NCI Sect 04 Breast

SEER Cancer Statistics Review 1975-2010
Table 4.1
Cancer of the Female Breast (Invasive)
Trends in SEER Incidenceab and U.S. Mortalityc Using the Joinpoint Regression Program,
1975-2010 With up to Five Joinpoints, 1992-2010 With up to Three Joinpoints,
All Ages by Race/Ethnicity
JP Trend 1
JP Trend 2
Years
APC
Years
APC
SEER 9 Delay-Adjusted Incidencea, 1975-2010
All Races
1975-80 -0.6
1980-87
4.0*
White
1975-80 -0.5
1980-87
4.1*
Black
1975-92
2.2*
1992-10
0.1
SEER 13 Delay-Adjusted Incidenceb, 1992-2010
All Races
1992-99
1.3*
1999-04
White
1992-99
1.5*
1999-04
Black
1992-10
0.2*
SEER 9 Observed Incidencea, 1975-2010
All Races
1975-80 -0.5
1980-87
White
1975-80 -0.5
1980-87
Black
1975-92
2.2*
1992-10
SEER 13 Observed Incidenceb, 1992-2010
All Races
1992-99
1.3*
1999-04
White
1992-99
1.5*
1999-04
ef
White NH
1992-99
1.7*
1999-04
Black
1992-10
0.1
Black NHef
1992-10
0.2
APIe
1992-94 -4.3
1994-97
AI/ANeg
1992-10 -0.3
Hispanicf
1992-99
1.3
1999-10
U.S. Cancer Mortalityc, 1975-2010
All Races
1975-90
0.4*
White
1975-90
0.3*
Black
1975-93
1.4*
All Races
1992-95 -1.3*
White
1992-95 -1.5*
White NHef
1992-95 -1.6*
Black
1992-95
0.4
ef
Black NH
1992-10 -1.2*
APIe
1992-10 -1.0*
AI/ANeg
1992-10 -0.4
f
Hispanic
1992-10 -1.7*
National Cancer Institute
a
b
c
d
e
f
*
-
JP Trend 3
Years
APC
1987-94
1987-94
-0.2
-0.2
-2.2*
-2.3*
2004-10
2004-10
0.2
0.1
4.0*
4.1*
0.1
1987-94
1987-94
-0.2
-0.2
-2.2*
-2.4*
-2.3*
2004-10
2004-10
2004-10
0.1
-0.1
0.1
5.8
1997-10
0.0
JP Trend 4
Years
APC
1994-99
1994-99
1994-99
1994-99
1.8*
2.0*
1.8*
2.0*
-0.6*
1990-95
1990-95
1993-10
-1.8*
-2.0*
-1.5*
1995-98
1995-98
-3.2*
-3.5*
1995-98
1995-98
1995-98
1995-10
-3.4*
-3.6*
-3.5*
-1.6*
1998-10
1998-10
1998-10
-1.9*
-1.9*
-1.8*
1998-10
1998-10
-1.9*
-1.9*
JP Trend 5
Years
APC
1999-04
1999-04
1999-04
1999-04
-2.2*
-2.3*
-2.3*
-2.4*
JP Trend 6
Years
APC
2004-10
2004-10
2004-10
2004-10
0.2
0.1
0.1
-0.1
AAPCd
2001-10 2006-10
-0.6
-0.7*
0.1
0.2
0.1
0.1
-0.6
-0.7
0.2*
0.2
0.1
0.2*
-0.7
-0.8*
0.1
0.1
-0.1
0.1
-0.7
-0.8*
-0.7
0.1
0.2
0.0
-0.3
-0.6*
0.1
-0.1
0.1
0.1
0.2
0.0
-0.3
-0.6*
-1.9*
-1.9*
-1.5*
-1.9*
-1.9*
-1.5*
-1.9*
-1.9*
-1.8*
-1.6*
-1.2*
-1.0*
-0.4
-1.7*
-1.9*
-1.9*
-1.8*
-1.6*
-1.2*
-1.0*
-0.4
-1.7*
Joinpoint Regression Program Version 4.0.3, April 2013, National Cancer Institute. (http://surveillance.cancer.gov/joinpoint/).
The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).
Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).
Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.
The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.
API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic
Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska
Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.
The Hispanic and Non-Hispanic mortality trends exclude deaths from CT, DC, ME, MD, MN, NH, NY, ND, SC, OK and VT.
Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.
The APC/AAPC is significantly different from zero (p<.05).
Joinpoint regression line analysis could not be performed on data series.
