Bangladesh, Ethiopia, Kyrgyzstan, Thailand, and the Indian state of Tamil Nadu have all achieved substantial improvements in health or access to services. Good governance and political commitment, effective bureaucracies, and the ability to innovate and adapt to resource limitations were important.
Bangladesh, Ethiopia, Kyrgyzstan, Thailand, and the Indian state of Tamil Nadu have all achieved substantial improvements in health or access to services. Good governance and political commitment, effective bureaucracies, and the ability to innovate and adapt to resource limitations were important.
Bangladesh, Ethiopia, Kyrgyzstan, Thailand, and the Indian state of Tamil Nadu have all achieved substantial improvements in health or access to services. Good governance and political commitment, effective bureaucracies, and the ability to innovate and adapt to resource limitations were important.
Good Health at Low Cost 25 years on: lessons for the future of health systems strengthening Dina Balabanova, Anne Mills, Lesong Conteh, Baktygul Akkazieva, Hailom Banteyerga, Umakant Dash, Lucy Gilson, Andrew Harmer, Ainura Ibraimova, Ziaul Islam, Aklilu Kidanu, Tracey P Koehlmoos, Supon Limwattananon, V R Muraleedharan, Gulgun Murzalieva, Benjamin Palafox, Warisa Panichkriangkrai, Walaiporn Patcharanarumol, Loveday Penn-Kekana, Timothy Powell-Jackson, Viroj Tangcharoensathien, Martin McKee In 1985, the Rockefeller Foundation published Good health at low cost to discuss why some countries or regions achieve better health and social outcomes than do others at a similar level of income and to show the role of political will and socially progressive policies. 25 years on, the Good Health at Low Cost project revisited these places but looked anew at Bangladesh, Ethiopia, Kyrgyzstan, Thailand, and the Indian state of Tamil Nadu, which have all either achieved substantial improvements in health or access to services or implemented innovative health policies relative to their neighbours. A series of comparative case studies (200911) looked at how and why each region accomplished these changes. Attributes of success included good governance and political commitment, eective bureaucracies that preserve institutional memory and can learn from experience, and the ability to innovate and adapt to resource limitations. Furthermore, the capacity to respond to population needs and build resilience into health systems in the face of political unrest, economic crises, and natural disasters was important. Transport infrastructure, female empowerment, and education also played a part. Health systems are complex and no simple recipe exists for success. Yet in the countries and regions studied, progress has been assisted by institutional stability, with continuity of reforms despite political and economic turmoil, learning lessons from experience, seizing windows of opportunity, and ensuring sensitivity to context. These experiences show that improvements in health can still be achieved in countries with relatively few resources, though strategic investment is necessary to address new challenges such as complex chronic diseases and growing population expectations. Introduction Why do some countries achieve better health outcomes than do others at similar levels of income? In 1985, the Rockefeller Foundation convened a meeting in Bellagio, Italy, to consider the experiences of four countries or regions seen as success stories: China, Costa Rica, Sri Lanka, and the state of Kerala in India. All had achieved substantially better health outcomes than other nations at similar levels of development. The result was a publication entitled Good health at low cost 1 that not only dispelled the then widely believed myth that economic growth was necessary for health improvement but also identied specic factors associated with success. These were a commitment to equity, eective governance systems, and contextually appropriate programmes addressing the wider determinants of health. Politics also mattered, and every country or region was run by left- wing governments of various hues. 25 years later, the threats to health and the scope to respond are much more complex. Do the lessons of 25 years ago still apply? In 2011, we revisited the original countries and regions and looked at ve dierent places that were judged to have succeeded in either achieving long-term improvements in health and access to services or implementing innovative reforms relative to their neighbours (table). 2 We used a conceptual framework (gure) to assess how access to health care and good health are aected by context (global and national), sector (public and private), and systems (health and non-health). The nature of the success varies; some have achieved substantial health gains whereas others have improved coverage or health system performance but are yet to see the full eect. Here, we review the experiences of Bangladesh (panel 1), Ethiopia (panel 2), Kyrgyzstan (panel 3), the Indian state of Tamil Nadu (panel 4), and Thailand (panel 5) and reect on lessons they oer to other countries of low and middle income that are attempting to strengthen health systems in constrained or uncertain circumstances. In 200911, we undertook a series of historical case studies to investigate how and why these ve countries or regions made progress in health and access to care (panel 6). Our conceptual framework (gure) was based on existing published work 65,8082 and was used to identify a compre hensive range of factors related to health Lancet 2013; 381: 211833 Published Online April 8, 2013 http://dx.doi.org/10.1016/ S0140-6736(12)62000-5 Department of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK (D Balabanova PhD, A Mills PhD, L Gilson PhD, B Palafox MSc, L Penn-Kekana MA, T Powell-Jackson PhD, M McKee MD); Centre for Health Policy and School of Public Health, Imperial College London, London, UK (L Conteh PhD); USAID Quality Health Care Project, Bishkek, Kyrgyzstan (B Akkazieva MSc, A Ibraimova PhD); College of Humanities, Language Studies, Communication, and Journalism, Addis Ababa University, Addis Ababa, Ethiopia (H Banteyerga PhD); Department of Humanities and Social Sciences, Indian Institute of Technology (Madras), Chennai, India (U Dash PhD, V R Muraleedharan PhD); Health Economics Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa (L Gilson); Global Public Health Unit, School of Social and Political Science, University of Edinburgh, Edinburgh, UK (A Harmer PhD); Centre for Equity and Health Systems, icddrb, Mohakhali, Dhaka, Bangladesh (Z Islam MSc, T P Koehlmoos PhD); Miz-Hasab Research Center, Addis Ababa, Ethiopia (A Kidanu PhD, H Banteyerga); International Health Policy Program (IHPP), Ministry of Public Health, Nonthaburi Province, Thailand (S Limwattananon PhD, W Panichkriangkrai MPH, W Patcharanarumol PhD, V Tangcharoensathien PhD); Khon Kaen University, Khon Kaen, Thailand (S Limwattananon); and Health Policy Analysis Center, Bishkek, Kyrgyzstan (G Murzalieva PhD) Figure: Conceptual framework used for research Reprinted from reference 2, with permission of the London School of Hygiene and Tropical Medicine. Private sector Health system Non-health sectors Public sector Access to health care Good health .............. National context _. Global context Health Policy www.thelancet.com Vol 381 June 15, 2013 2119 systems, public provisioning (including social pro- grammes such as literacy and female empower ment), and politics and values underpinning the public process. This framework included a mix of quantitative and qualitative methods. 83 Findings were validated within and across countries. Our central study question was what determines achievement? Although the complexity of health systems, and the broader political systems in which they are embedded, means that no blueprint is available for producing a strong health system, 75,77 our Bangladesh Ethiopia Kyrgyzstan Tamil Nadu Thailand Economy GDP per person (PPP constant 2005, Int$), 2010 1488 3 934 3 2039 3 3522 4 7673 3 Demographics Population (millions), 2010 1487 5 830 5 53 5 721 6 (2011) 691 5 Infant mortality (per 1000 livebirths), 2009 41 7 67 7 32 7 27 8 (2011) 12 7 Under-5 mortality (per 1000), 2009 52 7 104 7 37 7 33 9 (2011) 13 7 Maternal mortality (per 100 000 livebirths), 2008 194 (2010) 10 470 7 81 7 97 11 (200709) 48 7 Life expectancy at birth (years), 2009 64 (male), 66 (female) 7 53 (male), 56 (female) 7 63 (male), 70 (female) 7 68 (male), 71 (female) 12
(estimate 200610) 66 (male), 74 (female) 7 Adult HIV prevalence (% aged 1549 years), 2009 <01% 7 1428% 13 03% 7 044% 14 (2007) 13% 7 Health system capacity Density of doctors, nurses, and midwives (per 10 000), 200010 6 7 3 7 80 7 12 15 (2008) 18 7 Hospital beds (per 10 000 population), 200009 4 7 2 7 51 7 10 16 22 7 Health system nancing Health expenditure, total (% of GDP), 2009 34% 17 43% 17 68% 17 40% 18
(estimate 200405) 42% 17 Health expenditure per person (current US$), 2009 1880 17 1470 17 5710 17 2790 18
(estimate 200405, US$1=Rs45) 16770 17 Health expenditure per person (constant 2005 Int$), 2009 4850 17 3990 17 15170 17 34470 17 Health expenditure, general government (% of total health expenditure), 2009 329% 17 476% 17 509% 17 177% 18
(estimate 200405) 759% 17 Out-of-pocket health expenditure (% of total health expenditure), 2009 648% 17 420% 17 399% 17 820% 18
(estimate 200405) 165% 17 Out-of-pocket health expenditure (% of private health expenditure), 2009 965% 17 801% 17 813% 17 100% 18
(estimate 200405) 681% 17 Private insurance expenditure on health (% of total health expenditure), 2009 02% 17 08% 17 .. 02% 18
(all India, 200405) 59% 17 Formal population coverage (% covered by insurance or tax-based arrangements), 2007 04% 19 100% 20 (depth of coverage varies, 2010) 100% 21
(nominal gure, 200506) 977% 19 Health-care coverage, most recent year available Births with skilled birth attendant 18% 22 (2007) 10% 23 (2011) 98% 24 (2006) 91% 25 (200506) 97% 26 (200506) Children (aged 1224 months) vaccinated with three doses of combined diphtheria, pertussis, tetanus 91% 22 (2007) 37% 23 (2011) 95% 7
(1-year-olds in 2009) 96% 25 (200506) 94% 26 (200506) Children (aged 1224 months) vaccinated with measles 83% 22 (2007) 56% 23 (2011) 99% 7
(1-year-olds in 2009) 93% 25 (200506) 96% 26 (200506) Currently married (or in union) women using modern contraceptives 48% 22 (2007) 27% 23 (2011) 46% 24 (2006) 60% 25 (200506) 70% 26 (200506) Children under-5 with suspected pneumonia taken to health provider 37% 22 (2007) 27% 23 (2011) 62% 24 (2006) 75% 25 (200506) 84% 26 (200506) Children under-5 with diarrhoea receiving appropriate treatment (oral rehydration therapy or increased uids, and continued feeding) 68% 22 (2007) 31% 23 (2011; among those who received any oral rehydration therapy) 22% 24 (2006) 47% 27 (200506) 46% 26 (200506) Estimates are based on the most current data available; where possible, indicators have been drawn from a common source to allow comparability across countries. As such, some gures might dier from those reported in Good health at low cost 25 years on, 2 which were the most current data at the time of publication. Furthermore, infant and under-5 mortality values were drawn from those estimated by the UN Interagency Group for Child Mortality Estimation, as reported in World Health Statistics 2011. 7 These estimates are based on tting mortality rate trend lines using all available data for every region, which is added to as new surveys are done over time. As such, every successive round of estimates could dier from and not be comparable with previous sets of estimates and the most recent underlying country data. GDP=gross domestic product. PPP=purchasing power parity. Table: Economic, demographic, and health systems data for the ve regions Correspondence to: Dr Dina Balabanova, Department of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London WC1H 9SH, UK dina.balabanova@lshtm.ac.uk Health Policy 2120 www.thelancet.com Vol 381 June 15, 2013 approach meant we could identify common patterns plausibly linked to better health and health care of potential relevance beyond the countries studied. 77 We describe here the main emerging themes focused on the health systems, with reference to topics related to other sectors and the wider context (panel 7). Characteristics of well functioning health systems Four characteristics linked to improvements in health and health care emerged from our analysis. The rst was good governance and political commitment; the second was eective bureaucracies and institutions; the third factor was the ability to innovate, especially with respect to service delivery; and the nal point was health system resilience (panel 8). Good governance and political commitment Governance underlies all health system functions 80 in addition to broader social development, 93 although the meaning of governance in relation to health systems is diverse and contested. 94,95 It includes the regulatory and managerial arrangements through which the health system operates, including how overall goals are set and monitored and how various components of the health system interact to achieve these goals. Governance also includes normative values (equity, transparency) and political systems within which health systems function. It links closely to the idea of stewardship, which was popularised by the 2000 World Health Report 96 that informed our approach. Stewardship implies a role of government to create a vision, formulate evidence-based policies, design responsive services, and monitor results. 94,97
