This document provides demographic and health history information for a 49-year-old female patient admitted with right lower quadrant pain and a diagnosis of metastatic ovarian cancer. It details her chief complaint, history of present illness over the past year, past medical history, family history, and physical assessment findings on admission. It also includes an anatomy and physiology section summarizing the key structures of the female reproductive system including the external genitalia, internal organs like the vagina and uterus, and their functions.
Original Description:
4NUR-8.1 Case 4 - Gynecologic Nursing (Written Report)
This document provides demographic and health history information for a 49-year-old female patient admitted with right lower quadrant pain and a diagnosis of metastatic ovarian cancer. It details her chief complaint, history of present illness over the past year, past medical history, family history, and physical assessment findings on admission. It also includes an anatomy and physiology section summarizing the key structures of the female reproductive system including the external genitalia, internal organs like the vagina and uterus, and their functions.
This document provides demographic and health history information for a 49-year-old female patient admitted with right lower quadrant pain and a diagnosis of metastatic ovarian cancer. It details her chief complaint, history of present illness over the past year, past medical history, family history, and physical assessment findings on admission. It also includes an anatomy and physiology section summarizing the key structures of the female reproductive system including the external genitalia, internal organs like the vagina and uterus, and their functions.
Submitted by: IV-8 RLE 1 Pascual, Kimberly Mae M. Paterno, Marielle Ina S. Paulino, Katrina Sarah Mae P. Paulino, Lianne Alyzza A. Payuran, Joanna Lissa F. Pazcoguin, John Micko A.
Pelonio, Jeannie Lou N. Perez, Mark Lester M. Pesigan, Kristoffer Louis P. Pineda, Angelica Marie B. Pitargue, Maria Inna B. Pieda, Maria Angela Kristine S.
I. DEMOGRAPHIC DATA Name: M.A Age: 49 y/o Gender: Female
II. HEALTH HISTORY Chief Complaint: RLQ pain Diagnosis: Metastatic Ovarian Cancer
History of Present Illness: 1 yr PTA Noted progressive weight loss Irregularities in menstruation Dysmenorrhea on the first 2 days of menses Dysparunea 8 months PTA Noted progressive weight loss Irregularities in menstruation Dysmenorrhea Dysparunea
(-) result in pregnancy test 5 months PTA Still with progressive abdominal enlargement Weight loss and anorexia Early satiety and bloatedness Epigastric pain, nausea and vomiting 3 months PTA Still with amenorrhea Palpable node in the LUQ of her breast
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Consulted an internist -> advised mammography and breast nodule biopsy 1 month PTA Pain on the RLQ Progressive abdominal enlargement Weight loss Occasional febrile episode Dyspnea
Prompted consult and subsequent admission
Past Medical History: Hypertensive (8 yrs) maintained on Amlodipine 10 mg BID Diabetic (2 yrs) on Metformin 500mg/tab TID
Family History: (+) Family hx of colon cancer - uncle
Personal and Social History: G3 P2 (1-1-1-2) 1 st sexual contact: 16 y/o Previous intake of OCP (8 yrs) Smoker: 6-7 sticks (30 yrs)
III. PHYSICAL ASSESSMENT: Physical Examination on Admission: VS: BP 170/90, PR 113/min, RR 26, T 38.9, BMI 15 Conscious, coherent but restless Pale palpebral conjunctiva, anicteric sclera (+) nasal flaring with intercostal retraction Lagging on the L hemi-diaphragm Decrease tactile fremiti on the L Decrease BS on the L (+) 2x 1.3 mm nodular fixed mass on the L breast AC 68 cmm Bulging flanks with (+) fluid wave (+) 4x 3.8 cm palpable mass on the RLQ area with direct and rebound tenderness (+) grade 2 bipedal edema NE is essentially normal
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IV. ANATOMY AND PHYSIOLOGY: Female Reproductive System The female reproductive organ consists of the external and internal organs and the accessory organs of the breasts. EXTERNAL GENITALS - Also referred as the vulva includes the following: Mons Pubis Labia majora Labia minora Clitoris Urethral meatus and the opening of the paraurethral (skenes) glands Vaginal vestibule (vaginal orifice, vulvovaginal glands, hymen, and fossa navicularis) Perineal body The urethral meatus and the perineal body are not true parts of the female reproductive system, they are just considered because of their proximity and relationship to the vulva MONS PUBIS Also known as Mons Veneris. It is a softly rounded mound of subcutaneous fatty tissue beginning at the lowest portion of the anterior abdominal wall. The mons pubis is covered with pubic hair. The mons pubis protects the pelvic bones, especially during coitus. LABIA MAJORA The labia majora are the outer lips of the vulva, which are pads of fatty tissue that wrap around the vulva from top to bottom around the mons veneris to the perineum. It is usually covered with pubic hair, and contains numerous sweat and oil glands. LABIA MINORA The labia minora are the inner lips of the vulva, whose thin stretches of skin and tissue reside directly inside of the labia majora. The labia minora provides added protection to the vagina, urethra, and clitoris. CLITORIS The clitoris is a small light pink oval between the top of the labia minora and the clitoral hood. It is a small body of smooth spongy tissue that is highly sensitive and contains some 8,000 nerve endings and is the primary erogenous organ of women. It is protected by the prepuce, or clitoral hood, a covering of tissue similar to the labia minora. In addition, it secretes smegma, which along with other vulval secretions has a unique odor that may be sexually stimulating to the male. 4 | P a g e
URETHRAL MEATUS and PARAURETHRAL GLANDS The urethral meatus is located 1 to 2.5 cm beneath the clitoris in the midline of the vestibule; it often appears as a puckered, slitlike opening. At times the meatus is difficult to visualize because of the presence of the blind dimples, small mucosal folds, or wide variations in location. The paraurethral glands, or skenes glands, open into the porsterior wall of the urethra close to its opening. Their secretions lubricate the vaginal opening, facilitating sexual intercourse. VAGINAL VESTIBULE It is a part of the vulva between the labia minora into which the urethral opening and the vaginal opening open. The vestibule contains the vaginal opening or the introitus, which is the border between the external and internal glands. The hymen is a thin, elastic collar or semicollar of tissue that surrounds the vaginal opening. External to the hymen at the base of the vestibule are the two small papular elevations containing the openings of the ducts of the vulvovaginal (Bartholins) glands. These glands secrete a clear, thick, alkaline mucus that enhances the viability and motility of the sperm deposited in the vaginal vestibule. These gland ducts can harbor Neiserria gonorrhea and other bacteria, which can cause pus formation and abscess in the Bartholins glands. The vestibular area is innervated mainly by the perineal nerve from the sacral plexus. The area is not sensitive to touch generally; however, the hymen contains numerous free endings as receptors to pain. PERINEAL BODY The perineal body (or central tendon of perineum) is a pyramidal fibromuscular mass in the middle line of the perineum at the junction between the urogenital triangle and the anal triangle. It is found between the vagina and anus, the perineal body is essential for the integrity of the pelvic floor, particularly in females. Its rupture during delivery leads to widening of the gap between the anterior free borders of levator ani muscle of both sides, thus predisposing the woman to prolapse of the uterus, rectum, or even the urinary bladder.
