Classifcation of Wisconsin Breast Cancer Diagnostic

and Prognostic Dataset using Polynomial Neural

Network
A Dissertation Work
Submitted in Partial fulfllment for the award of
Post Graduate Degree of Master of Technology
In Computer Science & Engineering
Submitted to
Rajiv Gandhi Proudyogiki Vishwavidhyalaya,
Bhopal (M.P.)
Submitted By:
Shweta Saxena
0126CS10MT17
Under the Guidance of
Dr. Kavita Burse
Director, OCT, Bhopal.
Department of Computer Science & Engineering
ORIENTAL COLLGEGE OF TECHNOLOGY,
BHOPAL
(Formerly known as Thakral College of Technology, Bhopal)
Approved by AICTE New Delhi & Govt. of M.P.
Afliated to Rajiv Gandhi Proudyogiki Vishwavidhyalaya, Bhopal (M.P.)
Session 2012-13
ORIENTAL COLLGEGE OF TECHNOLOGY, BHOPAL
(Formerly known as Thakral College of Technology, Bhopal)
Approved by AICTE New Delhi & Govt. of M.P. and Afliated to Rajiv
Gandhi Proudyogiki Vishwavidhyalaya Bhopal (M.P.)
DEPARTMENT OF COMPUTER SCIENCE & ENGINEERING
CERTIFICATE
THIS IS TO CERTIFY THAT THE DISSERTATION ENTITLED
Classifcation of Wisconsin Breast Cancer
Diagnostic and Prognostic Dataset using Polynomial
Neural Network BEING SUBMITTED BY Shweta Saxena
IN PARTIAL FULFILLMENT OF THE REQUIREMENT FOR
THE AWARD OF M.TECH DEGREE IN COMPUTER
SCIENCE & ENGINEERING TO ORIENTAL COLLEGE OF
TECHNOLOGY, BHOPAL (M.P) IS A RECORD OF BONAFIDE
WORK DONE BY HIM UNDER MY GUIDANCE.
II

Dr. Kavita Burse Prof. Roopali
Soni
Dire!or "ead o#
Depar!$en!, %&'
(%), Bhopal (%), Bhopal
(Guide)
ORIENTAL COLLGEGE OF TECHNOLOGY, BHOPAL
(Formerly known as Thakral College of Technology, Bhopal)
Approved by AICTE New Delhi & Govt. of M.P. and Afliated to Rajiv
Gandhi Proudyogiki Vishwavidhyalaya Bhopal (M.P.)
DEPARTMENT OF COMPUTER SCIENCE & ENGINEERING
APPROVAL CERTIFICATE
This dissertation work entitled Classifcation of
Wisconsin Breast Cancer Diagnostic and Prognostic
Dataset using Polynomial Neural Network submitted
by Shweta Saxena is approved for the award of degree of
Master of Technology in Computer Science & Engineering.
III
INTERNAL EXAMINER EXTERNAL EXAMINER
Date: Date:
IV
CANDIDATE DECLARATION
I hereby declare that the dissertation work presented in the report
entitled as Classifcation of Wisconsin Breast Cancer Diagnostic
and Prognostic Dataset using Polynomial Neural Network
submitted in the partial fulfllment of the requirements for the award
of the degree of Master of Technology in Computer Science &
Engineering of Oriental College of Technology is an authentic record
of my own work.
I have not submitted the part and partial of this report for the award
of any other degree or diploma.
Date: Shweta
Saxena

(0126CS10MT17)
This is to certify that the above statement made by the candidate is
correct to the best the best of my knowledge.
Dr. Kavita Burse
Director
OCT, Bhopal
(Guide)
V
ACKNOWLEDGEMENT
I would like !o e*press $y deep sense o# respe! and gra!i!ude !owards $y advisor
and guide Dr. Kavita Burse Dire!tor Oriental Colle"e of Te!#nolo"$ who has
given $e an oppor!uni!y !o work under her. &he has +een a ons!an! soure o#
inspira!ion !hroughou! $y work. &he displayed uni,ue !olerane and unders!anding a!
every s!ep o# progress o# !his work and enouraged $e inessan!ly. "er invalua+le
knowledge and innova!ive ideas helped $e !o !ake !he work !o !he #inal s!age. I
onsider i! $y good #or!une work under suh a wonder#ul person.