Increasingly, alliances have to be built around shared goals in more pluralistic health systems. 80 Governance is also linked to political will, identied in the 1985 Good health at low cost report 1 as crucial to promote change, particularly in unfavourable economic circumstances. We identied several elements of good governance. Eective leadership was manifest in a clear political vision enshrined in a plan. In Ethiopia, leadership came from the prime minister Meles Zenawi (19912012) and the health minister Tewdros Adhanom (200512), although within a strongly decentralised system. In Tamil Nadu and Bangladesh, district level leadership was important for adaption of strategies to local conditions. Political leadership need not reside entirely in government: the Thai royal family have had a key role, promoting annual public health conferences and galvanising public support for reform. Indeed, we identied several inspirational leaders and key political workers committed to improve- ment of health in our study countries. Leadership seemed especially important to overcome the potentially damaging results of political upheaval. Clear priorities and realistic policy goals also emerged as important. Kyrgyzstans priorities were laid out clearly in its ambitious Manas plan (19962006), endorsed soon after independence, and subsequently the Manas Taalmi Panel 1: Health transcends poverty in Bangladesh In 1971, the Government of the newly independent Peoples Republic of Bangladesh was recovering from a devastating war of liberation in which about 3 million people died and much of the countrys infrastructure was destroyed. Worse, the country had high rates of mortality, low female literacy, and vulnerability to natural disasters, particularly ooding and famine. 28,29 Despite this di cult start, Bangladesh has made enormous health advances and now has the longest life expectancy, the lowest total fertility rate, and the lowest infant and under-5 mortality rates in south Asia, despite spending less on health care than several neighbouring countries. 30,31 The speed of change is striking: under-5 mortality has fallen from 202 per 1000 livebirths in 1979 to 65 per 1000 livebirths in 2006. 22 Comparable falls have been reported for maternal mortality. 10,32 Contributory factors include pronounced expansion of health-care coverage, with 75% of children younger than 1 year now fully immunised, 33 and a striking decline in fertility. 34 As a result, Bangladesh is on track to achieve the health-related Millennium Development Goals. We identied several factors associated with Bangladeshs success. A high-level political commitment to health dates back to independence. This commitment has endured despite major political changes, including transition from military to civilian rule, and has been facilitated by institutional continuity of civil servants and by partnerships between government and the non-governmental sectoran extender of government exemplied by the Bangladesh rural advancement committee. Bangladesh has pursued four important health policies. First, in a population policy, family planning was made a priority. A separate directorate was created within the ministry of health and family welfare that secured sustained investment and developed innovative community-based interventions. 35
Second, in 1982, a drug policy established a list of mainly generic essential drugs, and the Gonoshasthaya Kendra (Bengali for peoples health centre) provided a model for small-scale integrated primary care. 36 In 1983, the government established an essential drugs company to produce and distribute drugs within the public sector. This investment in indigenous expertise has created a substantial private pharmaceutical industry. 34 By the 1990s, more than 80% of essential medicines were produced locally. The resulting price stability has ensured that essential medicines are aordable. In 1998, a sector-wide approach was introduced that meant the many projects of dierent donors could be coordinated under the umbrella of a consortium led by the World Bank while ensuring that government remained in the driving seat. The third policy of human resources innovation created cadres of health assistants and family-welfare assistants. Early recruits were male eldworkers who were engaged in vertical programmes against smallpox and malaria in the 1960s and early 1970s; later they were joined by female health assistants. They work mainly in rural areas, delivering immunisation, health education, and distribution of essential medicines and contraceptives. Family welfare assistants were introduced in 1976. These workers are married woman who visit other married women of reproductive age in their homes to oer advice on contraception and provide free family-planning supplies. They are supported by a rapidly expanding network of primary health centres and a strengthened supply system. Bangladesh also pursued progressive policies outside the health sector, including education and female empowerment. Strengthening of the transport infrastructure and widening of access to electronic media facilitated access to health facilities and information. Bangladeshs disaster preparedness, based on intersectoral planning, has also improved health system resilience. 37
Finally, Bangladesh has prioritised research and development. Innovations range from medical interventionssuch as widespread implementation of oral rehydration solution, zinc to treat diarrhoea, and integrated management of childhood illnessto organisational responses, such as novel models of service delivery. Health Policy www.thelancet.com Vol 381 June 15, 2013 2121 plan, which set the agenda for a comprehensive overhaul of the health system. This clear and coherent vision paved the way for the only sector-wide approach in central Asia and attracted considerable donor support. 98
This clarity of vision was unique among former Soviet republics; much wealthier Kazakhstan only began to formulate such a plan in 2011. 46 The Ethiopian Government led a coordinated programme including many development partners, with a focus on access to essential services in isolated areas, based on an innovative health extension programme. 99,100 We found evidence of good governance and respon- siveness to diverse population needs and expectations. Investment in district health systems that could reach rural, isolated, and marginalised populations was especially apparent in Thailand, Bangladesh, and Ethiopia, all of which faced major challenges because of their large size and diverse populations. Initiatives to increase access to primary care by underserved groups entailed more home visits (Bangladesh and Tamil Nadu), scaling up of the primary care workforce (Thailand), and community engagement (Tamil Nadu and Thailand). Thus, since the early 1960s, Thailands health plans have reected an explicit egalitarian ethos among leaders and a commitment to cover underserved rural populations through the expansion of health infrastructure and deployment of health workers, particularly in rural areas; this pledge was facilitated by economic growth and institutional stability. In Ethiopia, services were extended to rural areas through the health extension programme; in Bangladesh, the voluntary sector was encouraged to reach out to geographically or socially isolated groups unable to access mainstream services. In both Ethiopia and Thailand, political leaders came from, or had worked in, rural areas and ensured that reduction of inequalities between urban and rural areasin health care and other sectors remained on the political agenda for many years. 2 Continuity of reform was present, even with changes of government, in all study countries. Initial blueprints typically served as a basis for subsequent reforms and made monitoring of their implementation possible. In Kyrgyzstan, these reforms continued over 15 years and through two revolutions, thus, lessons could be learnt and eective interventions scaled up. In Tamil Nadu, remarkable advances in maternal and neonatal health (eg, by improvements to emergency obstetric care accessed by poor populations) have been attributed to a strong political commitment to health that has been unaected by political changes. Consolidation of nancial protection schemes in Thailand, leading ultimately to universal coverage in 2002, also survived many changes of government, as did the purposeful expansionworking closely with voluntary organisations of district-level maternal and child services and managerial capacity in Bangladesh. Careful sequencing emerges as an important factor, particularly when it allows scope for experimentation. Early progress can create momentum that overcomes opposition to later, more controversial, initiatives. 101,102
The rapid achievement of high immunisation coverage in Tamil Nadu paved the way for eective family planning Panel 2: Health is placed central to development in Ethiopia In the 1980s, images on live television of children dying in Ethiopia, which were transmitted across the world over satellite links, brought home to those in rich countries the scale of a tragedy unfolding. The transitional government that came to power in 1991 inherited one of the poorest and least developed countries in Africa that, on top of all of its other problems, was just emerging from a bitter civil war. 38 20 years later, the transformation of Ethiopia is remarkable. Although still very poor, the country has achieved sustained economic growth. It has overcome the tensions that resulted from its status as one of Africas ethnically most diverse countries by means of a federal constitution that balances regional autonomy and a national vision. Under-5 mortality has fallen rapidly, overtaking several east African neighbours such as Sudan, Tanzania, and Uganda. 3 Deaths from malaria fell by more than 50% between 200104 and 2007, a decline associated with a tenfold increase in use of insecticide-treated mosquito netsnow among the highest level of use in the region (33%). 3 Between 2004 and 2008, the percentage of births attended by a skilled attendant doubled, although this proportion is still less than 10% of all births. 23 Immunisation rates have also increased greatly. 39 These gains are attributable in large part to an innovative approach to create a health workforce. 40 Faced with very few trained health professionals, in 2003 the Ethiopian Government launched a health extension programme, which was managed by district governments. Women with at least 10 years of education were recruited from local communities and given basic training in how to tackle common diseases. The programme is now seeking to improve retention and career progression and to cover nomadic populations in which very few women have even basic education and with complications for the supply chain. 40,41 As part of the health extension programme, new medical schools were opened and training of nurses and mid-level health o cers was scaled up. The mid-level o cers took responsibility for delivery of antiretroviral drugs and prevention of mother-to-child transmission of HIV. These initiatives have been backed up by regional and national investment in primary care infrastructure, essential drugs supplies, and management information. Progress is apparent in other sectors too. Primary school enrolment has reached 91% 3 and the prevalence of stunting fell by half between 2000 and 2005. 42 Access to clean water has also improved greatly. 39 The success in Ethiopia required peace and stability. The transitional government, although initially dominated by Tigrayans, built a multiethnic coalition, and the governing and major opposition coalitions are now dened in terms of ideology rather than ethnic origin. The multiethnic composition of the transitional government, coupled with a highly decentralised system of governance, has facilitated measures to redress historical inequities. It also needed leadership. The prime minister and health minister have been identied repeatedly by key informants from government and development partners in health as individuals committed to development, with the technical expertise and the political skills to communicate their vision. Successive sustainable development and poverty reduction programmes saw health as a contributor to and beneciary of development. 