Table 4.2
Ages <50 by Race/Ethnicity
JP Trend 1
JP Trend 2
Years
APC
Years
APC
All Races
1975-80 -1.5
1980-85
3.2*
White
1975-80 -1.1
1980-87
2.7*
Black
1975-77 -6.1
1977-90
1.8*
All Races
1992-10
0.1
White
1992-10
0.1*
Black
1992-01 -1.1
2001-10
JP Trend 3
Years
APC
1985-10
1987-94
1990-10
0.0
-0.8
-0.3
JP Trend 4
Years
APC
1994-10
0.3*
0.9
JP Trend 5
Years
APC
JP Trend 6
Years
APC
AAPCd
2001-10 2006-10
0.0
0.3*
-0.3
0.0
0.3*
-0.3
0.1
0.1*
0.9
0.1
0.1*
0.9
0.0
0.2*
-0.3
0.0
0.2*
-0.3
0.1
0.1
0.4*
0.4
0.7
0.8*
0.0
-0.1
0.1
0.1
0.4*
-1.3
-1.1
0.8*
0.0
-0.1
-3.1*
-2.6*
-2.5*
-3.1*
-2.6*
-2.5*
-3.0*
-3.2*
-3.1*
-2.4*
-2.3*
-2.8*
-2.7*
-3.0*
-3.0*
-3.2*
-3.1*
-2.4*
-2.3*
-2.8*
-2.7*
-3.0*
SEER 9 Observed Incidence , 1975-2010

All Races
1975-80 -1.5
1980-85
White
1975-80 -1.1
1980-87
Black
1975-91
1.3*
1991-10
All Races
1992-10
0.1
White
1992-10
0.1
ef
White NH
1992-10
0.4*
Black
1992-02 -1.4*
2002-05
Black NHef
1992-02 -1.4*
2002-05
e
API
1992-10
0.8*
AI/ANeg
1992-10
0.0
Hispanicf
1992-10 -0.1
All Races
1975-90 -0.4*
White
1975-91 -0.7*
Black
1975-87
1.8*
All Races
1992-10 -3.0*
White
1992-10 -3.2*
White NHef
1992-10 -3.1*
Black
1992-10 -2.4*
ef
Black NH
1992-10 -2.3*
APIe
1992-10 -2.8*
AI/ANeg
1992-10 -2.7*
f
Hispanic
1992-10 -3.0*
a
b
c
d
e
f
*
-
1990-10
1991-99
1987-96
3.2*
2.6*
-0.3
1985-10
1987-94
0.0
-0.8
4.1
4.6
2005-10
2005-10
-1.3
-1.1
-3.1*
-4.3*
-1.2*
1999-10
1996-10
-2.6*
-2.5*
1994-10
0.2*
Table 4.3
Ages 50+ by Race/Ethnicity
JP Trend 1
JP Trend 2
Years
APC
Years
APC
All Races
1975-82
0.8
1982-87
5.4*
White
1975-82
0.9
1982-87
5.6*
Black
1975-92
2.6*
1992-10
0.3
All Races
1992-99
1.7*
1999-04
White
1992-00
1.5*
2000-04
Black
1992-10
0.3*
All Races
1975-82
0.9
1982-87
White
1975-82
0.9*
1982-87
Black
1975-92
2.6*
1992-10

All Races
1992-94 -0.4
White
1992-94 -0.6
White NHef
1992-94 -0.5
Black
1992-94
1.9
ef
Black NH
1992-10 -0.9*
APIe
1992-10 -0.5*
AI/ANeg
1992-10
0.1
f
Hispanic
1992-10 -1.5*
a
b
c
d
e
f
*
-
1987-93
1987-93
-0.3
-0.4
-2.8*
-3.7*
2004-10
2004-10
0.1
0.1
5.3*
5.5*
0.2
1987-93
1987-93
-0.3
-0.3
-2.9*
-3.7*
-5.2
2004-10
2004-10
2004-10
0.0
0.0
0.3
8.3
1997-04
-1.5
JP Trend 4
Years
APC
1993-99
1993-99
2005-10
2004-10
0.5
0.3
0.4
-0.1
-0.8
-1.0*
0.3
0.5
0.3
0.3
-0.9
-1.2*
0.3*
0.1
0.1
0.3*
-0.7*
1990-10
1990-10
1993-10
-1.9*
-2.0*
-1.2*
-1.9*
-2.0*
-1.2*
-1.9*
-2.0*
-1.2*
1994-97
1994-97
1994-97
1994-10
-3.1*
-3.3*
-3.3*
-1.3*
-1.8*
-1.9*
-1.7*
-1.3*
-0.9*
-0.5*
0.1
-1.5*
-1.8*
-1.9*
-1.7*
-1.3*
-0.9*
-0.5*
0.1
-1.5*
-1.8*
-1.9*
-1.7*
-2.6*
-3.8*
2005-10
2005-10
0.0
0.0
0.3
0.2
0.2
1.3
-0.3
-0.7*
1.3
1999-05
2000-04
-2.5*
-2.6*
AAPCd
2001-10 2006-10
-1.0*
-1.3*
-1.6
0.2
0.2
0.3
-0.3
-0.7*
2004-10
1.9*
1.7*
1999-05
1999-05
JP Trend 6
Years
APC
0.4
-0.1
0.2
1997-10
1997-10
1997-10
1993-99
1993-00
1.9*
2.1*
JP Trend 5
Years
APC
-0.9*
-1.3*
0.2

All Races
1992-99
1.7*
1999-04
White
1992-00
1.4*
2000-04
ef
White NH
1992-01
1.3*
2001-04
Black
1992-10
0.2
Black NHef
1992-10
