Himalaya Global Holdings Ltd.

(HGH), is the parent of The Himalaya Drug Company

worldwide. The Himalaya Drug Company is in the business of providing scientifically
validated head-to-heel herbal solutions for the entire family. HGH is the owner of the
trademarks and patents, which are licensed to and used by The Himalaya Drug Company in
the manufacture of its products.
U24232KA1997PTC022261 Himalaya Drug Company Private Limited

Every year, 300 million Himalaya products enter the homes of consumers
around the world. With a range of over 300 healthcare and personal care
products including brands like Liv.52, Cystone, and Bonnisan, we touch the
lives of millions of customers worldwide, giving them products that help them
lead healthier, enriched lives.
Himalaya's story began way back in 1930. A curious young man riding through the forests of
Burma saw restless elephants being fed the root of a plant, Rauwolfia serpentina, which
helped pacify them. Fascinated by the plant's effect on elephants, this young man, Mr. M.
Manal, the founder of Himalaya, wanted to scientifically test the herb's properties.
With no money and only a pocketful of dreams, he pawned his mother's jewelry to buy a
hand-operated tableting machine. The years that followed were a time of endurance and a
test of the young man's patience, strength and passion. He spent his days learning about
herbs from neighborhood healers and his nights working on the machine to make a few
hundred tablets. His vision was to 'bring the traditional Indian science of Ayurveda to society
in a contemporary form'.
In a time when herbal products were regarded with scepticism, our founder's belief in the
healing power of herbs was unwavering. He felt that if people were offered safe and
effective herbal medicines, they would come to accept them as part of their healthcare
routine. He believed that herbal medicines could and should be evaluated on the same
quality and efficacy parameters as conventional medicine. This was possible through
empirical research. Once scientific research proved that herbal products worked, even
doctors could be won over. This was a big dream with big challenges. But he persevered on
despite the obstacles.
After four years of researching the herb Rauwolfia serpentina, Serpina, the world's first
natural antihypertensive drug was launched in 1934.
The discovery set the future course for Himalaya. It taught us the value of scientific
research. It also taught us the importance of patience, passion and perseverance. We have

since focused on converting Ayurveda's herbal tradition into a range of proprietary

formulations dedicated to healthy living and longevity.
With a history spanning eight decades in the area of herbal research, Himalaya shares a
close relationship with nature. We are in the business of not only promoting good health but
also safeguarding the health of our planet. Ever since our inception, we have taken great
care to protect biodiversity, collect herbs in a sustainable way and promote good agricultural
practices.

In 1955, Himalaya introduced Liv. 52, a liver formulation that ensures optimum liver
function. The product soon became our flagship brand and a top selling herbal medicine.
Other brands soon followed including Cystone, Bonnisan and Rumalaya forte, products that
went on to become household names.
In 1999, Himalaya entered the personal care segment under the brand name 'Ayurvedic
Concepts'. This was unchartered territory which brought with it new challenges and new
opportunities for learning. People around the world were waking up to the benefits of herbal
and natural products for their personal care needs. Himalaya had close to seven decades of
research experience in herbal medicine and this legacy had helped us understand the world
of herbs. The prospect of entering the personal care space was therefore exciting. We
wanted to give customers herbal personal care products that were mild, gentle, hardworking and steeped in science! Our guiding philosophy was to develop a range of personal
care products rooted in Ayurveda and backed by research, a mainstay of the Himalaya
brand. By remaining true to our research ethic, we built credibility for our range of herbal
personal care products and gained the trust of our customers. A year later, we expanded our
portfolio to include animal health products with the objective of caring for the health and
well-being of animals.
With our expanding range of products and growth in international markets, Himalaya
underwent a rebranding where the entire range was brought under a single umbrellaHimalaya Herbal Healthcare. With the present portfolio of pharmaceuticals, personal care,
baby care, well-being and animal health products, Himalaya has evolved into a 'head-toheel' herbal wellness company.
After close to 80 years, we remain committed to enriching the lives of people who use our
products. Himalaya's therapeutic products have brought relief to people suffering from
ailments like liver disorders, diabetes to kidney stones and joint disabilities. Our personal
care range captures the best in nature and science, giving our customers products that are

gentle, effective and safe for long-term use. Our vision is to offer wellness in every home
and for the whole family through our herbal healthcare and personal care products.
Today, the Himalaya brand is synonymous with safe and efficacious herbal products. Starting
off operations in Dehradun way back in the 1930s, the company later spread its wings to
Mumbai and across the country. In 1975, the company set up an advanced manufacturing
facility in Makali, Bangalore, India. In 1991, the company relocated its R&D facility to
Bangalore.
We operate in over 90 countries, our products are prescribed by 400,000 doctors worldwide,
and millions of customers trust us for their health and personal care needs. Himalaya
Global Holdings Ltd. (HGH) is the parent of all Himalaya subsidiaries.