43,44 Investment was made in institutional strengthening. The pharmaceutical fund and supply agency is credited with reducing the time taken to procure drugs, from 360 days to 60 days. 45 Finally, Ethiopia has beneted from its geopolitical context, including its military intervention in Somalia. Western nations, particularly the USA and UK, have a strong stake in Ethiopias success, providing much development assistance. Without this funding, how Ethiopia could have achieved what it has is di cult to see. However, as the experience of other countries in Africa shows, development assistance can make little dierence without visionary individuals and eective institutions. Health Policy 2122 www.thelancet.com Vol 381 June 15, 2013 programmes as maternal and child health rose on the political agenda. Coherence among reform elements is seen as a reason why Kyrgyzstan is one of the most successful reformers among former Soviet republics, despite di cult economic conditions. 103 A commitment to evaluate changes created feedback loops to inform further reform. Successful leaders took advantage of windows of opportunity, although this approach needed support from institutions that could implement change. In 1972, leaders drafting a new Bangladeshi constitution inserted a legal right to health and created an environment open to voluntary and donor-led initiatives that complemented state programmes. In Ethiopia, the government that came to power in 1994 established a new health policy that was attractive to external donors. The Kyrgyz Government seized the opportunity to rebuild the collapsing health system after independence, creating a receptive environment for international support. Thai public health reformers took advantage of a populist political party to get universal coverage into their election manifesto, and they supported policy design and implementation after electoral success. Greater accountability safeguards scarce resources and boosts trust in health systems, ultimately aecting how people perceive and access them. This assurance includes measures to make nancing ows more e cient and transparent, thus tackling corruption and misuse of resources. The Tamil Nadu Medical Services Corporation provided an innovative model for increasing access to essential drugs but, crucially, reducing leakage. Similarly, in Thailand, the intersectoral 2004 programme about good governance for medicines 104 reduced ine ciencies in procurement and prescription of pharmaceuticals, achieving lower costs. It engaged voluntary organisations, such as the Rural Doctors Society, in raising awareness about corruption and unethical practices. Kyrgyzstan has undertaken a major investment in strengthening accountability and transparency, both in allocation of resources within the health system and tackling informal payments at facility level. Eective bureaucracies and institutions Development of sound policies and plans does not guarantee their eective implementation. In our study, functioning bureaucracies and institutions were deemed important for successful reforms. These organisations could be within the health sector (eg, ministries of health, district and subdistrict health institutions, or donor agencies) or outside it but whose operation inuences the functioning of health systems (eg, other ministries, the media, or development non-governmental organ- isations [NGOs]). We identied several important char- acteris tics of eective institutions: strong regulatory and managerial capacity; the ability to provide information and evidence; a stable bureaucracy; su cient autonomy and exibility to manage health systems eectively; willing ness to engage with several stakeholders, includ- ing non-state actors and local communities; synergy between governments and donors acting together to formulate and implement policy; and use of the media as a catalyst for change. Panel 3: Kyrgyzstan is a regional leader in health system reform The Kyrgyz Republic was one of the poorest of the 15 Soviet republics; its situation deteriorated even further after independence in 1991. Kyrgyzstan is mountainous, with less than 10% of land suitable for agriculture, and internal communications are often di cult. It has seen two revolutions since independence, the second associated with considerable bloodshed. 20 Yet, despite these problems, Kyrgyzstan stands alone in central Asia as an example of successful health system reform. 46 It has implemented a functioning health insurance system and has succeeded in shifting care out of hospitals and into a strengthened system of primary care, achieving nearly universal access. 47 Corresponding improvements have been noted in health outcomes. Infant mortality fell by almost 50% between 1997 and 2006, with similar declines in under-5 mortality. 24
Life expectancy exceeds that of several of the more prosperous former Soviet republics, including Russia. 48 Fertility has fallen by almost 50% since the 1970s, skilled birth attendants are present at 98% of deliveries, and immunisation rates exceed 90%. 49 The reform process began soon after independence. The scale of the crisis made radical reform imperative. Kyrgyzstan turned to the outside world for assistance, recognising that the old system was unsustainable. The rst of a series of health reform programmes was launched in 1996; it was promoted as an example of how government reforms would benet the people, thus linking its success to that of the government. 50 One of the main goals of the health reform programmes was to restore universal health coverage. A mandatory single payer health insurance fund was created, expanding as resources have allowed and now covering more than 80% of the population. This fund is complemented by a state-guaranteed benets package for vulnerable populations; an additional drugs package subsidises essential medicines. A prospective case-based system for inpatient care and a capitation-based scheme for primary care have been implemented. Endemic informal payments have been reduced substantially. 51 The inherited health system was dominated by the hospital and had an abundance of sta, but few of these health workers had the necessary skills to practise modern medicine and basic equipment and drugs were scarce. This system has now been downsized, with 42% of hospitals closed between 2000 and 2003. 52 Community health centres were upgraded to compensate for these closures. Almost all primary care doctors were retrained as family practitioners, supported by nurses and midwives and better-trained mid-level health workers, including Soviet-era feldshers (auxiliaries). 53 Coverage gaps in isolated mountain areas were addressed by village health committees, with volunteers contributing to basic preventive and treatment interventions. We identied several factors associated with Kyrgyzstans achievements. The rst was the need for reform. The inherited health system faced collapse and action was needed to maintain the legitimacy of the regime. The second was leadership. The countrys rst president, Askar Akayev, identied health-care reform as a priority and gave it considerable support while opening Kyrgyzstan up to the international community, by contrast with the situation in other former Soviet republics. This move also paved the way for signicant development assistance. The third factor was a functioning legislative system. Laws have survived two revolutions. They include not only those underpinning the comprehensive health reforms but also those guaranteeing the independence of civil servants, ensuring continuity of programmes (seen in the successive Manas health programmes) and sta at times of political change. Furthermore, investment in research was provided, with skilled expatriate advisers contributing substantially to capacity within the health ministry. Health Policy www.thelancet.com Vol 381 June 15, 2013 2123 Strong regulatory and managerial capacity were judged important, particularly where resources were scarcest. In Kyrgyzstan, a functioning legislative processenabling passage of three major laws enacting changes in the health system over 4 yearsaccelerated the move towards compulsory health insurance and universal coverage. In Tamil Nadu, we doubt whether many innovations would have been successful without the states unique public health management cadre at district level, with power to plan and manage services. 105 In Bangladesh, a district management group, with delegated authority, imple- mented government programmes and supervised con- tracts with diverse NGOs and private providers. Managers were supported by provision of intelligence and evidence to evaluate outcomes of reforms, including widespread use of pilot schemes in Kyrgyzstan and Thailand. Tamil Nadu developed a system of mandatory surveillance and audit of maternal deaths covering both public and private sectors. 106 This move enabled identication of systemic weaknesses, and district o cers were empowered to develop locally appropriate solutions. Those ideas that proved eective were replicated in other districts, feeding into evidence-based protocols at state level. 107 Both Kyrgyzstan and Thailand created research institutes associated with their health ministries, to support transfer of knowledge into policy. Panel 4: Tamil Nadu is a success story in India Of Indias 28 states, Tamil Nadu is the seventh most populous. Despite spending only about 1% of its gross domestic product on health, this region has made great progress in improving population health. Between 1980 and 2005, infant mortality fell in Tamil Nadu by 60%, compared with 45% for India as a whole, 8 with the greatest gains in rural areas. In 2006, this state had the third lowest rate of under-5 mortality in India, at 355 deaths per 1000 livebirths, compared with 743 deaths per 1000 livebirths for India as a whole. 25 However, the greatest achievement in Tamil Nadu has been reduction of maternal mortality, from 319 deaths per 100 000 livebirths in the early 1980s to 111 deaths per 100 000 livebirths in 200406, the second lowest of any Indian state. 54 This decline was much faster than in India overall. By 2006, fertility was below replacement rate. 8 A characteristic of Tamil Nadus success is the high health-care coverage: 90% of deliveries are attended by a skilled birth attendant, 25 almost 25% of deliveries take place in primary health-care facilities, 55 and 81% of infants are fully immunised. 25
Four health system-related factors underpin these achievements. First, Tamil Nadu was one of the rst states in India to implement in large scale a multipurpose worker scheme in 1980. Women with at least 10 years of schooling were trained for 18 months to become village health nurses. Existing maternity assistants were retrained and new training facilities were built. Second, an initiative was proposed by the Indian Government to build a network of primary health-care centres; Tamil Nadu was one of the rst states to build a vast network of these facilities. By 2005, about 1500 primary health centres were open in the state, every one serving about 30 000 people on average, and a further 8680 subcentres were availableone of the highest levels of coverage of any Indian state. Innovative approaches to funding and construction were used in Tamil Nadu, including volunteer labour from communities. Obviously, to build health facilities is not enough, they must also be open and responsive to needs. 24-h opening began in the mid-1990s and is now the norm, with performance monitored monthly. 56
