficiencies of selenium, zinc and
other nutrients (vitamins A, C, D, and E) may be associated with the development of allergic
disorders and asthma.[21] Although a number of trials suggest supplementation with
selenium may help symptoms of chronic asthma, only one small trial, according to the
Cochrane review, showed evidence of this.
Cardiovascular disease. Deficiency is associated with cardiomyopathy.[22] The hypotheses
that low selenium concentrations are associated with increased cardiovascular disease and
that selenium supplements prevent coronary heart disease are unproven. Selenium
supplementation cannot currently be recommended for cardiovascular disease
prevention.[23]
Deficiency in trauma and burns patients. One study reports improved recovery with
selenium supplementation in trauma and burns patients.[24]
The thyroid gland is rich in selenium. Selenium deficiency may help to precipitate
hypothyroidism and autoimmune thyroid disease and supplementation may contribute to
prevention of these diseases.[25]
Who is at risk of selenium deficiency?

Risk factors include:
Poor dietary intake.

Smoking. Smokers have lower levels of selenium compared with non-smokers.[26]
Socio-economic status. Lower levels have been found in people receiving state benefits or
with lower educational attainment.[26]
The elderly living in residential or nursing homes had lower levels of selenium [26] as did
elderly hospital patients[27] when compared with 'free-living' elderly patients.
The elderly, particularly in areas where low intake is common.
Where you live:
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Areas with a low selenium soil environment are associated with deficiency. Such
areas include parts of China, Croatia,[28] New Zealand,[29][30] the Slovak Republic.[31]
The elderly in such areas are particularly at risk and one study from New Zealand
recently demonstrated suboptimal levels of selenium in a significant proportion of
103 elderly New Zealand women.[ 29]
The levels of selenium are higher in the south of England than in the north.[ 26] The
selenium status may vary within countries according to factors such as the selenium
in the local soil but is also affected by the levels of selenium in imported crops.
Patients on total parenteral nutrition (TPN).[32][33][34]
Trauma and burns patients.[ 24]
Vegetarians in countries with low selenium status.[35]
Indications for supplementation

Those at high risk of deficiency should have their selenium status measured. If deficient in
selenium, such patients should certainly be given supplements. As with many nutritional
components, distinction must be drawn between the basic nutritional requirement to prevent
deficiency and supplementation to prevent, for example, chronic disease and cancer.[36][37][38]
Further reading & references