The Himalaya Logo

The Himalaya brand has much in common with the mountain range from which it draws its
name. For centuries, the Himalayas have been an icon of aspiration and of man's quest to
unlock nature's secrets. They represent purity and lofty ideals.
Our logo is a visual definition of our brand identity. The leaf that forms the crossbar of the
letter H represents the company's focus on herbal healthcare. The teal green reflects our
closeness to nature, while the orange is evocative of warmth, vibrancy and our commitment
to caring.
The Himalaya brand represents wellness, both internal and topical. Our range of head-to-toe
healthcare and personal care products spans the entire wellness spectrum, offering gentle,
safe and efficacious care.

Each and every product that carries our logo is backed by the high quality that is Himalaya's
hallmark. It promises good health, well-being and a prescription for good living. Our logo
symbolizes a promise delivered.
Himalaya's mission is to make herbal wellness a part of every home. We want to be the most
trusted company in scientific herbal healthcare and most admired for our ethics, values and
commitment to sustainability.
Our mission statement reads:

Establish Himalaya as a science-based, problem-solving, head-to-heel brand, harnessed

from nature's wealth and characterized by trust and healthy lives.
Develop markets worldwide with an in-depth and long-term approach, maintaining at
each step the highest ethical standards.
Respect, collaborate with and utilize the talents of each member of the Himalaya family
and the local communities where Himalaya products are developed and/or consumed, to
drive our seed-to-shelf policy and to rigorously adopt ecofriendly practices to support the
environment we inhabit.
Ensure that each Himalaya employee strongly backs the Himalaya promise to exceed the
expectations of the consumer, each time and every time. Nothing less is acceptable.
At the heart of the Himalaya mission is the belief that good health should be accessible to
everyone, and we strive to make this possible through our commitment to science-driven
herbal healthcare.
Life at Himalaya is about being committed to integrity, accountability, fairness, transparency
and innovation.
Integrity: We value the trust our customers, business partners and other stakeholders have
placed in us. By being truthful, consistent and honest in everything we do, we honor this
trust.
Accountability: We are accountable both internally to our team and externally to our
stakeholders. Systems and processes help us ensure accountability at every step.
Fairness: We remain firmly committed to our rules and are guided by our ethics. This helps
us make impartial decisions and treat all parties fairly.

Transparency: Being open in our dealings is integral to our work ethic. Whether it is
interacting with farmers who grow our herbs, vendors who supply us materials or customers
who buy our products, we believe that transparency helps us make partners for life.

Innovation: Bringing ideas out of the lab and into the real world is the kind of innovation
we pursue. It inspires us to discover new medicines and develop new products that go onto
make life healthier and happier for people.

Our People
Himalaya's founder firmly believed that the success of an organization depended on the
quality of its people. The best minds produce the best results. His belief was to hire bright,
passionate individuals who were ready to take on challenges and think 'out of the box'. By
remaining true to this philosophy, we have grown as an organization and continued to
spearhead pioneering research in the herbal space.
Today, we are a family of over 5,000 employees worldwide, including a team of over 200
passionate and energetic research scientists! Years before the 'equal opportunity' mantra
became popular in industry, we have practiced and promoted non-discrimination. In fact,
way back in 1950 our research department was headed by a woman! Today, women makeup
24% of our management staff. We continue to attract people who are talented, driven and
inspired by our vision to bring health and wellness to the lives of the people we touch.
People are Himalaya's most important asset and investing in them is vital to us. From giving
them the creative freedom to push the boundaries of research to fostering a culture of open
communication and diversity, we believe that our nurturing work environment brings out the
best in our team and allows us to develop the best products.
Each and every Himalaya employee is unique and contributes to the success of the
organization. All of us are committed to making a difference.
We believe that the best results come about only when you wake up each morning feeling
excited about your work! In our area of business, where years of research can sometimes
produce no results, staying motivated comes from one's passion for their work. It is the
passion of our people that has given Himalaya a distinctive edge.
Our founder maintained that when you discover people with pure talent and passion, you
should 'create' a job for them. He believed that it is the people with vision and passion who
drive the success of an organization.

Product Categories:

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5.
6.

Pharmaceuticals
Wellness
Personal Care
Animal Health
Baby Care
Nutrition Health

Pharmaceuticals
Inspired by Ayurveda, Himalaya's pharmaceutical range, promoted exclusively through
doctors, addresses multiple health conditions. Our 60 strong product portfolio includes
therapeutics, wellness products, prescription dermaceuticals and oral health products for
men, women and children.
The information in this section is not intended to be a substitute for professional
medical advice. We urge you not to use the same to diagnose or treat your
problem.

Our phytopharmaceutials address lifestyle disorders, chronic illnesses like diabetes and
osteoporosis and life-threatening diseases like Hepatitis B. Our complete range of
preventative care products enhance immunity and assist in the management of health.
Derived from herbs, each product is backed by eight to ten years of research, undergoing
clinical trials, mutagen studies and toxicity tests to ensure safety and efficacy.
Today, Himalaya is ranked thirty-one amongst 500 top pharmaceutical companies in India.
Our brands, Liv.52, Cystone, Bonnisan and Septilin are leaders in their categories. In fact,
Liv.52, a hepato-protective, is the only herbal medicine to be ranked amongst the top ten
bestselling medicines in the country.

