Curriculum Vitae

Alain Kupferman

Born
Residence
Marital status
Nationalities

13 / 12 / 1942 in Aix-en-Provence, France

Bangkok, Thailand
Married, 3 children
Belgian and French

Education

Secondary school in Antwerp, Belgium

School of Pharmacy in Brussels, Belgium
(Universit Libre de Bruxelles)
Industry Pharmacy study in Brussels, Belgium
(Universit Libre de Bruxelles), title of Industry
Pharmacist (QP) granted by Belgian Ministry of Health

Army service

Major, Medical Service, Belgian Army

Languages

French, English, German, Flemish and working

Knowledge of Indonesian-Malay, Spanish

Address

106 Soi 7, Wong Sawang Road

Bang Sue, Bangkok 10800
Thailand

Telephone (landline)
Telephone (cellular)
E-mail
Skype address

+ 66 - (0)2 - 913 0046

+ 66 - (0)91 - 003 9577
a.kupferman@mac.com
alain.kupferman

Alain Kupferman

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Curriculum Vitae
Alain Kupferman

Experience

Active in the pharmaceutical industry since 1967

Career
1967 - 1969
R.I.T.
Genval, Belgium
1969 - 1973
Ciba Geigy
Stein, Switzerland

Assistant to the Production Management

Manager Ointments Department (30 persons)

Manager Injectables Department (110 persons)

1973 - 1980
Bayer AG
Leverkusen, Germany

Technical Co-ordinator Pharmaceutical Production

Europe
Technology Co-ordinator (Injectables, cosmetics, dietetics)
Project management, investments
Start-up of new factory in Korea
GMP Documentation for affiliates

1980 - 1986
PT Bayer Indonesia
Jakarta, Surabaya,
Indonesia

Technical Director and Plant Manager (360 persons)

Start-up of chemical, cosmetic, dental and animal health
production activities
Plant Manager Pharmaceuticals
Development of Quality Systems

1986 - 1989
Roche
Basle, Switzerland

Project Manager Vitamins Division

Start-up of new product line (dietetic oils)

1990 - 1992
Fisons plc
Loughborough, UK

Technical Co-ordinator Overseas

Project Management, Investments, Quality Audits

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Curriculum Vitae
Alain Kupferman

1992 Industry consulting for the pharmaceutical industry

Planning and conceptual design of factories, with
activities in Bangladesh, Belgium, Bosnia, Brazil, China,
Costa Rica, Croatia, Czech Republic, France, Germany,
India, Indonesia, Korea, Poland, Serbia, Switzerland,
Thailand, Viet Nam
Special fields:

Feasibility and conceptual studies, Master planning

GMP aspects:
audits, training and site visits (with WHO)
audits with Certipharm, France
Technological aspects:
choice of technologies, rationalisation, audits
Personnel training:
technology, GMP, quality matters, etc.

2006 - 2012

Lecturer at the Universit de Strasbourg, France, Faculty

of Pharmacy

2014 -

Lecturer at the King Mongkhut University of Technology,

Thonburi, Thailand
Lecturer at the Chulalongkorn University, Faculty of
Pharmacy, Bangkok, Thailand

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Alain Kupferman

Main consulting references:

ANB, Thailand
Technical evaluation of site for capacity expansion, planning of
injectable hormone facility
Asofarma, Argentina
Conceptual design of influenza vaccine plant and pre-filled syringes
production unit
Biofarma, Indonesia
Concept new DTP vaccine production units
BioNet, Thailand
Concept new vaccine bulk production and formulation units
Boram, Korea
New factory design (manufacturing, packaging, GMP and
technology concept)
Bosch Packaging, Germany
Personnel training (development of training modules, training
sessions for sales and production personnel)
Bosnalijek, Bosnia-Herzegovina
Concept for R&D Centre, with pilot plant, microbiological laboratory
and analytical development, training activities
Byk Gulden, Brazil
Concept new factory (liquids, solids, ointments, packaging,
weighing station and logistics)
Byk Gulden, Germany (now Altana)
Design of production unit for syringes for radiographic contrast
media
Choongwae, Korea
New factory design (infusion bags and bottles, manufacturing,
packaging, GMP concept)
Dae Hwa, Korea
New factory design (hormone products)
Dong Wha, Korea
New factory design (manufacturing, packaging, GMP and
technology concept)
Ely Lilly, France
Concept extension filling capacity insulin products
Farmatrix, Haiti
Concept new factory (solids, liquids, LVPs)
Galenika, Serbia
Quality assistance for development of concept and design of a new
solids facility
Gedeon Richter, Hungary
Concept pilot plant for solid forms (hormones and non-hormones)