0.2
APIe
1992-94 -5.6
1994-97
AI/ANeg
1992-10 -0.3
Hispanicf
1992-99
1.5
1999-10
All Races
1975-90
0.6*
White
1975-90
0.5*
Black
1975-93
1.6*
JP Trend 3
Years
APC
Table 4.4
Cancer of the Female Breast (In Situ)
Trends in SEER Incidenceab Using the Joinpoint Regression Program,
All Ages by Race/Ethnicity
JP Trend 1
JP Trend 2
Years
APC
Years
APC
All Races
1975-81 -3.2
1981-87 25.1*
White
1975-81 -2.7
1981-87 25.0*
Black
1975-98
9.4*
1998-10
1.6*
All Races
1992-99
7.1*
1999-10
White
1992-99
7.0*
1999-10
Black
1992-98
8.9*
1998-10
0.7
0.5
1.8*

All Races
1975-81 -3.1
1981-87
White
1975-81 -2.9
1981-87
Black
1975-81
3.1
1981-88
25.2*
25.4*
18.4*

All Races
1992-99
7.1*
1999-10
White
1992-99
7.0*
1999-10
ef
White NH
1992-99
7.3*
1999-10
Black
1992-98
8.9*
1998-10
Black NHef
1992-98
8.7*
1998-10
e
API
1992-02
7.8*
2002-05
AI/ANeg
1992-10
0.8
Hispanicf
1992-98
8.3*
1998-10
a
b
c
d
e
f
*
-
0.6
0.4
0.6
1.8*
1.9*
-5.4
1.6*
JP Trend 3
Years
APC
1987-94
1987-95
1987-94
1987-95
1988-98
2005-08
3.8*
4.0*
3.8*
3.9*
7.9*
8.6
JP Trend 4
Years
APC
1994-98
1995-98
1994-98
1995-98
1998-10
2008-10
9.9*
11.3*
9.9*
11.4
1.8*
-3.8
JP Trend 5
Years
APC
1998-10
1998-10
1998-10
1998-10
1.0*
0.8*
0.9*
0.7*
JP Trend 6
Years
APC
AAPCd
2001-10 2006-10
1.0*
0.8*
1.6*
1.0*
0.8*
1.6*
0.7
0.5
1.8*
0.7
0.5
1.8*
0.9*
0.7*
1.8*
0.9*
0.7*
1.8*
0.6
0.4
0.6
1.8*
1.9*
0.9
0.8
1.6*
0.6
0.4
0.6
1.8*
1.9*
2.2
0.8
1.6*
Table 4.5
Cancer of the Breast (Invasive)
Age-adjusted SEER Incidencea Rates by Year, Race and Sex
Total
Year of Diagnosis:
1975-2010
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
68.85
58.06
56.44
55.99
55.85
56.85
56.91
59.32
59.23
61.91
64.49
69.13
70.49
74.80
73.08
70.75
73.17
74.10
73.03
71.33
72.10
72.85
73.34
75.57
77.31
77.17
74.34
75.56
73.62
68.85
69.34
68.32
68.07
68.95
68.88
70.11
67.71
All Races
Males
1.09
0.85
1.10
0.96
0.90
0.99
0.90
1.00
0.98
1.04
0.93
0.95
0.95
0.96
1.22
1.13
1.13
1.12
1.04
1.08
1.14
0.97
1.31
1.10
1.07
0.98
1.16
1.22
1.15
1.32
1.21
1.09
1.22
1.11
1.18
1.22
1.25
Females
Total
Whites
Males
Females
Total
Blacks
Males
Females
125.48
105.07
101.92
100.83
100.64
102.13
102.25
106.35
106.48
111.16
116.01
124.28
126.88
134.51
131.31
127.21
131.84
133.86
132.05
129.20
130.98
132.63
133.68
137.96
141.35
141.47
136.42
138.69
135.64
126.85
128.00
126.42
125.98
127.89
127.99
130.27
126.02
70.64
59.45
58.12
57.47
57.57
58.31
58.55
61.26
61.10
63.73
66.60
71.02
72.32
77.84
75.63
73.39
75.35
76.64
74.76
73.18
74.29
75.16
75.34
77.65
79.72
79.60
77.24
78.21
75.93
70.82
70.83
70.22
69.51
70.35
69.75
71.04
68.78
1.09
0.88
1.12
0.88
0.89
0.94
0.93
0.93
0.94
1.13
0.94
0.97
0.96
0.98
1.16
1.08
1.15
1.17
1.02
1.04
1.09
0.93
1.32
1.07
1.12
0.97
1.14
1.22
1.13
1.34
1.25
1.19
1.26
1.13
1.21
1.27
1.12
129.39
107.33
104.80
103.44
103.67
104.75
105.15
109.95
110.01
114.50
119.94
127.88
130.44
140.31
136.33
132.40
136.26
138.92
135.78
133.16
135.69
137.68
138.14
142.75
146.73
147.11
142.97
144.88
141.24
