Professional Documents
Culture Documents
DOI 10.1007/s00420-012-0791-3
ORIGINAL ARTICLE
Received: 13 July 2011 / Accepted: 18 June 2012 / Published online: 4 July 2012
Springer-Verlag 2012
Abstract
Purpose The psychosocial work environment may be a
determinant of the development and course of depressive
disorders, but the literature shows inconsistent findings.
Thus, the aim of this study is to determine longitudinal
effects of the job demandscontrolsupport model
(JDCSM) variables on the occurrence of major depression
among working men and women from the general
population.
Methods The sample comprised 4,710 working women
and men living in Stockholm, who answered the same
questionnaire twice, 3 years apart, who were not depressed
during the first wave and had the same job in both waves.
The questionnaire included JDCSM variables (demands,
skill discretion, decision authority and social climate) and
other co-variables (income, education, occupational group,
social support, help and small children at home, living with
an adult and depressive symptoms at time 1; and negative
life events at time 2). Multiple logistic regressions were run
to calculate odds ratios of having major depression at time
2, after adjustment for other JDCSM variables and covariables.
A. Fandino-Losada (&) Y. Forsell
Division of Public Health Epidemiology, Department of Public
Health Sciences, Karolinska Institutet, Norrbacka, Plan 7,
Karolinska Hospital, 171 73 Stockholm, Sweden
e-mail: andres.fandino@ki.se; fandino.andres@gmail.com
A. Fandino-Losada
School of Public Health/CISALVA Institute,
Universidad del Valle, Cali, Colombia
I. Lundberg
Department of Medical Sciences,
Occupational and Environmental Medicine,
Uppsala Universitet, Uppsala, Sweden
Introduction
The psychosocial work environment can be an important
determinant of the development and course of depressive
disorders (for reviews, see Stansfeld and Candy 2006;
Bonde 2008; Netterstrm et al. 2008). There are different
models to describe this environment, but the job demands
control(support) model (JDCSM) has been the most
influential since its appearance in the late 1970s. The
JDCSM involves two logical and easily understandable
concepts: job demands and job control (or decision latitude). Job demands refer to task requirements and work
load. Job control refers to individuals ability to control
their work activities. Furthermore, Karasek emphasised
that both demands and control determine the psychological
strain at work, and job strain was defined as the combination of high demands and low control (Karasek 1979).
123
592
123
Methods
Population and sample
The study sample was drawn from the PART studya
longitudinal study of mental health, work and relations
ongoing in Stockholm County, Sweden. The study population at wave 1 included 19,744 individuals aged
2064 years registered in the county and randomly selected
from the county council register. The ethical committee at
the Karolinska Institutet, Stockholm, approved the study,
and informed consents were obtained from all participants.
Wave 1 (19982000)
(Time 1: T1). Subjects in the intended population sample
received a questionnaire by mail, and 10,443 individuals
responded (53 % of the intended sample). An extensive
non-response analysis was done by using available official
registers. Participation was related to female gender, higher
age, higher income and education, being born in the Nordic
countries, and having no psychiatric diagnosis in the hospital discharge register or in the early retirement register.
Associations between age, gender, income, country of
origin and inpatient hospital care due to psychiatric diagnosis were calculated for participants and non-participants
separately. The odds ratios (ORs) for these associations
were very similar among participants and non-participants
(Lundberg et al. 2005).
Wave 2 (20012003)
(Time 2: T2). All participants from the first wave received a
second, almost identical, questionnaire 3 years later. The
participation rate at the follow-up phase (T2) was 83 %
(n = 8,622). Attrition in the second phase was associated
with the same conditions as in the first phase, but associations
between putative risk factors and major depression, determined at T1, were the same in both the T2-participant and
T2-non-participant subsamples (Bergman et al. 2010).
Additionally, participants diagnosed with major depression
at time 1 had a higher probability of non-participation at time
2 (OR = 1.6; 95 % confidence interval (CI) = 1.12.4).