1. Hansen JC, Deutch B, Pedersen HS; Selenium status in Greenland Inuit. Sci Total Environ.
2004 Sep 20;331(1-3):207-14.
2. Brown KM, Arthur JR; Selenium, selenoproteins and human health: a review. Public Health
Nutr. 2001 Apr;4(2B):593-9.
3. Rayman MP; Dietary selenium: time to act. BMJ. 1997 Feb 8;314(7078):387-8.
4. Rayman MP; The importance of selenium to human health. Lancet. 2000 Jul
15;356(9225):233-41.
5. Hurst R, Armah CN, Dainty JR, et al; Establishing optimal selenium status: results of a
randomized, double-blind, Am J Clin Nutr. 2010 Apr;91(4):923-31. Epub 2010 Feb 24.
6. Peng A, Yang C, Rui H, et al; Study on the pathogenic factors of Kashin-Beck disease. J
Toxicol Environ Health. 1992 Feb;35(2):79-90.
7. Zhang WH, Neve J, Xu JP, et al; Selenium, iodine and fungal contamination in Yulin District
(People's Republic of China) endemic for Kashin-Beck disease. Int Orthop. 2001;25(3):18890.
8. Fang W, Wu P, Hu R, et al; Environmental Se-Mo-B deficiency and its possible effects on
crops and Keshan-Beck disease (KBD) in the Chousang area, Yao County, Shaanxi Province,
China. Environ Geochem Health. 2003 Jun;25(2):267-80.
9. Kupka R, Msamanga GI, Spiegelman D, et al; Selenium status is associated with accelerated
HIV disease progression among HIV-1-infected pregnant women in Tanzania. J Nutr. 2004
Oct;134(10):2556-60.
10. Kaiser JD, Campa AM, Ondercin JP, et al; Micronutrient supplementation increases CD4
count in HIV-infected individuals on highly active antiretroviral therapy: a prospective,
double-blinded, placebo-controlled trial. J Acquir Immune Defic Syndr. 2006 Aug
15;42(5):523-8.
11. Irlam JH, Visser MM, Rollins NN, et al; Micronutrient supplementation in children and adults
with HIV infection. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD003650.
12. Foresta C, Flohe L, Garolla A, et al; Male fertility is linked to the selenoprotein phospholipid
hydroperoxide glutathione peroxidase. Biol Reprod. 2002 Sep;67(3):967-71.
13. Hawkes WC, Turek PJ; Effects of dietary selenium on sperm motility in healthy men. J
Androl. 2001 Sep-Oct;22(5):764-72.
14. Waters DJ, Chiang EC, Cooley DM, et al; Making sense of sex and supplements: differences in
the anticarcinogenic effects of selenium in men and women. Mutat Res. 2004 Jul 13;551(12):91-107.
15. Waters DJ, Shen S, Glickman LT, et al; Prostate cancer risk and DNA damage: translational
significance of selenium supplementation in a canine model. Carcinogenesis. 2005
Jul;26(7):1256-62. Epub 2005 Apr 7.
16. Meyer F, Galan P, Douville P, et al; Antioxidant vitamin and mineral supplementation and
prostate cancer prevention in the SU.VI.MAX trial. Int J Cancer. 2005 Aug 20;116(2):182-6.
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17. Rayman MP; Selenium in cancer prevention: a review of the evidence and mechanism of
action. Proc Nutr Soc. 2005 Nov;64(4):527-42.
18. Drake EN; Cancer chemoprevention: selenium as a prooxidant, not an antioxidant. Med
Hypotheses. 2006;67(2):318-22. Epub 2006 Mar 30.
19. Schmid HP, Fischer C, Engeler DS, et al; Nutritional aspects of primary prostate cancer
prevention. Recent Results Cancer Res. 2011;188:101-7.
20. Muecke R, Schomburg L, Buentzel J, et al; Selenium or no selenium--that is the question in
tumor patients: a new Integr Cancer Ther. 2010 Jun;9(2):136-41. Epub 2010 May 11.
21. Nurmatov U, Devereux G, Sheikh A; Nutrients and foods for the primary prevention of
asthma and allergy: Systematic J Allergy Clin Immunol. 2011 Mar;127(3):724-733.e30. Epub
2010 Dec 24.
22. Kanekura T, Yotsumoto S, Maeno N, et al; Selenium deficiency: report of a case. Clin Exp
Dermatol. 2005 Jul;30(4):346-8.
23. Flores-Mateo G, Navas-Acien A, Pastor-Barriuso R, et al; Selenium and coronary heart
disease: a meta-analysis. Am J Clin Nutr. 2006 Oct;84(4):762-73.
24. Berger MM; Antioxidant micronutrients in major trauma and burns: evidence and practice.
Nutr Clin Pract. 2006 Oct;21(5):438-49.
25. Duntas LH; Selenium and the thyroid: a close-knit connection. J Clin Endocrinol Metab. 2010
Dec;95(12):5180-8. Epub 2010 Sep 1.
26. Bates CJ, Thane CW, Prentice A, et al; Selenium status and its correlates in a British national
diet and nutrition survey: people aged 65 years and over. J Trace Elem Med Biol.
2002;16(1):1-8.
27. Schmuck A, Roussel AM, Arnaud J, et al; Analyzed dietary intakes, plasma concentrations of
zinc, copper, and selenium, and related antioxidant enzyme activities in hospitalized elderly
women. J Am Coll Nutr. 1996 Oct;15(5):462-8.
28. Dodig S, Cepelak I; The facts and controversies about selenium. Acta Pharm. 2004
Dec;54(4):261-76.
29. de Jong N, Gibson RS, Thomson CD, et al; Selenium and zinc status are suboptimal in a
sample of older New Zealand women in a community-based study. J Nutr. 2001
Oct;131(10):2677-84.
30. Sheck L, Davies J, Wilson G; Selenium and ocular health in New Zealand. N Z Med J. 2010 Jun
11;123(1316):85-94.
31. Madaric A, Kadrabova J, Ginter E; Selenium concentration in plasma and erythrocytes in a
healthy Slovak population. J Trace Elem Electrolytes Health Dis. 1994 Mar;8(1):43-7.
32. Ishida T, Himeno K, Torigoe Y, et al; Selenium deficiency in a patient with Crohn's disease
receiving long-term total parenteral nutrition. Intern Med. 2003 Feb;42(2):154-7.
33. Yusuf SW, Rehman Q, Casscells W; Cardiomyopathy in association with selenium deficiency:
a case report. JPEN J Parenter Enteral Nutr. 2002 Jan-Feb;26(1):63-6.
34. Alfieri MA, Leung FY, Grace DM; Selenium and zinc levels in surgical patients receiving total
parenteral nutrition. Biol Trace Elem Res. 1998 Jan;61(1):33-9.