131.76
132.07
131.31
130.11
132.11
131.16
133.62
129.77
66.36
52.11
48.04
49.67
48.18
49.88
50.55
54.34
53.88
58.95
58.42
64.13
66.22
63.08
68.99
60.52
68.55
67.37
71.59
68.79
70.64
71.61
71.68
72.33
71.14
72.50
68.01
66.55
70.87
71.09
71.27
67.83
71.32
71.50
72.95
73.47
69.56
1.63
2.76
2.86
1.66
1.95
1.74
1.61
1.54
1.82
1.37
3.04
115.44
93.58
85.36
87.03
85.92
86.90
89.40
94.20
93.47
103.58
102.47
111.71
114.97
109.46
118.65
104.92
118.63
117.33
124.02
119.39
122.53
123.72
124.35
125.04
123.96
125.47
117.20
115.26
122.95
123.44
123.90
118.22
124.29
123.97
127.17
128.07
120.55
SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).
Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
Statistic not shown. Rate based on less than 16 cases for the time interval.
Table 4.6
Age-adjusted U.S. Deatha Rates by Year, Race and Sex
Total
Year of Death:
1975-2010
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
16.28
17.83
18.06
18.47
18.05
17.74
18.04
18.20
18.39
18.33
18.79
18.84
18.76
18.66
18.98
19.00
18.93
18.66
18.07
17.98
17.67
17.44
16.83
16.07
15.67
15.18
15.19
14.77
14.54
14.31
13.82
13.61
13.25
12.90
12.66
12.43
12.26
All Races
Males
0.32
0.37
0.38
0.36
0.36
0.28
0.30
0.32
0.33
0.31
0.29
0.34
0.28
0.34
0.33
0.33
0.28
0.28
0.31
0.36
0.35
0.35
0.34
0.32
0.32
0.34
0.37
0.35
0.31
0.31
0.29
0.29
0.29
0.28
0.31
0.28
0.30
Females
Total
Whites
Males
Females
Total
Blacks
Males
Females
28.67
31.45
31.80
32.48
31.73
31.21
31.68
31.92
32.19
32.07
32.90
32.98
32.87
32.66
33.20
33.23
33.14
32.69
31.64
31.39
30.92
30.55
29.49
28.21
27.54
26.61
26.64
26.01
25.62
25.27
24.49
24.14
23.56
22.96
22.55
22.24
21.92
16.12
18.03
18.25
18.56
18.12
17.87
18.15
18.28
18.42
18.36
18.76
18.88
18.76
18.57
18.85
18.95
18.79
18.46
17.89
17.74
17.40
17.11
16.52
15.67
15.32
14.77
14.86
14.37
14.13
13.89
13.44
13.18
12.87
12.51
12.26
12.09
11.85
0.31
0.38
0.36
0.35
0.35
0.26
0.30
0.31
0.32
0.29
0.28
0.34
0.27
0.34
0.28
0.33
0.26
0.27
0.30
0.34
0.34
0.32
0.31
0.30
0.31
0.32
0.35
0.33
0.29
0.30
0.28
0.28
0.29
0.27
0.29
0.28
0.28
28.50
31.79
32.17
32.67
31.90
31.48
31.93
32.12
32.31
32.20
32.90
33.11
32.93
32.57
33.09
33.23
33.02
32.45
31.43
31.09
30.56
30.09
29.05
27.62
27.01
25.98
26.17
25.43
25.02
24.66
23.94
23.49
23.02
22.40
21.99
21.76
21.33
20.10
16.82
17.61
18.90
18.63
17.87
18.37
18.95
19.68
19.57
20.97
20.35
20.69
21.53
22.35
21.56
22.49
22.62
21.88
22.62
22.44
22.70
22.09
22.25
21.08
20.93
20.48
20.52
20.32
20.24
19.11
19.37
18.73
18.51
18.37
17.78
17.78
0.55
0.41
0.60
0.51
0.60
0.54
0.42
0.46
0.56
0.50
0.47
0.43
0.42
0.47
0.88
0.45
0.52
0.44
0.45
0.66
0.60
0.77
0.72
0.63
0.56
0.69
0.63
0.65
0.61
0.47
0.56
0.49
0.47
0.45
0.60
0.41
0.59
34.13
29.49
30.47
32.80
32.14
30.82
31.68
32.55
33.75
33.53
35.94
34.85
35.44
36.73
37.78
36.61
38.00
38.28
37.09
38.04
37.74
38.18
37.13
37.43
35.53
35.21
34.36
34.52
34.14
34.10
32.29
32.81
31.62
31.36
30.96
30.19
30.17
US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.
