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Iso-alcoholic Elixir
Materials:
*glycerin, sucrose, (sorbitol) sweetening
agents
*alcohol excellent solvent for drugs but
has an unpleasant taste (need flavorant)
Substitution for glycerin and alcohol
propylene glycol
Elixirs hydroalcoholic (alcohol + H2O)
oral solutions that are clear, sweetened and
usually flavored to improve their taste.
-
alcoholic/hydroalcoholic
solutions of aromatic or volatile
material
high alcoholic conc. (usually over
60%) is due to greater solubility of
the volatile ingredient in alcohol
rather than in water
active ingredient contained in spirit
may be solid, liquid, or gas
used as flavoring agent or for its
medicinal value
can be applies externally, inhaled, or
taken internally
diluting the spirit with water before
oral intake reduces its pungent taste
can be prepared by: simple solution
(solutes are dissolved in solvent),
solution by maceration ( leaves are
soaked in alcohol to extract desired
volatile substance) and distillation
(takes advantage of the process of
fermentation: sugar in the raw
material is consumed by the added
yeast resulting to the formation of
alcohol)
USP specification: each 100 ml of
compound orange spirit contains nlt
25 ml and nmt 30 ml of the mixed
oils
Distillation
Fermentation
Brandy fermented grapes