35. Kadrabova J, Madaric A, Kovacikova Z, et al; Selenium status, plasma zinc, copper, and
magnesium in vegetarians. Biol Trace Elem Res. 1995 Oct;50(1):13-24.
36. Combs GF Jr; Impact of selenium and cancer-prevention findings on the nutrition-health
paradigm. Nutr Cancer. 2001;40(1):6-11.
37. Rayman MP, Rayman MP; The argument for increasing selenium intake. Proc Nutr Soc. 2002
May;61(2):203-15.
38. Ryan-Harshman M, Aldoori W; The relevance of selenium to immunity, cancer, and
infectious/inflammatory diseases. Can J Diet Pract Res. 2005 Summer;66(2):98-102.
Disclaimer: This article is for informational purposes only and should not be used for the diagnosis
or treatment of medical conditions. Spray For Life has used all reasonable care in compiling the
information but make no warranty as to its accuracy. Consult a doctor or other health care
professional for diagnosis and treatment of medical conditions.
Original Author: Dr. Richard Draper
Sprayforlife.com
What is Zinc?
Zinc: Essential for Human Health
Zinc is an essential trace element for humans, animals and plants. It is vital for many biological
functions and plays a crucial role in more than 300 enzymes in the human body. The adult body
contains about 2-3 grams of zinc. Zinc is found in all parts of the body: it is in organs, tissues, bones,
fluids and cells. Muscles and bones contain most of the bodys zinc (90%). Particularly high
concentrations of zinc are in the prostate gland and semen.
Zinc - vital for growth and cell division
Zinc is especially important during pregnancy, for the growing fetus whose cells are rapidly
dividing. Zinc also helps to avoid congenital abnormalities and pre-term delivery. Zinc is vital in
activating growth - height, weight and bone development - in infants, children and teenagers.
Zincvital for fertility
Zinc plays a vital role in fertility. In males, zinc protects the prostate gland from infection
(prostates) and ultimately from enlargement (prostatic hypertrophy). Zinc helps maintain
sperm
count
and
mobility
and
normal
levels
of
serum
testosterone.
In females, zinc can help treat menstrual problems and alleviate symptoms associated with
premenstrual syndrome (PMS).
Zincvital for the immune system
Among all the vitamins and minerals, zinc shows the strongest effect on our all-important immune
system. Zinc plays a unique role in the T-cells. Low zinc levels lead to reduced and weakened T-cells
which are not able to recognize and fight off certain infections. An increase of the zinc level has
proven effective in fighting pneumonia and diarrhea and other infections. Zinc can also reduce the
duration and severity of a common cold.
Zinc vital for taste, smell and appetite
Zinc activates areas of the brain that receive and process information from taste and smell sensors.
Levels of zinc in plasma and zincs effect on other nutrients, like copper and manganese, influence
appetite and taste preference. Zinc is also used in the treatment of anorexia.
Zincvital for skin, hair and nails
Zinc accelerates the renewal of the skin cells. Zinc creams are used for babies to soothe diaper rash
and to heal cuts and wounds. Zinc has also proven effective in treating acne, a problem that affects
especially adolescents, and zinc has been reported to have a positive effect on psoriasis and
neurodermitis.
Zinc is also used as an anti-inflammatory agent and can help sooth the skin tissue,
particularly in cases of poison ivy, sunburn, blisters and certain gum diseases.
Zinc is important for healthy hair. Insufficient zinc levels may result in loss of hair, hair that looks
thin and dull and that goes grey early. There are also a number of shampoos which contain zinc to
help prevent dandruff.
Zinc vital for vision
High concentrations of zinc are found in the retina. With age the retinal zinc declines which seems
to play a role in the development of age-related macular degeneration (AMD), which leads to partial
or complete loss of vision. Zinc may also protect from night blindness and prevent the development
of cataracts.
Who needs zinc?
Everyone needs zinc. Children need zinc to grow, adults need zinc for health. Growing infants,
children and adolescents, pregnant women and lactating mothers, athletes, vegetarians and the
elderly often require more zinc.
Where do we get zinc from?
We get zinc primarily from our food. The major sources of zinc are (red) meat, poultry, fish and
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seafood, whole cereals and dairy products. Zinc is most available to the body from meat. The
bioavailability of plant-based foods is generally lower due to dietary fibre and phytic acid which
inhibit the absorption of zinc.
A balanced diet is the best way to provide your body with zinc. A zinc supplement or a daily multivitamin/multi-mineral supplement may be taken if your nutritional intake is insufficient.*
What if we dont get enough zinc?
Zinc deficiency is a serious problem in many developing countries. Zinc deficiency is ranked as the
5th leading risk factor in causing disease, especially diarrhea and pneumonia in children, which can
lead to high mortality rates in these underdeveloped regions. Other severe deficiency symptoms
include stunted growth and impaired development of infants, children and adolescents. Early zinc
deficiency also leads to impaired cognitive function, behavioral problems, memory impairment and
problems with spatial learning and neuronal atrophy. Public health programs involving zinc
supplementation and food fortification could help overcome these problems.
All information furnished by The International Zinc Association