Third, immunisation schedules were scaled up rapidly, assisted by UNICEF, the Rotary Club, and the Christian Medical College in Vellore. By the early 1990s, Tamil Nadu had achieved the highest immunisation coverage in India, with the narrowest gap between the richest and poorest quintiles and between rural and urban areas. Integration of immunisation within primary care had assisted this achievement. 57 Finally, a reliable supply of essential drugs was established in Tamil Nadu. The autonomous Tamil Nadu Medical Services Corporation was created by the Indian Government in 1995 to purchase and distribute pharmaceuticals to public health facilities. It replaced the former drug procurement and distribution system, which had faced persistent di culties including misuse of funds, inappropriate prescribing, high distribution costs, and stock outs. The new system, providing about 250 generic essential drugs, is credited with substantial improvements in drug supply and transparency. It has also contributed somewhat to driving down the cost of drugs supplied in the private sector. 58,59 Outside the health sector, important successes in Tamil Nadu have included female empowerment and investment in infrastructure, in particular electricity and clean water. 6062 The achievements seen in Tamil Nadu were made possible in several ways. First, a strong commitment to health was made by successive state governments, which persisted despite frequent changes to the party in power. Second, successive health secretaries drove forward innovation and were supported by civil servants with both technical expertise and power to implement wide-ranging reforms. Sometimes, quasi-governmental organisations had to be created, such as the Tamil Nadu Medical Services Corporation, which could circumvent tardy bureaucratic processes. 58 Third, investment in managers trained in technical public health skills and management at district level was sustained over many years, a unique cadre in India. A system of career progression has allowed Tamil Nadu to attract and retain high-calibre sta. 63
Fourth, the partnership between government and non-governmental organisations was important, especially in the management of AIDS and tuberculosis. Health Policy 2124 www.thelancet.com Vol 381 June 15, 2013 In Kyrgyzstan, monitoring and evaluation became an integral part of the policy cycle. Stability of bureaucracy over time was regarded as important to sustain the momentum of reforms, facilitating retention of institutional memory and values. Despite great political and economic turmoil in some of the study countries, managers and planners pursued reform strategies long enough to show results. Thailands bureaucracy has proven especially resilient to changes of government. Containing many senior o cials with substantial rural work experience, the ministry of public health was able to maintain reforms through successive 5-year health plans. Despite two revolutions, Kyrgyzstans health reforms remained on course (by contrast with the experiences of neighbouring countries that were politically more stable), helped by the deliberate policy of creating and retaining a cadre of managers and planners and reducing political inuence over appointments. While ensuring stability, bureaucracies also needed su cient autonomy and exibility to manage health systems eectively. The autonomous Tamil Nadu Medical Services Corporation was able to bypass bureaucratic procedures to introduce a system of drug procurement, increasing availability of essential drugs. Every one of our study countries leaders showed a willingness to engage with several stakeholders, including non-state actors and local communities. For example, Kyrgyzstan established village health com mittees staed by volunteers to deal with a wide range of local issues, including public health, and this move facilitated access to care and health education. In Thailand, district health authorities were encouraged to establish publicprivate partnerships that attracted resources and expertise while remaining free from political interference; these links were supported by senior ministers and the royal family. 108
Bangladesh has seen a major expansion of NGOs opera- ting in the health sector since independence in 1972. Some are now vast organisationsfor example, the Bangladesh rural advancement committee reaches up to 110 million people through 64 000 village health workers. These NGOs have made a major contribution to national goals, such as prevention of diarrhoeal deaths in children and provi sion of health services to marginalised popu- lations. Bangladeshi community-based organisations work ing in health and micronance have supported locally appro priate interventions, leading to striking improve ments in access to maternal and child care, 109 but they have been less successful at aecting policy at national level because of limited capacity and inuence and opaque formal consultative processes. 110 Involvement of more than one stakeholder is only part of the story, however. Also important was a willingness to look at a range of pragmatic solutions, such as exible models of publicprivate collaboration that take account of local context. These sought to build on complementary capacities in every sector, to expand Panel 5: Why and how did Thailand achieve good health at low cost? Thailand has made impressive health gains in the past 25 years. Infant mortality fell from 68 per 1000 livebirths in 1970 to about 10 deaths per 1000 livebirths in 2006. 64 This decline is one of the fastest seen out of 30 countries with low and middle income between 1990 and 2006. 65 Improvements in life expectancy have also been noted, although recent progress has been limited by the spread of AIDS. 66,67 The total fertility rate, which was 63 births per woman in 1965, had fallen below replacement by 1994. 68
After the Millennium Development Goals (MDGs) were met, Thailand adopted country-specic targets known as MDG Plus, which underpin its development policy. 69 The achievements seen in Thailand are associated with progressive expansion of health-care coverage. In 2001, the government unied a series of existing but fragmented systems to achieve near-universal health coverage even though, at the time, the region was aected by the Asian nancial crisis. Health-care utilisation increased and catastrophic expenditure and out-of-pocket payments fell substantially. 70 Reforms to delivery took place from the 1960s onwards as part of a series of 5-year national economic and social development plans. These measures established and sustained new hospitals. However, Thailand saw an exodus of doctors during the Vietnam War, with many Thai graduates moving to the USA. The government introduced a bonding system, requiring newly qualied doctors to spend 3 years in government health facilities, mostly in rural areas. This scheme was later extended to other health professionals. The situation was even more important for nurses, who were trained in insu cient numbers in universities under the ministry of education. As a result, in 1961, the ministry of public health established its own nursing and midwifery colleges. Furthermore, in 1982, a 2-year technical nurse diploma course was introduced in place of 4-year training. After 4 years of mandatory rural health service, technical nurses could undertake an additional 2 years of training to obtain a bachelors degree and professional qualication. These policies resulted in substantially augmented numbers of doctors and nurses serving in rural district health services. Health gains in Thailand also reect policies outside the health sector, in particular, sustained investment in rural development, encompassing infrastructure expansion and improvements in adult literacy, notably among women. Several factors were associated with these changes. First, high priority was given to health by successive governments, reected not only in statements by politicians but also in successive national plans. This step has transcended changes of government, both military and civilian. Thailand has had several charismatic health ministers, again under both military and civilian governments, many with a high level of technical expertise. They have championed the strengthening of rural health care and expanded coverage of maternal and child health services. However, other inuential leaders in academia, health-care delivery, and civil society have played a part. In interviews we undertook with former policy makers at the Ministry of Public Health, professionalism was reported as a consistent characteristic of these individuals, rather than nancial gain. Another key factor was the role of the Thai royal family and, in particular, the popular sense of duty in serving them. The Thai monarchy has provided a point of stability during political changes and has also had an active role in promotion of healthPrince Mahidol of Songkla, father of the present king, was trained in public health. Second, institutional capacity was important in Thailands success. Many senior sta have trained overseas and have beneted from stable employment in the public sector, ensuring continuity and institutional memory. Non-governmental organisations and professional bodies have also played a positive part, such as the Rose Garden group, an informal group closely linked to the Rural Doctor Society of Thailand, which provides a forum for policy debate and has helped tackle corruption. 71 Finally, the ability to translate health policies into practice has been facilitated by strong managerial capacity in provinces and districts, 72 coupled with extensive piloting and evaluation to ensure that policies take full account of the Thai context. 73,74 Health Policy www.thelancet.com Vol 381 June 15, 2013 2125 services responding to diverse needs. For example, in Tamil Nadu, the private sector undertakes 80% of outpatient visits and 60% of admissions, while preventive maternal and child health care continues to be provided in the public sector. Publicprivate engage- ment is common in contracting out clinical and laboratory services and information cam paigns. Allo- pathic and non-allopathic wards (Siddha) are located within the same public facilities, responding to user preferences. Many examples exist of synergy between governments and donors, acting together to formulate and implement policy and align eort, generally within sector-wide approaches (SWAps). Kyrgyzstan and Ethiopia, both beneting from much donor support as a result of geopolitical factors, achieved consensus among donors on key reform priorities and how to allocate resources. The 1998 Bangladesh SWAp brought together 120 separate health programmes, reducing frag men- tation and creating opportunity for scaling up. Ethiopia Panel 6: Research approach and methods In this study, we sought to examine why some countries are more successful than others in achieving better health or expanding access to essential services. The starting point was that health systems are complex 75,76 and entail the interplay of multiple interacting causes generating a set of often unpredictable eects. 77 For every country, we aimed to identify interventions that could be linked to specic health gains, which were mainly in the area of maternal and child health, a choice that reected availability of data. We then sought to understand how and why specic developments took place, covering factors within health systems and their broader context, with the aim to identify plausible pathways to health improvement based on an integrated analysis across levels of the health system in dierent settings. 77 We used historical methods to trace the development of policies and programmes over long periods. We incorporated theories of path dependency of institutional development 78
and of health systems resilience. 79 The countries we studied were selected from a list provided by the Rockefeller Foundation, which was based on preliminary analysis of good maternal and infant mortality outcomes relative to comparator countries with similar levels of total health spending. Further considerations were given to experience of innovative system-level reforms despite nancial constraints. Moreover, geographic, economic, and health system diversity were considered. The study design and data analysis protocol were explicitly comparative. Rigour was achieved with a common conceptual framework adapted to local settings to support comparisons (gure) and the methodological approach, and regular interaction took place among country research teams. The framework drew on existing health systems frameworks 8082
and encompassed both private and public sectors, recognising their relevant roles in dierent settings. The framework also allowed for non-health system factors that aect health (eg, policies to improve literacy, female empowerment). Health system and non-health system sectors were investigated within wider national and global contexts (eg, governance, economic and political factors, culture) that aect both the operation of national health systems and health achievements. 83
Case studies were undertaken from 2009 to 2011 and included a mix of quantitative and qualitative methods. 2 Secondary analyses or synthesis of statistical data relevant to health system performance. A scoping review of published work with an iterative search process based on the conceptual framework, using PubMed, Medline, BIDS, HINARI, EconLit, and Google Scholar and supplemented by media accounts. 84
