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Letrozole

Posted on October 13, 2013 by Maxim Peptide


Letrozole is a peptide that is considered to be a non-steroidal
aromatase inhibitor. It is sometimes referred to as Femara.
Mechanics of Letrozole
Scientific study that has been conducted on animal test subjects has
determined that Letrozole is classified as an aromatase inhibitor.
This means that the peptide has the ability to block the enzyme that
naturally synthesizes estrogen.
strogens are e!pressed by the con"ersion of androgens "ia the
aciti"ity of the aromatase enzyme. strogens# in turn# bind to an
estrogen receptor# $hen then promotes cellular di"ision. %o$e"er#
Letrozole&s functionality is such that it pre"ents the aromatase from
producing estrogens by competiti"e# re"ersible binding to its
cytochrome '()* unit. This particular action is specific# and the
peptide itself does not lo$er the production of mineralo- or
corticosteroids.
Theoretical Benefits of Letrozole
Scientific research conducted on animal test subjects in relation to Letrozole has determined that the peptide could
pro"ide se"eral theoretical benefits.
The primary focus on the scientific study has been in relation to Letrozole&s potential ability to treat breast cancer in
female animal test subjects $ho are postmenopausal. Scientific studies on animal test subjects ha"e concluded
that the presence of estrogen is needed in order for specific types of breast cancers to gro$ and proliferate. These
types of cancers come $ith estrogen receptors# and the intake of this secretion enables the cancers to proliferate.
+ecause of the peptide&s ability to block estrogen receptors# this inherently slo$s do$n the spread of the cancer.
,nother theoretical benefit that Letrozole has been thought to ha"e is in relation to the treatment of gynecomastia-
that is the benign enlargement of breast tissue in male animal test subjects.
,dditionally# the peptide has been determined to be able to treat endometriosis. This is a gynecological condition in
$hich the cells from the lining of the uterus .that is# the endometrium/ appear and gro$ outside the uterine ca"ity#
most commonly on the membrane $hich lines the abdominal ca"ity# thus resulting in pain and infertility in animal
test subjects.
Potential Negative Side Effects of Letrozole
0hile scientific research conducted on animal test subjects ha"e determined se"eral theoretical benefits in relation
to Letrozole# there ha"e also been a fe$ potential negati"e side effects that ha"e been associated $ith the peptide.
The most notable negati"e side effect in relation to Letrozole is the peptide&s relationship $ith bones. The
peptide&s ability to prohibit the release of estrogen in female animal test subjects inad"ertently leads to a loss of
bone density o"er a period of time. This loss of bone density# in turn# can lead to an increased chance of broken
Click here to buy Letrozole in our store
bones# fractures# and other bone-related ailments. ,dditionally# scientific study on animal test subjects has
determined that the use of Letrozole could lead to the causation or the $orsening of osteoporosis- the progressi"e
bone disease that is marked by a decrease in bone mass# an increase in bone fragility# and a deterioration of bone
microarchitecture.
Some of the other serious potential negati"e side effects that ha"e been linked to Letrozole include the follo$ing1
2hest pain
3ash
%i"es
4ifficulty breathing
5nusual bleeding
5nusual bruising
6ello$ing of the skin
6ello$ing of the eyes
Flu-like symptoms
'ain in the upper right portion of the stomach
'ain# $armth# or hea"iness in the back of the lo$er leg
Se"ere headache
Sudden $eakness or numbness in e!tremities
2on"ersely# some of the less se"ere negati"e side effects that has been linked to the use of Letrozole include1
7ight s$eats
7ausea
8omiting
Loss of appetite
4iarrhea
2onstipation
%eartburn
'ain in stomach
Muscle pain
9oint pain
+one pain
!cessi"e tiredness or fatigue
2hanges in $eight
%eadache
4izziness
0eakness
S$elling of e!tremities
4ifficulty falling asleep
4ifficulty staying asleep
8aginal bleeding
8aginal irritation
+lurry "ision
For Scientific Use Only
,lthough there ha"e been a host of scientific studies conducted on animal test subjects in order to determine
Letrozole&s range of operational mechanics# theoretical benefits# and negati"e side effects# it should be noted that
all findings that are associated $ith the peptide are still considered to be the product of current laboratory research.
+ecause Letrozole l is currently in the research phase# any study or usage associated $ith the mechanics#
operations# benefits# and side effects of the peptide should solely be contained to the restrictions of a strictly
controlled en"ironment such as a laboratory or a medical research facility.

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