Professional Documents
Culture Documents
TB by the numbers
One third of the worlds population is infected
with M. tuberculosis
5-10% will develop active disease
Almost 2 million persons die annually almost
5,000 every day
It is estimated that each case left untreated
can infect an average of 10 15 persons
annually before death
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All forms of TB
8.8 million
(8.59.2 million)
HIV-associated TB
Multidrugresistant TB
Estimated number of
deaths, 2010
1.1 million*
(0.91.2 million)
1.1 million
350,000
(1.01.2 million)
(320,000390,000)
~ 650,000
out of 12 million (11-14 million)
prevalent TB cases
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No one is spared
John Keats
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George Orwell
3,000
Cases
10
2,000
1,500
Rate
1,000
500
0
1980
1983
1986
1989
1992
1995
1998
2001
2004
2007
Number of Cases
2,500
Pathogenesis of Tuberculosis
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14
Biology of M. tuberculosis
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3.32 X 10-9
Isoniazid:
2.56 X 10-8
Ethambutol:
1.0 X 10-7
[Streptomycin:
2.29 X 10-8]
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Treatment of Tuberculosis
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23
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29
Amikacin
1.0
Capreomycin
2.5
Ethionamide
5.0
Kanamycin
2.5
Linezolid
1.0
Moxifloxacin
0.25
2.0
PAS
4.0
Rifabutin
0.5
Streptomycin
1.0
0-<3
3-<6
6-<12
12-<18
>18
No data available
Subnational data only
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning
the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border
lines for which there may not yet be full agreement.
WHO 2011. All rights reserved
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0-<6
6-<12
12-<30
30-<50
>50
No data available
Subnational data only
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning
the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border
lines for which there may not yet be full agreement.
WHO 2011. All rights reserved
www.oahpp.ca
OntarioOntario
XDR-TB
Argentina
Burkina Faso
Armenia
Bhutan
Australia
Cambodia
Austria
Canada
Azerbaijan Chile
Bangladesh China
Belarus
Colombia
Belgium
Czech Republic
Benin
Dominican Republic
Botswanawww.oahpp.ca
Ecuador
Brazil
Egypt
Estonia
Japan
France
Kazakhstan
Georgia
Kenya
Germany
Kyrgyzstan
Greece
Latvia
India
Lesotho
Indonesia
Lithuania
Iran (Islamic Rep. of) Mexico
Ireland
Mongolia
Israel
Mozambique
Italy
Myanmar
Namibia
Nepal
Netherlands
Niger
Norway
Pakistan
Peru
Philippines
Poland
Portugal
Qatar
Republic of Korea
Republic of Moldova
Romania
Russian Federation
Slovenia
South Africa
Spain
Swaziland
Sweden
Tajikistan
Thailand
WHO 2011
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37
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Thank-you!
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