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Alain Kupferman
Gufic, India
Concept new factory (solids, ointments, chemical synthesis, GMP
concept)
Gutis, Costa Rica
New factory design (concept, basic design, purchasing equipment,
GMP concept)
Haffkine Bio-Pharmaceuticals, India
Concept for revamping oral polio vaccine production, master batch
records, production and qualification documentation, assistance for
WHO site visits, concept for DTP production
Hanmi, Korea
Concept for API plant (biotechnology products)
Concept for solids production plant
Audit Cephalosporin plant
Hanwha, Korea
Concept for new factory, with hormones department
Haupt Pharma, Germany
Concept for revamping and GMP-upgrading
ICA Pharmaceuticals, Viet Nam
Concept for injectables production, study for revamping solids
production, design of new ophthalmics facility
Ildong, Korea
Concept new production units for cephalosporin and cytotoxics
Ilyang, Korea
Concept new production units for solid and liquid products, as well
as APIs
Integra, Uzbekistan
Concept new factory for injectables
IVAC, Viet Nam
Technical assistance for WHO grant for new influenza plant
Conceptual design of influenza vaccine plant
Kwangdong, Korea
Design review (cytotoxics and conventional products)
Lonza, Czech Republic
Concept fully automated weighing station
Lotus Pharmaceuticals, China
Development of concept and basic design for the production of
narcotics
MDS Nordion, Belgium:
Concept new factory, design of water systems
Merap, Viet Nam
Concept new factory for solids, liquids, injectables, ophthalmics,
including beta-lactames
Panacea-Biotec, India
Conceptual help in design of factories for vaccines production
(various types), GMP consulting and personnel training, preparation
of inspections
Alain Kupferman

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Curriculum Vitae
Alain Kupferman
Pliva, Croatia
Concept new production unit for ointments
Pliva, Croatia and Poland
Concept new factory for effervescent forms
Razi Institute, Iran
Preparation of dossier for WHO grant (influenza production unit)
SAMA, Korea
Concept new factory (solids, packaging, weighing station and
logistics, candies)
Sanbe, Indonesia
Concept new production for large and small volume parenterals
Sartorius, Germany
New filter production facility: validation master plan, hygiene
concept
Schering AG, Brazil
Concept new factory (solids, injectables, packaging, weighing
station and logistics, hormones and non-hormones)
Schering AG, Germany:
Audit review of design for new injectables facility
Soho, Indonesia
Concept new factory for herbal drugs
Concept new production facility for liquids and solids, injectables
and beta-lactames
Square Pharmaceuticals, Bangladesh
Concept new production unit oral liquids
Torlak Institute, Serbia
Concept and follow-up new production units for OPV (oral polio
vaccine) and influenza vaccine, including WHO technical dossier
UCB, Belgium
Design of weighing station, assistance for purchasing and set-up
UNIDO
GMP training of African industry pharmacists and inspectors
WIBP, China
Concept new Rotavirus vaccine production units
World Heath Organisation (WHO)
see chapter below
Yooyoung, Korea
Concept new factory for production of solids, injectables, as well as
logistics, validation master plan (betalactame and non-betalactame
products)
Yuhan, Korea
Concept new factory for production of solids, liquids, injectables,
ointments, betalactames, animal health products, as well as
logistics, validation master plan
Yuyu, Korea:
Concept new factory for production of solids, liquids, ointments, as
well as logistics, validation master plan
Alain Kupferman

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Alain Kupferman
Zdravlje, Serbia
Concept for revamping existing factory and development new
factory (solids, liquids, injectables, ointments)

