Republic of the Philippines

CAVITE STATE UNIVERSITY

Don Severino Delas Alas Campus
Indang, Cavite

VISION
A premier university in historic Cavite
recognized for excellence in the
development of morally upright and globally
competitive individuals.

MISSION
Cavite State University shall provide excellent,
equitable and relevant educational
opportunities in the arts, science and
technology through quality instruction and
relevant research and development activities. It
shall produce professional, skilled and morally
upright individuals for global competitiveness.

Drug Study
Initials of Patient:
Age
Sex:

DRUG
Generic Name:
Albendazole
Brand Name:
Albenza
Classification:
Anthelmintic
Dosage:
400mg
Route:
Oral
Frequency:
OD

Form:

Date of Admission:
Diagnosis:
Date of Medication Started:

MECHANISM OF
ACTION
Albendazole is found
to inhibit the
polymerization of
the parasite tubulin
into microtubules.
There is a higher
affinity of
albendazole to the
parasite tubulin and
so the activity is
mediated mainly
against the parasite
rather than on the
host. The loss of the
cytoplasmic
microtubules leads to
impaired uptake of
glucose by the larval
and adult stages of
the parasites. The
worm is then unable

INDICATION

CONTRAINDICATIO
EFFECTS
N
Prescribed for
If you are allergic to any Central Nervous
tapeworm infections, ingredient in albendazole System- Headache,
hydatid cyst disease, or to benzimidazoles
seizures, confusion,
cysticercosis or
raised intracranial
neurocysticercosis,
pressure,
capillariasis,
dizziness/vertigo,
cutaneous larva
signs that meningeal
migrans, giardiasis,
sings.
microsporidiosis
including Septata
Skin- Reversible hair
intestinalis infection,
loss, infection,
intestinal parasites in
hypersensitivity
immigrants,
including rash and
strongyloidiasis,
hives, allergic
trichinosis,
reactions.
trichostrongyliasis. I
t works by killing
Gastrointestinalsensitive parasites.
Abdominal pain,
nausea/vomiting.
Genitourinary- Acute

NURSING
RESPONSIBILITIES
Pre-Administration:
-Follow 10 Rs of giving
medication
Intra-Administration:
-Give oral drug with full
glass of water.
-Make sure that drug is
taken.

- In young children, the

tablets should be crushed or
chewed and swallowed
with glass of water.

Tablet
Color:

to maintain energy
production, which
leads to
immobilization and
eventual death
(Dayan, 2003). A
secondary acton of
albendazole may be
the be the inhibition
of the enzyme
fumarate reductase,
which is helminthspecific
(PharmGKB).

kidney failure, dark

urine.
Liver- Abnormal
Liver Function Tests,
inflammation of liver
Blood- Decrease in
the number of white
blood cells,
thrombocytes,
hemoglobin.
MiscellaneousFever.

DRUG
Generic Name:
Diphenhyramine
Hydrochloride
Brand Name:
Benadryl
Classification:
Antihistamine
Dosage:
50mg
Route:
Oral
Frequency:
T.I.D
Form:
Tablet
Color:

MECHANISM OF
ACTION
Histamine is
released by the body
during several types
of allergic reactions
and--to a lesser
extent--during some
viral infections, such
as the common cold.
When histamine
binds to receptors on
cells, it stimulates
changes within the
cells that lead to the
release of chemicals
that cause sneezing,
itching, and
increased mucus
production.
Antihistamines
compete with
histamine for cell
receptors and bind to
the receptors without
stimulating the cells.

INDICATION

CONTRAINDICATION

EFFECTS

It is used for the

symptomatic relief
of
allergic conditions
including urticaria
and angioedema.
Diphenhydramine is
used for its
abtimiscarinic
properties in the
control of
parkinsonism and
drug-induced
extrapyramidal
disorders

Hypersensitivity
to
diphenhydramine
hydrochloride and other
antihistamines of similar
chemical structure.

General: Urticaria,
drug rash,
anaphylactic shock,
photosensitivity,
excessive
perspiration, chills,
dryness of mouth,
nose, and throat.
Cardiovascular
System:
Hypotension,
headache,
palpitations,
tachycardia,
extrasystoles.
Hematologic
System: Hemolytic
anemia,
thrombocytopenia,
agranulocytosis.
Nervous System:
Sedation,
sleepiness,
dizziness, disturbed
coordination,
fatigue, confusion,

NURSING
RESPONSIBILITIES
Assessment
History: Allergy to any
antihistamines, narrowangle glaucoma, stenosing
peptic ulcer, symptomatic
prostatic hypertrophy,
asthmatic attack, bladder
neck obstruction,
pyloroduodenal
obstruction, third trimester
of pregnancy, lactation
Physical: Skin color,
lesions, texture; orientation,
reflexes, affect; vision
examination; P, BP; R,
adventitious sounds; bowel
sounds; prostate palpation;
CBC with differential
Interventions
> Administer with food if
GI upset occurs.
> Administer syrup form if
patient is unable to take
tablets.
> Monitor patient response,

restlessness,
and arrange for adjustment
excitation,
of dosage to lowest
nervousness,
possible effective dose.
tremor, irritability,
insomnia, euphoria,
paresthesia, blurred
vision, diplopia,
vertigo, tinnitus,
acute labyrinthitis,
neuritis,
convulsions.
GI System:
Epigastric distress,
anorexia, nausea,
vomiting, diarrhea,
constipation.
GU System:
Urinary frequency,
difficult urination,
urinary retention,
early menses.
Respiratory
System: Thickening
of bronchial
secretions, tightness
of chest or throat
and wheezing,
nasal stuffiness.

NAME OF THE
DRUG

MECHANISM OF
ACTION

INDICATION

CONTRAINDICA
TION

EFFECTS

NURSING
RESPONSIBILITIES

Brand Name:
Tempra
Generic Name:
Paracetamol
Classification:
Non-narcotic analgesics
and antipyretics
Route:
P.O.
Frequency:
q4h-q6h
Dosage:
500 mg

Unknown. Thought
Relief of mild pain
to produce analgesia
or fever
by blocking
generation of pain
impulses, probably
by inhibiting
prostaglandin
synthesis in the CNS
or the synthesis or
action of other
substances that
sensitize pain
receptors to
mechanical or
chemical stimulation.
It is thought to relieve
fever by central
action in the
hypothalamic heatregulating center.

Contraindicated
in patients with
hypersensitivity
to the drug

Hematologic:
If there is fever,
hemolyticanemia,
assess patients fever
neutropenia,
or pain: type of pain,
leukopenia,
location, intensity,
pancytopenia
duration, temperature,
Hepatic: liver damage,
and diaphoresis.
Tell patient not to use
jaundice
Metabolic:hypoglycem
for marked fever
ia
(higher than 39.5
Skin: rash, urticaria
C). Fever persisting
longer than 3 days, or
recurrent fever unless
directed by
prescriber.
Avoid giving patient
aspirin or aspirin-like
analgesics because it
inhibits platelet
aggregation.
Teach client warning
signs that needs
immediate attention
of the physician.
Evaluate therapeutic
effects.