INTERNAL ORGANS - The female internal reproductive organs include: Vagina Uterus Fallopian tubes and ovaries These are the target organs for estrogenic hormones and play a unique part in the reproductive cycle 5 | P a g e
VAGINA The vagina is an elastic muscular canal that extends from the cervix to the vulva. The internal lining of the vagina consists of stratified squamous epithelium. Beneath this lining is a layer of smooth muscle, which may contract during sexual intercourse and when giving birth. Beneath the muscle is a layer of connective tissue called adventitia. Although there is wide anatomical variation, the length of the unaroused vagina of a woman of child-bearing age is approximately 6 to 7.5 cm (2.5 to 3 in) across the anterior wall (front) and 9 cm (3.5 in) long across the posterior wall (rear). During sexual arousal the vagina expands in both length and width. Its elasticity allows it to stretch during sexual intercourse and during birth to offspring. The vagina connects the superficial vulva to the cervix of the deep uterus. The vagina has three functions: To serve as the passage for sperm and for the fetus during birth To provide passage for the menstrual products from the uterine endometrium to the outside of the body To protect against trauma from sexual intercourse and infection from pathogenic organisms. UTERUS The uterus, or womb, is the main female internal reproductive organ. The inner lining of the uterus is called the endometrium, which grows and changes during the menstrual cycle to prepare to receive a fertilized egg. The layer sheds at the end of every menstrual cycle if fertilization does not happen. The uterus is lined with powerful muscles to push the child out during labor. The uterus consists of a body and a cervix.The cervix protrudes into the vagina. The uterus is held in position within the pelvis by condensations of endopelvic fascia, which are called ligaments. These ligaments include the pubocervical, transverse. cervical ligaments cardinal ligaments, and the uterosacral ligaments. It is covered by a sheet-like fold of peritoneum, the broad ligament. The uterus is essential in sexual response by directing blood flow to the pelvis and to the external genitalia, including the ovaries, vagina, labia, and clitoris. The reproductive function of the uterus is to accept a fertilized ovum which passes through the utero-tubal junction from the fallopian tube. It implants into the endometrium, and derives nourishment from blood vessels which develop exclusively for this purpose. The fertilized ovum becomes an embryo, attaches to a wall of the uterus, creates a placenta, and develops into a fetus (gestates) until childbirth. Due to anatomical barriers such as the pelvis, the uterus is pushed partially into the abdomen due to its expansion during pregnancy. Even during pregnancy the mass of a human uterus amounts to only about a kilogram (2.2 pounds). 6 | P a g e
The nulliparous uterus resembles an inverted pear and consists of two main parts: the body and the cervix. The body is twice as long as the cervix, whereas the converse is true in the newborn. The body includes the fundus, which is the portion that lies superior and anterior to the openings of the uterine tubes. The body is usually tilted anteriorly onto the bladder which is separated from the uterus by the uterovesical pouch. Superior and posterior, the body is separated from the rectum by the recto- uterine pouch , which usually contains coils of ileum. Right and left margins are anchored to the broad ligaments. The region between the body and cervix is referred to as the isthmus: during pregnancy, it is known as the "lower uterine segment." The cavity of the isthmus was formerly called the "internal os." The cervix extends inferiorward and posteriorward and usually forms approximately a right angle with the vagina. As the bladder fills, the uterus tends to become retroverted. The cervix may be considered in two parts: (1) a supravaginal portion superior to the limits of the vagina and (2) a vaginal portion, which projects into the cavity of the vagina. The cavity of the uterine body, which is somewhat triangular in coronal perspective, is slit-like in sagittal section. The canal of the cervix communicates with the vagina by the external os, which is bounded by anterior and posterior lips. The entire uterine cavity can be demonstrated radiographically by hysterosalpingography. The uterus can be palpated bimanually. Dilatation (of the cervical canal) and curettage (scraping of the uterine lining) are performed for diagnostic or therapeutic purposes. The layers, from innermost to outermost, are as follows: Endometrium The lining of the uterine cavity is called the "endometrium". It consists of the functional endometrium and the basal endometrium from which the former arises. Damage to the basal endometrium results in adhesion formation and/or fibrosis (Asherman's syndrome). In all placental mammals, including humans, the endometrium builds a lining periodically which is shed or reabsorbed if no pregnancy occurs. Shedding of the functional endometrial lining is responsible for menstrual bleeding (known colloquially as a "period" in humans, with a cycle of approximately 28 days, +/-7 days of flow and +/-21 days of progression) throughout the fertile years of a female and for some time beyond. Depending on the species and attributes of physical and psychological health, weight, environmental factors of circadian rhythm, photoperiodism (the physiological reaction of organisms to the length of day or night), the effect of menstrual cycles to the reproductive function of the uterus is subject to hormone production, cell regeneration and other biological activities. The menstrual cycles may vary from a few days to six months, but can vary widely even in the same individual, often stopping for several cycles before resuming. Marsupials and monotremes do not have menstruation. Myometrium The uterus mostly consists of smooth muscle, known as "myometrium." The innermost layer of myometrium is known as the junctional zone, which becomes thickened in adenomyosis.