Table 4.7
Delay-adjusted SEER Incidencea Rates by Year, Race and Age
All Races, Females
<50
50+
All
Year of Diagnosis:
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
105.07
101.92
100.83
100.64
102.13
102.25
106.35
106.49
111.18
116.03
124.30
126.92
134.56
131.36
127.28
131.92
133.94
132.15
129.31
131.10
132.76
133.83
138.13
141.54
141.71
136.69
138.99
135.97
127.20
128.41
126.88
126.52
128.51
128.71
131.13
127.40
40.62
40.03
39.11
38.85
38.04
37.82
39.22
40.57
40.27
42.38
44.38
44.53
45.55
44.01
43.41
45.61
47.28
43.49
42.88
42.45
43.24
43.59
43.58
45.49
43.89
43.54
44.03
42.92
43.42
45.04
44.18
44.26
45.34
45.58
45.59
44.28
273.82
263.98
262.44
262.45
269.96
270.96
282.13
279.09
296.85
308.90
333.59
342.66
367.63
360.08
346.89
357.91
360.87
364.30
355.61
363.24
367.17
370.14
385.73
393.06
397.86
380.59
387.67
379.63
346.59
346.74
343.45
341.91
346.30
346.40
355.13
345.04
All
107.33
104.80
103.44
103.67
104.75
105.15
109.95
110.02
114.52
119.98
127.93
130.50
140.39
136.42
132.52
136.40
139.08
135.95
133.35
135.90
137.91
138.40
143.03
147.05
147.49
143.38
145.34
141.74
132.28
132.65
131.95
130.82
132.92
132.17
134.99
131.87
White Females
<50
50+
All
Black Females
<50
40.68
40.83
39.40
39.34
38.63
38.31
40.16
41.31
40.91
43.15
44.50
45.29
46.56
45.08
44.55
45.42
47.32
43.69
43.37
42.83
43.85
44.07
44.23
45.78
45.23
44.09
44.96
43.69
44.46
45.05
44.70
45.27
45.95
45.91
46.15
45.47
281.86
272.31
271.12
272.15
277.88
280.15
292.70
289.93
307.28
321.15
346.40
353.64
386.11
375.61
362.87
374.62
379.36
377.54
368.97
379.60
384.22
385.40
401.76
412.22
415.27
403.39
408.18
398.50
362.26
362.03
360.43
354.86
360.66
358.04
367.60
358.13
93.58
85.36
87.03
85.92
86.90
89.40
94.20
93.49
103.62
102.53
111.80
115.08
109.59
118.80
105.11
118.88
117.59
124.33
119.73
122.91
124.15
124.82
125.56
124.50
126.12
117.87
115.98
123.79
124.37
124.93
119.30
125.55
125.35
128.90
130.31
123.73
42.98
37.85
37.62
40.01
37.85
37.69
38.66
38.02
41.39
44.69
45.56
45.69
43.19
42.84
42.24
49.00
50.97
47.17
45.23
47.67
45.62
44.44
44.48
46.79
44.00
44.88
40.02
41.43
43.49
47.89
45.94
45.55
45.38
45.18
46.24
44.61
Additional information on the model used to delay-adjust SEER Incidence rates can be found at
(http://surveillance.cancer.gov/delay/).
Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval.
