(stamp of the academic unit)

PROGRAMME AND RULES OF TEACHING FOR THE COURSE/MODULE

for the academic year of 2014-2015
(syllabus)

(1) Field of
study
Medicine
(2) Level Uniform Master Degree (3) Form Stationary
(4) Profile Practical
(5) Year of
studies
5
(6) Teaching
cycle
Academic Year

(7) Course title Clinical Immunology
(9a) Course code
(8) Course
status
Obligatory
(9b) ECTS points
2.0
(10) Hours
0 30 0 0 0 30
lectures seminars
practical
classes
practical
training
laboratory
classes
SUM

(11) Academic unit
(name and detailed
address, telephone)
Department of Clinical Immunology and Transplantology
Chair of Immunology
Medical University of Gdask
Dbinki 7 str., building 27 II floor 80-952 Gdask
tel. (58) 3491593, (58) 3491590 fax (58) 349 1591
e-mail: immuno@gumed.edu.pl

(12A) Name and surname of the didactic director
Piotr Trzonkowski MD, PhD
Professor of Immunology
Department of Clinical Immunology and Transplantology
Chair of Immunology
Medical University of Gdask Dbinki 7 str., building 27 II floor 80-952 Gdask tel. (58) 3491593,
(58) 3491590 fax (58) 349 1591 e-mail: ptrzon@gumed.edu.pl
(12B) Names and surnames of lecturers
Prof. Piotr Trzonkowski, MD,PhD
Micha Pikua, MSc, PhD
Anna Wardowska, MSc, PhD
Grayna Moszkowska, MSc, PhD
Marcelina Grabowska, MSc
Adam Krzystyniak, MSc
Paulina Langa, MSc
Maciej Zieliski, MSc
Hanna Zieliska, MSc
Julia Kulczycka, MD,PhD
Anna Dukat-Mazurek, MSc
(13) Forms of classes, execution formula, and the allocated number of hours
Seminar
Seminars in Academic unit:
seminar room, Department of Clinical Immunology and Transplantology, MUG
(14) Language of instruction EN
(15) Teaching methods
Seminar
Multimedia presentations with
discussion.
(16) Form and manner of obtaining credit, and the key
assessment criteria or examination requirements
A. Manner of obtaining credit
Credit with grade.
B. Forms of credit
Multiple choice test (50 questions). Additional term: multiple
choice test (50 questions). Students are required to attend all
classes in order to be allowed to go for the final test. Marks
scale according to the general studies regulations, minimum
of 60% of correct answers on multiple choice test in order to
pass.
C. Key criteria
The attendance in all seminars is mandatory in order to be
allowed to make the final test. Students with absences cannot
make the final test and do not receive the credit. Those absent
should attend missed seminars with other groups.
Students are required to get 60% of correct answers on
multiple choice test in order to pass. Detailed grade scale will
match general studies regulations. The questions will include
below-described knowledge (p19).
(17) Identification of the introductory courses and the preliminary requirements
A. Formal requirements Basic immunology
B. Preliminary requirements Student should be able to give basic facts: - on the macro- and
microscopic structure of the human body, with special attention to the lymphatic system, - on the
symptoms and signs diagnosed during physical examination, elucidated with laboratory and
imaging examinations.
(18) Course objectives
The subject is intended to show the students immune background of medical conditions and the
The subject is intended to show the students immune background of medical conditions and the
ways immunology helps to diagnose and treat these diseases. Seminars cover the description of
pathogenesis and symptoms of the diseases with immune background, immune assays
performed routinely in the diagnostic process and therapeutic immune approaches applied in
order to treat diseases.
(19) Syllabus content
Seminar
The subject is intended to show the students immune background of medical conditions and the
ways immunology helps to diagnose and treat these diseases. The main topics of the seminars
include the following:
Immunity and Infection
Humoral diagnostics
Cellular diagnostics
Primary Immunodeficiencies
Secondary Immunodeficiencies
Tolerance and systemic autoimmune diseases
Organ-specific inflammatory diseases
Hypersensitivity
Transplantation
Immunotherapy

