PersonalCare

Product Name INCI Names Ingredients % CAS Number Spectrum Maximum Use Level Approvals pH Availability Incompatibility Uses
Traditional Cosmetic Preservatives
Glycacil S






Iodopropynyl
Butylcarbamate
(IPBC)




IPBC, sodium
bicarbonate





10
90





55406-53-6
144-55-8





Yeast &
mold





EU: 0.2 % in rinse-of; 0.1 %
in leave-on, except in creams
& lotions; 0.075 %
in antiperspirants /
deoderants;
Japan: 0.2 %;
USA: 1.0 %
EU: Not allowed for oral
hygiene and lip products;
Not allowed in preparations
for children under the age of
3 except in bath products,
shower gels and shampoos.
Japan / USA: Cannot be used
in aerosol products
210






Commercial






Can be inactivated
by strong reducing
agents, acids, and
bases.



Personal care products:
shampoos, gels, bodywash,
cream, lotion




Glycacil L


Iodopropynyl
Butylcarbamate
(IPBC)
IPBC, PEG-4 Laurates


10
90

55406-53-6



Yeast &
mold

Same as Glycacil S


Same as Glycacil S


210


Commercial


Can be inactivated
by strong reducing
agents, acids, and
bases.
Personal care products:
shampoos, gels, bodywash,
cream, lotion
Glycacil 2000




Iodopropynyl
Butylcarbamate
(IPBC)


IPBC,
Cyclodextrin-derived
encapsulating agent,
water

6
47
47


55406-53-6
7732-18-5



Yeast &
mold



EU: 0.33 % in rinse-of;
0.16 % in leave-on, except in
creams & lotions; 0.125 % in
antiperspirants /deoderants;
Japan: 0.33 %;
USA: 1.6 %
Same as Glycacil S




210




Commercial




Can be inactivated
by strong reducing
agents, acids, and
bases.

Personal care products:
shampoos, gels, bodywash,
cream, lotion


Glydant XL-1000

DMDM Hydantoin

DMDM Hydantoin

100

6440-58-0

Bacteria

EU: 0.6 %

EU: Listed in Annex VI.
Finished products containing
DMDMH must be labeled
with the warning contains
formaldehyde if the
concentration >0.05 %.
210

Commercial



Personal care products:
shampoos, gels, bodywash,
cream, lotion
Japan: Listed on the positive list. However, the following warning must be labeled:
should not be used by infants or by people who are hypersensitve to formaldehyde.
Can be used at a level up to 0.3 % only in products that are rinsed after use.
USA: Approved by CTFA for both rinse-of and leave-on applications.
Glydant 2000





DMDM Hydantoin





DMDM Hydantoin





55





6440-58-0





Bacteria





Same limits for DMDMH as
Glydant XL-1000




Approvals for DMDMH





210





Commercial











Personal care products:
shampoos, gels,
bodywash, cream, lotion
Lonzas patented low free
formaldehyde product
(<0.1 %)
Glydant

DMDM Hydantoin

DMDM Hydantoin

55

6440-58-0

Bacteria

Same limits for DMDMH as
Glydant XL-1000
Approvals for DMDMH

210

Commercial



Personal care products:
shampoos, gels, bodywash,
cream, lotion
Glydant Plus


DMDM Hydantoin,
Iodopropynyl
Butylcarbamate
(IPBC)
DMDM Hydantoin,
IPBC

100


6440-58-0,
55406-53-6

Broad


Limits for DMDMH and IPBC


Approvals for DMDMH
and IPBC

210


Commercial





Personal care products:
shampoos, gels, bodywash,
cream, lotion
Glydant Plus
Liquid
DMDM Hydantoin,
Iodopropynyl
Butylcarbamate
(IPBC)
DMDM Hydantoin,
IPBC, Butylene
Glycol, Water
50 6440-58-0,
55406-53-6
Broad Limits for DMDMH and IPBC Approvals for DMDMH
and IPBC
210 Commercial Personal care products:
shampoos, gels, bodywash,
cream, lotion
Advanced Cosmetic Preservatives
Geogard 111 A


Dehydroacetic Acid


Dehydroacetic Acid


100


520-45-6


Yeast &
mold

EU: 0.6 %
Japan: 0.5 %,
USA: CIR 0.6 %
ECOCERT permitted;
NATRUE and Soil Association
approved;
Not allowed in aerosols
27