Aactaril Soap
Medicated cleansing soap for bacterial and fungal skin infections

Abana

The multifaceted cardioprotective

Althea

Intense moisturizer for dry skin

Bleminor

For blemish-free skin

Bonnisan

Keeps babies healthy and happy

Bonnispaz

Changes colic to frolic in minutes

Bresol

The breathing solution

Chiropex

For comprehensive management of plantar xerosis

Clarina Anti-Acne Cream

Clears acne effectively and safely

Clarina Anti-Acne Face Mask

Controls oil, cleanses pores, clears acne

Clarina Anti-Acne Face Wash Gel

Cleanses skin, controls acne

Clarina Anti-Acne Kit

Comprehensive anti-acne therapy

Clearvital

Clears wrinkles, vitalizes skin

Confido

Restores his confidence

Cystone

The natural choice in urinary calculi and UTI

Diabecon

The beacon of hope for diabetics

Diabecon DS

The beacon of hope for diabetics

Diarex

The dependable antidiarrheal

Diarex Syrup

The dependable antidiarrheal

Evecare

Ensures complete uterine care

Gasex Syrup

Improves digestion

Gasex Tablet

Improves digestion. Relieves gaseous distension

Geriforte

Rejuvenates both BODY & MIND

Hairzone

Prevents hair fall, promotes hair growth

Herbolax

The gentle bowel regulator

Himcocid

The complete antacid, beyond just relief

Himcolin

Strengthens erectile power and improves sexual potency

Himcospaz

The breakthrough antispasmodic

Himplasia

A new dimension in BPH management

HiOra Mouthwash-Regular

Kills germs, tones gums & refreshes mouth

HiOra-GA Gel

Gum astringent gel

HiOra-K Mouthwash

For sensitive teeth and halitosis

HiOra Toothpaste

Toothpaste for inflamed and spongy gums

HiOra-K Toothpaste
For comprehensive management of sensitive teeth and gums

HiOra-SG Gel

The healing stoma gel

HiOwna

Nutrition and good health...Naturally!

HiOwna Momz

Essential nutritional support for mothers!

HiOwna kidz
Balanced nutritional supplement to improve physical, mental and immune development in

children

Koflet

The cough reliever

Koflet Lozenge

Provides the joy of relief

Koflet-H Lozenge

Prompt relief honey rich lozenge

Koflet-SF

The sugar-free cough linctus

Liv.52

Unparalleled in liver care

Liv.52

Unparalleled in liver care

Liv.52 DS

Unparalleled in liver care

Liv.52 HB

Effective management of hepatitis-B

Lukol

Instills confidence in her

Lukol Syrup

Instills confidence in her

Menosan

Helps her glow again

Mentat

Channelizes mental energy

Mentat

Channelizes mental energy

Mentat DS

Channelizes mental energy

Ophthacare

For optimal eye care

Oxitard

The natural antioxidant

Pilex

The medical answer to a surgical problem

Purim

The natural therapy for healthy skin

Renalka

The coolant of the urinary tract

Renalka

The coolant of the urinary tract

Reosto

Bone insurance... lifelong!

Reosto

Bone insurance... lifelong!

Rumalaya

Keeps the joints mobile

Rumalaya (gel)

Mobility unlimited!!!

Rumalaya (liniment)

Rapid action formula for pain...

Rumalaya forte

The dual advantage arthritis control

Septilin

Builds the body's own defense mechanism

Septilin

Builds the body's own defense mechanism

Serpina

Restores normal blood pressure in hypertensives

Speman

Gives hope to childless couples

Styplon

The natural styptic

Talekt

A new advance in derma care

Tentex forte

Effective non-hormonal sex stimulant for men

Tentex Royal

Enhances desire and improves performance

Wellness

Our lives have undergone epic transformations in comparison to our ancestors and so
have the type and number of health issues we face as a society today. While
technological innovations have no doubt made our life easier, these advances have also
given rise to a host of lifestyle disorders. From hair loss to vision problems, cardiac

issues, gastric disorders, carpal tunnel syndrome, anxiety and insomnia, the list is
lengthy and growing day by day. The healthcare industry never goes to sleep because
of the numerous ailments battling for the attention of scientists and medical
professionals. While our choices have become highly specific, so have the ailments that
assail our society.
At Himalaya, our research is propelled by a compelling need to give people a healthier
life. Providing society with a better quality of life through head-to-heel wellness has
always been our niche and passion. Our wellness solutions address a wide spectrum of
medical issues from preventive care to health management. For example, a common
cough and cold, especially before a change of seasons, can easily be prevented by
taking Tulsi every day.
While a bouquet of options exist to treat illness, natural herbal supplements can safely
augment the body's healing and rebuilding process, working in conjunction with
traditional medicine or as a primary option for treatment. With the availability of solutions
that are natural and safe, people have a choice to take control of their healing and lead
a happier, healthier life.

