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F. S.
Age
35 y.o
Height
53
Diagnosis
Sex
Female
Weight
60 kg
Website
milkv.co.vu
A/N
youre welcome J
Author
DRUG DATA
Generic name:
Celecoxib
CLASSIFICATION
Pharmacologic:
Specific COX-2
enzyme inhibitor
Trade name/s:
Celebrex
Patients dose:
200 mg BID
Maximum dose:
400mg/day PO
Therapeutic:
Nonopioid analgesic
Pregnancy Category
Risk: D
MECHANISM OF
ACTION
Minimum dose:
50mg/day PO
Available forms:
Capsules 50,
100, 200, 400mg
Onset:
Slow, PO
Peak:
3 hrs, PO
Route:
PO
Duration:
unknown
INDICATIONS
General:
> acute & longterm treatment of
signs and
symptoms of
rheumatoid
arthritis &
osteoarthritis
> reductions of
the no. of
colorectal polyps
in FAP
> management of
acute pain
> treatment of
primary
dysmenorrhea
> relief or signs&
symptoms of
juvenile
rheumatoid
arthritis
CONTRAINDICATI
ON
Contraindicated with
allergies to
sulphonamides,
celecoxib, NSAIDs or
aspirin, significant renal
impairment;
perioperative pain post
CABG surgery;
pregnancy (third
trimester); lactation
Precaution:
Use cautiouslywith
impaired hearing,
hepatic, and CV
conditions
ADVERSE
EFFECTS
CNS: headache,
dizziness,
somnolence,
insomnia, fatigue,
tiredness, tinnitus,
ophthalmologic
effects
Dermatologic: rash,
pruritus, sweating,
dry mucous
membranes,
stomatitis
GI: nausea,
abdominal pain,
dyspepsia,
flatulence, GI
bleeding
Other:
Peripheral edema,
anaphylactoid
reactions to
anaphylactic shock
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
Before:
> check the doctors order
> wash hands before administration
>explain about the importance and
purpose of the drug to patient/SO
> assess skin color and lesions,
reflexes, sensations, edema, serum
electrolytes
Hematologic:
neutropenia,
eosinophilia,
leukopenia,
pancytopenia,
thrombocytopenia,
bone marrow
depression,
menorrhagia
Patients actual
indication:
celecoxib is
prescribed to
postpartum
mothers to relieve
and alleviate
acute pain
NURSING
RESPONSIBILITIE
S
Source: 2011
Lippincotts NDG
During:
> administer the right drug: recheck
the label
> administer drug with food or after
meals if GI upset occurs
> Establish safety measures if CNS
or visual disturbances occur
> arrange for periodic ophthalmologic
examination during long-term therapy
> take note for side effects
After:
> document and record.
> provide positioning and
environmental control to reduce pain
> provide warmth, positioning and
rest to reduce inflammation
> if overdose occurs, institute gastric
lavage, induction of emesis nd
supportive therapy
> monitor patients V/S.