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If the precise acid-base derangement is not immediately clear (e.g. middle column) then remember the
following points:
Always cotrsicler tlre clinical context when irrterpreting
acid-base status.
Metabolic co{-npensation takes days to occtlr, re$.Piratory
compensation takes minutes.
Overcompensation does not occur.
An apparent compensatory resPonse cor.rld represent an opposing
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(22-28 mmol/l)
pH (7.3$-7.a5)
Note that with a very mild acidaemia or alkalaemia both PaCO2 and
HCO, may be just within the "normal range" (considered to be a mild
mixed acid-base disturbance).
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Figure 22 Acid-bose
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