Sleep Wellness

Metabolic Wellness

Cardiac

Weight

Respiratory

General

Womens

Mens

Bowel

Gastric

Immunity

Skin

Mind

Digestive

Personal Care
Himalaya's personal care range was born out of the research strength of our pharmaceutical
products. By bringing the credibility of our pharmaceutical research to our personal care
portfolio, we offer solution-based products that cater to your daily personal care needs. The
range offers the goodness of natural solutions for everyday use, with no side effects. Made
from herbs that are gentle and safe, our range includes skincare, haircare, oral care and
healthcare products.

All

Face Care

Hair Care

Body Care

Oral Care

Lip Care

Eye Care

Health Care

Men's Care

Active Fresh Gel

For a fresh feel

Age Defying Hand Cream

Repairs and protects for youthful hands

Almond & Rose Soap

Fully hydrated

Aloe & Cucumber Refreshing Body Lotion

For a refreshing and cool feel

Anti-Dandruff Hair Cream

All-day confidence in a jar

Anti-Dandruff Hair Oil

Love your healthy, dandruff-free hair

Anti-Dandruff Shampoo

Removes dandruff and soothes scalp

Anti-Hair Fall Cream

Reduces hair fall and promotes hair growth

Anti-Hair Fall Hair Oil

Strong and healthy hair

Animal Health
Himalaya believes that natural health solutions work best for animals too. To this end, we
offer herbal remedies and daily care products for animals, specifically livestock, poultry,
aquaculture and pets. Our range comprises calcium supplement for bone development in
animals, herbal feed supplement for fish, livestock and poultry and natural grooming
products for your beloved pets.

All

Aquaculture

Companion Care

Livestock

Poultry

Baby Care
Himalaya's doctor-endorsed baby care range of products is produced using naturally derived ingredients. They are
developed and tested to be mild to support baby's delicate skin, hair and eyes. Babys hygiene and comfort are kept
as our topmost priority. The products help address conditions like diaper rash and infantile dry skin. Specially
designed baby care products are divided into 'Pre-Bath', 'Bath' and 'Post-Bath' categories.
To know more about our babycare range, you can also visit Himalaya Babycare website

Baby Cream

Keeps babies healthy and happy

Baby Lotion

A natural moisturizer

Baby Massage Oil

Oil massage to health

Baby Powder

To keep cool and stay fresh

Prickly Heat Baby Powder

Ditch the itch

Baby Diapers

The bottom line on diapers

Diaper Rash Cream

For happy baby bottoms

Gentle Baby Shampoo

Hair kept so soft

Gentle Baby Bath

Bath-time, made natural

Gentle Baby Wipes

Simple, smart wipes

Soothing Baby Wipes

Soothes skin and relaxes baby

Gentle Baby Soap

Especially for baby's gentle skin

Extra Moisturizing Baby Soap

Maintains skin's moisture equilibrium

Refreshing Baby Soap

Keeps baby's skin cool and fresh

Nourishing Baby Soap

Gentle nourishment for baby's sensitive skin

Babycare Gift Pack

Babycare Gift Jar

Babycare Gift Box

Babycare Gift Box

Babycare Gift Basket

Babycare Gift Box Mini

Babycare Gift Pack Combi (Soap-Powder)

Nutrition
Himalaya's nutrition health range combines the knowledge of Ayurveda with modern science, to give children and
adults a daily herbal nutritional health supplement that provides the benefits of scientifically validated age-old herbs
along with essential vitamins and minerals.

HiOwna kidz
Balanced nutritional supplement to improve physical, mental and immune development in

children

HiOwna

Nutrition and good health...Naturally!

HiOwna Momz
Essential nutritional support for mothers!

Research

Originating from the two Sanskrit words, ayus (life) and veda (science), Ayurveda is an
ancient healing system originating in the Indian subcontinent that relies on herbs for
maintaining good health. Historical records suggest that the journey of Ayurveda began in
India more than 5,000 years ago, and this traditional system of healing has influenced both
Unani humor therapy conceptualized by Hippocrates and ancient Chinese remedies.

The science and practice of Ayurveda are narrated in ancient texts, of which the Charaka
Samhita is the principal resource. The Charaka Samhita refers to a large collection of Hindu
sacred texts called the Vedas. Written in the Indus Valley area around 1000 BC in Sanskrit,
the Charaka Samhita is a treatise on general medicine. This strongly suggests the probability
that Ayurveda, though of pan Indo-European origins, had begun to evolve into a distinct
entity within the Indian subcontinent by the first millennium BC.
Vedic philosophy believes that human beings are all a part of nature. Just as animals and
plants are interdependent on each other to create balance within their beings, there is a
concurrent and inherent connection between the universe and human beings. Unlike the
animal kingdom, human beings live in a more complex, natural world where they are
perpetually exposed to environmental changes. Changes in weather, society, economy,
lifestyle, diet, work, financial status, emotions and relationships can easily tip the balance
and negatively influence an individual's state of mind, body and soul.
According to Ayurvedic texts, the human body comprises three body states which include
Vata, Pitta and Kapha. Vata consists of the elements air and ether, which give us movement
and activity. Pitta includes the elements fire and water, which are responsible for heat,
appetite and digestion, and Kapha is characterized by the elements earth and water, which
are responsible for water and other bodily fluids. When the three body states are in perfect
harmony, the individual enjoys good health, whereas an imbalance in the states causes
disease. Ayurveda seeks to address this state of imbalance through a process of holistic
healing.
Herbs are at the heart of Ayurvedic medication. Whole flowers, roots, stems and leaves are
manually processed in various ways to discover their optimal potential. Over 15,000 herbs
are mentioned in the scriptures of which only around 850 are commonly used in Ayurvedic
medicine today. One of the most commonly used herbs in Ayurveda is Neem. Described as
sarva roga nivarini or that which keeps all diseases at bay, Neem supports the body's
natural defense system. Apart from Neem, Ginger, Amla and Ashvagandha, among others,
feature highly in the list of important plants in this traditional medicinal system.
Historical records suggest that Ayurvedic medicine has paved the way for various branches
of medicine practiced today. Susruta Samhita, another revered Ayurvedic text, mentions

