7/15/2014 A simple questionnaire to detect hypermobil... [Int J Clin Pract.

2003] - PubMed - NCBI

http://www.ncbi.nlm.nih.gov/pubmed?term=12723715 1/2
Int J Clin Pract. 2003 Apr;57(3):163-6.
A simple questionnaire to detect hypermobility: an adjunct to the
assessment of patients with diffuse musculoskeletal pain.
Hakim AJ , Grahame R.
Abstract
The aim of the study was to develop a simple and reproducible self-reporting questionnaire that
identifies individuals with hypermobility. Two hundred and twelve consecutive hypermobile female
new attendees to the hypermobility clinic at two London teaching hospitals and a random selection
of 57 healthy volunteers completed a 10-part questionnaire. Questions were selected from clinical
experience (RG), and assessed musculoskeletal symptoms and past and present physical agility.
Of the 212 cases, 30 were hypermobile with no other underlying disorder and 182 fulfilled the
1998 Brighton criteria for benign joint hypermobility syndrome (BJHS). Odds ratios for the
presence of hypermobility were calculated for each question. Six questions were found to be
significant and the model of 'best fit' for sensitivity and specificity contained five of these. To
demonstrate the reproducibility of the five-part questionnaire a second cohort of 170 hypermobile
cases with BJHS and 50 controls was surveyed. Analysis demonstrated that a positive answer to
any two questions in the five-part questionnaire gave the highest combined sensitivity and
specificity for detecting hypermobility. The sensitivity and specificity was 84% and 89%
respectively in the first cohort and reproduced with values of 84% and 80% in the second cohort.
Overall the questionnaire correctly identified 84% of all cases and controls. This simple and
reproducible questionnaire for detecting hypermobility could be of particular use as an adjunct in
the clinical assessment of chronic, diffuse pain syndromes where hypermobility is often missed yet
is potentially treatable.
PMID: 12723715 [PubMed - indexed for MEDLINE]
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Author information
Publication Types
Multicenter Study
MeSH Terms
Adolescent
Adult
Aged
Aged, 80 and over
Publication Types, MeSH Terms, Grant Support
PubMed 12723715[uid]
7/15/2014 A simple questionnaire to detect hypermobil... [Int J Clin Pract. 2003] - PubMed - NCBI
http://www.ncbi.nlm.nih.gov/pubmed?term=12723715 2/2
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Female
Humans
Joint Instability/diagnosis*
Middle Aged
Odds Ratio
Pain/diagnosis
Questionnaires/standards*
Reproducibility of Results
Sensitivity and Specificity
Grant Support
17489/Arthritis Research UK/United Kingdom