593
123
594
Confounders
Statistical analyses
In this study, the following variables were selected as
potential confounders in multivariable regression models,
because they have been associated with both depressive
disorders and psychosocial work factors in several studies:
age, living without another adult, little help with household
chores, small children at home, education level, income
level, occupational groups, inadequate availability of social
attachment (as a continuous score), depressive symptoms at
baseline (T1), also as a continuous score and the number of
potentially negative life events at T2 (Muntaner et al. 1998;
Griffin et al. 2002; Michelsen and Bildt 2003; Mitchell et al.
2003; Bonde 2008; Choi and Marks 2008; Netterstrm et al.
123
In this paper, the JDSCM scales on job demands, inadequate job skill discretion, inadequate job decision authority
and inadequate work social climate were split by cut-off
points defined by scale-specific quartiles obtained from the
current study sample, that is, subjects without major
depression at T1 according to the MDI algorithm and who
had the same job at both waves. Thus, sample distribution
quartiles, independently for each JDCSM variable, were
used for defining the exposure groups (i.e. exposure categories grouping scores of JDCSM scales). Due to the
limited number of scale points, the scales could not be
divided into exact medians or quartiles. The true percentages by intended quartiles and median are shown in
Tables 1, 2, 3 and 4. Median split exposure groups were
defined merging the two lowest (Q1 and Q2) and the two
highest (Q3 and Q4), respectively. The quartile and median
cut-off scores for defining the JDCSM exposure groups are
shown in Tables 1, 2 and 3 for the quartile splits and
Table 4 for the median splits. The JDCSM quartiles
resulted in percentages different to the theoretical 25 % in
each one, given the empirical distribution of scales scores;
for example, for job demands, a 12-point score was not
only the 25th percentile but also the 35th percentile. There
were not significant differences in cut-offs between women
and men for the JDCSM dimensions; thus, the same divisions were used for generating the exposure categories in
Tables 1 (womens results) and 2 (mens results).
Nearly eleven per cent (10.64 %) of the subjects records
had at least one variable with missing values; thus, the
regression imputation method (Raghunathan 2004; Donders
et al. 2006; Groves et al. 2009) was used to complete the
missing values in exposure variables and confounders before
running the regression models. For testing the robustness of
results from these models, all regressions were repeated
without imputed values. Initially, cross-tabulations and single-regression analyses were done to explore associations
between the outcome variable and exposures and confounders using the crude data (Tables 1, 2). Then, regression
analyses followed this sequence: firstly, exposure categories
(quartiles of JDCSM variables) were used in block enter
logistic regressions, starting with the simplest logistic
regression models (only one JDCSM variable) with occurrence of major depression at T2 as the outcome, using the
lowest quartile as the reference group for each variable.
These regression models were called Model 0, that is, the
unadjusted ones. Afterwards, multiple logistic regressions
were run to calculate the ORs of having the outcome (i.e.
major depression) at follow-up (T2) for each psychosocial
work environment variable quartiles compared with the
reference quartile, adding the confounding variables in each
step. In this manner, Model 1 adjusted for all JDCSM variables (i.e. job demands, skill discretion, decision authority
and job social climate) and age. Model 2 included Model 1
variables and additionally adjusted for living alone status,
inadequate social availability (scale score), having little help
with household chores, having small children at home and
number of negative life events at T2. Model 3 included
Model 2 variables and additionally adjusted for education
level, income level and occupational groups. Model 4
included Model 3 variables and additionally adjusted for
depressive symptoms score (MDI) at T1.
Model 4 could be considered an over-adjusted regression model, because it is controversial whether a high level
of baseline depressive symptoms (T1) was a confounder or
595
Results
The point prevalence of major depression at the third year
follow-up (T2) was 3.77 % (95 % CI = 3.214.33 %),
being 5.63 % (95 % CI = 4.716.55 %) among women
and 1.54 % (95 % CI = 1.002.08 %) among men, based
on 136 cases among women and 31 cases among men.