nine branches in Ayurveda-general medicine, surgery, ear, nose and throat (ENT) and eye
disease, toxicology, psychiatry, pediatrics, gynecology, sexology and virility. Some texts also
reveal that ancient natural healers delved into plastic surgery.
Drawing from this incredible history, Himalaya's mission is to contemporize Ayurveda and
develop safe and effective products to improve quality of life.

Contemporary Ayurveda /
HimalayaScience

Dating back 5,000 years, Ayurveda or the 'science of life' is one of the oldest systems of
natural healthcare in the world. Sometimes referred to as a bioscience, its chief aim is to
cleanse the body of substances that cause disease, thus helping to re-establish harmony
and balance. Primarily botanical, Ayurveda focuses on addressing key foundations that
pertain to health and diseasethe body's constitution (prakriti) and natural forces (doshas).
In the modern world, Ayurveda faces the tough challenge of making a traditional medicinal
system relevant today. The answer lies in the Charaka Samhita, one of the most revered
Ayurvedic texts. It reads:

"Undoubtedly there exists no limitations for (the application of) Ayurveda. Henceforth one
should be vigilantly, incessantly perseverant to apply this science. This is the duty of
(physician, manufacturer, user) all who want to utilize this science. In order to ensure
professional development in this field one should be open to receiving (information) without
indignation to others (sources)...For having observed this the wise should listen and adopt
such things which are wholesome, agreeable, life-giving, promoting and contemporary."
Charaka Samhita 4.8.14. (Circa 1500 BC)
The text suggests that Ayurveda needs to evolve with time. It needs to understand changing
environmental circumstances and address healthcare needs accordingly. The Charaka
Samhita encourages learning and assimilating the best from other forms of healthcare
systems. A synergistic union between modern and traditional medicine will provide the best
healthcare available to patients. This 'hybrid', synergistic system of medicine is practiced by
Himalaya. We call it contemporary Ayurveda.
Our founder, Mr. M. Manal, believed in the potential of herbs and of the various benefits of
traditional medicine. However, he also believed that in order for traditional medicine to be
widely accepted, it needed to be credible. Credibility of drugs can be achieved through
scientific validation.
Himalaya's first drug, Serpina, the world's first natural anti-hypertensive, was born four
years after its initial discovery. Four years were spent on clinical trials, scientific validation
and in discovering the process of making tablets. Mr. Manal believed that in order to make
herbal medicine mainstream, it would need to follow allopathic protocols during
development and be available in a widely accepted format like tablets or syrup. This is the
only way in which Ayurveda could become relevant.
Taking inspiration from this legacy, today Himalaya scientists and herbalists spend years
researching the therapeutic benefits of herbs. We use over 250 herbs in our products, and
each day we study many more. As soon as new benefits of herbs are discovered, we update
our herbal monograph, a guide that gives a basic description of the herb and lists its
chemical constituents, actions, clinical uses and recommended dosage. It's a job requiring
patience and passion. After that, a great deal of time is spent authenticating the herb,
isolating its active marker, testing its therapeutic property and validating safety and efficacy.
The whole process can take anywhere on average between seven to ten years. We believe
that no investment is too much when it comes to developing safe and efficacious products.
We use the most advanced technology available to determine the accuracy, safety and
efficacy of drugs during the development process.

The results of our clinical trials are published in leading medical and peer-review journals.
The backing of empirical evidence and analysis further lends validation to our products.
Today, over 400,000 doctors prescribe our products both as an adjuvant and as the first line
of treatment.
At Himalaya, contemporizing Ayurveda means making the system of traditional healthcare
mainstream. Taking our cue from the Charaka Samhita, we have imbibed the knowledge of
modern medicine in our products, and followed allopathic protocols to develop wellresearched, safe and efficacious drugs.

