PATHOPHYSIOLOGY OF TYPE II DIABETES

MELLITUS
Beta Cells in the Pancreas produce insulin
(normal function)

Insulin binds with the receptors and glucose is absorbed

into the cell
(normal function)

Predisposing factors

Proper function of insulin is impaired

Precipitating Factors

lifestyle

genetics

hypertension

Obesity

age
Diagnosis: Type II
Diabetes Mellitus

Desensitization of insulin or insulin resistance

Compensation of Beta Cells

( it tends to produce more and more insulin)

Beta Cell burn out

Hyperglycemia

(glucose no longer effectively enter the cell, glucose re-enters blood stream
Blood Glucose Rises)