Tables 1 and 2 describe the distribution of the JDCSM
variables and the selected confounders among cases and noncases for each gender (Tables 1 and 2, respectively). Among
women, the cases tended to have higher job demands, lower
job skill discretion and lower job social climate, to receive
less help with household chores, to have lower education and
income levels, to belong to the unskilled manual (blue collar)
workers, to the lower non-manual (white collar) workers or
to the entrepreneurs, to be younger, to have lower availability
of social attachment, to have higher levels of depressive
symptoms at T1 and to have experienced more negative life
events (one, two or three or more categories) at T2 when
compared with controls (Table 1). For men, the cases tended
to have lower job demands, lower job skill discretion, lower
job decision authority and lower job social climate, to live
without other adults, to receive less help with household
chores, to have lower income levels, to belong to the skilled
manual (blue collar) workers or to the lower non-manual
(white collar) workers, to have lower availability of social
attachment and to have higher levels of depressive symptoms
at T1 and to have experienced more negative life events (one,
two or three or more categories) at T2 when compared with
the controls (Table 2).
123
596
Table 1 Crude associations between study variables at time 1 and major depression at time 2 for women
Exposure variables
Depressed T2
N = 136
Non-depressed T2
N = 2,279
Crude ORs
Na
Na
OR
39
29.6
850
37.7
20
32
15.2
24.2
310
539
13.8
23.9
1.41
1.29
(0.812.45)
(0.802.09)
41
31.1
555
24.6
1.61*
(1.032.53)
38
27.9
728
32.1
Low (7 points)
30
22.1
432
19.0
1.33
(0.812.18)
34
25.0
739
32.6
0.88
(0.551.42)
34
25.0
370
16.3
1.76*
(1.092.84)
Lowest (2 points)c
39
28.7
693
30.5
Low (3 points)
18
13.2
483
21.2
0.66
(0.371.17)
High (4 points)
37
27.2
528
23.2
1.25
(0.781.98)
42
30.9
572
25.1
1.30
(0.832.05)
(95 % CI)
22
17.2
760
35.4
29
36
22.7
28.1
462
569
21.5
26.5
2.17**
2.19**
(1.233.82)
(1.273.76)
41
32.0
356
16.6
3.98***
(2.336.78)
37
27.2
630
27.7
0.98
(0.661.44)
72
53.3
954
42.1
1.57*
(1.112.23)
31
22.8
393
17.3
1.41
(0.932.13)
10
7.3
760
33.4
One
25
18.4
678
29.8
2.80**
(1.345.88)
Two
28
20.6
439
19.3
4.85***
(2.3310.07)
Three or more
73
53.7
400
17.5
13.87***
(7.0827.16)
Education level T1
9 years or less
24
17.7
303
13.3
1.84*
(1.113.04)
1011 years
62
45.6
813
35.7
1.77**
(1.212.59)
12 years or morec
50
36.8
1159
51.0
15
18
11.0
13.2
153
255
6.7
11.2
2.05*
1.48
(1.143.69)
(0.862.53)
(1.032.34)
39
28.7
526
23.1
1.55*
64
47.1
1339
58.9
18
14.1
243
11.2
1.87
(0.933.81)
6.2
111
5.1
1.84
(0.764.44)
Occupational groups T1
Unskilled manual workers
Skilled manual workers
Lower non-manual workers
39
30.5
459
21.1
2.16*
(1.173.99)
32
25.0
672
30.9
1.21
(0.652.27)
15
11.7
382
17.6
Self-employed professionals
Entrepreneurs
123
4.7
183
8.4
0.83
(0.322.19)
10
7.8
121
5.6
2.10
(0.924.81)
597
Table 1 continued
Continuous variables T1
Mean
SD
Mean
SD
Age
40.43
10.54
42.58
10.95
0.98*
(0.971.00)
4.72
1.81
4.02
1.28
1.34***
(1.211.48)
10.82
6.76
5.50
5.26
1.14***
(1.111.17)
OR
(95 % CI)
Significance level at p \ 0.10; * Significance level at p \ 0.05; ** Significance level at p \ 0.01; *** Significance level at p \ 0.001
quartiles split,
reference category,
Discussion
The literature shows inconsistent results for the longitudinal relationships between JDCSM variables and depressive