Documentary review of relevant published and grey literature at country level, obtained through contacts with key informants and searches of local resources. In-depth interviews with current and former employees, who were key informants identied as especially knowledgeable on important policies and programmes, and people working across countries in the region, who were included to promote a comparative focus. Focus groups (in some countries). We asked several questions in every country. 1 Why is the country an example of good health at low cost? 2 What key areas of health improvement have secured good health at low cost over the last few decades? 3 How has the country achieved these specic health gains (what diseases or conditions have been tackled)? 4 How did the health system and other sectors support the eective delivery of these interventions? 5 How and why were these health system developments and wider policy interventions possible? 6 What other sociocultural and political factors may explain health gains? The framework analysis mirrored the conceptual framework and allowed for particular factors to emerge as dominant within every country. The process was iterative: as new themes and propositions emerged in one country, they were sought in the experiences of the other countries, and reasons for divergence were investigated. This information was then incorporated into data collection. At country level, ndings were validated by triangulation of several data sources, peer review, public debate with current and past health system actors, and review of ndings against relevant published work. We also obtained reviews by international experts on particular issues or countries. We prepared working papers, discussed them at team meetings, and undertook a peer-review procedure. Health Policy 2126 www.thelancet.com Vol 381 June 15, 2013 Panel 7: Contribution of non-health system factors to good health Distinguishing between health system and non-health system factors is not straightforward. For example, politics and economics are both integral to WHOs health systems framework: politics in the guise of leadership and governance, economics in terms of health nancing. Furthermore, to distinguish between the two sets of factors could be detrimental to successful health policy, because a so-called silo mentalityie, a reluctance by dierent development sectors to explore cross-sector or synergistic collaborationcould be encouraged among development agencies. To illustrate the health eects of non-health system factors, we discuss three factors that contributed to the good health outcomes reported in our country studies. Infrastructure Some evidence suggests that investment in national infrastructure has yielded health dividends. For example, rural electrication in Thailand has been linked to falling fertility. 85 In Bangladesh, improvements to road infrastructure have augmented access to emergency obstetric care and birth outcomes, despite persistent high levels of home-based and unattended deliveries. 86 The improved transport infrastructure and targeted subsidies (through a voucher scheme to reimburse transport costs) are believed to have contributed to better access to rural clinics. 2 Rapid expansion of communications technology enabled more people to access information on healtheg, in the multimedia Bangladeshi Behaviour Change Communication campaign. Empowerment Female empowerment and gender equity are recognised widely as key determinants of development. 87 Thus, we looked at gender issues in our ve countries or regions. None had consistently high results on the standard indicators of gender equality. For example, in 2008, Thailand ranked 69th on the United Nations Development Programs gender inequality index (Kyrzystan was 63rd and Bangladesh 116th). 88 Women in the ve countries or regions enjoy fairly high political proles. Kyrgyzstan elected the rst female president in central Asia and has made a considerable achievement in boosting the political representation of women in parliament, by comparison with its neighbours. Bangladesh has had a female prime minister and leader of the opposition for the past two decades and both the home and foreign ministers in the 2011 cabinets are women. Thailand appointed a female prime minister in 2011. Since 1991, a woman has been one of the two alternating chief ministers in Tamil Nadu. In Ethiopia, many women have held ministerial and other high government roles, in social aairs, nance, and labour. However, whether these appointments have really led to important shifts in attitudes towards, or improvements in, opportunities for women in Ethiopia is debatable. Our case study ndings suggest that progress towards empowerment of women and gender equality in Tamil Nadu, Ethiopia, Bangladesh, and Thailand owes more to civil society-led and community-based initiatives than to government activities. Policies in other sectors have helped to improve the position of women and their health outcomes. In Bangladesh for example, families who participated in microcredit programmes achieved better child survival. 89,90 Furthermore, strengthening of primary care in Tamil Nadu was accompanied by measures to increase female literacy and age at rst marriage. By contrast, in Soviet-era Kyrgyzstan, women had access to education and paid employment, but since independence throughout central Asia, some of these opportunities have been threatened by strengthened religion traditions. Education Since the 1970s, the mean years of education for adults aged 25 years or older in the ve countries or regions has risen. Between 1970 and 2009, respective increases for men and women were 23 and 20 years in Bangladesh, 18 and 07 years in Ethiopia, 58 and 65 years in Kyrgyzstan, and 30 and 38 years in Thailand. 91 The eects of expansion of education on child health have, however, been remarkable, averting 42 million deaths according to one estimate based on a survey of 175 countries. 91 The growth of female literacy in Thailand shows the importance of education as a pathway to better health. The proportion of literate women in Thailand has been high for at least a quarter of a century, rising from 97% in 1980 to 99% in 2002. An analysis undertaken for our study shows that, in 2006, the rate of enrolment into education was higher for females than males, particularly at the tertiary level. The benets of better education are clear: augmented employment opportunities and reduced under-5 mortality rates. 2 Kyrgyzstan has beneted from a model inherited from the era of Soviet rule, of near-universal education for men and women, which to a large extent has been sustained in the face of subsequent nancial shortages. A combination of factors contributed to increased adult female literacy in Bangladesh (from 18% in 1980 to 51% in 2008): government provision of free secondary schooling for girls; active civil society, particularly the Bangladesh rural advancement committees involvement in delivery of education; and microcredit. In Tamil Nadu, factors related to demand (eg, better education for women) and supply (eg, improved family planning services) have both been suggested to account for the states impressive reduction in fertility, which reached a replacement level of 21 by 199091. However, the conclusion of a 2002 study comparing fertility across several Indian states, including Tamil Nadu, was that there was no threshold level of female education or infant mortality that [could] be considered for augmentation of fertility decline. 92 Neither economic nor social development factors fully explained fertility transition in Tamil Nadu. The authors argued that community acceptance of (or demand for) certain practices associated with fertility decline (such as contraception or improved education services) had more of a part to play, rather than individual behaviour. Health Policy www.thelancet.com Vol 381 June 15, 2013 2127 attracted large quantities of development assistance and prioritised the improvement of donor harmonisation for its health sector, leading international eorts in this area through its support for the inter national health partnership. The media has sometimes served as a catalyst for change, disseminating public health messages, increas- ing awareness of entitlement to care, and tackling deeply rooted beliefs about health. In Tamil Nadu, media campaigns promoted AIDS awareness and family planning. In Thailand and Bangladesh, the media oered a means to hold authorities to account and raise local issues on the national agenda. Innovation All study countries showed innovation in various aspects of their health systems. Particular originality was seen in the workforce (which is a severe constraint in all countries), nancing mechanisms, and means of delivering services. Innovative health workforce strategies In the 1985 report Good health at low cost, 1 a link was made between investment in well trained health workers, particularly in primary health care 102 (eg, Chinese barefoot doctors), and better health. The new countries studied in the follow-up report 2 implemented a combination of established and innovative strategies to overcome sta and skill shortages at all levels. Task shifting and changes in skill mix were common themes. 111 In Thailand, expansion of human resources was judged a crucial step towards extension of coverage. In Kyrgyzstan, a new family medicine training centre led large-scale retraining of family doctors. Bangladesh made a major investment in emergency obstetric care in the public sector, with new facilities and sta trained and deployed to rural areas. The Ethiopian health extension programme (panel 2) is perhaps the most ambitious eort in sub-Saharan Africa to scale up the supply of primary workers and reduce the imbalance of health workers between rural and urban areas. These community-based sta brought essential primary care to almost two-thirds of the population by 2007, 112,113
contributing to higher immunisation rates, improved malaria prevention, and accessible maternal and child health care in remote areas. 114 In Tamil Nadu, the multipurpose workers scheme (village nurses), launched in the early 1980s, was scaled up rapidly. It now delivers integrated primary care in rural areas, with strengthened infrastructure and increased drug supply. Changes made in our study countries included skills enhancement and task shifting. For example, in Kyrgyzstan, general practitioners are replacing doctors trained under the Soviet system, 111 and in Ethiopia, health extension workers are delivering primary care that would once have been undertaken by nurses or doctors. Thailand introduced village health volunteers while enhancing the skills of public health nurses. Bangladesh took advantage of the many sta who had played a part in smallpox eradication and used them to form the core of a new cadre of health and family welfare assistants. Many of the existing community workers became village doctors (palli chikitsok) or unlicensed providers, particularly in rural areas. These people have been credited for some of the reduction in childhood mortality because they have enhanced access to basic medical advice and low-cost drugs. 115,116 In Tamil Nadu and Bangladesh, community health workers increased the scope of their activities, including primary care and referrals during home visits, which augmented the level of integration between vertical programmes, particularly in maternal and child health. Challenges persist everywhere with respect to recruitment and retention of health workers in rural areas. 117 Ethiopian health extension workers were recruited from local communities into the civil service, thus providing stable employment, training, and career progression. 2 In both Tamil Nadu and Thailand, posting of medical graduates to rural areas was seen as a stage in professional development. 2
