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Fall 2007
Calculate the molarity of your standard Benzoic Acid (PhCO2H; Molecular Weight: 122.12) solution:
= X mole PhCO2H
1000 mL water
Benzoic Acid
(PhCO2H)
M.W. = 122.12
To calculate amount of PhCO2H remaining in aqueous solution after extraction with 10 mL of methylene chloride, titrate aqueous layer with 0.02M NaOH
Calculate the amount of PhCO2H extracted into the methylene chloride layer
0.122 g PhCO2H
4.
Calculate Kd
Kd = C methylene chloride
C water
Z g PhCO2H / 10 mL
(Y g PhCO2H) / 50 mL
Z / 10
Y / 50
= Calculated Kd
-1-
CHM 2201
Organic Chemistry Lab I
Department of Chemistry
Villanova University
Fall 2007
C. Two 5 mL Extractions
1.
2.
To calculate amount of PhCO2H remaining in aqueous solution after extraction with 2 x 5 mL of methylene chloride, titrate aqueous layer with ~0.02M NaOH
Calculate the total amount of PhCO2H extracted into the 2 x 5 mL methylene chloride layers
0.122 g PhCO2H
_________________________________________________________________________________________________________________________________
4. Calculate theoretical amount of PhCO2H that should be removed by 2 x 5 mL metheylene chloride extractions using Kd calculated in Step B4. For the first
5 mL extraction with methylene chloride where W is the amount of benzoic acid extracted into methylene chloride:
Kd = C methylene chloride
C water
W g PhCO2H / 5 mL
=
(0.122 g PhCO2H - W g PhCO2H) / 50 mL
W/5
= Calculated Kd (value determined in B4)
(0.122 W) / 50
( Kd = known quantity; solve equation for W).
Repeat this calculation for the second 5 mL extraction using the W value determined above and where A is the amount of benzoic acid extracted into the second
5 mL portion of methylene chloride:
Kd = C methylene chloride
C water
A g PhCO2H / 5 mL
=
(0.122 g PhCO2H - W g PhCO2H A g PhCO2H) / 50 mL
A/5
= Calculated Kd (value determined in B4)
(0.122 W A) / 50
-2-