disorders, but two recent meta-analyses and a systematic review (Stansfeld and Candy 2006; Bonde 2008;
Netterstrm et al. 2008) showed coherent results on high
job demands and low occupational social support as risk
factors for subsequent major depressive disorders or mental
illness occurrence. In contrast, these reviews showed contradictory results regarding job control, or its components,
as risk or protective factors for major depression. The
findings about major depression in these reviews were
based on small number of papers for each JDCSM
dimension. In our study, the findings regarding inadequate
job social climate are in line with the current evidence and
show that, in particular, a good social climate seems protective against major depression among women, but our
123
598
Table 2 Crude associations between study variables at time 1 and major depression at time 2 for men
Exposure variables
Depressed T2
N = 31
Non-depressed T2
N = 1,981
Na
16
53.3
4
3
13.3
10.0
Na
Crude ORs
%
OR
(95 % CI)
722
36.7
273
546
13.9
27.7
0.66
0.25*
(0.222.00)
(0.070.86)
23.3
428
21.7
0.74
(0.301.81)
14
45.2
819
41.6
Low (7 points)
19.4
372
18.9
0.94
(0.362.47)
9.7
566
28.7
0.31
(0.091.08)
25.8
213
10.8
2.20
(0.915.31)
22.6
782
39.5
Low (3 points)
29.0
466
23.5
2.16
High (4 points)
16.1
407
20.6
1.37
(0.434.35)
10
32.3
325
16.4
3.44*
(1.309.11)
(0.805.83)
24.1
611
34.5
5
6
17.2
20.7
429
470
24.2
26.6
1.02
1.11
(0.323.23)
(0.373.34)
11
37.9
260
14.7
3.69**
(1.429.63)
13
41.9
450
22.8
2.45*
(1.195.04)
21
70.0
873
44.3
2.93**
(1.346.44)
29.0
343
17.4
1.94
(0.894.26)
3.3
753
38.0
One
20.0
575
29.1
7.86
(0.9465.45)
Two
20.0
360
18.2
12.55*
(1.51104.63)
17
56.7
291
14.7
43.99***
(5.83332.05)
Three or more
Education level T1
9 years or less
16.1
236
11.9
1.49
(0.534.22)
1011 years
13
41.9
827
41.8
1.11
(0.512.40)
12 years or morec
13
41.9
915
46.3
2
5
6.5
16.1
90
142
4.6
7.2
2.75
4.36**
(0.6012.61)
(1.4912.73)
(1.879.46)
200299 K SEK
13
41.9
383
19.4
4.21***
11
35.5
1363
68.9
10.0
197
10.2
2.17
(0.4310.86)
16.7
203
10.5
3.51
(0.8314.85)
16.7
182
9.4
3.92
(0.93-16.57)
23.3
412
21.4
2.42
(0.629.44)
10.0
428
22.2
Occupational groups T1
Self-employed professionals
13.3
264
13.7
2.16
(0.489.73)
Entrepreneurs
10.0
243
12.6
1.76
(0.358.79)
123
599
Table 2 continued
Continuous variables T1
Mean
Age
Inadequate social availability
Depressive symptoms score
SD
Mean
SD
OR
(95 % CI)
40.65
8.60
43.18
11.00
0.98
(0.951.01)
5.45
2.20
4.39
1.55
1.37***
(1.151.62)
12.03
5.43
4.18
4.45
1.23***
(1.171.29)
Significance level at p \ 0.10; * Significance level at p \ 0.05; ** Significance level at p \ 0.01; *** Significance level at p \ 0.001
quartiles split,
reference category,
Table 3 Adjusted multiple logistic regression models for major depression at T2 among women
Outcome: major
depression at T2
Quartiles split of
Model 0
OR
Model 1
(95 % CI)
OR
Model 2
(95 % CI)
OR
Model 3
(95 % CI)
OR
Model 4
(95 % CI)
OR
(95 % CI)
1.41
1.33
(0.812.46)
(0.832.14)
1.36
1.21
(0.772.40)
(0.741.98)
1.23
1.01
(0.682.21)
(0.601.68)
1.21
0.99
(0.672.20)
(0.591.67)
1.23
0.94
(0.672.26)
(0.551.59)
1.69*
(1.082.64)
1.33
(0.832.13)
1.19
(0.731.94)
1.31
(0.792.15)
1.07
(0.641.79)
Low (7 points)
1.29
(0.782.12)
1.29
(0.782.14)
1.28
(0.762.16)
1.18
(0.692.02)
1.13
(0.651.95)
0.88
(0.551.42)
0.86
(0.531.42)
0.79
(0.471.32)
0.63
(0.371.08)
0.65
(0.371.13)
1.75*
(1.092.83)
1.63
(0.962.77)
1.57
(0.912.74)
1.12
(0.612.05)
1.12
(0.602.10)
Lowest (2 points)b
Low (3 points)
0.65
(0.371.15)
0.57
(0.321.01)
0.58
(0.321.05)
0.61
(0.331.11)
0.63
High (4 points)
