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TESTING SOLUTIONS
Table of Contents
Selecting a Technique for Your Analysis............................... 3
Detection Limits......................................................................................3
Sample Throughput................................................................................4
Costs.......................................................................................................4
TESTING SOLUTIONS
Consumables..........................................................................................9
FOOD SAFETY
AND QUALITY
Flame AA
GFAA
ICP-OES
ICP-MS
Interferences
Ease-of-use
Availability of proven methodology
Flame AA
Detection Limits
The detection limits achievable for individual elements are
important in determining the usefulness of an analytical
technique for a given analytical problem. Without adequate
detection-limit capabilities, lengthy sample pre-concentration
procedures may be required prior to analysis.
Typical detection-limit ranges for the major atomic spectroscopy
techniques are shown in Figure 2. For a complete listing of
detection limits by element for Flame AA, GFAA, ICP-OES
(with radial and axial torch configurations) and ICP-MS, see
the table on page 6.
GFAA
ICP-MS
100
10
1
0.1
0.01
Detection Limit Ranges (ppb or g/L)
0.001
Figure 2. Typical detection limit ranges for the major atomic spectroscopy techniques.
Sample Throughput
Costs
GFAA
Hydride Generation AA
Flame AA
ICP-OES Axial View
ICP-OES Radial View
ICP-OES Dual View
ICP-MS
4 5 6 7 8 9 10
Orders of Magnitude of Signal Intensity
Figure 3. Typical analytical working ranges for the major atomic spectroscopy techniques.
Flame AA
GFAA
ICP-OES
ICP-MS
$0K
$50K
$100K
$150K
Typical complete system cost ($US)
$200K
GFAA
Graphite Furnace
Atomic Absorption
Spectroscopy
STRENGTHS
Very easy-to-use
Widely accepted
Limited analytical
working range
Single-element analytical
capability
Relatively inexpensive
ICP-OES
Inductively
Coupled Plasma
Optical Emission
Spectroscopy
LIMITATIONS
APPLICATIONS
SYSTEM
PinAAcle 900Z/H/T
AA Spectrometers
Optima ICP-OES
Spectrometers
Method development
more complex than other
techniques
NexION ICP-MS
Spectrometers
Table 2. Commonly used techniques for food safety and nutritional labeling analysis.
ATOMIC SPECTROSCOPY APPLICATIONS BY MARKET
MARKET
TYPICAL APPLICATIONS
AA
Food
ICP-OES
ICP-MS
Food safety
Nutritional labeling
FLAME AA
HG/HYDRIDE
GFAA
ICP-OES
ICP-MS
ELEMENT
FLAME AA
HG/HYDRIDE
GFAA
ICP-OES
ICP-MS
Ag
1.5
0.005
0.6
0.00009
Mo
45
0.03
0.5
0.00008
Al
45
0.1
0.0004 *
Na
0.3
0.005
0.5
0.0003
As
150
0.05
0.0004
Nb
1500
0.00004
Au
0.15
0.0001
Nd
1500
0.0003
1000
20
0.001
Ni
0.5
0.0002 *
Ba
15
0.35
0.03
0.00004
Os
0.00006
Be
1.5
0.008
0.09
0.0003
75000
130
0.04 *
Bi
30
0.05
0.00002
Pb
15
0.05
0.00004 *
0.04
Pd
30
0.09
0.00003
Pr
7500
0.00003
0.03
0.03
Br
C
0.07
Ca
1.5
0.01
0.05
0.0003 *
Pt
60
2.0
0.0001
Cd
0.8
0.002
0.1
0.00007
Rb
0.03
0.0002
1.5
0.00005
Re
750
0.5
0.0003
Rh
0.00004
100
0.0001
10
0.9 *
0.0002
0.1
0.001
0.05
0.0003 *
1.0
10
0.09
0.0002
Ce
Cl
Co
0.15
0.2
0.00006 *
Ru
Cr
0.004
0.2
0.0003 *
Cs
15
0.00005
Sb
45
Cu
1.5
0.4
0.0002 *
Sc
30
Dy
50
0.5
0.0002
Se
100
Er
60
0.5
0.0001
Si
90
Eu
30
0.2
0.00007
Sm
3000
Sn
150
0.1
0.0002
0.025
0.05
0.00007
0.014
F
Fe
Ga
0.06
1.0
0.15
0.03
0.05
0.1
0.0005 *
Sr
75
1.5
0.00008
Ta