Order and Payment
Q1: How do I place an order?
A: To place an order using your shopping cart, follow these simple steps:
1. Add items to your cart by clicking the Add to Cart button displayed along with the product
description.
2. When you have added all of the items you wish to purchase to your cart, click the Checkout
button on either the shopping cart page or the top right corner of the page you are using.
3. Enter your billing, shipping and payment information as directed.
4. Confirm your order by clicking the SUBMIT ORDER button located at the bottom of the
confirmation page.
Q2: A product I wish to buy is out of stock. Can I still order it?
A: For shipments in the continental United States: If an item is backordered, we will ship the
balance of your order immediately and send your backordered item when it becomes available at
no additional shipping charge.
For shipments elsewhere outside of the United States: If an item is backordered, we will give
you the option of holding your shipment until it is complete or eliminating the backordered product
from your order.
Q3: How can I find out the status of my order?

A: Ensure you have received a shipping confirmation email and locate tracking number.
Q4: Can customers outside the U.S. order from the website?
A: Yes. The order and payment methods for international orders are the same as for domestic orders.
Q5: Can I make changes to my order after I have submitted it?
A: We work hard to get your orders processed as quickly as possible. Due to the speed of most of our
shipments, they are usually processed and shipped the same day so we are not able to make any
changes once the order has been submitted.
Sprayforlife.com
Q6: Can I cancel my order once it has been submitted?

A: We work hard to get your orders processed as quickly as possible. Due to the speed of most of our
shipments, they are usually processed and shipped the same day so we are not able to make any
changes once the order has been submitted.
Q7: I order the same products each time. Can I be set up to receive them automatically?
A: We currently have an auto ship program that allows you to have your Spray For Life products sent
to you monthly with free shipping. For details on Auto Ship please click HERE.
Q8: Will you notify me if there are problems with my order?

A: We will immediately notify you by email of any complications with your order, including
backorders and credit card authorization issues.
Q9: What forms of payment do you accept?

A: We accept the following credit cards:
Visa
MasterCard
American Express
Discover
And also for your convenience, we accept PayPal
Q10: Do I need to pay sales tax with my order?

A: No. All Spray For Life products are considered as food and are exempt.
Q11: If one or more of my items are on backorder, when will I receive my order?
A: If any items are on backorder, we may hold the order for a few days to wait for the backordered
items if they will be back in stock soon. If we don't expect the backordered item back in stock within
a few days, we will ship the rest of your order as scheduled.
Shipping
Q1: When will my order ship?
A: We make every effort to ship your order the same day if it is placed before 5p.m. Eastern Time and
if all items are in stock. If any items are on backorder, we may hold the order for a few days to wait
for the backordered items if they will be back in stock soon.
Q2: What shipping carrier do you use?

