Professional Documents
Culture Documents
Author
John E McClay, MD Associate Professor of Pediatric Otolaryngology, Department of Otolaryngology-Head and
Neck Surgery, Children's Hospital of Dallas, University of Texas Southwestern Medical Center
Background
Adenoidectomy is the surgical procedure in which the adenoids are removed. Adenoids are lymphoid tissue
located in the back of the nose. They are often not understood by the lay public or by physicians who are not
otolaryngologists because they are not observed during routine physical examinations because of their
location. Although the tissue composition of adenoids is the same as that of the tonsils, the diseases
associated with infected adenoids differ from the diseases associated with infected tonsils, based on their
location. This causes additional confusion because the adenoids are often simultaneously grouped with the
tonsils when reporting outcomes in scientific journals.
An adenoidectomy is often associated with other surgical procedures (eg,tonsillectomy, placement of
tympanostomy tubes). In fact, throughout most of the 20th century, tonsillectomies were usually performed in
conjunction with adenoidectomies. Despite more than 50 years of research, some controversy is still
associated with the indications for adenoidectomy. Most often, an adenoidectomy is performed in pediatric
patients. The focus of this article is pediatric adenoidectomy.
In the 1930s and 1940s, the widespread use of tonsillectomy and adenoidectomy (T&A) became controversial
because (1) antimicrobial agents were developed to help treat tonsillitis and adenoiditis, (2) the fact that a
natural decline in the incidence of upper respiratory infections in older school-aged children became evident,
(3) some studies were published showing that tonsillectomy and adenoidectomy (T&A) was ineffective, and (4)
an increased risk of developing poliomyelitis following tonsillectomy and adenoidectomy (prior to the vaccine)
was recognized. Once the opinion pendulum began to swing towards avoidance of surgery, good prospective
clinical trials, which have been performed over the last two decades, were required to prove to the medical and
lay community that good indications for tonsillectomy and adenoidectomy (T&A), tonsillectomy alone, and
adenoidectomy alone, exist
Epidemiology
Frequency
Obtaining current information is difficult because adenoidectomy is usually performed in outpatient settings, for
which data are not well regulated or recorded. Good information was recorded during the 1970s and 1980s
when the procedure was mainly performed in inpatient settings. In the United States in 1971, more than 1
million tonsillectomy and adenoidectomy procedures, tonsillectomies alone, or adenoidectomies alone were
performed, with 50,000 of these procedures consisting of adenoidectomy alone.
In comparison, in 1987, 250,000 combined or single procedures were performed, with 15,000 consisting of
adenoidectomy alone. However, starting in this time period, outpatient tonsillectomy and adenoidectomy
(T&As) and adenoidectomies were being performed more often, which may account for a possible
underestimation of the total number of surgeries performed. In current practice, almost all adenoidectomies
alone are performed in outpatient settings unless other issues or medical problems require hospital admission
or an overnight stay. Additionally, tonsillectomy and adenoidectomy (T&A) is also usually performed in an
outpatient setting, unless the child is young or other issues or medical problems require hospital admission or
an overnight stay.
Probably the best source to obtain the true incidence and frequency of the procedures is data from all the
managed health care companies throughout the United States. Tonsillectomy and adenoidectomy (T&A) is
considered the most common major surgical procedure in the United States.
Etiology
Adenoids, shown in the images below, are on the posterior nasopharyngeal wall posterior to the nasal cavity,
shown below. They develop from a subepithelial infiltration of lymphocytes in the 16th week of gestation. They
are a component of the Waldeyer ring of lymphoid tissue, which is a ring of lymphoid tissue in the oropharynx
and nasopharynx that consists mainly of the adenoids, the palatine tonsils, and the lingual tonsils.
Adenoids immediately following removal. This specimen is approximately 2 cm wide and 1 cm high.
Picture of the tonsils superiorly and adenoids inferiorly immediately following removal. Note the centimeter scale on the pen.