1500
0.00001
Gd
1800
0.9
0.0003
Tb
900
0.00003
Ge
300
0.0006 *
Te
30
0.0003 *
Hf
300
0.5
0.0003
Th
0.00005
Hg
300
0.001
Ti
75
0.35
0.4
0.0002 *
Ho
60
0.4
0.00004
Tl
15
0.1
0.00001
0.003
Tm
15
0.6
0.00003
0.00008
15000
10
0.00002
0.5
0.00007 *
0.009
0.6
0.03
0.1
In
30
Ir
900
3.0
0.00009
60
0.005
0.001
1500
0.00003
La
3000
0.4
0.00004
75
0.2
0.00002
Li
0.8
0.3
0.00005
Yb
0.1
0.0001
Lu
1000
0.1
0.00004
Zn
1.5
0.2
0.0007 *
Mg
0.15
0.004
0.04
0.0001
Zr
450
0.5
0.00007
Mn
1.5
0.005
0.1
0.0001 *
0.06
0.1
0.02
All detection limits are given in micrograms per liter and were determined using elemental standards in dilute aqueous solution. All detection limits are based on a 98% confidence level
(three standard deviations).
All atomic absorption detection limits were determined using instrumental parameters optimized for the individual element, including the use of System 2 electrodeless discharge lamps
where available. Data shown were determined on a PerkinElmer AA.
All Optima ICP-OES detection limits were obtained under simultaneous multi-element conditions with the axial view of a dual-view plasma using a cyclonic spray chamber and a concentric
nebulizer.
Cold-vapor mercury detection limits were determined with a FIAS-100 or FIAS-400 flow injection system with amalgamation accessory.
The detection limit without an amalgamation accessory is 0.2 g/L with a hollow cathode lamp, 0.05 g/L with a System 2 electrodeless discharge lamp. (The Hg detection limit with the
dedicated FIMS-100 or FIMS-400 mercury analyzers is < 0.005 g/L without an amalgamation accessory and < 0.0002 g/L with an amalgamation accessory.) Hydride detection limits
shown were determined using an MHS-15 Mercury/Hydride system.
GFAA detection limits were determined on a PerkinElmer AA using 50 L sample volumes, an integrated platform and full STPF conditions. Graphite-furnace detection limits can be further
enhanced by the use of replicate injections.
All ICP-MS measurements were performed on a NexION ICP-MS with a quartz sample introduction system using a 3-second integration time and ten replicates in de-ionized water.
Detection limits were measured under multi-element conditions in Standard mode, except where denoted by an asterisk (*). Detection limits denoted by * were performed in a Class-100
Clean Room using Reaction mode with the most appropriate cell gas and conditions for that element in de-ionized water.
8
Consumables
With instruments that are the industry standard worldwide,
PerkinElmer accessories, consumables, methods and application
support meet the most demanding requirements and are the
preferred choice in thousands of laboratories globally.
We invest heavily in testing and validating our complete portfolio
of solutions to ensure that you receive accurate, repeatable
results, on-time, every time throughout the lifetime of your
instrument. From Lumina hollow cathode lamps that allow
automatic setup and provide long lamp lifetime to our Pure
Figure 9. 3D Scatterplot (top left), Data Table (top right), Treemap (bottom left),
Traceability Chart (bottom right).
Figure 10. 2D Scatterplots designed to show data above and below each contaminants
regulated limit.
10
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940 Winter Street
Waltham, MA 02451 USA
P: (800) 762-4000 or
(+1) 203-925-4602
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