50+
226.09
209.77
216.41
206.14
215.34
224.82
239.64
238.73
266.58
253.99
285.25
296.80
283.47
317.70
269.75
301.86
292.05
326.40
314.81
319.93
329.77
335.29
337.85
327.99
341.17
308.99
314.90
339.47
336.15
326.64
311.38
335.03
334.76
348.13
350.43
330.91
Table 4.8
Delay-adjusted SEER Incidencea Rates by Year, Race and Age
All Races, Females
<50
50+
All
Year of Diagnosis:
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
5.83
5.28
4.25
4.40
4.58
4.83
4.96
5.30
6.09
8.63
11.53
13.63
17.38
17.58
16.55
19.15
19.80
21.44
20.72
22.32
24.72
25.38
28.33
32.81
32.78
32.86
33.72
34.08
32.52
33.23
32.74
33.35
35.50
37.00
37.19
34.21
3.80
2.72
2.56
2.36
2.81
2.98
2.64
2.73
3.03
4.79
5.93
6.79
7.82
8.20
7.04
8.39
8.78
9.01
8.37
8.73
9.64
9.84
11.05
12.00
11.99
11.81
11.58
11.92
12.05
12.79
12.52
13.88
14.45
14.22
14.54
13.25
11.15
11.98
8.67
9.74
9.21
9.67
11.05
12.03
14.09
18.66
26.20
31.56
42.40
42.14
41.46
47.32
48.65
53.99
53.05
57.89
64.21
66.08
73.58
87.32
87.20
87.99
91.70
92.11
86.12
86.76
85.66
84.35
90.62
96.66
96.51
89.10
All
White Females
<50
50+
All
Black Females
<50
5.90
5.36
4.32
4.55
4.65
5.06
4.93
5.34
6.22
9.19
12.11
14.27
18.22
18.11
17.11
19.93
20.51
22.19
21.36
22.91
25.11
25.94
28.97
33.78
33.22
33.94
34.29
34.64
33.54
34.05
33.74
33.72
35.97
37.35
37.98
34.55
3.84
2.89
2.59
2.50
2.85
3.11
2.52
2.71
3.03
5.19
6.27
7.23
8.24
8.50
7.27
8.73
8.90
9.27
8.81
9.02
10.03
9.84
11.23
12.34
12.24
12.56
12.04
12.35
12.58
13.04
13.08
14.46
14.90
14.85
15.18
13.30
11.28
11.83
8.85
9.91
9.37
10.17
11.26
12.24
14.57
19.64
27.39
32.70
44.35
43.28
42.86
49.27
50.90
56.01
54.25
59.27
64.61
68.09
75.43
89.93
88.17
89.92
92.56
93.01
88.44
89.08
87.85
84.18
91.14
96.28
97.70
90.19
3.94
3.28
3.03
3.29
4.78
3.56
4.08
5.55
5.41
6.35
8.21
9.32
12.30
15.99
14.54
14.99
15.42
19.09
16.74
20.16
22.83
22.76
28.31
30.46
29.68
29.80
31.91
28.67
29.97
30.68
31.86
35.90
33.63
36.58
35.87
33.39
2.73
2.37
3.49
5.12
5.64
7.38
5.52
5.54
7.30
6.83
6.06
7.48
6.51
7.72
11.41
10.69
10.40
8.06
9.03
8.70
9.44
10.13
10.21
11.69
11.04
11.62
11.45
12.32
Additional information on the model used to delay-adjust SEER Incidence rates can be found at
(http://surveillance.cancer.gov/delay/).
Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval.
50+
8.31
9.40
9.55
8.72
12.94
13.20
16.77
20.58
20.33
29.74
38.55
38.16
39.72
36.69
51.20
44.70
53.37
65.56
62.15
72.58
82.22
80.16
86.74
91.83
80.96
83.72
84.50
88.53
99.30
92.79
101.95
99.82
88.56
Table 4.9
Age-adjusted SEER Incidencea Rates by Year, Race and Age
All Races, Females
<50
50+
All
Year of Diagnosis:
1975-2010
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
125.48
105.07
101.92
100.83
100.64
102.13
102.25
106.35
106.48
111.16
116.01
124.28
126.88
134.51
131.31
127.21
131.84
133.86
132.05
129.20
130.98
132.63
133.68
137.96
141.35
141.47
136.42
138.69
135.64
126.85
128.00
126.42
125.98
127.89
127.99
130.27
126.02
43.34
40.62
40.03
39.11
38.85
38.04
37.82
39.22
40.57
40.27
42.37
44.37
44.51
45.53
43.99
43.39
45.59
47.25
43.46
42.85
42.41
43.20
43.54
43.53
45.43
43.81
43.46
43.93
42.81
43.30
44.89