A: United States Postal Service
Q3: What are my shipping options? How much does each cost, and how long will it take?
A: All orders shipped within the United States, U.S. Territories (Puerto Rico, U.S. Virgin Islands, Guam,
American Samoa, Palau, and the Northern Mariana Islands) P.O. Boxes, APO, FPO or DPO addresses
are shipped for a flat shipping fee of $4.95. When you place your order on the web, the shipping
option will automatically default to the $4.95 (standard) option. If your address qualifies for other
shipping options, you will be able to select the option of your choice. Shipping options that you may
qualify for include:
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Standard (2-7 Business days) $4.95

Priority (1-3 business days) $7.95
Express (Next Day) $19.95
Q4: Do you refrigerate products during shipping?

A: Products are kept under a temperature controlled environment in our warehouse facility, but are
not kept refrigerated during the course of shipping. Please refer to Q30: Is Spray For Life affected
by extreme temperatures, for additional information
Q5: How can I determine the exact shipping cost for international orders?
A: International Shipping cost can only be obtained at the checkout page. If you do not agree with the
cost you may back out of your order.
Q6: Will you notify me when my order has been shipped?

A: You will first receive an email confirming your order, and then another email notifying you when
your order has been shipped.
Q7: Can I ship to an address other than my own?

A: Yes. When you go through the order checkout process, you will be able to enter separate addresses
for billing and shipping.
Return Policy
Q1: What is your Easy Return Policy?
A: Our Easy Return Policy: NanoSynergy Worldwide takes great pride in manufacturing a superior
nutritional product for our customers and is backing it up with a 100% Satisfaction Guarantee. If for
any reason you're unsatisfied with your purchase, you may return the product for a full refund.
Q2: How do I return an item?

A: To make a return, you must first request a Return Merchandise Authorization (RMA) number.
Before you send your merchandise back to NanoSynergy, request your RMA number by emailing
your request to returns@nanosynergyww.com.
Please write your RMA number on the outside of your package for returns via mail, you must
carefully package the product, you are responsible for the cost of return shipping, and we must
physically receive the return within the 30 day period. We recommend using UPS, FedEx or some
other form of insured mail for returns, as we cannot be responsible for items that never make it
back to our warehouse.
NanoSynergy reserves the right, at its sole discretion, to reject any return that does not
comply with these requirements.
Q3: What should I do if my items arrive damaged or defective?

A: We make every effort to package your order so that it will arrive in great condition. Unfortunately,
sometimes items may be damaged during shipment. We understand your frustration and we will do
everything we can to replace the product as quickly as possible. If you have received a damaged
item, please e-mail us at customercare@nanosynergyww.com or call us at 1-877- NSW-NANO (6796266). Give us your name, order number and the item number that was damaged and we will
arrange for the damaged item to be replaced immediately.
Sprayforlife.com
Q4: What should I do if I received the wrong item?

A: If you received the wrong product, simply e-mail us at customercare@nanosynergyww.com or call
us at 1-877- NSW-NANO (679-6266). Give us your name, order number and the item that was not
correct and what item you should have received. We will check into this immediately, arrange for
the missing product to be returned to us, and send out the correct product right away! You will
receive the correct one before you know it.
Privacy Policy and Terms & Conditions
Welcome to Spray For Life , owned by NanoSynergy Worldwide, Inc. If you have any questions
about our policies and procedures you may feel free to contact us at Spray For Life Contact
attention Privacy Department.
Spray For Life has created the following privacy policy to fulfill our commitment to protecting
your privacy, and to inform you of our information-gathering and dissemination practices. This
online privacy policy will tell you about, among other things, the information Spray For Life
collects through our Web site, how we use that information, how you can opt out of certain uses of
the information we collect, and how Spray For Life can make changes to this privacy policy.
Please let us know if you have any questions regarding this privacy policy by contacting us at
info@sprayforlife.com.
But first a note about children's privacy...
We do not knowingly collect personal information from children under the age of 13. If we learn
that we have inadvertently obtained personal information on a child under the age of 13, that
information will be deleted from our systems. Spray For Life encourages parents to go online with
their kids. Here are a few tips to help make a child's online experience safer:
Teach kids never to give out personal information, unless supervised by a parent or responsible
adult. This includes their name, address, phone, school, etc.
Know the sites your kids are visiting and which sites are appropriate.
Look for Web site privacy policies. Know how your child's information is being treated.
Q1: What information does Spray For Life collect?