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Parametrium The loose connective tissue around the uterus. Perimetrium The peritoneum covering of the fundus and ventral and dorsal aspects of the uterus.
THE CERVIX The cervix is the opening to the uterus. It varies in diameter from 1 to 3 millimeters, depending upon the time in the menstrual cycle when the measurement is taken. The cervix is sometimes plugged with cervical mucous to protect the cervix from infection; during ovulation, this mucous becomes a thin fluid to permit the passage of sperm. The cervical mucus has three functions: To lubricate the vaginal canal To act as a bacteriostatic agent To provide an alkaline environment to shelter deposited sperm from the acidic vagina At ovulation, cervical mucus is clearer, thinner, more profuse, and more alkaline than at other times. UTERINE LIGAMENTS Broad Ligaments. From each side of the uterus, the pelvic peritoneum extends laterally, downward, and backward. A double fold of pelvic peritoneum forms the layers of the broad ligament, enclosing the uterus. These layers separate to cover the floor and sides of the pelvis. The uterine tube is situated within the free upper border of broad ligament. The part of the broad ligament lying immediately below the uterine tube is termed the mesosalpinx. The ovary lies behind the broad ligament. Round Ligaments. These fibromuscular bands are attached to the uterus. Each round ligament passes forward and laterally between the layers of the broad ligament to enter the deep inguinal ring. Uterosacral Ligaments. These are a posterior continuation of the peritoneal tissue, which forms the cardinal ligaments. The ligaments pass posteriorly to the sacrum on either side of the rectum. Ovarian ligament is a rounded, cord-like thickening of the broad ligament, located at its lower end, where it is attached to the uterus. It, along with the other ovarian ligaments, attaches to the ovaries and help hold them in position. The largest of these ligaments, formed by a fold of peritoneum, is called the broad ligament. It is also attached to the uterine tubes and to the uterus. At its upper end, the ovary is held by a small fold of peritoneum called the suspensory ligament, which contains the ovarian blood vessels and nerves. At its lower end, it is attached to the uterus by a rounded, cord-like thickening of the broad 8 | P a g e
ligament, called the ovarian ligament. The peritoneum is a two-layered membrane that supports the abdominal organs, produces lubricating fluid that allows the organs to flow smoothly over each other, and protects against infection. Cardinal Ligament. It is located at the base of the broad ligament of the uterus. Importantly, it contains the uterine artery and uterine vein. There is a pair of cardinal ligaments in the female human body.It attaches the cervix to the lateral pelvic wall at the ischial spine, and is continuous externally with the fibrous tissue that surrounds the pelvic blood vessels. It thus provides support to the uterus. Infundibulopelvic Ligament. It suspends and supports the ovaries. Arising from the outer third of the broad ligament, the infundibulopelvic ligament contains the ovarian vessels and nerves.
FALLOPIAN TUBES The fallopian tubes stretch from the uterus to the ovaries and measure about 8 to 10 cm (4 to 6 inches) in length. The ends of the fallopian tubes lying next to the ovaries feather into ends called fimbria (Latin for "fringes" or "fingers"). Millions of tiny hair-like cilia line the fimbria and interior of the fallopian tubes. The cilia beat in waves hundreds of times a second catching the egg at ovulation and moving it through the tube to the uterine cavity. Other cells in the tube's inner lining or endothelium nourish the egg and lubricate it's path during its stay inside the fallopian tube. Once inside the fallopian tube, the egg and sperm meet and the egg is fertilized. If an egg doesn't become fertilized within 24 to 36 hours after ovulation, it will deteriorate and be removed by the body's immune system like any other dead cell in the body. Segments of the fallopian tube The fallopian tube is not just a passive pipe or a conduit, but an active organ with its separate locations performing separate functions. Starting from the ovarian end (fimbria) and proceeding toward the uterus, these are the: Fimbrial segment - faces the ovary Infundibular segment - funnel shaped segment behind the fimbria Ampullary segment - wide middle segment Isthmic segment - narrow muscular segment near the uterus Interstitial segment - passes through the uterine muscle into the uterine cavity Role of the fallopian tubes in fertilization and implantation A muscular ligament called the fimbria ovarica joins the fimbrial end of the tube and the ovary. At the time of ovulation, the fimbria ovarica contracts to pull the fimbrial end of the tube even closer to the ovary. The beating cilia cells of the fimbria capture the egg and draw it into the fallopian tube. Muscular contractions of the tube and the cilia of its inner lining move the egg and sperm toward the uterus. The interstitial segment of the tube acts like a muscle sphincter and prevents the egg from being 9 | P a g e
released into the uterus until it is ready for implantation. During its week-long journey through the fallopian tube, a fertilized egg is nourished by cells lining the tubal lumen while the egg divides many times. When the outer membrane of the egg breaks apart, allowing the embryo to "hatch", it is able to implant itself into the uterine lining or endometrium. Implantation usually occurs about 1 week after ovulation. OVARIES The ovaries are 2 small glands located on either side of a woman's uterus. They are part of the female reproductive system that are responsible for the storing and releasing of the eggs (ova), which can develop into a fetus if fertilized by a male's sperm. Approximately once a month, about 2 weeks before a woman's next period ovulation occurs when an egg is released from one of her ovaries The ovaries also produce female sex hormones, estrogen and progesterone, which help control the menstrual cycle, breast development, and other functions. FEMALE HORMONES
a. Estrogen increases myometrial contractility in both the uterus and fallopian tubes increases uterine sensitivity to oxytocin inhibits FSH production
b. Progesterone stimulates LH production secreted by the corpus luteum found in greatest amounts in the secretory phase of the menstrual cycle decreases uterine motility and contractility caused by estrogens preparing the uterus for implantation after the ovum is fertilized hormone of pregnancy vaginal epithelium proliferates and the cervix secretes thick, viscous mucus prepares the breast for lactation
c. Prostaglandin oxygenated fatty acids produced by the cells of the endometrium also classified as hormones 2 primary types PGE- relaxes smooth muscles; potent vasodilator PGF- increases contractility of muscles and arteries; potent vasoconstrictor
OVARIAN CYCLE a. Follicular phase (days 1 - 14) Hypothalamus secretes gonadotropin releasing hormone(GnRH) GnRH stimulate anterior pituitary gland to secrete FSH/LH 10 | P a g e
FSH is primarily responsible for the maturation of the ovarian follicle
b. Luteal phase (days 15 - 28 in a 28 day cycle) Release of ovum LH: corpus luteum develops from ruptured follicle secretion of progesterone increases fertilized ovum able to implant into endometrium secretion of human chorionic gonadotropin (hCG) absence of fertilization corpus luteum degenerates
MENSTRUAL CYCLE
Menstruation is cyclic uterine bleeding in response to cyclic hormonal changes. Menstruation occurs when the ovum is not fertilized and begins about 14 days after ovulation in a 28-day cycle. The menstrual discharge referred to as menses is composed of blood mixed with fluid, cervical and vaginal secretions, bacteria, mucus, leukocytes, and other cellular debris. The menstrual discharge is dark red and has a distinctive odor. Menstrual parameters vary greatly among individual. Emotional and physical factors such as illness, excessive fatigue, stress or anxiety, and vigorous exercise programs can alter the cycle interval. The duration of menses is from 2-8 days, with the blood loss averaging 30 ml. The uterine (menstrual) cycle has four phases.
