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Biotechnology &
Biochemical Engineering
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Objectives:
 To encourages the students to work in the field of bio-chemical Industry.
The objective of this program is to introduce the basic concepts of bioprocessing to the chemical engineers.
Outcomes:
1.
Student will get well acquainted with intervention of chemical
engineering principles to biological process.
2.
Student will able to understand the concepts of enzyme
technology, immobilization technology, cell growth kinetics.
3.
Student will get knowledge of bioreactors, fermentation, sterilization
techniques, and media preparation.
4.
Student will get well acquainted with biological process specific reactor
design aspects.
5.
Student will get knowledge of downstream processing in fermentation
industries.

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Books
3

Biochemical Engineering fundamentals By


Bailey ollis
2. Bioprocess Engineering:-Basic concept by Shuler
& Kargi (PHI)
3. Biochemical Engineering:-principles & concepts
by Syed Tanveer Ahmed Inamdar(PHI)
4. Introduction to Biochemical Engineering by
D.G.Rao
1.

Introduction
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 Biotechnology : fusion of biology & technology


 Biological agents
 Production of useful products
 Biochemical engineering
 Application of chemical engineering principles to biological
systems
 Biologically derived products
 Scientific & engineering principle
 Biological agents(enzyme ,cell or microbes)

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Benefits of Biotechnology
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 Medicine
 Human
 Veterinary
 Biopharming
 Environment
 Agriculture
 Food products
 Industry and manufacturing

 Activities Involved in Bioprocess Industry


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CELL
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Cell- a discrete unit of life


Molecular biology- study of
molecules in cells
Cells as reactors
Metabolismprocesses
by
which organisms use nutrients
Catabolism- breaking down
materials
into
smaller
components
Anabolism- building
from smaller materials

tissues

Classification of Living Systems


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 Cell Type
 Plant, Animal & Protists (microorganisms)






Unicellular organism- organism of one cell


Multi-cellular organism- organism of many cells
Prokaryote- cells that lack specific nucleus
Eukaryote- cells with well-defined nucleus

 Classification of Protists

Prokaryotes
Eukaryotes

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Classification of living system


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Biocatalyst: cells and enzymes


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10-20 m

1-5 m

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Comparision
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Components of Cell
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 Proteins
 Nucleic Acid
 Lipids & Membranes
 Carbohydrates
 Cell wall

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Chemical composition of cells


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 Elemental composition
 C, H, N, P, O, S, Ash
 Molecular analysis
 Water, Protein, Nucleic Acid, Lipid, Population in culture, dry
wt in culture

The Hierarchy of biological


structure

Cells are building


blocks:
Tissue- collection of
cells with specific
functions
Organs- collections of
tissues with specific
functions
Organ systemscollections of organs
with specific functions

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Biochemical Components
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 Proteins
 Carbohydrates
 lipids & Fats
 nucleic acid
 Enzymes

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