Health system nancing and nancial protection While all ve study countries have shown a rise in real total expenditure per person on health since 1995, the rate of increase has varied. 17 The most pronounced Panel 8: Characteristics of well-functioning health systems Good governance and political commitment Eective leadership and long-term vision Clear priorities and realistic policy goals Responsiveness to diverse population needs Continuity of reform Careful sequencing of reforms Seizing windows of opportunity Enhanced accountability Eective bureaucracies and institutions Strong regulatory and managerial capacity Provision of intelligence and evidence Stability of bureaucracy Su cient autonomy and exibility to manage health systems eectively Engagement with many stakeholders, including non-state actors and local communities Synergy between governments and donors acting together to formulate and implement policy Use of the media as a catalyst for change Innovation Novel health workforce strategies New approaches to health system nancing and nancial protection Pragmatism in service delivery Resilience in the health system Health Policy 2128 www.thelancet.com Vol 381 June 15, 2013 growth in spending was in Thailand whereas Ethiopia showed the smallest increase, which seems surprising in view of the external support the country has accrued in recent times, suggesting substantial displacement of government spending. 118 The increases have paralleled general economic growth; total health expenditure as a percentage of the gross domestic product (GDP) has remained largely stable over the years. 17 Of the study countries only Kyrgyzstan has had any notable uctuation, with a sharp drop in total health expenditure as a percentage of GDP in the late 1990s, followed by nearly a decade of recovery to previous levels. As well as understanding total expenditure patterns, we also must know where funding comes from and goes to. In Thailand, the share of government health spending in total health expenditure has been rising over several years and more sharply since the implementation of universal coverage in 2001. With the emphasis on publicly funded health care, out-of-pocket payments in both Thailand and Ethiopia are relatively low, only 14% of total health expenditure in Thailand (2010) 119 and 42% in Ethiopia (2009), 17 which is low compared with India and Bangladesh, both of which have extensive private sectors. In Bangladesh, for example, there are three major suppliers of health care in the non-state sector: NGOs; formal and informal private sector providers; and suppliers of traditional medicines. The share of government and out-of-pocket payments has uctuated in Kyrgyzstan (with recent declines in out-of- pocket payments), 120 reecting the move to mandatory social insurance and the long-established formal and informal top-up paid by users. All study countries recognised that the nancial burden of seeking health care aects vulnerable households disproportionally, through unexpected and sometimes catastrophic out-of-pocket payments. 121,122 Ethiopia is developing a system of social health insurance for employees in the formal sector and community health insurance for others. Both Thailand and Kyrgyzstan have achieved almost universal cover age, but in Kyrgyzstan, some groups remain with out coverage and out-of-pocket (and informal) payments persist. The depth of coverage (benets package) is important as well as its breadth. Kyrgyzstan has gradually expanded the basic benets package with continued government support. In Thailand, renal replacement therapy was included explicitly to avert risk of catastrophic expenditure. Early adoption of anti- retroviral treatment was possible because the Thai Government pharma ceutical organisation produced low-cost, generic combination therapy. In Kyrgyzstan, the state guarantee benet package has been revised annually to reect available funds. However, this review has not happened in Bangladesh where, despite a rapid increase in non-communicable disease, the package remains unchanged. Another way to increase the resources available for health is to improve e ciency. Kyrgyzstan implemented a single-payer system for providers, linking resource allocation to performance. It was the only country in the former Soviet republic that radically downsized its inherited hospital infrastructure, redirecting funding to patients care. 103 Service delivery We identied many innovations in service delivery in our ve study countries or regions. For example, in Bangladesh, low-cost innovations were introduced to treat common illnesses, such as oral rehydration solution and zinc to treat diarrhoea, and these strategies were delivered by community workers. In Tamil Nadu, publicprivate partnerships were used to expand capacity. The Ethiopian health extension programme is another novel idea for service delivery. All countries reorientated services towards primary care, although with easier referral to higher tiers, thus reinforcing the message in the 1985 report Good health at low cost 1 and subsequent evidence about the important role of aordable community-based health care. 123 Since the 1970s, a gradual move has taken place from vertical models of care (eg, family planning in Bangladesh) towards integrated models prioritising maternal and child health services, although this transition has been more di cult in places with diverse providers (eg, Bangladesh and Tamil Nadu). Another key area of innovation that has supported eective service delivery is increased access to aordable medicines. Both Bangladesh and Tamil Nadu adopted predominantly public-sector solutions and contracted- out only some tasks, to promote aordability. In Ethiopia, greater access to drugs boosted the ability of health extension workers to deliver eective care. Implemen- tation of exible service provision models that reect the context, rather than transplanting models from else- where, has been instrumental in improving access and achieving substantial health gains. Building resilience in the health system Health systems are sometimes vulnerable to unexpected shocks, leading to growing interest in how to foster resilience. 79,124 Thailand and Ethiopia have recently been aected by large-scale natural disasters and have sub- sequently put in place systems to prepare for similar events in the future. Long experience with seasonal oods and cyclones has made Bangladesh a model of development for appropriate infrastructure and systems to coordinate emergency responses, such that recent natural disasters (eg, cyclone Sidr in 2007) have not led to the mass casualties seen in previous eras. Thailand has implemented early- warning systems for tsunami and implemented the 2010 Association of SouthEast Asian Nations (ASEAN) cooper- ation in ood prevention and rehabilitation. Ethiopia has enhanced its ability to respond to droughts, although capacity remains limited, as shown by the eects of the 2011 famine in east Africa. Health systems have been central to these preparations, creating spillover eects in Health Policy www.thelancet.com Vol 381 June 15, 2013 2129 terms of improved planning, strengthening of institutions, and streamlining of processes. Cross-cutting lessons Here, we have attempted to distil cross-cutting lessons from our analytical case studies of Tamil Nadu in India, Bangladesh, Kyrgyzstan, Thailand, and Ethiopia. Cross- country analysis of national or regional experience has value for identication of common themes, even if the detailed characteristics vary. Although we do not present a roadmap for success, our synthesis draws attention to health system and non-health system factors that seem to be important across our study countries for achievement of good health outcomes. Health system strengthening is much more than mechanistic implementation of a series of essential interventions, and formal policy fullment can be hampered by unintended outcomes. 75
We should be cautious when we interpret our conclusions because our study had several limitations. We could only analyse ve countries in detail, although within the study we did undertake a broader review of published work on health system performance to inform our methods. We focused on a specic set of countries judged to have had a fair amount of success in achieving health gains and improving coverage. To undertake in-depth research in countries with similar character istics, but that had not made comparable progress, was beyond the scope of our study. Major data gaps were seen in all countries (less so in Thailand), particularly for reliable longitudinal data at subnational level, and the scarcity of counterfactuals that could be used to investigate associations between health policies, cover age of inter ventions, and outcomes meant that we were only able to identify plausible associations rather than imply a causal attribution. Recognising these challenges, we aimed to strengthen rigour with analytical and methodo logical approaches, including a historical perspective (panel 6). We sought comparability through setting the experience of study countries in the context of their regions, where possible, and analysing similar experiences in dierent settings. 125
The phrase good health at low cost conveys the message that health improvements can be achieved in countries at relatively low income levels. The national and regional experiences show how progress in health and access to care has been possible even with limited resources. Coverage of essential interventions delivered in primary care settings has improved, with support from health-promoting policies in other sectors and without a substantial increase in the share of national resources spent on health. Although we acknowledge that sustained nancial investment in health systems is essential for further progress, the experiences we describe show what committed politicians, eective managers, motivated health workers, eective institu tions, and involved com- munities can do in constrained circumstances. We have highlighted the importance of individuals in creating ideas and generating political momentum. But community matters too, as the relation between education and fertility transition in Tamil Nadu shows. In all countries and regions, good governance and leadership were important for determining whether the health systems operated eectively. Our study reiterates many of the messages that emerged from the original Good health at low cost report, 1 and other well established evidence, about the need to orientate health systems towards primary care, backed up by eective referral systems, the importance of strategic action, supported by multiple stakeholders. The relevance of inclusive and community-orientated primary health care is restated elsewhere, 123,126 and the report of the Commission on Social Determinants of Health emphasises the need for intersectoral action to promote health. 127,128 Specic aspects of governance encompass leadership and vision by government and translation of this vision into action, including the ability to maintain continuity despite turmoil, to seize windows of opportunity, to be responsive to population needs, and to be committed to account- ability. Stable institutions and bureaucracies that have adequate regulatory and managerial capacity and institutional memory provide means to learn from experience. A degree of autonomy and exibility in the way a government operatesenabling adaption to chang ing circumstancesand engagement with diverse actors and sectors were important in these increasingly pluralistic environments. Faced with growing demands for health workers, inadequate supply and di culties with migration and retention, and shortages in remote rural areas, every country and region has developed Panel 9: Action points Countries of low and middle income can make substantial improvements to delivery of health care, despite limited resources, and can increase coverage and augment health in the long term. Investment and political initiatives, both globally and nationally, should address four aims to boost the chances of success. Actions to strengthen systems can include: Building capacity with skilled individuals who have the ability to inspire and are supported by strong institutions Promotion of continuity by providing the stability necessary for reforms to be seen through to completion, coupled with the institutional memory that helps to learn lessons amid changing priorities Identication of catalysts for change and to seize windows of opportunity to promote key reforms and build broad political support Ensuring that policies are responsive to needs and social values and are adapted to the circumstances of the country in question, and to make sure that learning can be achieved across countries facing similar situations Health systems research should take a longer term approach in view of the social, economic, and political context in which social institutions (in the health sector or beyond) are embedded, which would also help to account for their success or failure. Comparative research can inform policies seeking to achieve universal coverage and create opportunities for learning across countries sharing similar geographic and socioeconomic characteristics. Health Policy 2130 www.thelancet.com Vol 381 June 15, 2013 innovative strategies to increase the size and skills of the health workforce and improve retention in underserved and rural areas. We have shown that progress was possible in the ve study countries under dierent health nancing arrange ments. In all places, expansion of nancial risk protection was acknowledged to be necessary; Thailand and Kyrgyzstan have achieved universal coverage where- as Bangladesh and Tamil Nadu are only just beginning, with Ethiopia making some progress from a low baseline in a short time. Advances in maternal and child health outcomes and access to services were achieved despite high levels of out-of-pocket payments in several