44.02
44.07
45.12
45.33
45.29
43.80
340.57
273.82
263.98
262.44
262.45
269.96
270.96
282.13
279.08
296.81
308.85
333.51
342.57
367.50
359.95
346.71
357.71
360.64
364.04
355.32
362.91
366.79
369.72
385.24
392.53
397.18
379.86
386.83
378.70
345.62
345.64
342.20
340.47
344.61
344.44
352.79
341.31
All
129.39
107.33
104.80
103.44
103.67
104.75
105.15
109.95
110.01
114.50
119.94
127.88
130.44
140.31
136.33
132.40
136.26
138.92
135.78
133.16
135.69
137.68
138.14
142.75
146.73
147.11
142.97
144.88
141.24
131.76
132.07
131.31
130.11
132.11
131.16
133.62
129.77
White Females
<50
50+
All
Black Females
<50
43.85
40.68
40.83
39.40
39.34
38.63
38.31
40.16
41.31
40.90
43.14
44.48
45.27
46.53
45.05
44.51
45.38
47.27
43.63
43.31
42.77
43.77
43.99
44.14
45.68
45.11
43.96
44.82
43.54
44.28
44.85
44.48
45.02
45.66
45.56
45.69
44.74
353.37
281.86
272.31
271.12
272.15
277.88
280.15
292.70
289.91
307.22
321.05
346.26
353.48
385.90
375.38
362.56
374.25
378.94
377.07
368.46
379.03
383.57
384.69
400.95
411.34
414.18
402.23
406.88
397.09
360.84
360.45
358.67
352.92
358.46
355.30
363.89
352.42
115.44
93.58
85.36
87.03
85.92
86.90
89.40
94.20
93.47
103.58
102.47
111.71
114.97
109.46
118.65
104.92
118.63
117.33
124.02
119.39
122.53
123.72
124.35
125.04
123.96
125.47
117.20
115.26
122.95
123.44
123.90
118.22
124.29
123.97
127.17
128.07
120.55
44.05
42.98
37.85
37.62
40.01
37.85
37.69
38.66
38.02
41.37
44.66
45.52
45.64
43.13
42.79
42.16
48.90
50.86
47.05
45.10
47.52
45.46
44.27
44.30
46.59
43.77
44.62
39.77
41.14
43.16
47.50
45.53
45.09
44.88
44.58
45.45
43.47
50+
302.38
226.09
209.77
216.41
206.14
215.34
224.82
239.64
238.68
266.47
253.83
285.02
296.50
283.13
317.29
269.26
301.23
291.38
325.56
313.92
318.93
328.63
334.04
336.47
326.58
339.40
307.24
312.95
337.16
333.63
323.95
308.56
331.68
331.06
343.44
344.41
322.39
Table 4.10
Age-adjusted U.S. Deatha Rates by Year, Race and Age
All Races, Females
<50
50+
All
Year of Death:
1975-2010
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
28.67
31.45
31.80
32.48
31.73
31.21
31.68
31.92
32.19
32.07
32.90
32.98
32.87
32.66
33.20
33.23
33.14
32.69
31.64
31.39
30.92
30.55
29.49
28.21
27.54
26.61
26.64
26.01
25.62
25.27
24.49
24.14
23.56
22.96
22.55
22.24
21.92
6.86
9.11
8.74
8.86
8.69
8.58
8.57
8.46
8.42
8.16
8.58
8.56
8.64
8.44
8.39
8.42
8.32
8.16
7.77
7.41
7.37
7.29
6.95
6.71
6.34
5.75
5.89
5.86
5.63
5.58
5.21
5.20
5.05
4.77
4.74
4.81
4.53
85.78
89.94
92.21
94.34
92.08
90.47
92.22
93.33
94.43
94.70
96.57
96.90
96.32
96.08
98.18
98.22
98.14
96.91
94.15
94.18
92.58
91.46
88.53
84.53
83.05
81.22
80.99
78.77
77.97
76.85
74.99
73.74
72.01
70.60
69.20
67.88
67.47
All
White Females
<50
50+
All
Black Females
<50
28.50
31.79
32.17
32.67
31.90
31.48
31.93
32.12
32.31
32.20
32.90
33.11
32.93
32.57
33.09
33.23
33.02
32.45
31.43
31.09
30.56
30.09
29.05
27.62
27.01
25.98
26.17
25.43
25.02
24.66
23.94
23.49
23.02
22.40
21.99
21.76
21.33
6.50
9.01
8.64
8.75
8.46
8.34
8.39
8.20
8.19
7.89
8.22
8.30
8.26
7.99
8.01
8.06
7.99
7.73
7.37
6.99
6.92
6.80
6.40
6.22
5.82
5.20
5.37
5.36
5.07
5.08
4.67
4.65
4.58
4.28
4.32
4.48