1.23
(0.771.95)
1.00
(0.621.62)
1.08
(0.651.78)
1.05
(0.621.76)
1.02
(0.601.76)
1.25
(0.801.97)
0.79
(0.481.31)
0.82
(0.491.38)
0.75
(0.441.30)
0.74
(0.421.30)
1
(0.341.17)
2.32**
2.42***
(1.334.05)
(1.424.13)
2.35**
2.41**
(1.344.14)
(1.404.16)
1.97*
1.92*
(1.103.52)
(1.093.38)
2.08*
2.08*
(1.153.75)
(1.183.68)
2.09*
1.85*
(1.153.81)
(1.033.31)
4.19***
(2.477.11)
3.84***
(2.206.71)
2.55**
(1.424.56)
2.78***
(1.535.06)
2.06*
(1.103.83)
Model 0: Simple logistic regression, that is, unadjusted by each other JDCSM variable
Model 1: Adjusted for each other JDCSM variables (i.e. job demands, skill discretion, decision authority and job social climate) and age at T1
Model 2: Model 1 and additionally adjusting for living alone status, inadequate social availability (scale score), having little help with home
chores and having small children at home at T1, and negative life events at T2
Model 3: Model 2 and additionally adjusting for education level, income level and occupational groups at T1
Model 4: Model 3 and additionally adjusting for score of depressive symptoms (MDI) at T1
OR odds ratio, CI confidence interval
Significance level at p \ 0.10; * Significance level at p \ 0.05; ** Significance level at p \ 0.01; *** Significance level at p \ 0.001
a
quartiles split,
reference category
123
600
Table 4 Adjusted multiple logistic regression models for major depression at T2 among men
Outcome: major
depression at T2
Median split of:
Model 0
OR
Model 1
(95 % CI)
OR
Model 2
(95 % CI)
OR
Model 3
(95 % CI)
OR
Model 4
(95 % CI)
OR
(95 % CI)
0.49
1
(0.231.04)
0.41*
1
(0.190.88)
0.33**
(0.140.73)
0.23**
1
(0.090.57)
0.24**
(0.100.60)
0.84
1.60
(0.401.76)
0.58
1
(0.271.27)
0.50
(0.221.15)
0.30*
1
(0.110.79)
0.32*
(0.110.90)
1
(0.793.25)
1.44
1
(0.683.08)
1.20
(0.532.72)
0.91
1
(0.372.27)
0.82
(0.322.07)
2.03
(0.994.16)
2.37*
1
(1.125.02)
1.84
(0.814.18)
1.54
1
(0.633.78)
1.40
(0.563.48)
Model 0: Simple logistic regression, that is, unadjusted by each other JDCSM variable
Model 1: Adjusted for each other JDCSM variables (i.e. job demands, skill discretion, decision authority and job social climate) and age at T1
Model 2: Model 1 and additionally adjusting for living alone status, inadequate social availability (scale score), having little help with home
chores and having small children at home at T1, and negative life events at T2
Model 3: Model 2 and additionally adjusting for education level, income level and occupational groups at T1
Model 4: Model 3 and additionally adjusting for score of depressive symptoms (MDI) at T1
OR odds ratio, CI confidence interval
Significance level at p \ 0.10; * Significance level at p \ 0.05; ** Significance level at p \ 0.01; *** Significance level at p \ 0.001
Median split,
reference category
123
2006). Adding more empirical evidence to this controversy, we found a protective effect of inadequate skill
discretion on the occurrence of major depression, but only
among men. Such findings have been obtained before
(Kawakami et al. 1995; Kondo et al. 2006). A possible
explanation for these peculiar results is that using skills has
become more of a demand when work intensity increases
(Joensuu et al. 2010). Furthermore, we stratified the mens
analyses by three major occupational groups (blue-collar
workers, white-collar workers and other workers) in order
to test the robustness of this protective effect among different occupational groups. Thus, the OR of low skill
discretion remained significantly protective only in the