I e*press $y respe! !o Prof. Roopali Soni %ea& Co'puter S!ien!e
En"ineerin" Depart'ent Oriental Colle"e of Te!#nolo"$ #or her ons!an!
enourage$en! and invalua+le advie in every aspe! o# $y aade$i li#e. I a$ also
!hank#ul !o all #aul!y $e$+ers o# %o$pu!er &iene and 'ngineering Depar!$en! #or
!heir suppor! and guidane.
I a$ espeially !hank#ul !o $y #a!her Mr. Da'o&ar Sa(ena, $y $o!her Mrs.
Nir'ala Sa(ena, and $y loving sis!ers S#i)#a and S#ra&&#a #or !heir love,
sari#ie and suppor! on every pa!h o# $y li#e. I e*!end a speial word o# !hanks !o $y
hus+and Mr. As#is# Sa(ena #or his $oral suppor! and help in ahieving $y ai$.
-as! +u! no! !he leas! I a$ e*!re$ely !hank#ul !o all who have dire!ly or indire!ly
helped $e #or !he o$ple!ion o# $y work.
&hwe!a &a*ena
(./01%&/.M)/2)
VI
ORGAN*+AT*ON O, D*SSERTAT*ON
)he repor! 3Classifi!ation of Wis!onsin Dia"nosti! an& Pro"nosti! Dataset usin"
Pol$no'ial Neural Net-or). has +een divided in!o 2 hap!ers as #ollows4
C#apter / *ntro&u!tion
%hap!er / #irs! desri+es !he $o!iva!ion o# !his researh work. I! !hen desri+es +reas!
aner disease, i!s sy$p!o$s and !ypes in de!ail. )he hap!er also desri+es diagnosis
and prognosis proess o# !he disease.
C#apter / Literature Revie-
Di##eren! 5eural ne!work !ehni,ues #or diagnosis and prognosis o# +reas! aner
diagnosis and prognosis are desri+ed in !his hap!er along wi!h !he rela!ed work
onerned wi!h !hese !ehni,ues. )he hap!er also o$pares !he auraies o#
di##eren! !ehni,ues a! !he end.
C#apter 0 Artifi!ial Neural Net-or) an& Prin!ipal Co'ponent
Anal$sis
In !his hap!er 6r!i#iial 5eural ne!work is desri+ed in de!ail along wi!h i!s
advan!ages and $edial applia!ions. )he hap!er desri+es in de!ail !he higher order
or polyno$ial neural ne!work along wi!h +ak propaga!ion algori!h$ whih are used
in !his researh #or lassi#ia!ion. )he hap!er ne*! provides !he de!ailed in#or$a!ion
a+ou! da!a preproessing !ehni,ue na$ed Prinipal %o$ponen! 6nalysis and i!s
advan!ages.
C#apter 1 MATLAB
)he !ehnology used #or i$ple$en!a!ion o# proposed work is M6)-6B. )he hap!er
gives a +rie# in!rodu!ion o# M6)-6B along wi!h i!s advan!ages and de!ailed
desrip!ion o# 5eural 5e!work )ool+o* availa+le in M6)-6B #or design o# neural
ne!work. )he hap!er also e*plains !he neural ne!work design proess using neural
ne!work !ool+o*.
VII
C#apter 2
%hap!er 7 presen!s !he desrip!ion o# da!ase! used #or i$ple$en!a!ion o# !his researh
and !he resul!s o# i$ple$en!a!ion.
C#apter 3
%hap!er 1 onludes !he disser!a!ion and provides possi+le dire!ions #or relevan!
#u!ure work.
VIII
ABSTRACT
Breas! aner is !he $os! o$$on #or$ o# aner and $ajor ause o# dea!h in
wo$en. 5or$ally, !he ells o# !he +reas! divide in a regula!ed $anner. I# ells keep
on dividing when new ells are no! needed, a $ass o# !issue #or$s. )his $ass is
alled a !u$or. )his !u$or an +e anerous or non8anerous. )he goal o# diagnosis
is !o dis!inguish +e!ween anerous and non8anerous ells. (ne a pa!ien! is
diagnosed wi!h +reas! aner, !he prognosis gives !he an!iipa!ed long8!er$ +ehavior
o# !he ail$en!. Breas! aner de!e!ion, lassi#ia!ion, soring and grading o#
his!opa!hologial i$ages is !he s!andard linial pra!ie #or !he diagnosis and
prognosis o# +reas! aner. In a large hospi!al, a pa!hologis! !ypially handles a
nu$+er o# aner de!e!ion ases per day. I! is, !here#ore, a very di##iul! and !i$e8
onsu$ing !ask. (wing !o !heir wide range o# applia+ili!y and !heir a+ili!y !o learn
o$ple* and non linear rela!ionships inluding noisy or less preise in#or$a!ion
6r!i#iial 5eural 5e!works (655s) are very well sui!ed !o solve pro+le$s in
+io$edial engineering. 655s an +e applied !o $ediine in #our +asi #ields4
$odeling, +ioele!ri signal proessing, diagnosing and prognos!is. )here are
several sys!e$s availa+le #or !he diagnosis and sele!ion o# !herapeu!i s!ra!egies in
+reas! aner.
In !his researh we propose neural ne!work +ased linial suppor! sys!e$ !o provide
$edial da!a analysis #or diagnosis and prognosis o# +reas! aner. )he sys!e$
lassi#ies !he +reas! aner diagnos!i da!a whih are provided as inpu! !o neural
ne!work in!o !wo se!s8 +enign (non8 anerous) and $alignan! (anerous) !o ge! !he
diagnos!i resul!s. 9or ge!!ing prognosis resul!s !he sys!e$ lassi#y !he prognos!i
da!a whih are given as inpu! !o neural ne!work in!o !wo lasses8 reurren! and non8
reurren!. Resul!s +elong !o reurren! se! shows !ha! aner is reourred a#!er so$e
!i$e. Polyno$ial neural ne!work (P55) s!ru!ure is used along wi!h +ak
propaga!ion algori!h$ #or lassi#ia!ion o# +reas! aner da!a. :isonsin Breas!
%aner (:B%) da!ase!s #ro$ !he ;%I Mahine -earning reposi!ory is used as inpu!
da!ase!s !o P55. Da!a pre8proessing !ehni,ue na$ed Prinipal %o$ponen!
6nalysis (P%6) is used as a #ea!ures redu!ion !rans#or$a!ion $e!hod !o i$prove !he
auray o# P55. In our resul!s !he Mean &,uare error (M&') is su+s!an!ially
redued #or P%6 preproessed da!a as o$pared !o nor$ali<ed da!a. "ene we ge!
$ore aura!e diagnosis and prognosis resul!s.
Ke$-or&s8 4reast !an!er pol$no'ial neural net-or) prin!ipal !o'ponent
anal$sis -is!onsin 4reast !an!er &ataset.
I=