Student will obtain knowledge of the below mentioned area:
1. Genetical background of blood groups and serological conflict
2. Influence of biotic and abiotic factors on the human body
3. The process of the development of the immune system
4. Types of hypersensitivity
5. Types of immune deficiencies
6. Immune response to tumors
7. Definition of shock with special attention to septic shock
8. Genetic background of donor:recipient matching and transplant donation
9. Medicines influencing immune system: immunosuppressants, immunomodulators, sera
and vaccines
10. New trends in the development of therapy with special attention to cellular therapies and
gene therapies
11. The genetic environmental and epidemiological background of the most frequent immune
mediated diseases in children:
a)asthma, hay fever, urticarial, anaphylactic shock
b)anaemia, thrombocytopenia
c)inflammatory bowel disease, immune mediated pancreas and liver diseases
d)glomerulonephritis
e)immunoendocrinopathies
f)rheumatoid diseases
12.The genetic environmental and epidemiological background of the most frequent immune
mediated diseases in adults:
a)systemic and organ-specific autoimmune syndromes
b)rheumatoid syndromes
c)anaemia, thrombocytopenia
d)allergies
13.The immune background of the most common immune-mediated diseases of the nervous
system:
a)multiple sclerosis
b)myasthenia gravis
14.Etiology, diagnosis and prevention of the most common infectious diseases (bacterial, viral,
fungal) with special attention to pneumococci, viral hepatitis, AIDS and nosocomial infections.
15.The work of the laboratory of clinical immunology.
(20) List of literature
A. Literature required to obtain the final credit (pass the examination):
A.1. referred to during the classes
Basic and Clinical Immunology" Mark Peakman. Churchill Livingstone 2009
"Clinical Immunology" by Rich Elservier 2008
Didactic materials in GUMed extranet
A.2. used independently by the student
Basic and Clinical Immunology" Mark Peakman. Churchill Livingstone 2009
"Clinical Immunology" by Rich Elservier 2008
Didactic materials in GUMed extranet
B. Supplementary literature
Immunobiology" Janeway Ch. et al. - from 5th to 7th edition
Journal of Immunology", "Immunity", "Current Opinion in Immunology", Clinical Immunology",
"American Journal of Transplantation", "Transplant Immunology" - chosen articles shown during
seminars (available via GUMed library)
(21) Learning
effects
Awareness of the
immune
background of
human diseases
and the ways the
diseases are
diagnosed and
treated.
(22) Knowledge
Student has the knowledge of the immune, genetic and environmental
background of the most common immune-mediated diseases.
Student describes the major histocompatybility complex, knows the
oversensitive reaction types, the immune deficiency types, and the basics of
immomodulation. Student knows the genetic foundations of the donor-
recipient selection, and the basics of transplantational immunology. Student
knows the genetic determinants of the human blood group and the Rh
serological conflict. student also knows the theoretical foundations and
practical basis of the laboratory diagnostics. Student understand the
influence of biotic and abiotic factors on the human body.
(23) Skills
Student should be able to properly apply diagnostic and research methods in
the evaluation of diseases with immune background, properly interpret basic
symptoms in physical examination and results of laboratory tests, performing
differential diagnosis, presentation and critical evaluation of the results,
offering of the therapy.
Student plans the diagnostic, therapeutic, and preventive procedure.
Interprets laboratory tests and identifies the causes of the deviations. Decide
about the need to perform molecular tests.
(24) Social competencies (rudiments)
Student gains the ability of autonomous and independent performing of
particular tasks,communication skills, critical assessment of the scientific
facts and discussion, open mind for new theories.
Student is aware of his/her own limitation and possesses the skill to
continuous furtherance of his/her education. Can cooperate with
representatives of other professions in the health care area. Student has the
habit and skill to continuous furthering his/her educations.
(25) Contact
Piotr Trzonkowski MD, PhD
Professor of Immunology
Department of Clinical Immunology and Transplantology,
Chair of Immunology
Medical University of Gdask
Dbinki 7 str., building 27 II floor 80-952 Gdask
tel. (58) 3491593, (58) 3491590
fax (58) 349 1591
e-mail: ptrzon@gumed.edu.pl
Micha Pikua, MSc, PhD
Department of Clinical Immunology and Transplantology
tel. (58) 3491592, (58) 3491590
fax (58) 349 15 91
e-mail: pikula@gumed.edu.pl



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(stamp and signature of the Unit Head)

Syl l abus zatwi erdzony dni a 2014-09-07 przez: prof. dr hab. Mari a Al i cj a Dbska-l i zi e