Research at the Heart

If there is one word that captures the essence of Himalaya, it is research. It lies at the heart
of everything we do. Serpina, the first drug launched by Himalaya, was the result of four
long years of research.
The legacy of researching nature forms the foundation of Himalaya's operations. While
drawing from ancient Ayurvedic texts, our scientists have validated the safety and efficacy
of our herbal formulations using modern science. Each herb is studied in great detail to
establish known and unknown therapeutic benefits. We have studied over 10,000 herbs and
discovered many new properties. In just eight years, we have filed over 90 patents.
At Himalaya, our scientists are driven by the knowledge that plants have immense potential
and can provide solutions to improve life. For instance, herbal medicines are typically not
explored for the treatment of life threatening diseases. The reasons attributed are two-fold
the dearth of scientifically-validated herbal medicines and the lack of awareness about
alternative drugs.
Yet, our scientists are busy researching herbal drugs for conditions like cancer, depression
and women's health, amongst others. Recently, we have launched a drug for Hepatitis B, a
condition that affects 40 million people in India, alone. The drug, which has taken 14 years
to develop, works at an efficacy rate comparable to allopathic medicines, at a fraction of the
price and with no side effects!
At Himalaya, research is not just about breakthrough formulations but also about filling the
gaps in conventional medicine. We believe that herbal remedies can become the first
treatment of choice for some conditions, and at other times, contribute to a holistic regimen
that improves the quality of life. For instance, our cancer drug presently undergoing trials
helps build immunity in patients on chemotherapy.

Through research, Himalaya has introduced several innovative products. Cystone, Himplasia
and Septilin are some of our breakthrough drugs that are prescribed by doctors across the
world. Cystone, used in the treatment of urinary stones, is the only herbal drug available for
this condition. It is backed by over 90 clinical trials. Himplasia is the first herbal formulation
that controls benign prostate hyperplasia. The efficacy of these drugs is comparable to
allopathic medicines, without any side effects! While herbs may not provide the answer to all
unmet medical needs, they can make a significant contribution to overall healthcare.
We have applied the research strength of our pharmaceutical products to consumer care as
well. A patent has been filed for our Under Eye Cream. Research is currently underway to
offer a wider range of products in the anti-aging and dermaceuticals space.
At Himalaya, we will continue to focus on research and build credibility for herbal medicines
and personal care products. Our customers understand that all our products are a result of
years of research. Today, over four million doctors and customers in over 80 countries rely
on us for their healthcare and personal care needs.

R&D Centre
Himalaya has invested in a state-of-the-art Research & Development (R&D) center in
Bangalore, India, which encompasses over 80,000 square feet of space. The center is ISO9001: 2008 certified.
We have a team of more than 200 physicians and scientists working in our R&D facility. Our
scientists come from disciplines as diverse as analytical chemistry, formulation and
development, phytochemistry, new drug discovery, novel drug delivery systems,
pharmacognosy, preclinical toxicology and pharmacology, invitro mutagenecity, clinical
pharmacology and agriculture. This vast and diverse background of the R&D team gives us
unique insights into the world of herbs, helping us understand, discover and develop
breakthrough products.
The use of advanced technology ensures accuracy, efficacy and safety of each and every
product. For example, we use the liquid chromatography-mass spectrometry (LCMS) method
during herb testing. LCMS separates each molecule from a given extract and helps identify
its chemical nature. This technology is used in the specific detection and potential
identification of chemicals in the presence of other chemicals in a complex mixture. The
advantage of using LCMS lies in the fact that it is an extremely accurate method of analyzing
the total marker profile of a given extract. The technology helps our scientists to standardize
all compounds in a given herbal extract before the product is developed.

In March 2001, we were granted a Good Manufacturing Practices (GMP) certificate, issued by
the Licensing Authority, Directorate of Indian Systems of Medicine, Bangalore, India.
Himalaya is the first Ayurvedic facility to get GMP certification in India. We have also been
granted the Good Laboratory Practice (GLP) certification. A GLP certification is granted to
manufacturing companies that adhere to the toxicity guidelines in nonclinical safety studies.
The certification is granted by the National Good Laboratory Practice (GLP) Compliance
Monitoring Authority, Department of Science and Technology, Government of India. Only 26
institutions in India have been granted this certificate, and Himalaya is the first herbal
company to have joined ranks with these institutions.
Himalaya's R&D center is affiliated with one of India's leading universities, The Rajiv Gandhi
Institute of Health Sciences in Bangalore, and is recognized as a Center for Research by the
Government of India's Department of Science and Technology. We work closely with the
University of Agricultural Sciences in Bangalore to develop new therapeutic drugs, build a
corpus of knowledge on herbs and protect endangered herbs and plants.
We have partnered with the Ras Al Khaima Medical Health & Science University, a leading
university in the United Arab Emirates, to promote joint research collaboration in herbal
medicine including clinical trials, joint conferences, faculty and student exchange programs,
and joint research and publications.
The R&D Center is a vital institution of higher learning. Several PhD students from
universities across India conduct their research at our center under the supervision of
Himalaya scientists. This is a great opportunity for us to engage with bright minds of the
future and be inspired by their ideas and enthusiasm.