A rigid rhinoscopy photograph of the posterior nasal cavity, nasopharynx, and adenoids. The photograph shows the posterior
portion of the left inferior turbinate in the right corner, the posterior portion of the left middle turbinate in the superior mid
area, and the septum on the left-hand side. The adenoids are in the center, completely blocking the choanae. The floor of
the nose is shown inferior to the adenoid bed.
Adenoids are present at birth and then begin to enlarge. They, along with the tonsils, continue to grow until
individuals are aged 5-7 years. The adenoids usually become symptomatic, with snoring, nasal airway
obstruction, and obstructed breathing during sleep, when children are aged approximately 18-24 months. By
the time children reach school age, the adenoids normally begin to shrink, and, by the time children reach
preteen or teenage years, the adenoids are usually small enough for the child to become asymptomatic.
At birth, the nasopharynx and, thus, the adenoids, are accessible to many organisms. The establishment of the
upper respiratory tract is initiated at birth. By the time children are aged 6 months, lactobacilli, anaerobic
streptococci, actinomycosis, Fusobacterium species, and Nocardia species are present. Normal flora found in
the adenoid consists of alpha-hemolytic streptococci and enterococci,Corynebacterium species, coagulasenegative
staphylococci, Neisseria species,Haemophilus species, Micrococcus species,
and Stomatococcus species. The adenoids can become infected and harbor pathogenic bacteria, which may
lead to the development of disease of the ears, nose, and sinuses.
Pathophysiology
Based on the current literature, adenoids can contribute to recurrent sinusitis and chronic persistent or
recurrent ear disease because they can harbor a chronic infection. The type and amount of pathogenic bacteria
seem to vary based on the disease present and the age of the child. [1]
Overall, the most commonly cultured bacteria have been Haemophilus influenzae,group A betahemolytic Streptococcus,
Staphylococcus
aureus,
Moraxella
catarrhalis, and Streptococcus
pneumoniae, usually in that order. The author has found resistant bacteria of the 3 most common pathogens of
otitis media and rhinosinusitis (ie, H influenzae, M catarrhalis, S pneumoniae) in children with those diseases.
Adenoidectomy, regardless of size of the adenoids, has improved the signs and symptoms of rhinosinusitis and
has reduced the recurrence of persistent middle ear effusions or infections in studies evaluating children older
than 3 years.
causing nasal airway obstruction. Even more confusing is the fact that Maw and Speller found the same
amount of pathogenic bacteria in the adenoids and tonsils of patients with otitis media with effusion as was
found in patients without any head and neck disease.[4]
Regardless of the mechanism, adenoidectomy, independent of the size of the adenoid, has been shown to be
effective for resolving chronic persistent otitis media with effusion and possibly recurrent otitis media in children
older than 4 years. Adenoidectomy in children younger than 3 years has been shown to be safe, but its
effectiveness for treating recurrent otitis media or rhinosinusitis is not proven.
Whether the bacteria that are harbored in the adenoids cause irritation of the eustachian tube lining, resulting in
dysfunction, or the harbored bacteria cause a chronic low-grade infection in the middle ear space, resulting in
persistent fluid or recurrent infections, remains unclear.
Chronic sinusitis
For patients with chronic sinusitis, the adenoid appears to act as a reservoir of infection. This is based on the
improvement observed following adenoidectomy independent of the weight of the adenoids in children with
symptoms of chronic sinusitis as shown by Lee and Rosenfeld in 1997. [5] Additionally, Brodsky et al showed that
the same pathogenic bacteria in the adenoids were cultured from the middle meatus near the anterior sinus
drainage site.[6] McClay also showed that resistant bacteria were found in the adenoid bed. [7]
Presentation
Children who benefit from adenoidectomy can have several different clinical presentations. Children who have
recurrent or persistent otitis media may benefit from adenoidectomy independent of the size of the adenoid
pad. Hence, these children may or may not present with nasal airway obstructive symptoms (eg, nasal
congestion, snoring, sleeping with open mouths) because their adenoids may not be enlarged. However, often
these children do have some form of nasal congestion or snoring. The respected prospective studies to date
only include children aged 3-4 years and older. The effectiveness of adenoidectomy for resolving otitis media in
children younger than 3-4 years who have small- or moderate-sized adenoids has not been addressed.