A: Our purpose in collecting your personal information is to provide you with a more customized
experience. This information lets us provide services and features that we think are more likely to
meet your needs. Of course, users can browse our Web site without providing any personal
information, but once you give us this personal information, you are not anonymous to us.
Spray For Life collects two types of information when you visit our Web site: information that
may be used to identify you individually, such as your name and email address ("personal
information"), and non-personal information, such as IP addresses, the type of browser you are
using, and aggregated information about user activities on our Web site ("non-personal
information").
Personal Information: We specifically request personal information from you at certain points on
our Web site. For example, when you purchase product through our web site and enroll in any of
our forums, we collect personal information to complete the transaction. This information may
include, without limitation, your name, shipping and billing addresses, telephone number, email
address, and credit card information. From time to time, we may also request personal information
Sprayforlife.com
about you and your interests in surveys, contest entry forms, or in other ways. You may always
choose not to provide us with your personal information; however, this may limit our ability to
provide you with a specific product or service, or to offer you personalized content.
Non-Personal Information: When you visit our Web site, we also collect non-personal
information, such as your IP address, which is a number that can be used to identify your location
and Internet Service Provider. We may also collect the URL from which you came to our Web site
and the URLs visited on our Web site. A URL is the full address of a Web site page, which may
contain some personal or identifying information about the person who is viewing it.
Use of Cookies: We also use a feature of your browser called a cookie to assign identification to
your computer. The unique user ID contained within your cookie automatically identifies your
computerbut not youto our servers every time you visit our Web site. Cookies by themselves
cannot be used to find out the identity of any user, but may be correlated with identity information
in our log files. You can turn off the cookie feature by using your browser preference options, but
you may not be able to utilize some services properly. Current versions of many Web browsers
offer enhanced user controls for the placement and duration of cookies. Search for "cookies" under
your Web browser's Help menu for more information on the cookie management features available
to you.
Use of Pixel Tags: We may also collect information through the use of "pixel tags" included in email
messages we may send to you. Pixel tags are tiny graphic files, not visible to the human eye, that are
included in HTML-encoded email messages. When such a message is opened in an HTML-capable
email program, the recipient's computer will access our server to retrieve the pixel tag file, allowing
us to record and store, along with the recipient's email address, the date and time the recipient
viewed the email message, the fact that the recipient's email program is capable of receiving HTMLencoded email, and other standard logging information. The pixel tag also may see or read cookies.
Q2: How does Spray For Life use or disclose the information it collects?
A: Spray For Life's Use of Personal Information and Non-Personal Information: We use your personal
information to process your requests, to improve the features of our Web site, and to communicate
with you. We may also use your personal information to personalize our Web site, to target
advertising or promotions that may be of interest to you, and to analyze aggregate user data in
order to improve our services. On occasion, we may also contact you about Spray For Life
products or services that we think you will find useful. We might also contact you to see if you are
interested in participating in market research regarding Spray For Life. For information about
opting out of such communications, please see our Opt-Out Policy section below.
Co-Branded Offers: In arranging to have marketing and promotional information of certain
companies or businesses with whom Spray For Life may have formed a strategic alliance
("Affiliated Companies"), we may disclose to the Affiliated Companies your personal information,
including information such as your shipping address, billing information, telephone number, and
credit card information. If you do not want us to disclose your personal information to the Affiliated
Companies, please refer to the Opt-Out Policy below.
Third-Party Offers: In arranging to have marketing and promotional information of third-party
companies that we think might be of interest to you, we may disclose your personal information,
including information such as your shipping address, billing information, telephone number, and
credit card information to nonaffiliated third parties not controlled by Spray For Life . If you do
not want to us to disclose your personal information to third-party companies, please refer to the
Opt-Out Policy below.
Cookies (again): We may use cookie and IP address information to count and track Web site visits
in the aggregate, to personalize the Web site for each unique user, to control the frequency of
individual advertisements to individual computers, and to target advertisements and promotions to
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broad demographic segments. We may also use IP addresses to help diagnose problems with our
server, and to administer our Web site.
Customer Service Issues and Contacts: We may use your email address to contact you in
response to customer service complaints you have submitted, to address a problem affecting your
use of the service, or to verify information concerning a transaction.
Transaction Processing: When you make a purchase on our Web site, we may need to provide
personal information, including information such as your shipping address, billing information,
telephone number, and credit card information, to third parties, including product manufacturers
and shipping companies, as necessary solely to complete the transaction.
Legal Requirements: We may disclose personal information when we deem necessary or
appropriate to law enforcement or other entities or third parties as required by law or to protect
our rights or the rights of others, to prevent harm to persons or property, to fight fraud, identity
theft, or otherwise to comply with the law or legal process, to respond to claims, to protect our
systems and customers, to ensure the integrity and operation of our business and systems, or to
protect the rights, property, or safety of Spray For Life and its employees or others.
Business and Accounting Disclosures: We may also disclose non-identifying transaction
information to third parties for the purpose of accounting and record keeping. We may also disclose
aggregate user data or non-personal information in order to describe our services to prospective
business partners, advertisers, and others, but will do so only in a form that does not identify
individual users.
Opt-Out Policy
You may opt out of receiving communication from us, from Affiliated Companies, or from other
third parties by emailing us at: info@sprayforlife.com or Spray For Life Contact.
Also, when we contact you via email, we may include instructions to unsubscribe from future
emails if you so choose.
Security
This Web site has industry-standard security measures in place to protect the loss, misuse, and
alteration of the information under our control, and we make good-faith efforts to store your
personal information in a secure operating environment. Unfortunately, no data transmission over
the Internet can be guaranteed to be absolutely secure. As a result, while we strive to protect your
personal information, we cannot ensure or warrant the security of any information you transmit to
us or our online products or services, and you do so at your own risk.
Other Websites; Links