Formulating a Herbal Drug

All herbal formulations at Himalaya find their roots in classical Ayurvedic texts. A team of
botanists and Ayurveda experts at our R&D center review these scholarly texts and shortlist
suitable herbs for further research. The availability and sustainability of these herbs are first
ensured before research is initiated.
Himalaya's phytochemistry team studies the geographical and seasonal variations of marker
profile of these herbs. Active markers within these herbs, which are responsible for its
therapeutic property, may vary depending on whether they are cultivated or sourced from
the wild. Phytochemical profiling is established from different seasons and geographical

locations to ensure batch-to-batch consistency, good quality and standardization. The

quality of herbs is further maintained either by cultivating herbs under supervision of
agricultural scientists or by practicing sustainable collection and harvesting practices under
the supervision of trained botanists (in case of herbs sourced from the wild). Herbs have to
further pass through stringent quality checks as per internal specifications laid out by our
scientists.
With a focus on taking herbal research to new levels, Himalaya's scientists have adopted
bioassay guided fractionation and purification technology to identify the active fractions.
This ensures that the herbal preparation is standardized and formulation has required levels
of bioactive compounds to elicit the pharmacological response. This technology will continue
to help in identifying phytoactive principles responsible for efficacy, synergy and
bioavailability. Himalayas scientists are leveraging this technology for innovative treatments
of ailments including cancer, diabetes and depression as well as for specialized products in
skin, oral and hair care categories.
Super Critical Fluid (SCF) extraction is one of the fast growing technologies for extracting
herbal materials without using chemical solvents. Himalayas scientists are leveraging this
technology during research and development for the extraction of beneficial bioactive
compounds. This ensures no solvent residues in herbal preparation while delivering to the
safety and efficacy of the products.
Extracts from single herb or a combination of herbs are initially tested on disease models of
cell lines to evaluate the efficacy of the drug. Once efficacy is confirmed, these extracts
undergo rigorous toxicity tests and mutagen studies to ensure that it is safe to test on
humans. The extracts are formulated into the desired dosage forms (capsules, tablets, etc)
and then enter human clinical trials. All clinical trials follow Indian and international norms
on human subject testing.
Once safety of the drug has been established, it goes through three phases. The numbers of
patients increase in each phase before the drug is launched into the market. In Phase 1, the
drug is administered to a small number of healthy human subjects to assess safety of the
formulation. Both Phase II and Phase III studies are conducted to assess the true efficacy in
patients suffering from the disease. These studies are undertaken in leading hospitals and
institutes across the world.
We have conducted clinical trials for our products in leading hospitals in India and worldwide
including the All India Institute of Medical Sciences (Delhi), Apollo Hospitals (Chennai), St.
John's Hospital (Bangalore), IMS BHU (Varanasi), Mayo Clinic (Rochester, New York), the

Central Institute of Tuberculosis of The Medical Academy of R.F., (Moscow, Russia), The
Novosibirsk Research TB Institute (Russia), and Charles University (Prague). Himalaya has
over 1,200 published clinical trials in leading international journals including Journal of the
American Medical Association (JAMA), Alternative Medicine, Indian Journal of Pharmaceutical
Sciences, The British Journal of Radiology and Journal of Ethnopharmacology.
Phase IV studies are also conducted by Himalaya, which involve the safety surveillance
(pharmacovigilance) and ongoing technical support of a drug after it receives permission to
be sold.

New Research Areas

At Himalaya, our scientists are conducting exciting research in the field of oncology, AIDS,
lifestyle related disorders and women's health.
Himalaya's anti-cancer drug project has been underway for the past eight years. Cancer is a
result of abnormal cell growth in the body, and once detected, various chemical drugs are
administered to stop or eliminate the cell growth. However, these drugs come with a host of
side effects, which include nausea, lethargy and hair loss. Herbs have been under the
scanner in various research institutes internationally to find an alternative solution for the
disease. Globally, Turmeric's principal constituent, curcumin, has been extensively studied
by Western researchers and scientists for its antioxidant activity. Researchers continue to
study curcumin in relation to normal cell growth ('Common Indian Spice Stirs Hope', Wall
Street Journal, 2005).
At Himalaya, researchers have been testing different herbal extracts to find the one that can
stop the spread of cancer with no side effects. Our team is developing a drug that will either
work as an adjuvant to already available cancer therapies, or be prescribed as a first line of
treatment. While the effectiveness of the drug may be at par with conventional medicine,
the focus is on developing a herbal solution formulation that is safe and free from side
effects. Our formulations are currently being tested on cell lines.
We have also been working on developing an immunomodulator for the past nine years.
Herbs are made of many compounds. Rigorous research has been performed to discover the
most efficacious and safe chemical active in the herb which will stimulate the immune
system. Our formulation has now reached the clinical trial stage.
Diabecon is Himalaya's current offering for diabetes. Studies have shown that the drug is
known to lower blood sugar levels in insulin-dependent diabetes mellitus (IDDM) and
non-insulin-dependent diabetes mellitus (NIDDM) patients. When prescribed as an adjuvant,

