David, Melissa D.

BSN4Y1-2B
Generic

Indication

Contraindication

Action

Nrsg. Responsibilities

Miscellaneous
respiratory tract
drugs

Adjunct therapy for

abnormal viscid or
thickened mucous
secretions in patients
with pneumonia

Use cautiously in
elderly or debilitated
patients with severe
respiratory
insufficiency. Use IV
formulation cautiously
in patients with
asthma or a history of
bronchospasm

Mucolytic that reduces

the viscosity of
pulmonary secretions
by splitting disulfide
linkages between
mucoprotein molecular
complexes.

Drug is physically or chemically incompatible

with tetracyclines, erythromycin lactobionate,
amphotericin B, and ampicillin sodium. If given
by aerosol inhalation, nebulize these drugs

Omeprazole

Proton Pump
Inhibitors (PPI)

Short-term treatment
of active duodenal
ulcer; First-line
therapy in treatment
of heartburn or
symptoms of
gastroesophageal
reflux disease

Long-term use for

gastroesophageal
reflux disease,
duodenal ulcers;
lactation

Suppresses gastric
acid secretion by
inhibiting the H+, K+ATPase enzyme
system [the acid
(proton H+) pump] in
the parietal cells.

Monitor urinalysis for hematuria and

proteinuria. Periodic liver function tests with
prolonged use.

Spironolactone

Potassiumsparing diuretic

Primary
hyperaldosteronism,
adjunctive therapy in
the treatment of
edema associated
with CHF, essential
hypertension.

Acute renal
insufficiency,
progressive renal
failure, hyperkalemia,
and anuria.

Mild diuretic that acts

on the distal tubule to
inhibit sodium
exchange for
potassium, resulting in
increased secretion of
sodium and water
conservation of
potassium

Take as directed with a snack or meals to

minimize GI upset. Report if nausea, bloating,
anorexia, vomiting or diarrhea persist.

Antibiotic,

Treatment of adults

Contraindicated with

interferes with DNA by

Administer oral drug 1 hr before or 2 hr after

Acetylcysteine

Classification

Acetadote,
Mucomyst

Aldactone

Levofloxacin

Fluoroquinolone

Levaquin

Furosemide

Loop diuretic

Lasix

Meropenem

Carbapenem
antibiotic

Merrem

Diazepam

Valium

Antianxiety
agents,
anticonvulsants,
sedative/
hyptonics

Evangelista, Kevin D.

with communityacquired pneumonia,

acute maxillary
sinusitis caused by
susceptible bacteria

allergy to
fluoroquinolones,
pregnancy, and
lactation.

inhibiting DNA synase

replication in
susceptible gramnegative and grampositive bacteria,
preventing cell
reproduction

meals with a glass of water; separate oral drug

from other cation administration, including
antacids, by at least 2 hr.

Edema associated
with CHF, cirrhosis,
renal disease, Acute
pulmonary edema

Severe sodium and

water depletion,
hypokalaemia,
hyponatraemia,
precomatose states
associated with liver
cirrhosis, anuria or
renal failure.

Inhibits reabsorption of
Na and chloride
mainly in the
medullary portion of
the ascending Loop of
Henle.

Reduce dosage if given with other

antihypertensives; readjust dosage gradually
as BP responds.

Susceptible infections
including complicated
skin and skin
structure infections
(SSSI),
intraabdominal
infections, bacterial
meningitis.

Penicillin,
cephalosporin, or
other -lactam allergy

Inhibits bacterial cell

wall synthesis

For IV bolus (doses of 1 g) or infusion only. Do

not use a flexible container in series
connections.

Anxiety

Cross-sensitivity with
other
benzodiazepines,
Comatose patients

Ensure that patient is well hydrated during

course of therapy.

Administer with food or milk to prevent GI

upset.

Do not mix with or physically add to solutions

containing other drugs.