blue-collar strata (data not shown); however, the ORs for
low skill discretion in the other two strata were also below
unity. Additionally, our findings strongly suggest that skill
discretion and decision authority should be addressed
separately in future studies about the psychosocial work
environment.
Finally, inadequate social climate at work appeared as a
predictor of major depression only among women, and it
remained significant over different adjusted models. Trend
analyses showed a significant linear trend over the quartiles
of inadequate social climate with the reference category
significantly lower than the upper three categories. Our
results confirm findings about inadequate social climate as
a risk factor for depressive disorders in other longitudinal
studies (Bonde 2008; Sinokki et al. 2009), but our genderspecific findings were opposite to those reported in the
literature, where inadequate social support at work was a
stronger risk factor among men than among women
(Griffin et al. 2002; Shields 2006; Netterstrm et al. 2008)
or only significant among men, when the outcome was use
of antidepressant medication (Thielen et al. 2011). The
limited number of men with major depression in our
sample (only 31 subjects) should have implied a low power
to detect significant relationships. Additionally, our measure of social climate did not cover instrumental social
support. It is possible that inadequate social climate could
have a stronger relation with major depression among
women than among men while inadequate instrumental
social support, which we have not measured, could be more
related to major depression among men.
Limitations of the study
First, our sample of working individuals was plausibly
comprised by individuals healthier in terms of their physical and mental health than those unemployed or not in the
labour market (i.e. the healthy worker effect), which is in
line with the patterns of participation in both waves of the
PART study (Lundberg et al. 2005; Bergman et al. 2010);
thus, the occurrence of major depression in our study was
601
123
602
123
Conclusions
The results showed that a good work social climate was
protective against major depression among women. However, there were no clear effects of other JDCSM exposure
variables among women. Among men, high job demands
and low skill discretion appeared as protective factors
against major depression; both are novel and controversial
findings considering the recent literature reviews. Thus,
more studies are warranted to disentangle such relationships. Finally, decision authority and skill discretion
seemed to have opposite effects on the occurrence of major
depression; therefore, they should be addressed separately
in future studies about the psychosocial work environment.
Acknowledgments The authors thank the PART project grant
providers: the Swedish Medical Research Council, the Swedish
Council for Working Life and Social Research and the Stockholm
County Council (Grant number VR K2007-61X-20381-01-3). The
PhD student support was provided by the COLFUTURO Foundation
(Colombia), the ERACOL academic exchange programme (Erasmus
Mundus External CooperationEurope) and Universidad del Valle
(Colombia). We also wish to thank Professor Tores Theorell for
valuable suggestions during the development of the study, Peeter
Fredlund and Michael Lundberg for statistical advice and the
Reviewers for suggestions for improving the manuscript.
Conflict of interest
of interest.