1. Menstrual phase Menstruation occurs during this phase. Also, in this phase, some endometrial areas are shed, while others remain. Some of the remaining tips of endometrial glands begin to regenerate. The endometrium is in a resting state after menstruation. Estrogen levels are low, and the endometrium is 1 to 2 mm deep. During this part of the cycle, the cervical mucosa is scanty viscous, and opaque.
2. Proliferative phase This phase begins when the endometrial glands enlarge, becoming twisted and longer in response to increasing amounts of estrogen. The blood vessels become prominent and dilated, and the endometrium increases in thickness six to eightfold. This gradual process reaches its peak just before ovulation. The cervical mucosa becomes thin, clear, watery, and more alkaline, making the mucosa more favorable to spermatozoa. As ovulation nears, the cervical mucosa shows increased elasticity, called spinnbarkeit. At ovulation, the mucus will stretch more than 5 cm. The cervical mucosa pH increases from below 7.0 to 7.5 at the time of ovulation. On microscopic examination, the mucosa shows a characteristic ferning pattern. This fern pattern is useful in assessing ovulation time.
3. Secretory phase The secretory phase follows ovulation. The endometrium, under estrogenic influence, undergoes slight cellular growth. Progesterone, however, causes such marked swelling and growth that the epithelium is warped into folds. The amount of 11 | P a g e
tissue glycogen increases. The glandular epithelial cells begin to fill with cellular debris, become twisted, and dilate. The glands secrete small quantities of endometrial fluid in preparation for a fertilized ovum. The vascularity of the entire uterus increases greatly, providing a nourishing bed for implantation. If implantation occurs, the endometrium, under the influence of progesterone, continues to develop and become even thicker.
4. Ischemic phase If fertilization does not occur, the ischemic phase begins. The corpus luteum begins to degenerate, and as a result both estrogen and progesterone levels fall. Areas of necrosis appear under the epithelial lining. Extensive vascular changes also occur. Small blood vessels rupture, and the spiral arteries constrict and retract, causing a deficiency of blood in the endometrium, which becomes pale. This ischemic phase is characterized by the escape of blood into the stromal cells of the uterus. The menstrual flow begins, thus beginning the menstrual cycle again. After menstruation, the basal layer remains, so that the tips of the glands can regenerate the new functional endometrial layer.
V. GYNECOLOGIC DISORDERS: A. Menstrual Dysfunctions: 1. Amenorrhea absence of menstruation anytime between puberty and menopause (not a disease but a symptom) a. Primary failure of menstruation to appear initially at puberty b. Secondary cessation of menstruation after menarche Physiologic normal absence before puberty, during pregnancy, lactation and menopause Cryptomenorrhea or Pseudomenorrhea menstruation occurs but does not appear externally because of obstruction in the lower genital organs Pathological due to some pathologic diseases of the reproductive system
2. Oligomenorrhea reduction in frequency of menstruation or prolongation of interval abnormally, usually from 38 days to 3 months
3. Polymenorrhea interval is shortened or more frequent occurrence of menses, usually every 20 days
4. Hypomenorrhea scanty menstrual flow without relation to frequency
6. Metrorrhagia bleeding or spotting without obvious relation to the menstrual cycle; also known as intermenstrual bleeding
7. Dysmenorrhea painful menstruation with spastic, crampy, and congestive pains a. Primary or Intrinsic onset of pain early in menstrual life with inherent or congenital causes 12 | P a g e
b. Secondary or Acquired (Extrinsic) onset of pain several years after menarche Membranous Dysmenorrhea caused by the removal of the endometrium as one piece instead of breaking off or sloughing off; also known as endometrial cast
Causes: a. Psychogenic unstable nervous system or psychic trauma especially when it occurs during the menstrual period; lack of knowledge about significance and normality of menstrual functions b. Constitutional results from disease condition such as anemia, overwork or fatigue c. Obstructive or Anatomical caused by cervical lesions, stenosis or acute anteflexion of the uterus d. Endocrine Factors increased estrogen which is a normal stimulant of uterine contractility
Treatment: a. Endocrine Therapy 1. use of estrogen inadequate dosage in early part of the cycle to convert ovulatory cycle to unovulatory - inhibition of ovulation brings about relief in pain 2. use of progesterone to suppress ovulation, the drug is given during the first 25 days of the cycle b. Pre-sacral Neurectomy - surgical removal of the presacral plexus the group of nerves that conducts the pain signal from the uterus to the brain. c. Treatment during attacks: 1. local use of heat 2. analgesics 3. antispasmodics d. Psychotherapy
Possible causes of menstrual dysfunctions a. Neurogenic organic lesions or idiopathic hypothalamic dysfunction b. Pituitary insufficiency of hormones, tumors, or congenital defect c. Psychogenic minor or major psychosis d. Chronic illness e. Metabolic diseases of the pancreas, thryroid, and adrenals f. Nutritional disturbances like malnutrition g. Ovarian tumors or congenital defects h. Congenital causes like imperforate hymen, absence of vaginal septum (gynatresis) i. Traumatic stenosis of vagina or cervix due to trauma
General Methods of Treatment - each patient must be treated according to etiologic factor: a. Steroid Therapy designed to trigger pituitary functions 13 | P a g e
b. Gonadotropic Therapy designed to replace pituitary hormones c. Clomiphene Therapy stimulate pituitary activity through the hypothalamus d. Hypothalamic Hormone Stimulation directly stimulates synthesis and release fo pituitary and gonadotropins (still under research) e. Good Nutrition
B. Dysfunctional Uterine Bleeding (DUB) - abnormal bleeding form the uterus associated with tumor and inflammations. It is apt to occur at the extremes of menstrual life. - major cause is increase in the endometrial lining of the uterus (endometrial hyperplasia)
C. Unovulatory Bleeding - follicle develops but instead of maturation becomes cystic and then degenerates
D. Abnormal Menstruation Precacious appearance of menarche early in childhood; usually under 9 years of age. There is a question whether they can be really called as menstruation.