Depress the CNS,

probably by
potentiating GABA, an
inhibitory
neurotransmitter

Monitor BP, PR,RR prior to periodically

throughout therapy and frequently during IV
therapy

BSN4Y1-2B
Generic

Indication

Contraindication

Action

Nrsg. Responsibilities

Miscellaneous
respiratory tract
drugs

Adjunct therapy for

abnormal viscid or
thickened mucous
secretions in patients
with pneumonia

Use cautiously in
elderly or debilitated
patients with severe
respiratory
insufficiency. Use IV
formulation cautiously
in patients with
asthma or a history of
bronchospasm

Mucolytic that reduces

the viscosity of
pulmonary secretions
by splitting disulfide
linkages between
mucoprotein molecular
complexes.

Drug is physically or chemically incompatible

with tetracyclines, erythromycin lactobionate,
amphotericin B, and ampicillin sodium. If given
by aerosol inhalation, nebulize these drugs

Omeprazole

Proton Pump
Inhibitors (PPI)

Short-term treatment
of active duodenal
ulcer; First-line
therapy in treatment
of heartburn or
symptoms of
gastroesophageal
reflux disease

Long-term use for

gastroesophageal
reflux disease,
duodenal ulcers;
lactation

Suppresses gastric
acid secretion by
inhibiting the H+, K+ATPase enzyme
system [the acid
(proton H+) pump] in
the parietal cells.

Monitor urinalysis for hematuria and

proteinuria. Periodic liver function tests with
prolonged use.

Spironolactone

Potassiumsparing diuretic

Primary
hyperaldosteronism,
adjunctive therapy in
the treatment of
edema associated
with CHF, essential
hypertension.

Acute renal
insufficiency,
progressive renal
failure, hyperkalemia,
and anuria.

Mild diuretic that acts

on the distal tubule to
inhibit sodium
exchange for
potassium, resulting in
increased secretion of
sodium and water
conservation of
potassium

Take as directed with a snack or meals to

minimize GI upset. Report if nausea, bloating,
anorexia, vomiting or diarrhea persist.

Antibiotic,
Fluoroquinolone

Treatment of adults
with communityacquired pneumonia,

Contraindicated with
allergy to
fluoroquinolones,

interferes with DNA by

inhibiting DNA synase
replication in

Administer oral drug 1 hr before or 2 hr after

meals with a glass of water; separate oral drug
from other cation administration, including

Acetylcysteine

Classification

Acetadote,
Mucomyst

Aldactone

Levofloxacin

Levaquin

Furosemide

Loop diuretic

Lasix

Meropenem

Carbapenem
antibiotic

Merrem

Diazepam

Valium

Antianxiety
agents,
anticonvulsants,
sedative/
hyptonics

acute maxillary
sinusitis caused by
susceptible bacteria

pregnancy, and
lactation.

susceptible gramnegative and grampositive bacteria,

preventing cell
reproduction

antacids, by at least 2 hr.

Edema associated
with CHF, cirrhosis,
renal disease, Acute
pulmonary edema

Severe sodium and

water depletion,
hypokalaemia,
hyponatraemia,
precomatose states
associated with liver
cirrhosis, anuria or
renal failure.

Inhibits reabsorption of
Na and chloride
mainly in the
medullary portion of
the ascending Loop of
Henle.

Reduce dosage if given with other

antihypertensives; readjust dosage gradually
as BP responds.

Susceptible infections
including complicated
skin and skin
structure infections
(SSSI),
intraabdominal
infections, bacterial
meningitis.

Penicillin,
cephalosporin, or
other -lactam allergy

Inhibits bacterial cell

wall synthesis

For IV bolus (doses of 1 g) or infusion only. Do

not use a flexible container in series
connections.

Anxiety

Cross-sensitivity with
other
benzodiazepines,
Comatose patients

Ensure that patient is well hydrated during

course of therapy.

Administer with food or milk to prevent GI

upset.

Do not mix with or physically add to solutions

containing other drugs.

Depress the CNS,

probably by
potentiating GABA, an
inhibitory
neurotransmitter

Monitor BP, PR,RR prior to periodically

throughout therapy and frequently during IV
therapy