We may include links to Web sites operated by our business partners, affiliates, advertisers, and
others. These third parties have separate data collection and privacy practices independent from
ours, and thus Spray For Life cannot be responsible for their policies or activities. Please contact
those third parties directly if you have questions about their privacy policies.
Community Center/Community Chat rooms/Message Boards

If our Web site includes online forums, chat rooms, message boards, and other interactive
technologies that allow comments, messages, emails, and postings to be associated with a user's
Sprayforlife.com
name or email address. Any information you post is public information and Spray For Life cannot
control what use third parties may make of this personal information.
All of these forums are public. Please consider this before you post.
Q3: How can I correct, update, or delete my information?

A: Spray For Life does not currently have a method for users to delete the personal information
contained in our database. However, you may change or update the personal information we have
collected by sending an email to info@sprayforlife.com. Please include your email address, your
order number, the name of the product you purchased, and the information you wish to change. In
addition, you may delete the cookie stored on your computer, which will cause our system to
perceive you as a new user with no known user data. You may also set your browser to reject
cookies, but doing so may prevent you from using some of our services.
International Users
Like almost every Web site, Spray For Life may be accessed by an international audience. By
visiting our Web site and providing us with data, you acknowledge and agree that your personal
information may be processed for the purposes identified in this policy. In addition, such data may
be stored on servers located outside your resident jurisdiction and in jurisdictions which may have
less stringent privacy practices than your own. By providing us with your data, you consent to the
transfer of such data.
Q4: What happens to my information if Spray For Life is sold to or merges

with another company?
A: It is possible that Spray For Life and/or any of our assets may be acquired by an unrelated third
party. In such a transaction, as the owner of this customer information, we may disclose or sell the
information as an asset of the company in conjunction with the sale of our company or the sale of a
portion of our assets to a third party. While we will endeavor to require the successor company to
maintain this privacy policy, we cannot guarantee that our policy will remain in effect.
Changes to This Policy

This policy may change from time to time. If we make any substantive changes to the policy in the
future with regard to how we use your information, we will post those changes on our Web site in
this location together with the date of the last update. Your continued use of the Web site after the
changes are posted constitutes your agreement to the changes, both with regard to information we
have previously collected from you and with regard to information we collect from you in the
future. If you do not agree to the changes, please discontinue your use of our Web site.
Last changed: 1/1/2016
Contacting Spray For Life