VI. USUAL GYNECOLOGIC PROCEDURES: A. Schillers test a preliminary test for cancer of the uterine cervix in which the cervix is painted with an aqueous solution of iodine and potassium iodide and which shows up healthy tissue by staining it brown and possibly cancerous tissue as white or yellow due to its failure to take up the stain because of a deficiency of glycogen in the cells
B. Papanicolau test a method or a test based on it for the early detection of cancer especially of the uterine cervix that involves staining exfoliated cells by a special technique which differentiates diseased tissue subjects: women 20 years above sexually active women: done regularly preparations: no sexual activity in the preceding 24 hours no lubricant use no vaginal tablets for 2-3 nights before no perennial douche before the exam procedure: aspirate or swab vaginal secretions from the posterior fornix and make a smear on the glass with light rolling motion. Do not let smear become dry, immerse immediately in a fixing solution of ethanol 95%. Results: has 90-95% accuracy for cervical Ca 14 | P a g e
70-75% accuracy for severe dysplasia 80% accuracy for endometrial Ca Classification: Class 1 absence of atypical or abnormal cells Class 2 atypical cytology but no evidence of malignancy Class 3 cytology suggestive but not conclusive of malignancy Class 4 cytology strongly suggest Ca Class 5 cytology is conclusive of Ca
C. Culdoscopy Visualization of the internal reproductive organs by inserting a tubular lighted instrument (culdoscope) through an incision made in the posterior fornix of the vagina into the cul-de-sac of Douglas Preparation: Knee-chest Home-care instructions o No douches and sexual activity for 1 week o Watch out for complications like infection, hemorrhage, and air embolism o Incision should heal rapidly
D. Laparoscopy Abdomen is insufflated with CO2 and a trocar is introduced through the lower portion of the umbilicus. A laparoscope is inserted and pelvic organs are visualized. This is a diagnostic aid to determine ectopic pregnancy, inflammatory disease and ovarian neoplasms
E. Hystero-Salpingogram X-ray study of the uterus and the fallopian tubes after the injection of a contrast medium through the cervix via a cannula (indigo-carmine dye) Purposes: Study problems of sterility Evaluate tubal patency Determine the presence of uterine pathology Position: Lithotomy Result: If tubes are patent the dye can be visualized passing out the fimbriated end of the fallopian tubes
F. Rubins test Determine tubal patency, CO2 is passed through the cervix into the uterus and tubes. If patent, gas will pass through the fimbriated ends of the fallopian tubes into the peritoneal cavity and will give a sensation of fullness and spasmodic shoulder pains due to severe irritation from the gas
G. Sim-Hunners test Post-coital exam A specimen of seminal fluid from posterior-fornix and cervical canal is aspirated 2-4 hours after coitus 15 | P a g e
Purposes Test for compatibility of sperms with cervical mucus Determine husbands ability to deposit normal motile sperms in sufficient amount
H. Semen analysis Examination of the semen for number and motility
I. Ultrasound Simple, safe, and inexpensive procedure which causes or uses soundwaves of a transducer and scan oscilloscope Purpose: to determine tumor or cysts or retroperitoneal masses Limitations technical difficulty in fat or obese patients could be altered by gas interference
J. Computerized Tomography Instead of just a single X-ray source and film, there is an x-ray source moving around the patient with special detectors opposite the x-ray source. The computer translates the x-ray film taken on the patient and projects it into the screen.
VII. DIFFERENTIAL DIAGNOSES: Other disease conditions that may present with the signs and symptoms manifested by the client in the case scenario given include: *N.B: signs or symptoms in bold are those that are manifested by client in the scenario given
Acute appendicitis Appendicitis is a condition characterized by inflammation of the appendix. Signs and symptoms of appendicitis include presence of right lower quadrant pain, and occasional febrile episodes.
Pelvic Inflammatory Disease Pelvic inflammatory disease (PID) is an infectious and inflammatory disorder of the upper female reproductive tract, including the uterus, fallopian tubes, and adjacent pelvic structures. PID is initiated by infection that ascends from the vagina and cervix. The most common presenting complaint is lower abdominal pain.
Ovarian Torsion Ovarian torsion (adnexal torsion) is an infrequent but significant cause of acute lower abdominal pain in women. This condition is usually associated with reduced venous return from the ovary as a result of stromal edema, internal hemorrhage, hyperstimulation, or a mass. The ovary and fallopian tube are 16 | P a g e
typically involved. Other signs presented by patient indicative of diagnosis stated include fever, nausea, and vomiting.
Endometriosis Endometriosis is defined as the presence of normal endometrial mucosa (glands and stroma) abnormally implanted in locations other than the uterine cavity. This tissue, possessing the same steroid receptors as normal endometrium, is capable of responding to the normal cyclic hormonal milieu. Microscopic internal bleeding, with the subsequent inflammatory response, neovascularization, and fibrosis formation, is responsible for the clinical consequences of this disease. Symptoms include dysmenorrhea, heavy or irregular bleeding, pelvic pain, lower abdominal pain, back pain, dyspareunia, dyschezia (pain on defecation), bloatedness, nausea, and vomiting.
