Professional Documents
Culture Documents
lentigo maligna (melanoma-in-situ frequently on the face and arms of the elderly)
melanoma-in-situ
Any of the above types may produce melanin (and be dark in colour) or not (and be
amelanotic - not dark). Similarly any subtype may show desmoplasia (dense fibrous reaction
with neurotropism) which is a marker of aggressive behaviour and a tendency to local
recurrence.
Elsewhere:
uveal melanoma
prognosis. Metastases to brain, bone and liver are associated with a worse
prognosis.
People with metastatic melanoma may not feel like eating especially if they are
uncomfortable or tired. Foods may taste different than they did previously. Poor
appetite, nausea, or vomiting are all side-effects of melanoma. Good nutrition
however often helps people with cancer feel better and have more energy. [69]
However, only a small percentage of melanoma diagnosed yearly are metastatic.
Waiting for these symptoms to appear before seeking professional exam is not
recommended.
Treatment =
Surgery - Complete surgical excision with adequate margins and assessment for
the presence of detectable metastatic disease along with short- and long-term
followup is standard. Often this is done by a "wide local excision" (WLE) with 1 to
2 cm margins.