coun- tries. A new nding was the importance of building resilience into the health system, making a response to political turmoil, economic crises, and natural disasters easier. What we have added with our study is new evidence on the factors that enabled these ve countries and regions to pursue pathways to good health despite political and economic constraints. We have identied broad principles translated into practical policies that facilitate progress in improving health and delivering health care, which are likely to be applicable elsewhere. Our key conclusion is that four interlinked elements were common to all study countries (panel 9): capacity, comprising skilled and frequently inspirational individuals, supported by strong institutions; continuity, providing the stability necessary for reforms to be seen through to completion coupled with the institutional memory that helps to learn lessons amid changing priorities; catalysts for change, or seizing of windows of opportunity; and sensitivity to context, meaning adaption of policies to the circumstances of the country in question rather than simply being transplanted from somewhere else. Although these fundamentals might not guarantee sustained progress, if they are all present health gains are more likely. Strategic investment in health systems remains key to accelerate and sustain the achievements in health and access to essential services reported here. Continued health system development will allow countries to move beyond picking the low-hanging fruit that make up the common causes of childhood death, onto tackling chronic diseases that are accelerated by growing urbanisation and changing lifestyles. This reorientation could well require increases in funds and other resource inputs that health systems need, if high-quality services are to be available to all population groups at an aordable cost and if health systems are to respond to growing population expectations. Contributors DB, MM, and AH wrote the rst draft of the paper. All authors then made equal contributions to writing and further clarications. DB, MM, AM, and LC made extensive revisions and produced the nal version. All authors contributed ideas to the study, its design, and data analysis leading to this report. Conicts of interest We declare that we have no conicts of interest. Acknowledgments We thank the Rockefeller Foundation for continued support, as part of the Good Health at Low Cost 2011 project, particularly Ariel Pablos-Mendes, Stefan Nachuk, Lily Dorment, and Mushtaque Chowdhury; the steering committee, particularly Gill Walt, Carine Ronsmans, Simon Cousens, and Ulla Gri ths, for valuable guidance on framing the research questions, study design, and interpretation of ndings; and the experts who participated in the Bellagio project meeting in 2010, who advised on the comparative chapters. This study was funded by the Rockefeller Foundation. The opinions expressed in this report do not necessarily reect the policies of the London School of Hygiene and Tropical Medicine or the Rockefeller Foundation. The study was approved by the ethics committee of the London School of Hygiene and Tropical Medicine (GHLC 5560 04.08.09). All study countries obtained approval from their national ethics committees. References 1 Halstead S, Walsh J, Warren K. Good health at low cost. Bellagio: Rockefeller Foundation, 1985. 2 Balabanova D, McKee M, Mills A. Good health at low cost 25 years on. London: London School of Hygiene and Tropical Medicine, 2011. 3 World Bank. World development indicators. Sept 28, 2012. http:// data.worldbank.org/data-catalog/world-development-indicators (accessed Jan 25, 2012). 4 Government of India. Economic survey of India, 201011. New Delhi: Government of India, 2010. 5 United Nations, Department of Economic and Social Aairs. World population prospects: the 2010 revision. Dec 6, 2012. http://esa. un.org/unpd/wpp/index.htm (accessed Jan 25, 2012). 6 Chandramouli C. Census of India 2011: provisional population totals, India series 1. New Delhi: O ce of the Registrar General and Census Commissioner, 2011. 7 WHO. World health statistics 2011. 2011. http://www.who.int/gho/ publications/world_health_statistics/EN_WHS2011_Full.pdf (accessed Feb 5, 2013). 8 Registrar General of India. Sample registration system (SRS): SRS bulletin, vol 46 no 1. December, 2011. http://censusindia.gov. in/Vital_Statistics/SRS_Bulletins/SRS_Bulletin_December_2011. pdf (accessed Feb 5, 2013). 9 Registrar General of India. Maternal and child mortality and total fertility rates: sample registration system (SRS). July 7, 2011. http:// censusindia.gov.in/Vital_Statistics/SRS_Bulletins/MMR_ release_070711.pdf (accessed Feb 5, 2013). 10 National Institute of Population Research and Training (NIPORT), MEASURE Evaluation, UNC-CH USA, International Centre for Diarrhoeal Disease Research Bangladesh (ICDDR B). Bangladesh: maternal mortality and health care survey 2010preliminary results. February, 2011. http://transition.usaid.gov/bd/les/C6%20 BMMS%20Survey%202010.pdf (accessed Dec 7, 2012). 11 Registrar General of India. Special bulletin on maternal mortality in India, 200709. June, 2011. http://www.censusindia.gov.in/ vital_statistics/SRS_Bulletins/Final-MMR%20Bulletin-2007-09_ 070711.pdf (accessed Feb 5, 2013). 12 O ce of the Registrar General and Census Commissioner. Population projections for India and states 20012026: report of the technical group on population projections constituted by the National Commission on Population. May, 2006. http://nrhm-mis. nic.in/UI/Public%20Periodic/Population_Projection_Report_2006. pdf (accessed Feb 5, 2013). 13 Federal Democratic Republic of Ethiopia, Federal HIV/AIDS Prevention and Control O ce. Report on progress towards implementation of the UN Declaration of Commitment on HIV/AIDS. March, 2010. http://data.unaids.org/pub/Report/2010/ ethiopia_2010_country_progress_report_en.pdf (accessed Feb 5, 2013). 14 National AIDS Control Organisation, Ministry of Health and Welfare, Government of India. HIV sentinel surveillance and HIV estimation in India 2007: a technical brief. October, 2008. http:// www.nacoonline.org/upload/Publication/M&E%20Surveillance, %20Research/HIV%20Sentinel%20Surveillance%20and%20 HIV%20Estimation%202007_A%20Technical%20Brief.pdf (accessed Feb 5, 2013). Health Policy www.thelancet.com Vol 381 June 15, 2013 2131 36 Chowdhury Z. The politics of essential drugs: the making of a successful health strategy: lessons from Bangladesh. Dhaka: University Press, 1996. 37 Koehlmoos TP. Evidence aid and the disaster response in Pakistan and Haiti. Cochrane Database Syst Rev 2010; 2011: ED000014. 38 Meredith M. The State of Africa: a history of fty years of independence. London: Free Press, 2006. 39 Ethiopia Federal Ministry of Health. Health and health related indicators. Addis Ababa: Federal Ministry of Health, Planning and Programming Department, 2008. 40 Sebastian MS, Lemma H. E ciency of the health extension programme in Tigray, Ethiopia: a data envelopment analysis. BMC Int Health Hum Rights 2010; 10: 16. 41 Negusse H, McAulie E, MacLachlan M. Initial community perspectives on the Health Service Extension Programme in Welkait, Ethiopia. Hum Resour Health 2007; 5: 21. 42 Central Statistical Agency (Ethiopia), ORC Macro. Ethiopia: demographic and health survey, 2005. September, 2006. http:// www.measuredhs.com/pubs/pdf/FR179/FR179[23June2011].pdf (accessed Dec 10, 2012). 43 Ministry of Finance and Economic Development. Ethiopia: building on progressa plan for accelerated and sustained development to end poverty (PASDEP). Addis Ababa: Ministry of Finance and Economic Development, 2006. 44 Dercon S, Gilligan DO, Hoddinott J, Woldehanna T. The impact of agricultural extension and roads on poverty and consumption growth in fteen Ethiopian villages. December, 2008. http://www. ifpri.org/sites/default/les/publications/ifpridp00840.pdf (accessed Dec 10, 2012). 45 Banteyerga H, Kidanu A, Hotchkiss D, De S, Tharaney M, Callahan K. The system-wide eects of the scale-up of HIV/AIDs, tuberculosis, and malaria services in Ethiopia. Oct 1, 2010. http:// www.healthsystems2020.org/content/resource/detail/2744/ (accessed Dec 10, 2012). 46 Rechel B, Ahmedov M, Akkazieva B, Katsaga A, Khodjamurodov G, McKee M. Lessons from two decades of health reform in Central Asia. Health Policy Plan 2012; 27: 28187. 47 Kutzin J. A descriptive framework for country-level analysis of health care nancing arrangements. Health Policy 2001; 56: 171204. 48 WHO Regional O ce for Europe. European health for all database (HFA-DB). July, 2012. http://data.euro.who.int/hfadb/ (accessed Jan 31, 2013). 49 Bhutta ZA, Khan YP, Maternal and newborn health in Kyrgyzstan and Chui oblast: assessment and implications for interventions. Karachi: Division of Women and Child Health, The Aga Khan University, 2009. 50 Ministry of Health. Evaluation of national health programme Manas Taalimi. Bishkek: Ministry of Health, 2011. 51 Falkingham J, Akkazieva B, Baschieri A. Trends in out-of-pocket payments for health care in Kyrgyzstan, 20012007. Health Policy Plan 2010; 25: 42736. 52 Kutzin J. Health expenditures, reforms and policy priorities for the Kyrgyz Republic. March, 2003. http://www.hpac.kg/images/pdf/ PERJKforPRP24.pdf (accessed Dec 10, 2012). 53 Abdraimova A, Beran D. Report on the rapid assessment protocol for insulin access in Kyrgyzstan. London: International Insulin Foundation, 2009. 54 Registrar General of India. Sample registration system: special bulletin on maternal mortality in India 200406. New Delhi: O ce of The Registrar General and Census Commissioner, 2009. 55 WHO Regional O ce for South-East Asia. Safer pregnancy in Tamil Nadu: from vision to reality. 2009. http://www.searo.who.int/ LinkFiles/Making_Pregnancy_Safer_Safer_Pregnancy_in_Tamil_ Nadu.pdf (accessed Dec 10, 2012). 56 DANIDA. Country report India: evaluation of Danish bilateral assistance to health 198897. Copenhagen: Danish International Development Agency, 1999. 57 Gaudin S, Yazbeck AS. Immunization in India 19931999: wealth, gender, and regional inequalities revisited. Soc Sci Med 2006; 62: 694706. 58 Bennett S, Muraleedharan V. New public management and health care in the third world. Econ Polit Wkly 2000; 35: 5968. 15 Rao KD, Bhatnagar A, Berman P, Saran I, Raha S. HRH technical report 1: Indias health workforcesize, composition and distribution. 2008. http://www.hrhindia.org/assets/images/ Paper-I.pdf (accessed Dec 7, 2012). 16 Government of Tamil Nadu. Statistical hand book 2011. Chennai: Department of Economics and Statistics, Tamil Nadu, 2011. 17 WHO. National health accounts, country health information. March, 2011. http://www.who.int/nha/country/en/ (accessed Jan 25, 2012). 18 Government of India. National health accounts, India 200405. September, 2009. http://planningcommission.nic.in/reports/ genrep/health/National_Health_Account_04_05.pdf (accessed Feb 5, 2013). 19 Social Security Department, International Labour Organization. Issues in social protection, discussion paper 19: social health protectionan ILO strategy towards universal access to health care, a consultation. August, 2007. http://www.ilo.org/public/english/ protection/secsoc/downloads/healthpolicy.pdf (accessed Dec 7, 2012). 20 Ibraimova A, Akkazieva B, Ibraimov A, Manzhieva E, Rechel B. Kyrgyzstan: health system review. Health Syst Transit 2011; 13: 1152. 21 Government of Tamil Nadu. Annual policy notes, 19902005. Chennai: Department of Health and Family Welfare, 19902005. 22 National Institute of Population Research and Training (NIPORT), Mitra and Associates, and Macro International. Bangladesh: demographic and health survey, 2007. March, 2009, http://www. measuredhs.com/pubs/pdf/FR207/FR207[April-10-2009].pdf (accessed Dec 7, 2012). 23 Central Statistical Agency, ICF Macro. Ethiopia demographic and health survey 2011: preliminary report. September, 2011. http://www. measuredhs.com/pubs/pdf/PR10/PR10.pdf (accessed Dec 7, 2012). 24 National Statistical Committee of the Kyrgyz Republic, UNICEF. Kyrgyzstan: monitoring the situation of children and women multiple indicator cluster survey, Kyrgyz Republic, 2006. 2007. http://www.childinfo.org/les/MICS3_Kyrgyzstan_ FinalReport_2005-06_Eng.pdf (accessed Dec 7, 2012). 25 International Institute for Population Sciences, Macro International. National family health survey (NFHS-3), 200506, India: volume 1. http://www.measuredhs.com/pubs/pdf/ FRIND3/FRIND3-Vol1andVol2.pdf (accessed Jan 17, 2013). 26 Thailand National Statistical O ce. Monitoring the situation of children and women: Thailand multiple indicator cluster survey, December 2005February 2006nal report. 2006. http://www. childinfo.org/les/MICS3_Thailand_FinalReport_2005-06_Eng.pdf (accessed Feb 5, 2013). 