Ascites Ascites describes the condition of pathologic fluid collection within the abdominal cavity. As more fluid accumulates, increased abdominal girth and size are commonly seen. Abdominal pain, discomfort, and bloating are also frequently seen as ascites becomes larger. Shortness of breath or dyspnea can also happen with large ascites due to increased pressure on the diaphragm and the migration of the fluid across the diaphragm causing pleural effusions (fluid around the lungs). Other signs include bulging flanks with (+) fluid wave. Disease conditions that predisposes client to develop ascites include hypertension.
Diverticular disease Diverticula are small mucosal herniations protruding through the intestinal layers and the smooth muscle along the natural openings created by the vasa recta or nutrient vessels in the wall of the colon. These herniations create small pouches lined solely by mucosa. Diverticulitis is defined as an inflammation of one or more diverticula. In simple diverticulitis, localized abdominal tenderness in the area of the affected diverticula and fever are common findings. Right lower quadrant tenderness, mimicking acute appendicitis, can occur in right-sided diverticulitis. In complicated diverticulitis with abscess formation, a tender palpable mass may be felt on physical examination. Peritonitis due to free perforation results in generalized tenderness with rebound and guarding on abdominal examination. The abdomen may be distended and tympanic to percussion. Bowel sounds can be diminished or absent.
Inflammatory Bowel Disease Inflammatory bowel disease (IBD) is an idiopathic disease, probably involving an immune reaction of the body to its own intestinal tract. The 2 major types of IBD are ulcerative colitis (UC) and Crohn disease (CD). As the name suggests, ulcerative colitis is limited to the colon. Crohn disease can involve any segment of the gastrointestinal (GI) tract from the mouth to the anus. Fever, tachycardia, dehydration, and toxicity may occur in patients with IBD. Signs of localized 17 | P a g e
peritonitis may also occur, although abdominal tenderness is common. Patients with Crohn disease may develop a mass in the right lower quadrant. Common presenting signs of complications include occult blood loss and low-grade fever, weight loss, and anemia.
Large Bowel or Small Bowel Obstruction A bowel obstruction happens when either the small or large intestine is partly or completely blocked. The blockage prevents food, fluids, and gas from moving through the intestines in the normal way. The blockage may cause severe pain that comes and goes. Obstruction to the bowels is commonly manifested by abdominal tenderness, abdominal distention, vomiting, and bloatedness.
Benign tumors of the uterus a. Endometrial polyps Endometrial polyps are small, soft growths on the lining of the uterus (endometrium) which are also known as uterine polyps. These endometrial polyps can irritate the surrounding tissues causing spotting or vaginal bleeding. Endometrial polyps can occur alone or in groups. Most occurrences of endometrial polyps are benign in nature.
The exact cause for the occurrences of endometrial polyps is still unknown but polyps are said to form when there is an overgrowth of tissue in the uterine lining. Growth of endometrial polyps also appears to be affected by hormone levels and grow in response to circulating estrogen. Endometrial polyps often cause no symptoms but if symptoms do occur, one of the most common is bleeding. This includes irregular menstrual bleeding, bleeding between menstrual periods, excessive heavy menstrual periods, vaginal bleeding after menopause and infertility. Endometrial polyps usually occur in women ages 40-50 years old. Risk factors for endometrial polyps include obesity, high blood pressure, history of cervical polyps and also women taking hormone replacement therapy.
b. Myomata or fibroids Myomata or fibroids are benign swellings in the muscle of the womb that occur in women of all ages and races. It is the most common benign tumor of the uterus which is estimated to be found in 20% of women over 35 years of age. Frequent spoken as fibroids which can be either single or multiple, microscopic or big with weight as high as 410 lbs. It is a dense well-encapsulated nodule composed chiefly of unstriped muscle and fibroid connective tissue.
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A common cause for myomata is hormonal changes (estrogen). Myomas do not develop before the body begins producing estrogen. Myomas tend to grow very quickly during pregnancy when the body is producing extra estrogen. Once menopause has begun, myomas generally stop growing and can begin to shrink due to the loss of estrogen. A predisposing factor for myomata is nulligravidity.
Symptoms includes palpable mass in the lower abdomen or abdominal enlargement, bleeding, pain which can be assumes as dysmenorrheal or sensation of weight and bearing down and pressure effects manifested as frequency in urination or dysuria and constipation.
Types of Myomata or fibroids according to placement: a) Submucous myoma - develops beneath the endometrium - either pedunculated (attached to a pedicle) or wandering submucous (goes from one site to another) b) Interstitial or intramural myoma - situated in the muscular wall with no close proximity to either the mucosa or the serosa c) Subserous or subperitoneal - growth out between the folds of the broad ligament which may impede on the ureter and iliac vessels d) Intraligementary - implants on the pelvic ligaments e) Cervical - rare and obstructs the cervix Secondary changes: a. Hyaline degeneration most common secondary change which involves the broad areas of the tumor causing liquification when the tumor outgrows the blood supply b. Cystic degeneration enlargement of the lymphatics c. Calcification occurs when there is circulatory disturbances which converts the mass into a hard, stony mass d. Infection and suppuration commonly occurs in the submucous myoma which is prone to thinning and ulceration of the underlying mucosa giving access to organisms from the uterine canal that can cause infection e. Necrosis due to impairment of the blood circulation f. Fatty degeneration rare but may occur with hyaline degeneration g. Sarcomatous degeneration rare to occur 19 | P a g e
h. Acute torsion of the pedicle with acute disruption of the blood supply resulting to gangrenous changes in the myoma.