Children can also present with symptoms of chronic or recurrent sinusitis. These clinical symptoms may include
postnasal drainage or purulent anterior rhinorrhea, cough, fever, facial pain, and nasal congestion.
Additionally, children may have nasal airway obstructive symptoms without signs of acute or chronic infections.
The symptoms include nasal airway obstruction, snoring, and mouth breathing. When enlarged, the adenoid
blocks normal nasal cavity airflow and causes chronic mouth breathing, which can lead to palatal and dental
abnormalities
Indications
Indications for adenoidectomy are as follows:
Enlargement causing nasal airway obstruction, which can result in obstructive breathing, obstructive
sleep apnea symptoms, and chronic mouth breathing (could result in palatal and dental abnormalities)
Recurrent or persistent otitis media in children aged 3-4 years and older
Relevant Anatomy
The adenoid is on the posterior wall of the nasopharynx, which lies posterior to the nasal cavity. The adenoid
lies over the base of the skull and clivus area, shown below.
Drawing of a sagittal section of the nasal cavity, nasopharynx, oral cavity, palate, and oropharynx and of the location of the
tonsils and adenoids.
The adenoid overlies mucosa that overlies the superior constrictor muscle in this area. The adenoid can be
large enough to encroach on the posterior oropharyngeal wall. Lateral to the adenoid is the torus tubarius,
shown below, which is the medial orifice of the eustachian tube. The superior wall of the nasopharynx abuts the
choanae (ie, the posterior portion of the nasal cavity). The adenoid can be enlarged enough to obstruct the
choanae. The percentage of obstruction of the choanae is often used to size the adenoids.
A rigid rhinoscopy photograph taken all the way back into the choanae of the left nasal cavity. The photograph shows the
septum on the left, the small adenoids on the posterior superior wall of the nasopharynx in the center, and the eustachian
tube orifice on the right. This photograph is of the rigid rhinoscopy pathway down the nasal cavity of an infant aged 6 weeks.
Attached to the floor of the nose and choanae is the soft palate, depicted above. The soft palate is the anterior
inferior wall of the nasopharynx. The soft palate is responsible for regulating the amount of airflow into the
nasal cavity and nasopharynx from the oral cavity and oropharynx by opening and closing the posterior and
lateral nasopharyngeal wall, where the adenoid is housed. This sphincter of muscles is called the velopharynx.
The amount of airflow into the nasal cavity regulates the resonance of the voice. Too much airflow through the
nose results in hypernasal speech, and too little airflow results in hyponasal speech (seeVelopharyngeal
Insufficiency).
If the adenoid changes in size or is removed, the muscles of the palate must accommodate to a new gap size
to close off the nasopharynx. An inability of the velopharyngeal muscles to accommodate results in
velopharyngeal insufficiency (VPI).
For more information about the relevant anatomy, see Tonsil and Adenoid Anatomy.
No absolute contraindications exist, except for conditions in which general anesthesia cannot be performed.
Laboratory Studies
See the list below:
No standard preoperative laboratory evaluation exists for adenoidectomy. Most surgeons do not order
preoperative laboratory tests.
Intraoperatively, the adenoid can be sent for pathologic and histologic evaluation. It can also be sent
for culture to evaluate the pathogens present.
Imaging Studies
See the list below:
Normal lateral neck x-ray film evaluating the adenoids and nasopharynx.
Over the years, various dimensions in the nasal cavity and nasopharynx have been measured
to assess the degree of obstruction caused by adenoids, as shown below.