Please feel free to share any comments and concerns with us. If you have any questions about this
privacy policy or the practices of this Web site, please contact:
Spray For Life Contact or email us: info@sprayforlife.com
Sprayforlife.com
GENERAL INFO
General Information About NanoSynergy Worldwide, Inc.
NanoSynergy Worldwide, Inc (NSWW) is a privately owned Corporation formed in Nevada in 2003
as a Research & Development Company in the field of Nanotechnology. NSWW is the exclusive
Master Licensee for U.S. Patent #6,861,066, a system patent that was issued on March 1, 2005, for a
Method for Delivery of a Biologically Active Agent. The patent describes a unique delivery
process, designed to maximize the product effectiveness of a wide variety of liquids through an oral
spray for humans and animals. In addition, NanoSynergy has exclusive rights to the international
patent pending utilizing this proprietary process for the treatment of Pernicious Anemia employing
its Vitamin B-12 Nano-composition.
The Companys core focus is to implement this patented NanoSyzed process to improve the
delivery of nutriceuticals, pharmaceuticals, cosmeceutical, and agricultural products. This
Nanotechnology is far reaching and the following list describes some of the benefits:
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
faster onset of action

increased absorption
increased bioavailability
increased cellular penetration, activity & function
therapeutic efficacy
no swallowing difficulties
lower dosing needed for effectiveness
bypassing the full digestion process & eliminating stomach upset
eliminate the first pass taxation to liver and kidneys
taken anywhere without water
NSWW works closely with prominent scientists and researchers to develop new innovations in
product formulations and to collaborate with existing nutraceutical and pharmaceutical companies
to assist them in working to better enhance or improve their products. This is accomplished by
reducing the dosage needed, thus reducing or eliminating many of the side effects associated with
supplements or medications. NSWW is dedicated to developing "clinically tested" nano-science
based products that serve the primary needs of the consumer while delivering them a better quality
of life.
For more information about NSWW, please feel free to contact us at: Toll Free 1-877-NSW-NANO,
email info@nanosynergyww.com or Spray For Life Contact.
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Spray For Life FAQ

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Spray For Life FAQ

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Frequently Asked Questions About Spray For Life

Spray For Life and its Patented Technology

Ingredients used in Spray For Life and Why?

What is Vitamin B1?

Order and Payment

Privacy Policy and Terms & Conditions

What information does Spray For Life collect?

Q2: Why do I need to take Spray For Life?

Q3: Which Spray For Life products are available?

Nano B-12 Booster

Q4: What makes Spray For Life so unique and is it patented?

Q5: What is Nanotechnology?

Q6: How is nanotech different from biotech?

Q7: How is Spray For Life related to Nanotechnology?

Q8: What is this patented NanoSyzed process?

Q9: Why is Nano safe?

Q13: What is in Spray For Life?

Q15: Does Spray For Life contain any sugar?

300 times sweeter than sugar

Increases energy levels and mental activity

Q20: What is not in Spray For Life?

Q21: Will Spray For Life interact with my prescription medication?

Q25: Can I take Spray For Life on a plane?

You are currently taking any prescription medicines.

Q27: Is it safe to combine several Spray For Life products together?

Q30: Is Spray For Life affected by extreme temperatures?

Q31: Is it harmful to take outdated/expired Spray For Life?

Lasts up to four (4) hours (not 1 minute like alcohol gels)

For more information, please refer to Shban Power Point Presentation

A short list of benefits of Cyanocobalamin vs Methylcobalamin

Q2: In the Nano COQ10, why Ubiquinone rather than Ubiqunol?

Following the Science

CLINICAL RESEARCH BULLETIN

What's the Best Form of CoQ10, Ubiquinone? - by Dr. Stephen Sinatra

Antioxidant and preservative properties

Q4: What is Potassium Sorbate?

Q5: What is Vegetable Glycerine?

Q6: What is Jujube Extract?

Q7: What is Adenosine?

Do we really need Vitamin Supplements?

-- Dr Robert Fletcher and Dr Kathleen Fairfield (emphasis mine)

25 - 50% get less than the RDA of vitamin A

... and so on.

What are Vitamins?

An organic compound (contains carbon).

There are currently 13 recognized vitamins.

What is Vitamin B1?

- Chemical name (vitaminer) - thiamine

What is Vitamin B2?

- Chemical name (vitaminer) - riboflavin

What is Vitamin B3?

- Chemical names (vitaminer) - niacin, niacinamide

What is Vitamin B5?

- Chemical name (vitaminer) - pantothenic acid

What is Vitamin B6?

- Chemical names (vitaminer) - pyridoxine, pyridoxamine, pyridoxal

What is Vitamin B7?

- Chemical name (vitaminer) - biotin

What is Vitamin B8?

- Chemical names (vitaminer) - Inositol

What is Vitamin B9?

To synthesize DNA, RNA and to repair

To produce healthy red blood cells

- Chemical names (vitaminer) Folate, folic acid, folinic acid