pressureis<90mmHg,orifmeanarterialpressureis

<70mmHg(9).Rapidperipheralintravenousaccessismandatory,notonlyforfluidresuscitationandcreationofa
routeformedicationtherapy,butalsoforcollectionthebloodsamplesinordertoassessSEetiology.
TheessentialdiagnosticworkupforSEincludesfingerstickglucosetesting,laboratorytesting(bloodglucose,
completebloodcount,liver/renalfunction,electrolytes,creatinephosphokinase,anddruglevelsforAEDs),and
head computed tomography (CT)scanning (especiallyforpatients withdenovoSE).Additionaltests that are
advisableforindividual SEpatients includemagneticresonance imaging(MRI)ofthehead, lumbar puncture,
toxicologyscreening,arterialbloodgastesting,andelectrocardiography (9).Iftheseizurepersistsdespiteaggressive
treatment,continuousEEGmonitoringisrecommended(9),especiallywhentheconvulsiveSEevolvesintosubtle
nonconvulsiveSE,orifpatientsundergocontinuousanesthesiatherapy.
Treatmentduringthefirststage:earlystatusepilepticus
ForrapidterminationofseizureactivityduringearlySE,benzodiazepinesaretheagentsofchoice,accordingto
expertopinionandtheresultsofafewclinicaltrials(8)\
g,orifmeanarterialpressureis
<70mmHg(9).Rapidperipheralintravenousaccessismandatory,notonlyforfluidresuscitationandcreationofarouteformedication
therapy,butalsoforcollectionthebloodsamplesinordertoassessSEetiology.
TheessentialdiagnosticworkupforSEincludesfingerstickglucosetesting,laboratorytesting(bloodglucose,completebloodcount,
liver/renalfunction,electrolytes,creatinephosphokinase,anddruglevelsforAEDs),andheadcomputedtomography(CT)scanning
(especiallyforpatientswithdenovoSE).AdditionalteststhatareadvisableforindividualSEpatientsincludemagneticresonance
imaging(MRI)ofthehead,lumbarpuncture,toxicologyscreening,arterialbloodgastesting,andelectrocardiography (9).Iftheseizure
persistsdespiteaggressivetreatment,continuousEEGmonitoringisrecommended (9),especiallywhentheconvulsiveSEevolvesinto
subtlenonconvulsiveSE,orifpatientsundergocontinuousanesthesiatherapy.
Treatmentduringthefirststage:earlystatusepilepticus
ForrapidterminationofseizureactivityduringearlySE,benzodiazepinesaretheagentsofchoice,accordingtoexpertopinionand
theresultsofafewclinicaltrials(8).
g,orifmeanarterialpressureis
<70mmHg(9).Rapidperipheralintravenousaccessismandatory,notonlyforfluidresuscitationandcreationofarouteformedication
therapy,butalsoforcollectionthebloodsamplesinordertoassessSEetiology.
TheessentialdiagnosticworkupforSEincludesfingerstickglucosetesting,laboratorytesting(bloodglucose,completebloodcount,
liver/renalfunction,electrolytes,creatinephosphokinase,anddruglevelsforAEDs),andheadcomputedtomography(CT)scanning
(especiallyforpatientswithdenovoSE).AdditionalteststhatareadvisableforindividualSEpatientsincludemagneticresonance
imaging(MRI)ofthehead,lumbarpuncture,toxicologyscreening,arterialbloodgastesting,andelectrocardiography (9).Iftheseizure
persistsdespiteaggressivetreatment,continuousEEGmonitoringisrecommended (9),especiallywhentheconvulsiveSEevolvesinto
subtlenonconvulsiveSE,orifpatientsundergocontinuousanesthesiatherapy.
Treatmentduringthefirststage:earlystatusepilepticus
ForrapidterminationofseizureactivityduringearlySE,benzodiazepinesaretheagentsofchoice,accordingtoexpertopinionand
theresultsofafewclinicaltrials(8).

g,orifmeanarterialpressureis
<70mmHg(9).Rapidperipheralintravenousaccessismandatory,notonlyforfluidresuscitationandcreationofarouteformedication
therapy,butalsoforcollectionthebloodsamplesinordertoassessSEetiology.
TheessentialdiagnosticworkupforSEincludesfingerstickglucosetesting,laboratorytesting(bloodglucose,completebloodcount,
liver/renalfunction,electrolytes,creatinephosphokinase,anddruglevelsforAEDs),andheadcomputedtomography(CT)scanning

(especiallyforpatientswithdenovoSE).AdditionalteststhatareadvisableforindividualSEpatientsincludemagneticresonance
imaging(MRI)ofthehead,lumbarpuncture,toxicologyscreening,arterialbloodgastesting,andelectrocardiography (9).Iftheseizure
persistsdespiteaggressivetreatment,continuousEEGmonitoringisrecommended (9),especiallywhentheconvulsiveSEevolvesinto
subtlenonconvulsiveSE,orifpatientsundergocontinuousanesthesiatherapy.
Treatmentduringthefirststage:earlystatusepilepticus
ForrapidterminationofseizureactivityduringearlySE,benzodiazepinesaretheagentsofchoice,accordingtoexpertopinionand
theresultsofafewclinicaltrials(8).
g,orifmeanarterialpressureis
<70mmHg(9).Rapidperipheralintravenousaccessismandatory,notonlyforfluidresuscitationandcreationofarouteformedication
therapy,butalsoforcollectionthebloodsamplesinordertoassessSEetiology.
TheessentialdiagnosticworkupforSEincludesfingerstickglucosetesting,laboratorytesting(bloodglucose,completebloodcount,
liver/renalfunction,electrolytes,creatinephosphokinase,anddruglevelsforAEDs),andheadcomputedtomography(CT)scanning
(especiallyforpatientswithdenovoSE).AdditionalteststhatareadvisableforindividualSEpatientsincludemagneticresonance
imaging(MRI)ofthehead,lumbarpuncture,toxicologyscreening,arterialbloodgastesting,andelectrocardiography (9).Iftheseizure
persistsdespiteaggressivetreatment,continuousEEGmonitoringisrecommended (9),especiallywhentheconvulsiveSEevolvesinto
subtlenonconvulsiveSE,orifpatientsundergocontinuousanesthesiatherapy.
Treatmentduringthefirststage:earlystatusepilepticus
ForrapidterminationofseizureactivityduringearlySE,benzodiazepinesaretheagentsofchoice,accordingtoexpertopinionand
theresultsofafewclinicaltrials(8).