References
Ahlberg-Hulten GK, Theorell T, Sigala F (1995) Social support, job
strain and musculoskeletal pain among female health care
personnel. Scand J Work Environ Health 21(6):435439
Ahola K, Hakanen J (2007) Job strain, burnout, and depressive
symptoms: a prospective study among dentists. J Affect Disord
104(13):103110
603
Griffin JM, Greiner BA, Stansfeld SA, Marmot M (2007) The effect
of self-reported and observed job conditions on depression and
anxiety symptoms: a comparison of theoretical models. J Occup
Health Psychol 12(4):334349
Groves RM, Fowler FJ, Couper MP, Lepkowski JM, Singer E (2009)
Survey methodology, 2nd edn. Wiley, Hoboken
Haahr J, Frost P, Andersen J (2007) Predictors of health related job
loss: a two-year follow-up study in a general working population. J Occup Rehabil 17(4):581592
Hallstrom T, Damstrom Thakker K, Forsell Y, Lundberg I, Tinghog P
(2003) The PART study. A population based study of mental
health in the Stockholm County: study design. Phase l
(19982000). Report, Samhallsmedicin, Sweden
Henderson S, Duncan-Jones P, Byrne DG, Scott R (1980) Measuring
social relationships. The interview schedule for social interaction. Psychol Med 10(4):723734
Hernan MA, Hernandez-Daz S, Werler MM, Mitchell AA (2002)
Causal knowledge as a prerequisite for confounding evaluation:
an application to birth defects epidemiology. Am J Epidemiol
155(2):176184
Joensuu M, Vaananen A, Koskinen A, Kivimaki M, Virtanen M,
Vahtera J (2010) Psychosocial work environment and hospital
admissions due to mental disorders: a 15-year prospective study
of industrial employees. J Affect Disord 124(12):118125
Johnson JV, Hall EM (1988) Job strain, work place social support,
and cardiovascular disease: a cross-sectional study of a random
sample of the Swedish working population. Am J Public Health
78(10):13361342
Johnson JV, Hall EM, Theorell T (1989) Combined effects of job
strain and social isolation on cardiovascular disease morbidity
and mortality in a random sample of the Swedish male working
population. Scand J Work Environ Health 15(4):271279
Jurado D, Gurpegui M, Moreno O, Fernandez MC, Luna JD, Galvez
R (2005) Association of personality and work conditions with
depressive symptoms. Eur Psychiatry 20(3):213222
Kaikkonen R, Rahkonen O, Lallukka T, Lahelma E (2009) Physical
and psychosocial working conditions as explanations for occupational class inequalities in self-rated health. Eur J Public
Health 19(5):458463
Karasek RA (1979) Job demands, job decision latitude, and mental
strainimplications for job redesign. Adm Sci Q 24(2):285
308
Karasek R, Theorell T (1990) Healthy work: stress productivity and
the reconstruction of working life. Basic Books, New York
Karasek R, Brisson C, Kawakami N, Houtman I, Bongers P, Amick B
(1998) The job content questionnaire (JCQ): an instrument for
internationally comparative assessments of psychosocial job
characteristics. J Occup Health Psychol 3(4):322355
Kasl SV (1998) Measuring job stressors and studying the health
impact of the work environment: an epidemiologic commentary.
J Occup Health Psychol 3(4):390401
Kawakami N, Roberts RE, Lee ES, Araki S (1995) Changes in rates
of depressive symptoms in a Japanese working population: lifetable analysis from a 4-year follow-up study. Psychol Med
25(06):11811190
Kondo K, Kobayashi Y, Hirokawa K, Tsutsumi A, Kobayashi F,
Haratani T, Araki S, Kawakami N (2006) Job strain and sick
leave among Japanese employees: a longitudinal study. Int Arch
Occup Environ Health 79(3):213219
Kristensen TS (1996) Job stress and cardiovascular disease: a
theoretic critical review. J Occup Health Psychol 1(3):246260
Landsbergis P, Theorell T, Schwartz J, Greiner BA, Krause N (2000)
Measurement of psychosocial workplace exposure variables.