it reduces the dosage of oral hypoglycemic agents (OHAs) by 30-50% and that of insulin by
20-30%. Diabecon is prescribed by many doctors as a first line of treatment for diabetes.
Our R&D team is currently researching formulations to address secondary diabetes-related
complications in areas of neuropathy, nephropathy and retinal complications.
Psoriasis is another medical condition for which formulations are currently being clinically
tested. It is a chronic, noncontagious autoimmune disease that affects the skin and joints.
The team at Himalaya has been working for the past three years to find a remedy for the
disease. Over 250 plants have been screened to identify herbs or a composition of herbs
that possess all the therapeutic properties required to treat the disease. A unique herbal
composition has shown positive results on cell lines. During the next phase of testing, this
new herbal composition will pass through stringent efficacy trials in order to arrive at
successful topical and oral treatment options for psoriasis.
In the past year, our researchers have discovered potential herbs for the prevention and
treatment of various conditions. The team is working on drugs for malaria, women's health,
the herpes simplex virus (HSV) and HIV. The research for these conditions is at various
preclinical stages. Some compositions are being tested on cell lines and others are still being
researched to extract maximum therapeutic benefits.
At Himalaya, we place the utmost importance on research. Often, our scientists recall
moments during research when testing a particular herb for one medical condition paved
the way for another! Himplasia, our product for Benign Prostrate Hyperplasia (BPH), came
about due to one such accidental discovery. The success of Himalaya is our ability to deliver
effective, novel drugs, and research is the only way to get there!

Integrated Healthcare
Until recently, traditional herbal medicines were looked upon as the last resort in patients
seeking treatment. Ayurveda was associated with ageing vaidyas or Ayurvedic physicians
selling remedies for everything - from hair loss to cancer, in unlabeled bottles and jars!
Recently, however, a 'back to nature' movement is gaining momentum, where
well-researched herbal remedies are gaining credibility worldwide.
Arguably, conventional medicine is effective in treating various medical conditions. However,
more often than not, chemical drugs have side effects, which can even be fatal. Despite this,
patients tend to choose allopathic medication over herbal drugs because of the lack of
researched, scientifically validated, safe and effective herbal medication.
Today, there is growing acceptance of integrative medicine, where traditional systems of
medicine like Ayurveda are dovetailing into conventional medicine to provide holistic

treatment regimens. Integrated medicine does not accept traditional medicine uncritically.
Instead, it demands as much scientific validation from alternative medicines as it does from
conventional systems of medicine. By bringing together the best of both systems,
integrative medicine gives patients access to healthcare based on good science, holistic
therapies, and curative and preventative treatments. Herbal medicines are now being used
to treat disorders like diabetes, hypertension and obesity. For diseases requiring long-term
treatment, healthcare professionals, including allopathic doctors, are turning to clinically
validated herbal medicines.
Herbs like Neem and Ginger are being researched for their therapeutic properties in various
research centers in India and all across the world. Scholars from the Department of
Microbiology at the Rajah Muthiah Medical College, Annamalai University, India, studied the
skin supportive effects of the seeds and leaves of the Neem plant and found the results to
be 'statistically significant' (Indian Journal of Medical Microbiology 2003 Apr-Jun;21(2):98101).Similarly, scientists at the Department of Complementary and Alternative Medicine,
John A. Burns School of Medicine, University of Hawaii, noted Ginger's use in supporting the
body's natural response to nausea, calling it a herb that integrates East with West and old
with new, enjoying a reputation as a 'universal remedy' (Hawaii Medical Journal. 2007
Dec;66(12):326-7).
It has been our mission to deliver well-researched, clinically tried and tested herbal drugs
from our inception. We have supported the thinking that a traditional system of medicine
can be useful only when it is backed by modern scientific research. Liv.52, a hepatoprotective and Himalaya's flagship brand, is prescribed by allopathic doctors. In many
Russian hospitals, Liv.52 is prescribed as an adjuvant in the treatment of tuberculosis to
address the side effects of medication on the liver. We believe that Liv.52 attained success
due to the research and scientific validation backing it. Until today, 195 clinical papers and
81 experimental papers on Liv.52 have been published in medical and peer-reviewed
journals worldwide. It is a registered drug in over 30 countries and the only hepatoprotective medicine with a meta-analysis study in infective hepatitis. Studies show that
Liv.52 reduces the occurrence of hepatotoxic reactions and helps normalize the level of lipid
peroxidation when used as an adjuvant during the treatment of tuberculosis.
In a similar success story, Cystone, used in the treatment of urinary stones, is the only drug
available for this condition. It has undergone 90 clinical trials, and results are seen in more
than 70% of patients.
Going forward, the shift toward integrative medicine will continue, and natural systems of
medication, like Ayurveda, will become an important part of therapy. This shift will be fuelled
by the availability of scientifically validated and clinically-tested herbal medication. This will
increase patient confidence in the efficacy of herbal drugs on their own or as adjuvants to

allopathic medication.
At Himalaya, we are committed to delivering well-researched, safe, effective herbal medicine
that is accessible to everyone. We believe that a synergistic approach to medicine benefits
patients by providing them with more effective treatment options, helping them manage
their health better and enhancing their overall quality of life.