VIII. PATHOPHYSIOLOGY
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IX. MEDICATIONS Amlodipine anti-hypertensive, Ca channel blocker Metformin for type 2 DM, oral anti-hyperglycemic
X. LABORATORY PROCEDURES *done to the patient
MAMMOGRAPHY specific type of imaging low dose x-ray system examine the breast mammogram exam itself early detection and diagnosis Recent advances: DIGITAL MAMMOGRAPHY Also called full-field digital mammography (FFDM) solid-state detectors that convert x-rays into electrical signals similar to digital cameras seen on a computer screen or printed on special film similar to conventional mammograms patients POV same as conventional COMPUTER-AIDED DETECTION digitized mammographic image that can be obtained from either a conventional film mammogram or a digitally acquired mammogram computer software then searches for abnormal areas of density, mass, or calcification that may indicate the presence of cancer highlighted parts BREAST TOMOSYNTHESIS 3-D breast imaging x-ray tube and imaging plate move during the exposure creates a series of thin slices through the breast that allow for improved detection of cancer and fewer patients recalled for additional imaging BREAST NODULE BIOPSY removes a sample of breast tissue seen under microscope to know if (+) breast cancer cancer cells usually done to check a lump found during a breast examination or a suspicious area found on a mammogram, ultrasound, or magnetic resonance imaging (MRI) Types: FINE-NEEDLE ASPIRATION BIOPSY - a thin needle is inserted into a lump and removes a sample of cells or fluid CORE NEEDLE BIOPSY - a needle with a special tip is inserted and removes a sample of breast tissue about the size of a grain of rice 22 | P a g e
VACUUM-ASSISTED CORE BIOPSY - done with a probe that uses a gentle vacuum to remove a small sample of breast tissue - The single small cut doesn't require stitches and leaves a very small scar. OPEN (SURGICAL) BIOPSY - a small cut is done in the skin and breast tissue to remove part or all of a lump - This may be done as a first step to check a lump or if a needle biopsy doesn't provide enough information If needed, may use ultrasound or MRI to guide the biopsy needle May use a computer to locate the exact spot for the biopsy sample from mammograms that have been taken from two angles (stereotactic needle biopsy) A fine wire, clip, or marker also may be used to mark the site Only reliable way to see if cancer cells are present Check! If the patient: Is taking any medicines. Is allergic to any medicines, including anesthetics. Is allergic to latex. Has any bleeding problems or is taking blood thinners, such as warfarin (Coumadin) or clopidogrel (Plavix). Is or might be pregnant. XI. MEDICAL AND SURGICAL MANAGEMENT In general, the course of treatment is determined by the stage of the cancer. Stages range from I to IV based on the cancer's specific characteristics, such as whether it has spread beyond the ovaries.
A. CHEMOTHERAPEUTIC DRUGS Carboplatin: An anticancer drug ("antineoplastic" or "cytotoxic") chemotherapy drug. Carboplatin is classified as an "alkylating agent." Indication: - Carboplatin is used to treat ovarian cancer. - Carboplatin is also used for other types of cancer, including lung, head and neck, endometrial, esophageal, bladder, breast, and cervical; central nervous system or germ cell tumors; osteogenic sarcoma; and as preparation for a stem cell or bone marrow transplant. Side effects: - Low blood counts (nadir) - n/v - taste changes - hair loss - weakness - blood test abnormalities
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Docetaxel: An anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as a "plant alkaloid," a "taxane" and an "antimicrotubule agent." Indication: - Approved in treatment of breast cancer, non-small cell lung cancer, advanced stomach cancer, head and neck cancer and metastatic prostate cancer. - Also being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers, soft tissue sarcoma and melanoma. Side effects - Low white blood cell count. (This can increase your risk for infection) - Low red blood cell count (anemia)Fluid retention with weight gain, swelling of the ankles or abdominal area. - Peripheral neuropathy (numbness in your fingers and toes) may occur with repeated doses. This should be reported to your healthcare provider. - Nausea - Diarrhea - Mouth sores - Hair loss - Fatigue and weakness - Infection - Nail changes (Color changes to your fingernails or toenails may occur while taking docetaxel. In extreme, but rare, cases nails may fall off. After you have finished docetaxel treatments, your nails will generally grow back) (see skin problems).
B. SURGICAL MANAGEMENT Surgery is the main treatment for ovarian cancer. It is used to treat all stages of ovarian cancer. For earlier stage ovarian cancer, it may be the only treatment.
Surgery involves: 1. Removal of both ovaries and fallopian tubes (bilateral salpingo-oophorectomy) 2. Partial or complete removal of the omentum, the fatty layer that covers and pads organs in the abdomen 3. Oophorectomy, a surgical procedure to remove one or both ovaries. The ovaries contain eggs and produce hormones that control your menstrual cycle. Oophorectomy can be done alone, but it is often done as part of a larger surgery to remove the uterus (hysterectomy) in women who have undergone menopause. Oophorectomy is also commonly combined with surgery to remove the nearby fallopian tubes (salpingectomy), since they share a common blood supply with the ovaries. When combined, the procedure is called salpingo- oophorectomy. 24 | P a g e
4. Examination, biopsy, or removal of the lymph nodes and other tissues in the pelvis and abdomen
Following surgery, women with higher-stage tumors may receive chemotherapy. It is used to treat any remaining disease and can also be used if there is recurrent cancer. Chemotherapy is a drug treatment that uses powerful chemicals to kill fast- growing cells in the body. Though chemotherapy is an effective way to treat many types of cancer, chemotherapy treatment also carries a risk of side effects. Some chemotherapy side effects are mild and treatable, while others can cause serious complications.
After surgery and chemotherapy, patients should have: 1. A physical exam (including pelvic exam) every 2 - 4 months for the first 2 years, followed by every 6 months for 3 years, and then annually 2. A CA-125 blood test at each visit if the level was initially high 3. A computed tomography (CT) scan of the chest, abdomen, and pelvic area and a chest x-ray.
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XII. NURSING CARE PLANS: Assessement Nursing Diagnosis Scientific Rationale Objectives Planning Scientific Rationale Evaluation With abdominal enlargement With dyspnea Bloatedness Nasal flaring with intercostals retraction RR: 26 bpm Lagging on the left hemi- diaphragm Decrease tactile fremiti on the left Decreased breath sounds on left lung field AC: 68 cm (+) fluid wave Ineffective breathing pattern related to compression of diaphragm secondary to peritoneal fluid accumulation Ineffective breathing pattern happens when the inspiration and/or expiration does not provide adequate ventilation.
