PharmacyPrep.

com Asthma
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26
PHARMACY PREP

ASTHMA
Asthma In Infants & Children

1-A 4-year child was newly diagnosed with asthma, all of the following questions are
important to ask his mother EXCEPT:
A. How many days he missed school
B. Severity of symptoms
C. How often symptoms come
D. Can your child inhale powder dose inhalers
E. Does he wake up in night due to asthma symptoms
Ans-D
Tips: Keep one MDI at school and other at home

2-What is the best dosage form for inhalation drugs, in children age <5 year age?
A-MDI +aerochamber+face mask
B-Turbuhaler
C-Diskus
D-handihaler
E-Nebulizer
Ans-A

3. Recommend use of spacer in inhaler, because
I. Enhance the medication to reach lungs
II. Avoid deposition of medication in mouth
III. Reduce oral thrush infections
A. I only
B. III only
C. I and II
D. II and III
E. All of the above
Answer: E
Tips: spacer enhances the medication to reach lungs, reduce deposition of medication in
mouth.

4- Patient 65 years old with asthma, using salbutamol inhaler 2 puffs PRN, Fluticasone
inh, B.I.D., and Zafirlukast 20mg twice daily. He developed sore throat, and his Dr.
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prescribed Erythromycin cap 500mg QID for him. The pharmacist noticed in his
computer that there is a drug-drug interaction between Zafirlukast and Erythromycin.
This interaction of Erythromycin will:
I. Result in decreased plasma level of Zafirlukast bioavailability
II. Result in an increase in plasma level of Zafirlukast bioavailability
III. It is not of clinical significant
A-I only
B-III only
C-I and II only
D-II and III only
E-All of the above
Ans: A
Ref: CPS 2007 Page 8

5 About Montelukast, all true, except:
A. Take with or after food
B. For asthma control before physical exercises
C. Take daily at bedtime (QHS)
D. For kids 2 or more year older
E. It has steroid sparing effect
Ans-B

6. A 65 year old patient with asthma and is susceptible to tremor and tachycardia when
he uses B2-agonists like salbutamol inhaler. Best initial therapy for him:
(A) Cromoglycate Na
(B) Zafirlukast
(C) Ipratropium inh
(D) Tiotropium inh
(E) Corticosteroid inh
Answer: (C)
Reference: Therapeutic Choices 5th edition Page 628

7. The following(s) is/are true with respect to Omalizumab:
I A new monoclonal Ab
II Indicated for patients with moderate to severe asthma
III Used for those patients who have inadequately controlled inhaled corticosteroids
(A) I only
(B) III only
(C) I and II
(D) II and III
(E) All of the above
Answer: (E)

8. A 30 years old female patient taking steroids puffers since 7 years ago. She has a
family history of diabetes. He is experiencing Polydipsia and yeast infection with
Polyuria. You advise him to see the physician because you doubt that he might be
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diabetic, all are consistent with your conclusion EXCEPT:
(A) The long term use of the steroid puffers
(B) Family history
(C) Signs and symptoms
(D) Thrush in his mouth
(E) Yeast infection
Answer: (D)
TIPS: Thrash is not a marker for diabetes

9. Auxiliary labels to be put on Corticosteroid inhalers:
I Dont exceed the dose
II Rinse your mouth after use
III Dont shake the inhaler
(A) I only
(B) III only
(C) I and II
(D) II and III
(E) All of the above
Answer: (C)