Commercial


Efcacy is optimal
below pH 7

Personal care products:
shampoos, gels, bodywash,
cream, lotion
Geogard 111 S


Sodium
Dehydroacetate

Sodium
Dehydroacetate

100


4418-26-2


Yeast &
mold

EU: 0.68 %
Japan: 0.5 %,
USA: CIR 0.6 %
ECOCERT permitted;
NATRUE and Soil Association
approved;
Not allowed in aerosols
27


Commercial


Efcacy is optimal
below pH 7

Personal care products:
shampoos, gels, bodywash,
cream, lotion
Geogard 221


Dehydroacetic Acid,
Benzyl Alcohol, Water

Dehydroacetic Acid,
Benzyl Alcohol,
Water
8
87
5
520-45-6
100-51-6
7732-18-5
Broad


EU: 1.15 %
Japan: 0.2 % eye area limit
USA: CIR 5.75 %
ECOCERT permitted;
NATRUE and Soil Association
approved;
Not allowed in aerosols
27


Commercial


Efcacy is optimal
below pH 7

Personal care products:
shampoos, gels, bodywash,
cream, lotion
Geogard Ultra Gluconolactone,
Sodium Benzoate
Gluconolactone,
Sodium Benzoate,
Calcium Gluconate
74
25
1
90-80-2
532-32-1
299-28-5
Broad EU: 2.5 % total max. level
of NaBenzoate
Japan: 1.0 % total max. level
of NaBenzoate
USA: Safe
ECOCERT accepted:
NATRUE and Soil Association
approved;
Japan: Not allowed for eye
mucosa membrane.
36 Commercial Efcacy is optimal
below pH 7
Personal care products:
shampoos, gels, bodywash,
cream, lotion
Antimicrobial Agents
Lonzagard





Benzethonium
Chloride




Benzethonium
Chloride




100





121-54-0





Bacteria,
mild
fungicide



EU: 0.1 %
Japan: 0.5 % in rinse-of,
0.2 % in leave-on
USA: 0.55 % skin, 0.2 %
eye area

Complies with US and
European Pharmacopeia
specifcations.
EU: Not BPD supported.
Japan: Not permitted in
products with mucous
membrane contact
69





Commercial





Inactivated by
anionics, polysorbates
and lecithin.



Personal care products:
shampoos, gels, bodywash,
cream, lotion



Lonzabac PC

Polyaminopropyl
Biguanide
Polyaminopropyl
Biguanide
20

27083-27-8

Bacteria

EU: 1.5 %
Japan: 0.5 %
USA: CTFA approved
Broad approvals

57

Commercial

Inactivated by alkaline
environment.
Personal care products:
shampoos, gels, bodywash,
cream, lotion
Spectradyne Chlorhexidine
Digluconate
Chlorhexidine
Digluconate
20 18472-51-0 Bacteria EU: 1.5 %
Japan: no limit in rinse-of,
0.25 % in leave-on
USA: CIR 1.0 %
Complies with European
Pharmacopeia
specifcations
68 Commercial Unstable at elevated
temperature,
incompatible with
anionics.
Personal care products:
shampoos, gels, bodywash,
cream, lotion
Preservatives for Cosmetic Applications
www.lonza.com
www.lonza.com/personalcare
The information contained herein is believed to be correct and corresponds to the latest state
of scientifc and technical knowledge. However, no warranty is made, either expressed or
implied, regarding its accuracy or the results to be obtained from the use of such informa-
tion. Some products may not be available in all markets or for every type of application. Any
user must make his own determination and satisfy himself that the products supplied by
Lonza Group Ltd and the information and recommendations given by Lonza Group Ltd are
(i) suitable for intended process or purpose, (ii) in compliance with environmental, health
and safety regulations, and (iii) will not infringe any third partys intellectual property rights.

2011 Lonza Ltd
Product Name Ingredients % EPA Registration Spectrum pH Availability Incompatibility EPA Registered Uses
Glycacil SG

Iodopropynyl Butylcarbamate (IPBC) /
Inert ingredients
6.0
94.0
5383-91-6836

Yeast & mold

210

Commercial

Can be inactivated by strong
reducing agents, acids, and
bases.
Wood, sapstain control, millwork, household cleaning products,
detergents and soft soaps, metalworking fuids, room
deoderizers and air fresheners, paper coatings
Dantogard

1,3-Bis (hydroxymethyl)-5,5-dimethyl hydantoin /
Hydroxymethyl-5,5-dimethyl hydantoin /
Inert Ingredients
32.0
7.5
60.5
6836-119