Different measurements for the choanae show (1) measurement of the adenoids, (2) horizontal measurement of the
nasopharyngeal stripe followed by horizontal measurement of the adenoid pad and diagonal thickness of the adenoid
pad, (3) horizontal measurement from the choanae to the adenoids and the adenoid pad, and (4) the thickness of the
palate in comparison to the thickness of the nasal pharyngeal air stripe.
Confusion related to the usefulness of the lateral neck radiograph and its capability to help
evaluate adenoid size is based partly on the 4 different techniques described.
The goal of all techniques is to correlate the measurements with the clinical efficacy of
adenoidectomy. Most techniques focus on the size of the nasopharyngeal stripe, which indicates the
amount of airflow through the nasopharynx. This measurement seems to be most accurate. When the
nasopharyngeal stripe is half the size of the soft palate, significant obstruction occurs. However, studies
indicate that improvement in rhinosinusitis symptoms or recurrent or persistent otitis media occurs as a
result of adenoidectomy, independent of the size of the adenoid. Thus, for those indications, knowing the
size of the adenoid preoperatively has no bearing on surgical judgment and is unnecessary.
CT scan
o
o
o
o
CT scan is not normally used to evaluate the adenoids. However, when a CT scan is
performed to evaluate the sinuses, the choana and nasopharynx are occasionally imaged, providing
information on the size of the adenoids.
If the CT scan does not involve the nasopharynx, information on the adenoids may be
obtained from the plain sagittal scout film performed along with the CT scan.
CT scan or MRI
If the adenoids look abnormal or if a mass is present in the nasopharynx in an older child or in
an adult, an imaging study (eg, CT scan, MRI) is obtained to rule out a lesion other than an adenoid.
The adenoids, by the time an individual is a teenager or older, usually regress in size and are
not usually causing an obstruction.
Diagnostic Procedures
Directa :
- With a view transoral directly into the soft palate in the nasopharynx after retraction .
- By anterior rhinoscopy see any upward movement of the soft palate time to say "i" is hampered by an
enlarged adenoids , it is called the soft palate negative phenomena
Indirecta :
- With a view mirrors and lamp head from the nasopharynx called rhinoscopy posterior oropharynx .
- With nasofaringioskop , a tool like scytoskop whose systems of lenses and prisms and light at one end ,
inserted through the cavity rice , whole nasopharynx can be seen
o
o
A rigid rhinoscopy photograph taken in the mid portion of the left nasal cavity showing the septum on the left, the inferior
turbinate on the right, and the middle turbinate superiorly. The choanae is seen in the dark area in the center. This
photograph is of the rigid rhinoscopy pathway down the nasal cavity of an infant aged 6 weeks.
A rigid rhinoscopy photograph taken two thirds of the way back along the floor of the nose of the left nasal cavity. This
photograph shows the septum on the left, the choanae straight ahead, and the posterior portion inferior turbinate to the
right. This photograph is of the rigid rhinoscopy pathway down the nasal cavity of an infant aged 6 weeks.
A rigid rhinoscopy photograph taken all the way back into the choanae of the left nasal cavity. The photograph shows the
septum on the left, the small adenoids on the posterior superior wall of the nasopharynx in the center, and the
eustachian tube orifice on the right. This photograph is of the rigid rhinoscopy pathway down the nasal cavity of an infant
aged 6 weeks.
Biopsy
o
o
o
o
Teenagers and adults may tolerate a biopsy of the nasopharyngeal mass with adequate
topical anesthesia in the clinic.
If any finding indicates that the lesion may be vascular, obtain preoperative imaging with a CT
scan, MRI, or magnetic resonance angiography and perform the biopsy in the operating room.
Histologic Findings
The adenoid is composed of lymphoid tissue, similar to a lymph node, without an afferent blood supply, as
shown below.