The increasing amount of fluid in the peritoneal cavity presses the diaphragm limiting lung expansion therefore leading to ineffective breathing pattern. By the end of 4 hours of nursing intervention, the patient should be able to:
demonstrate proper deep breathing exercises
show an improvement in her respiratory pattern as evidenced by the absence of signs and symptoms of hypoxia
verbalize awareness of causative factors
Independent: 1. Encourage adequate rest periods between activities
2. Elevate HOB and/or have client sit up in a chair, as appropriate
3. Encourage slower/ deeper respirations such as the use of the pursed-lip technique
4. Maintain a calm attitude when dealing with client
5. Advise to avoid overeating or gas-forming foods
1. To limit fatigue and decrease oxygen demand.
2. To promote physiological/ psychological ease of maximal inspiration
3. To promote optimum lung expansion and effective respiration.
4. Limits anxiety level and decrease oxygen demand.
5. May cause abdominal distention
At the end of 4 hours of nursing intervention, the patient was able to:
Establish a normal / effective respiratory pattern as evidenced by the absence of sign and symptoms of hypoxia Demonstrated proper breathing pattern Verbalized awareness of causative factors 26 | P a g e
6. Stress importance of good posture and effective use of accessory muscles
7. Discuss the possible cause of difficulty breathing
Dependent: 8. Hook to oxygen as ordered
9. Monitor oxygen saturation with pulse oximeter as indicated.
10. Medicate with analgesics as appropriate
6. To maximize respiratory effort
7. Decreases anxiety level
8. To provide proper oxygenation.
9. To verify maintenance/ improvement in O2 saturation
10. To promote deeper respiration and decrease oxygen demand. 27 | P a g e
Assessment Diagnosis Scientific Rationale Objective Intervention Rationale Evaluation Grade 2 bipedal edema (+) venous congestion BP = 170 / 90 PP = 80 MAP = 117 PR = 113 HPN for 8 years DM for 2 years Ineffective tissue perfusion related to decreased blood oxygen supply secondary to increased peripheral vascular resistance In order to ensure maximal organ functioning, adequate blood supply is necessary. In patients with hypertension, there is increased peripheral vascular resistance due to vasoconstriction. This is further worsened by diabetes mellitus wherein blood becomes viscous thus requiring a greater effort for the heart to pump blood and deliver systemic supply. When there is ineffective tissue perfusion, the body tries to compensate by increasing blood pressure and MAP, and widening the pulse pressure.
Short-term After 5 hours of nursing interventions, the patient will be able to:
Manifest a decrease in the severity of edema Show signs of improved perfusion as seen by a decrease in BP, MAP, and PP
Long-term After the 2 weeks of nursing intervention, the patient will be able to:
Demonstrate adequate perfusion, as evidenced by stable vital signs, palpable pulses, good capillary refill, usual mentation, and individually adequate urinary output. 1. Elevate legs but maintain semi- high fowlers position
2. Apply warm compress to extremity with edema
3. Turn client and encourage frequent AROM exercises.
4. Assist with and instruct in foot and leg exercises and ambulate as soon as able.
5. Note erythema, swelling of extremity, or reports of sudden chest pain with dyspnea
1. Helps lessen edema and direct circulation to vital organs
2. Doing this results to vasodilation that will help lessen edema
3. Prevents stasis of secretions and respiratory complications
4. Movement enhances circulation and prevents stasis complications.
5. May be indicative of development of thrombophlebiti s and pulmonary embolus
Short-term After 2 hours of nursing interventions, the patient was able to:
Manifest a decrease in the severity of edema Show signs of improved perfusion as seen by a decrease in BP, MAP, and PP
Long-term After the 2 weeks of nursing intervention, the patient was be able to:
Demonstrate adequate perfusion, as evidenced by stable vital signs, palpable pulses, good capillary refill, usual mentation, and adequate urinary output.
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Be free of edema and signs of thrombus formation. 6. Educate the client regarding underlying disease processes that may have contributed to her problem
6. Promotes better understanding of disease condition and helps client accept implications of disease Be free of edema and signs of thrombus formation. 29 | P a g e
Assessment Diagnosis Scientific Rationale Objective Intervention Rationale Evaluation (+) progressive weight loss Irregularities in menstruation Abdominal enlargement Anorexia Early satiety Bloatedness Epigastric pain Nausea Vomiting Progressive abdominal enlargement Pain RLQ BMI = 15 Bulging planks (+) fluid wave AC = 68cm Imbalanced Nutrition: Less than body requirement s related to poor food intake secondary to disease process Abdominal enlargement causes compression of the GI tract which yields to early satiety, bloatedness, and epigastric pain. This often leads to loss of appetite causing poor food intake. Furthermore , nausea and vomiting, especially if it happens in increased frequencies, can lead to further depletion of nutrients. Short-term After the shift, the patient will:
Understand health teachings given regarding diet
Able to eat properly with accordance to diet prescribed by the dietician
Verbalize commitment to achieving dietary goals
Long-term After the 4 weeks of nursing intervention, the patient will be able to:
Meet Caloric Requirements
Demonstrate progressive weight 1. Emphasize importance of well- balanced, nutritious intake. Provide information regarding individual nutritional needs
2. Discuss eating habits, including food preferences, intolerances, or aversions
3. Note age, body build, strength, activity/rest level, and other factors that may affect food intake
4. Promote adequate and timely fluid intake
5. Weigh regularly at the same time with the same clothing
6. Encourage small frequent feeding if unable to tolerate large amount of 1. To make client realize importance of maintaining a well-balanced diet to ensure optimal health
2. To appeal to clients likes or dislikes
3. To help in determining nutritional needs
4. To reduce possibility of early satiety
5. To monitor effectiveness of dieting plan
6. Prevents stomach upset and distention which makes food more Short-term After the shift the patient was able to:
Verbalize understanding regarding health teachings given concerning her diet
Eat properly with accordance to diet prescribed by the dietician
Verbalize lifestyle changes to regain appropriate weight
Verbalize commitment to achieving dietary goals
Long-term After the 4 weeks of nursing intervention, the patient was be able to:
Meet Caloric 30 | P a g e
gain
Continuously follow health teachings given regarding diet
Demonstrate BMI >15 or in normal range (18-24.9) food in a single meal
7. Encouraged intake of high-calorie and high-protein foods
8. Limit fiber.
9. Prevent or minimize unpleasant odors and sights
10. Develop consistent, realistic weight goal with client
11. Consult dietician for long term needs
tolerable.
7. To ensure that nutritional needs are met
8. May lead to early satiety
9. May have negative effect on appetite and eating
10. To develop a good, consistent progression of weight gain
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