Occup Med 15(1):163188
Lerner D, Adler DA, Chang H, Lapitsky L, Hood MY, Perissinotto C,
Reed J, McLaughlin TJ, Berndt ER, Rogers WH (2004)
123
604
Unemployment, job retention, and productivity loss among
employees with depression. Psychiatr Serv 55(12):13711378
Lundberg I, Damstrom Thakker K, Hallstrom T, Forsell Y (2005)
Determinants of non-participation, and the effects of nonparticipation on potential cause-effect relationships, in the PART
study on mental disorders. Soc Psychiatry Psychiatr Epidemiol
40(6):475483
MacCallum RC, Zhang S, Preacher KJ, Rucker DD (2002) On the
practice of dichotomization of quantitative variables. Psychol
Methods 7(1):1940
Magnusson Hanson L, Theorell T, Bech P, Rugulies R, Burr H, Hyde
M, Oxenstierna G, Westerlund H (2009) Psychosocial working
conditions and depressive symptoms among Swedish employees.
Int Arch Occup Environ Health 82(8):951960
Michelsen H, Bildt C (2003) Psychosocial conditions on and off the
job and psychological ill health: depressive symptoms, impaired
psychological wellbeing, heavy consumption of alcohol. Occup
Environ Med 60(7):489496
Mitchell PB, Parker GB, Gladstone GL, Wilhelm K, Austin M-PV
(2003) Severity of stressful life events in first and subsequent
episodes of depression: the relevance of depressive subtype.
J Affect Disord 73(3):245252
Muntaner C, Eaton WW, Diala C, Kessler RC, Sorlie PD (1998)
Social class, assets, organizational control and the prevalence of
common groups of psychiatric disorders. Soc Sci Med
47(12):20432053
Netterstrm B, Conrad N, Bech P, Fink P, Olsen O, Rugulies R,
Stansfeld S (2008) The relation between work-related psychosocial factors and the development of depression. Epidemiol Rev
30(1):118132
Niedhammer I, Goldberg M, Leclerc A, Bugel I, David S (1998)
Psychosocial factors at work and subsequent depressive symptoms in the Gazel cohort. Scand J Work Environ Health
24(3):197205
Olsen LR, Jensen DV, Noerholm V, Martiny K, Bech P (2003) The
internal and external validity of the major depression inventory
in measuring severity of depressive states. Psychol Med
33(2):351356
Paterniti S, Niedhammer I, Lang T, Consoli SM (2002) Psychosocial
factors at work, personality traits and depressive symptoms:
longitudinal results from the GAZEL Study. Br J Psychiatry
181(2):111117
Plaisier I, de Bruijn JGM, de Graaf R, Have MT, Beekman ATF,
Penninx BWJH (2007) The contribution of working conditions
and social support to the onset of depressive and anxiety
disorders among male and female employees. Soc Sci Med
64(2):401410
Raghunathan TE (2004) What do we do with missing data? Some
options for analysis of incomplete data. Annu Rev Public Health
25:99117
Rugulies R, Bultmann U, Aust B, Burr H (2006) Psychosocial work
environment and incidence of severe depressive symptoms:
prospective findings from a 5-year follow-up of the Danish work
environment cohort study. Am J Epidemiol 163(10):877887
Sanne B, Torp S, Mykletun A, Dahl AA (2005) The Swedish demandcontrol-support questionnaire (DCSQ): factor structure, item
analyses, and internal consistency in a large population. Scand J
Public Health 33(3):166174
Shields M (2006) Stress and depression in the employed population.
Health Rep 17(4):1129
Sinokki M, Hinkka K, Ahola K, Koskinen S, Kivimaki M, Honkonen
T, Puukka P, Klaukka T, Lonnqvist J, Virtanen M (2009) The
association of social support at work and in private life with
mental health and antidepressant use: the health 2000 study.
J Affect Disord 115(12):3645
123
605
depression and anxiety disorders in the Danish workforce.
BMC Public Health 8:280
Ylipaavalniemi J, Kivimaki M, Elovainio M, Virtanen M, KeltikangasJarvinen L, Vahtera J (2005) Psychosocial work characteristics
and incidence of newly diagnosed depression: a prospective cohort
study of three different models. Soc Sci Med 61(1):111
123