The adenoid has germinal centers where the antibodies are produced. See the images below. The epithelium
over the adenoid is the same as the respiratory epithelium in the nasal cavities and sinuses, which is a
pseudostratified, ciliated, columnar epithelium.
Close-up of adenoid histology showing immunological activities near the tonsillar crypt.
The immunological function of the adenoid has been studied by evaluating the types and numbers of different
immunological components, such as immunoglobulins (antibodies), antigen-presenting cells, neutrophils, and
dendritic cells. Additional function of the adenoid may be based on the ratio of respiratory to squamous
epithelium and the amount of functioning cilia present, which help nasal flow. All of these immunological and
protective functions are detrimentally affected by chronic infection in the adenoids
Staging
Adenoid size is often graded similarly to tonsil size as 1+, 2+, 3+, or 4+. This grading of the observed size of
the adenoid while the patient is in the supine position during surgery coordinates to 25%, 50%, 75%, or 100%
obstruction of the choana, respectively. Alternatively, the percentage of obstruction of the choana can be
mentioned and ranges from 0-100%. Remember that the degree or obstruction of the choana appears different
depending on if the adenoids are visualized while the patient is in the sitting position in the clinic or if the patient
is lying supine in the operating room with the palate reflected superiorly, depicted below.
A mirror is placed in the oral cavity and oropharynx, with the image on the mirror reflecting from the nasopharynx and
showing the adenoids in the center of the mirror, in front of the choanae, and in the center of the torus tubarius (opening of
the eustachian tubes) laterally. The red rubber catheter suspending the palate is shown as it passes through the choana
superiorly. This is a view of adenoids in the surgical position at the time of surgery.
A rigid rhinoscopy photograph in the right nasal cavity showing the adenoids at the center of the picture, appearing to almost
completely block the choanae. The child is in the upright position for the mirror image of the adenoids. Note that in this
position, the adenoids appear to almost completely block the choanae
Medical Therapy
No good evidence supports any curative medical therapy for chronic infection of the adenoids. Systemic
antibiotics have been used long-term (ie, 6 wk) for lymphoid tissue infection, but eradication of the bacteria
failed. In fact, with the current trend of resistant bacteria, the use of prophylactic or long-term antibiotics has
been decreased to prevent the formation of resistant bacteria.
Some studies indicate a benefit with using topical nasal steroids in children with adenoid hypertrophy. Studies
indicate that while using the medication, the adenoid may shrink slightly (ie, up to 10%), which may help relieve
some nasal obstruction. However, once the topical nasal steroid is discontinued, the adenoid can again
hypertrophy and continue to cause symptoms. In a child with nasal obstructive symptoms with or without
presumed allergic rhinitis, a trial of topical nasal steroid spray and saline spray may be considered for effective
control of symptoms.
Surgical Therapy
At this time, several surgical methods of removing the adenoid are available.
A mirror is placed in the oral cavity and oropharynx, with the image on the mirror reflecting from the nasopharynx and
showing the adenoids in the center of the mirror, in front of the choanae, and in the center of the torus tubarius (opening of
the eustachian tubes) laterally. The red rubber catheter suspending the palate is shown as it passes through the choana
superiorly. This is a view of adenoids in the surgical position at the time of surgery.
Different sizes of adenoid curettes, with the curette blade on the inside superior surface.
Long view of an adenoid curette, showing the entire length of the instrument.
Adenoid punch: An adenoid punch, shown below, is a curved instrument with a chamber that
is placed over the adenoids. The chamber is closed, and a knife blade surgically removes the adenoids,
which are then deposited in the chamber and removed with the instrument. Various sizes of instruments are
available for the various sizes of nasopharynges. Control hemostasis with packing and electrocautery.
Magill forceps: A Magill forceps, shown below, is a curved instrument used to remove residual
adenoid tissue, usually deep in the choana and encroaching on or into the posterior nasal cavity, after
attempted removal with curettes or adenoid punches.