Bacteria

210

Commercial



Liquid detergents, soft soaps, paints, room deoderizers, air
fresheners, surfactants, polymer emulsions, coatings, textiles,
inks, adhesives, latex
Dantogard 2000

1,3-Bis (hydroxymethyl)-5,5-dimethyl hydantoin /
Hydroxymethyl-5,5-dimethyl hydantoin /
Other Ingredients
33.2
31.5
35.3
6836-322

Bacteria

210

Commercial



Liquid detergents, soft soaps, paints, room deoderizers, air
fresheners, surfactants, polymer emulsions, coatings, textiles,
inks, adhesives, latex
Dantogard XL-1000

DMDM Hydantoin

99.5

6836-199

Bacteria

210

Commercial



Liquid detergents, soft soaps, paints, room deoderizers, air
fresheners, surfactants, polymer emulsions, coatings, textiles,
inks, adhesives, latex
Dantogard Plus Liquid


1,3-Bis(hydroxymethyl)-5,5-dimethyl hydantoin /
1-(hydroxymethyl)-5,5- dimethylhydantoin /
3-lodo-2-propynyl butyl carbamate /
Inert Ingredients
26.9
25.5
2.5
45.1
6836-271


Broad


210


Commercial





Fabric softeners, household cleaning products, latex
for paper coatings, liquid detergents and soaps, metal-working
fuids
Dantogard Plus


1,3-Bis(hydroxymethyl)-5,5-dimethyl hydantoin /
Hydroxymethyl-5,5-dimethyl hydantoin /
3-lodo-2-propynyl butyl carbamate /
Inert ingredients
87.0
0.4
4.5
8.1
6836-200


Broad


210


Commercial





Fabric softeners, household cleaning products, latex
for paper coatings, liquid detergents and soaps, metal-working
fuids
Lonza Mildew
Preservative
Didecyl dimethyl ammonium chloride (aq) 50.0 6836-030 Bacteria 711 Limited Inactivated by anionics Laundry sanitizer
Dantoserve SG


1,3-Bis (hydroxymethyl)-5,5-dimethyl hydantoin /
Hydroxymethyl-5,5-dimethylhydantoin /
1,2-benzoisothiazolinon-3-one /
Other Ingredients
33.2
31.5
1.1
35.3
6836-306


Broad


210


Commercial





Detergent products, sealants, caulks, latex, surfactant
solutions, tackifers, paints, stains, coatings, adhesives,
metalworking fuids, inks, polishes, waxes, carpet
shampoos, room deoderizers
Dantoserve MS


1,3-bis(hydroxymethyl)-5,5 dimethyl hydantoin /
1-(hydroxymethyl)-5,5-dimethylhydantoin /
1,2-benzoisothiazolinon-3-one /
Other Ingredients
29.4
27.9
1.1
41.6
6836-307


Broad


210


Commercial





Mineral slurries (clay, kaolin clay, calcium carbonate, titanium
dioxide)

Hyamine 1622 50 %

Diisobutylphenoxyethoxy Ethyl Dimethyl Benzyl
Ammonium Chloride Monohydrate /
Other ingredients
49.4

50.6
6836-93

Bacteria

711

Commercial

Inactivated by anionics

For manufacturing into end-use formulation
preservatives only
Hyamine 1622 Crystals

Diisobutylphenoxyethoxy Ethyl Dimethyl Benzyl
Ammonium Chloride Monohydrate /
Other ingredients
98.8

1.2
6836-91

Bacteria

711

Commercial

Inactivated by anionics

For manufacturing into end-use formulation
preservatives only
Carboserve

Didecyl dimethyl ammonium bicarbonate and
Didecyl dimethyl ammonium carbonate /
Other ingredients
50.0

50.0
6836-323

Broad

711

Commercial

Inactivated by anionics

For use in oil feld waterfood systems, metalworking fuids,
industrial and consumer products; household cleaning
products and wipes for use on hard, non-porous surfaces
Lonzabac 12 Bis (3-aminopropyl) dodecylamine /
Inert ingredients
91.4
8.6
6836-329 Broad 711 Commercial Incompatible with aldehydes Metalworking fuids and oil felds
EPA Registered Preservatives
Lonza Inc.
90 Boroline Road
Allendale, NJ 07401
Tel +1 201 316 9200
Fax +1 201 785 9989
contact.allendale@lonza.com