27 International Institute for Population Sciences, Macro International. National family health survey (NFHS-3), India, 200506: Tamil Nadu. August, 2008. http://www.rchiips.org/NFHS/ NFHS-3%20Data/TamilNadu_report.pdf (accessed Jan 17, 2013). 28 Blood AK. The cruel birth of Bangladesh. Dhaka: The University Press Limited, 2002. 29 Islam S. History of Bangladesh 17041971: vol 1, political history. Dhaka: Asiatic Society of Bangladesh, 1992. 30 WHO Country O ce for Bangladesh. WHO country cooperation strategy 20082013: Bangladesh. 2007. http://www.who.int/ countryfocus/cooperation_strategy/ccs_bgd_en.pdf (accessed Dec 10, 2012). 31 WHO Regional O ce for South-East Asia, 11 health questions about the 11 SEAR countries. 2007. http://www.searo.who.int/ LinkFiles/Country_Health_System_Prole_11health-questions.pdf (accessed Dec 10, 2012). 32 Chowdhury ME, Ahmed A, Kalim N, Koblinsky M. Causes of maternal mortality decline in Matlab, Bangladesh. J Health Popul Nutr 2009; 27: 10823. 33 Expanded Programme on Immunization (Bangladesh). Bangladesh EPI coverage evaluation survey, 2009. Dhaka: Expanded Programme on Immunization, Directorate General of Health Services, 2009. 34 Directorate General of Drug Administration. List of local allopathic pharmaceutical manufacturers. Dhaka: Directorate General of Drug Administration and the Ministry of Health and Family Welfare, 2010. 35 Sundewall J, Forsberg BC, Tomson G. Theory and practice: a case study of coordination and ownership in the Bangladesh health SWAp. Health Res Policy Syst 2006; 4: 5. Health Policy 2132 www.thelancet.com Vol 381 June 15, 2013 59 Lalitha N. Tamil Nadu government intervention and prices of medicine. Econ Polit Wkly 2008; 43: 6671. 60 Narayana D. Intensifying infant mortality inequality in India and a reversal by policy intervention. J Hum Dev Capabil 2008; 9: 26581. 61 Guilmoto CZ, Rajan SI. Fertility transition in South India. London: Sage, 2005. 62 Ravindran TKS. Female autonomy in Tamil Nadu: unravelling the complexities. Econ Polit Wkly 1999; 34: WS3444. 63 Das Gupta M, Desikachari BR, Somanathan TV, Padmanaban P. How to improve public health systems: lessons from Tamil Nadu. October, 2009, http://elibrary.worldbank.org/content/workingpaper/ 1 0.1596/1813-9450-5073 (accessed Dec 10, 2012). 64 Institute for Health Metrics and Evaluation. Infant and child mortality estimates by country 19702010. Seattle: Institute for Health Metrics and Evaluation, 2010. 65 Rohde J, Cousens S, Chopra M, et al. 30 years after Alma-Ata: has primary health care worked in countries? Lancet 2008; 372: 95061. 66 Thailand National Statistical O ce. Expectation of life at birth from the survey of population change. 2007. http://web.nso.go.th/eng/ en/stat/popchang/popchgt5.htm (accessed Dec 15, 2011). 67 Bureau of Policy and Strategy. Thailand health prole 20012004. Bangkok: Ministry of Public Health, 2008. 68 Prachuabmoh V, Mithranon P. Below-replacement fertility in Thailand and its policy implications. J Popul Res 2003; 20: 3550. 69 United Nations. MDG-Plus: a case study of Thailand. New York: United Nations Development Programme, 2011. 70 Tangcharoensathien V. From targeting to universality: lessons from the health system in Thailand. In: Townsend P, ed. Building decent societies: rethinking the role of social security in development. Basingstoke: Palgrave Macmillan, 2009: pp 30121. 71 Wibulpolprasert S. Twenty-ve years of rural doctor movement in Thailand. Bangkok: Srangsue, 2003. 72 Russell S, Bennett S, Mills A. Reforming the health sector: towards a healthy new public management. J Int Dev 1999; 11: 76775. 73 Pitayarangsarit S, Tangcharoensathien V. Sustaining capacity in health policy and systems research in Thailand. Bull World Health Organ 2009; 87: 724. 74 Pitayarangsarit S, Tangcharoensathien V. Capacity development for health policy and systems research: experience and lessons from Thailand. In: Green G, Bennett S, eds. Sound choices: enhancing capacity for evidence-informed health policy. Geneva: World Health Organization, 2007: pp 14766. 75 de Savigny D, Adam T. Systems thinking for health systems strengthening. Geneva: Alliance for Health Policy and Systems Research, 2009. 76 McPake B, Blaauw D, Shea R. Recognising patterns: health systems research beyond controlled trials (HSD/WP/10/06). London: Health Systems Development Programme, 2006. 77 Gilson L. Health policy and systems research: a methodology reader. Geneva: World Health Organization, 2012. 78 Tissot L, Veyrassat B. Technological trajectories, markets, institutions: industrialized countries, 19th20th centuries. Bern: Peter Lang, 2002. 79 Castleden M, McKee M, Murray V, Leonardi G. Resilience thinking in health protection. J Public Health (Oxf) 2011; 33: 36977. 80 WHO. Everybodys business: strengthening health systems to improve health outcomesWHOs framework for action. Geneva: World Health Organization, 2007. 81 Travis P, Bennett S, Haines A, et al. Overcoming health-systems constraints to achieve the Millennium Development Goals. Lancet 2004; 364: 90006. 82 Atun R, de Jongh T, Secci F, Ohiri K, Adeyi O. Integration of targeted health interventions into health systems: a conceptual framework for analysis. Health Policy Plan 2010; 25: 10411. 83 Yin RK. Case study research: design and methods. Thousand Oaks: Sage Publications, 2003. 84 Arksey H, OMalley L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol 2005; 8: 1932. 85 Harbison S, Robinson WC. Rural electrication and fertility change. Popul Res Policy Rev 1985; 4: 14971. 86 Ahmed R, Hossain M. Development impact of rural infrastructure in Bangladesh. October, 1990. http://www.ifpri.org/sites/default/ les/publications/rr83.pdf (accessed Dec 10, 2012). 87 Sen G, Ostlin P. Unequal, unfair, ineective and ine cient: gender inequality in healthwhy it exists and how we can change it. Stockholm: Karolinska Institute, 2007. 88 United Nations Development Program. Human development report 2010: The real wealth of nations: pathways to human development. Washington: United Nations, 2010. 89 Pitt M, Khandker S, Cartwright J. Empowering women with micro nance: evidence from Bangladesh. Econ Dev Cult Change 2006; 54: 791831. 90 Hamid SA, Roberts J, Mosley P. Can micro health insurance reduce poverty? Evidence from Bangladesh. January, 2010. http://www. shef.ac.uk/content/1/c6/10/45/13/SERPS2010001.pdf (accessed Dec 10, 2012). 91 Gakidou E, Cowling K, Lozano R, Murray CJL. Increased educational attainment and its eect on child mortality in 175 countries between 1970 and 2009: a systematic analysis. Lancet 2010; 376: 95974. 92 Dev SM, James KS, Sen B. Causes of fertility decline in India and Bangladesh: an investigation. October, 2002. http://saneinetwork. net/Files/02_01.pdf (accessed Dec 10, 2012). 93 DFID. The politics of poverty: elites, citizens and statesndings from ten years of DFID-funded research on governance and fragile states 20012010. London: Department for International Development, 2010. 94 Siddiqi S, Masud TI, Nishtar S, et al. Framework for assessing governance of the health system in developing countries: gateway to good governance. Health Policy 2009; 90: 1325. 95 Finkelstein LS. What is global governance? Glob Gov 1995; 1: 36772. 96 WHO. The world health report 2000: health systemsimproving performance. Geneva: World Health Organization, 2000. 97 Brinkerho DW, Bossert TJ. Health governance: concepts, experience, and programming options. Bethesda: Health Systems 20/20, 2008. 98 Mirzoev T, Green A, Newell J. Health swaps and external aid: a case study from Tajikistan. Int J Health Plann Manage 2010; 25: 27086. 99 Datiko D, Lindtjrn B. Health extension workers improve tuberculosis case detection and treatment success in southern Ethiopia: a community randomized trial. PLoS One 2009; 4: e5443. 100 Wakabi W. Extension workers drive Ethiopias primary health care. Lancet 2008; 372: 880. 101 Cercone J, Pacheco Jimenez J. Costa Rica: Good practice in expanding health care coverage: lessons from reforms in low- and middle-income countries. In: Gottret P, Schieber GJ, Waters HR, eds. Good practices in health nancing: lessons from reforms in low- and middle-income countries. Washington: World Bank, 2008: pp 183226. 102 Clark MA. Reinforcing a public system: health sector reform in Costa Rica. In: Kaufman RR, Nelson JM, eds. Crucial needs, weak incentives: social sector reform, democratization, and globalization in Latin America. Baltimore: Johns Hopkins University Press, 2004: pp 189216. 103 Kutzin J, Jakab M, Cashin C. Lessons from health nancing reform in central and eastern Europe and the former Soviet Union. Health Econ Policy Law 2010; 5: 13547. 104 WHO. Thailand: a country case studygood governance and preventing corruption. Geneva: World Health Organization, 2010. 105 Planning Commission, Government of India. High level expert group report on universal health coverage for India: instituted by planning commission of India. November, 2011. http:// planningcommission.nic.in/reports/genrep/rep_uhc0812.pdf (accessed Nov 20, 2012). 106 Padmanaban P, Raman PS, Mavalankar DV. Innovations and challenges in reducing maternal mortality in Tamil Nadu, India. J Health Popul Nutr 2009; 27: 20219. 107 Human Rights Watch. No tally of the anguish: accountability in maternal health care in India. New York: Human Rights Watch, 2009. 108 Jindawatana A Wibulpolprasert S. The rst Thai national health assembly. Bangkok: Ministry of Public Health, 1988. 109 Chowdhury M, Bhuiya, A. The wider impacts of BRAC poverty alleviation programme in Bangladesh. J Int Dev 2004; 16: 36986. Health Policy www.thelancet.com Vol 381 June 15, 2013 2133 110 Koehlmoos T, Rashid M, Rahman Z, Cravioto A, Hanney S. Understanding the role of evidence in policy making in Bangladesh: report 1an analysis of interviews with health sector decision makers. Aug 15, 2009. http://www.who.int/alliance-hpsr/projects/ alliancehpsr_snpreport1bang09.pdf (accessed Nov 20, 2012). 111 Fulton BD, Sche er RM, Sparkes SP, Auh EY, Vujicic M, Soucat A. Health workforce skill mix and task shifting in low income countries: a review of recent evidence. Hum Resour Health 2011; 9: 1. 112 Admassie A, Abebaw D, Woldemichael A. Impact evaluation of the Ethiopian health services extension program: a non-experimental approach. October, 2009. http://depot.gdnet.org/newkb/ submissions/Health%20Project_22.pdf (accessed Nov 21, 2012). 113 UNICEF. In rural Ethiopia, health extension workers bring care to new mothers. Aug 6, 2010. http://www.unicef.org/infobycountry/ ethiopia_55449.html (accessed Nov 21, 2012). 114 Assefa Y, Jerene D, Lulseged S, Ooms G, Van Damme W. Rapid scale-up of antiretroviral treatment in Ethiopia: successes and system-wide eects. PLoS Med 2009; 6: e1000056. 115 Mahmood S, Iqbal M, Hanni S, Wahed T, Bhuiya A. Are village doctors in Bangladesh a blessing or a curse? BMC Int Health Hum Rights 2010; 10: 18. 116 Bhuiya A. Village health care providers in Matlab, Bangladesh: a study of their knowledge in the management of childhood diarrhoea. J Diarrhoeal Dis Res 1992; 10: 1015. 117 Dolea C, Stormont L, Braichet JM. Evaluated strategies to increase attraction and retention of health workers in remote and rural areas. Bull World Health Organ 2010; 88: 37985. 118 Ooms G, Decoster K, Miti K, et al. Crowding out: are relations between international health aid and government health funding too complex to be captured in averages only? Lancet 2010; 375: 140305. 119 The 20092010 NHA working group. National Health Accounts of Thailand 20092010. Bangkok: International Health Policy Program, Ministry of Public Health, 2012. 120 Jakab M, Kutzin J. Improving nancial protection in Kyrgyzstan through reducing informal payments: evidence from 200106 (policy research paper #57). Bishkek: Health Policy Analysis Unit (DFID/WHO), 2009. 121 Gertler P, Gruber J. Insuring consumption against illness. Am Econ Rev 2002; 92: 5170. 122 Wagsta A. The economic consequences of health shocks: evidence from Vietnam. J Health Econ 2007; 26: 82100. 123 WHO. Primary health care: now more than ever. Geneva: World Health Organization, 2008. 124 Redwood-Campbell L, Abrahams J. Primary health care and disasters: the current state of the literature: what we know, gaps and next steps. Prehosp Disaster Med 2011; 26: 18491. 125 Mills A. Health policy and systems research: dening the terrain; identifying the methods. Health Policy Plan 2012; 27: 1. 126 Stareld B. Primary care: balancing health needs, services, and technology. New York: Oxford University Press, 1998. 127 Commission on Social Determinants of Health. Closing the gap in a generation: health equity through action on the social determinants of healthnal report of the Commission on Social Determinants of Health. Geneva: World Health Organization, 2008. 128 Sindall C. Intersectoral collaboration: the best of times, the worst of times. Health Promot Int 1997; 12: 56.