Magill adenoid forceps used for the removal adenoids in the choanae that are jutting into the posterior nasal cavity,
which are difficult to reach.
Tip of a suction cautery instrument viewed from the end, with blue nonheat-transferring casing, silver metal cautery,
and center hollow tube for suctioning.
o
o
Some consider the pure coagulation setting time consuming. The chard adenoid tissue can
obstruct the suction, requiring repeated cleaning, which slows the procedure.
The coagulation/cutting combination method appears to be a quicker way to ablate the
adenoid tissue. However, when using the cutting method, the transfer of energy to the surrounding tissues
is greater, which can potentially cause more neck stiffness following the procedure.
Surgical microdebrider: Other surgeons have used the surgical microdebrider in this position (see
below). Some consider it equally or more effective. Bleeding certainly occurs during the actual removal, but
the total reported blood loss has been similar to using the traditional curette. The surgical microdebrider has
been advocated for removing adenoid tissue that is difficult to reach using other techniques. The additional
cost of the microdebrider setup and tip is also a consideration.
Different sizes of adenoid curettes, with the curette blade on the inside superior surface.
Laser: The Nd:YAG laser has been used for the resection of adenoids. This technique has caused
nasopharyngeal scarring and is best avoided.
Coblation: Many authors have described using coblation to ablate the adenoid tissue. It is effective but
may take increase time to remove the tissue, especially if significantly enlarged. The additional cost of the
coblator setup and tip is also a consideration
Complications
Complications following adenoidectomy are rare and are listed in the order of occurrence.
Bleeding
The first complication is immediate bleeding from the site, which occurs in 0.4% of cases. Some moderate
epistasis can be controlled with a vasoconstrictive agent (eg, oxymetazoline). Bleeding significant enough to
mandate a return to the operating room occurs in 4 in 1000 patients. Significant delayed bleeding, observed in
roughly 2% of tonsillectomy patients, is not observed with adenoidectomy.
Velopharyngeal insufficiency
VPI, observed in 0.03-0.06% of cases, occurs as a result of incomplete closure of the palate to the posterior
and lateral nasopharyngeal wall, where the adenoids had previously been located. VPI is observed transiently
in more than half the patients undergoing an adenoidectomy and usually resolves in 2-4 weeks. Persistent VPI
(ie, > 3 mo) occurs in 1 in 1500-3000 adenoidectomies. Persistent VPI occurs more often in children who have
generally decreased muscle tone or a known palatal abnormality (see Preoperative details). Some recommend
performing a partial adenoidectomy, leaving the inferior portion of the adenoid pad, in patients at high risk for
VPI. Treatment initially consists of speech therapy for as long as 12 months, depending on the severity of the
VPI. Surgery is required in 50% of persistent cases.
Torticollis
Because the adenoids are removed from the posterior wall of the nasopharynx over the spine and superior
constrictor muscle, children can have a stiff neck or spasm of the neck, occasionally with torticollis. Torticollis is
a rare occurrence. Warm compresses, a neck brace, and anti-inflammatory medications may be helpful for
relieving the spasm and pain.
Nasopharyngeal stenosis
Nasopharyngeal stenosis, which rarely occurs, consists of circumferential contracture of the pharynx in the
region of the Waldeyer ring. This contracture is more common with T&A than with adenoidectomy alone
because the combined procedure results in a larger and more circumferential area of denuded pharyngeal
surface with greater potential for scar contracture. The clinical presentation is usually nasal obstruction or
hyponasal speech. Repair usually consists of palatal or pharyngeal rotational flaps of unaffected mucosa and is
fraught with failure.
Chronic sinusitis
A study by Lee and Rosenfeld in 1997 showed that children with sinusitis improved after adenoidectomy, and
improvement was independent of the weight of the adenoids. [5] Other studies show that size is important to the
resolution of symptoms of sinusitis.
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