WHO Activities
GMP audits ( with WHO as GMP expert or as preparation for
WHO site visits )
WHO site visits (vaccine production)
NCPID, Bulgaria
Tianyuan, P R China
BCG Laboratories, Japan
Biofarma, Indonesia
Novartis Behring, Germany, India and Italy
GPO and Sanofi-Mrieux-GPO, Thailand
Bharat, India
Serum Institute, India
Institute for Experimental Medicine, Russia
BCHT, Changchung, P R China
WHO site visits (API and finished pharmaceuticals production)
NCP, Second Pharma, P R China
Jiangsu Bioengineering, P R China
Beximco, Bangladesh
Panacea-Biotec, India
Haffkine Bio-Pharmaceuticals, India
Sanbe, Indonesia
Training of pharmaceutical inspectors
Cairo, Egypt, 2001 and 2009
Sarajevo, Bosnia Herzegovina, 2001
Nanjing, P R China, 2009
Kampala, Uganda, 2010
Oman, Sultanate of Oman, 2012
Preparation of supplementary GMP training modules, 2002
Missions on behalf of SEARO and UNICEF in DPR Korea,
2006, 2007, 2008 and 2010 (GMP training, audits at
Jeongseong and Pyongsu pharmaceutical factories, technical
assistance for LVP production)
Mission on behalf of WPRO in Mongolia, 2007 (assessment of
local pharmaceutical industry)
Training mission in South Africa 2008
GMP Training of GPO, Thailand, 2009
GMP training mission in Indonesia (hazardous drugs), 2009
GMP training mission in Indonesia (pre-qualification), 2010 and
2013
Alain Kupferman

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Curriculum Vitae
Alain Kupferman

GMP training missions for the industry and the SFDA in P R

China (pre-qualification), 2010, 2011, 2012, 2013 and 2014
GMP training mission in India (pre-qualification), 2010
GMP training mission in Kenya (pre-qualification), 2011
GMP training mission in Kenya for regulators and industry, 2011
GMP training mission in Zimbabwe (pre-qualification), 2013
Preparation of Assessment tools (APIs, OSDs) for the SFDA of
P R China
GMP training mission in Pakistan (pre-qualification), 2014

Euro Health Activities

Mission in Kazakhstan, to assist the control laboratory of the
National Center for Drug Evaluation in Almaty

USAID Activities
Missions in Armenia, 2008 (assessment of local pharmaceutical
industry) and 2009 (GMP training of industry representatives and
pharmacy inspectors)

PATH Activities
Mission in P R China, 2010 (GMP consulting at the Chengdu
Institute for Biological Products)
Mission in India, 2011 (GMP mock audit at Serum Institute) and
2013 (GMP mock audit at Bharat Biotec)
Mission in P R China, 2012 (Factory planning at the Wuhan Institute
for Biological Products)

Teaching activities at Faculty for Pharmacy,

Universit de Strasbourg, France, KMUTT, Thailand
and Chulalongkorn University, Thailand as lecturer
(Masters Degree)

Concept Foundation Activities (Reproductive Health)

Missions in Indonesia (PT Tunggal, PT Harsen) in 2012
Missions in Bangladesh and Thailand in 2012

GMP-Auditing activities with Certipharm

Audit of API suppliers and finished goods manufacturers
Missions in Austria, China, Czech Republic, DPRK, France,
Germany, India, Macau, Mongolia, Oman, Spain, Switzerland, UK
Alain Kupferman

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Curriculum Vitae
Alain Kupferman

Technical assistance and certification in DPRK and Mongolia

GMP-Auditing activities with Partnership for Supply

Chain Management
Audit of finished products manufacturers and wholesaler in China

Planning activities related to vaccines and

biotechnology
Asofarma, Argentina
Conceptual design of influenza vaccine plant and pre-filled syringes
production unit
Biofarma, Indonesia
Concept new DTP vaccine production units
BioNet, Thailand
Concept new vaccine bulk production and formulation units
Haffkine Bio-Pharmaceuticals, India
Concept for revamping vaccine production, master batch records,
production and qualification documentation, assistance for WHO
site visits
Concept for DTP production
IVAC, Viet Nam
Technical assistance for WHO grant for new influenza plant
Panacea-Biotec, India
Conceptual help in design of factories for vaccines production
(various types), GMP consulting and personnel training, preparation
of inspections
Conceptual design of influenza vaccine plant
Razi Institute, Iran
Preparation of dossier for WHO grant (influenza production unit)
Torlak Institute, Serbia
Concept new production units for OPV (oral polio vaccine) and
Influenza vaccine, including WHO dossier
WIBP, China
Concept new vaccine bulk production and formulation units
Other training activities
GMP training for Iranian Veterinary Association in Teheran, 2010
GMP Training for Iranian Pharmaceutical Industry, 2013 and 2014
Various training sessions at Chulalongkorn University, Bangkok,
Thailand

Alain Kupferman

CV AK_1502_E.doc