4.08
86.12
91.42
93.80
95.32
93.29
92.07
93.56
94.77
95.46
95.85
97.55
98.09
97.53
96.93
98.78
99.16
98.55
97.15
94.45
94.20
92.47
91.07
88.35
83.64
82.50
80.40
80.64
77.98
77.28
75.90
74.38
72.83
71.32
69.85
68.23
67.01
66.53
34.13
29.49
30.47
32.80
32.14
30.82
31.68
32.55
33.75
33.53
35.94
34.85
35.44
36.73
37.78
36.61
38.00
38.28
37.09
38.04
37.74
38.18
37.13
37.43
35.53
35.21
34.36
34.52
34.14
34.10
32.29
32.81
31.62
31.36
30.96
30.19
30.17
10.54
10.68
10.22
10.52
11.37
11.36
10.82
11.48
11.19
11.17
12.55
12.04
12.86
12.94
12.71
12.41
11.99
12.31
12.03
11.65
11.70
11.71
11.74
11.03
10.65
10.27
9.94
9.85
10.02
9.62
9.26
9.46
8.88
8.55
8.23
7.96
8.02
50+
95.91
78.75
83.50
91.13
86.53
81.78
86.31
87.74
92.83
92.10
97.21
94.58
94.58
99.04
103.42
99.96
106.13
106.29
102.73
107.14
105.91
107.49
103.61
106.56
100.68
100.52
98.31
99.12
97.31
98.19
92.60
93.95
91.17
91.10
90.47
88.39
88.17
Table 4.11
Age-adjusted SEER Incidencea Rates by Year, Race and Age
All Races, Females
<50
50+
All
Year of Diagnosis:
1975-2010
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
22.86
5.83
5.28
4.25
4.40
4.58
4.83
4.96
5.30
6.09
8.62
11.53
13.63
17.38
17.57
16.54
19.14
19.80
21.43
20.71
22.31
24.72
25.37
28.31
32.79
32.75
32.84
33.69
34.04
32.47
33.17
32.66
33.27
35.39
36.87
37.03
33.83
9.45
3.80
2.72
2.56
2.36
2.81
2.98
2.64
2.73
3.03
4.79
5.93
6.79
7.82
8.20
7.03
8.38
8.78
9.01
8.37
8.73
9.64
9.84
11.04
11.99
11.98
11.80
11.57
11.90
12.03
12.77
12.50
13.85
14.40
14.17
14.48
13.10
57.98
11.15
11.98
8.67
9.74
9.21
9.67
11.05
12.03
14.09
18.66
26.19
31.56
42.39
42.12
41.44
47.31
48.64
53.98
53.04
57.87
64.19
66.05
73.54
87.27
87.14
87.92
91.62
91.99
85.99
86.60
85.48
84.13
90.35
96.31
96.10
88.09
All
White Females
<50
50+
All
Black Females
<50
22.91
5.90
5.36
4.32
4.55
4.65
5.06
4.93
5.34
6.22
9.18
12.10
14.27
18.21
18.10
17.10
19.92
20.49
22.17
21.35
22.89
25.09
25.91
28.95
33.75
33.18
33.89
34.24
34.58
33.48
33.98
33.68
33.65
35.89
37.23
37.76
34.14
9.60
3.84
2.89
2.59
2.50
2.85
3.11
2.52
2.71
3.03
5.19
6.27
7.23
8.23
8.50
7.27
8.72
8.90
9.26
8.80
9.01
10.02
9.83
11.22
12.33
12.22
12.54
12.02
12.33
12.56
13.01
13.06
14.42
14.87
14.80
15.09
13.14
57.78
11.28
11.83
8.85
9.91
9.37
10.17
11.26
12.24
14.57
19.64
27.38
32.69
44.33
43.26
42.84
49.24
50.86
55.97
54.21
59.22
64.54
68.02
75.36
89.84
88.05
89.79
92.42
92.86
88.28
88.90
87.67
84.00
90.92
95.95
97.13
89.13
22.05
3.94
3.28
3.03
3.29
4.78
3.56
4.08
5.55
5.41
6.35
8.21
9.32
12.30
15.99
14.53
14.98
15.41
19.08
16.73
20.14
22.80
22.74
28.28
30.43
29.64
29.76
31.86
28.62
29.92
30.62
31.79
35.82
33.55
36.46
35.66
33.00
7.88
2.73
2.37
3.49
5.12
5.64
7.38
5.52
5.54
7.29
6.83
6.06
7.47
6.50
7.71
11.40
10.68
10.38
8.04
9.02
8.69
9.43
10.11
10.19
11.66
11.01
11.58
11.38
12.18
50+
59.15
8.31
9.40
9.55
8.72
12.94
13.20
16.77
20.57
20.32
29.73
38.53
38.14
39.69
36.66
51.16
44.66
53.32
65.50
62.09
72.50
82.14
80.05
86.62
91.69
80.83
83.57
84.33
88.35
99.08
92.57
101.60
99.24
87.52
Table 4.12
SEER Incidencea and U.S. Deathb Rates, Age-Adjusted and Age-Specific Rates, by Race and Sex
Total
All Races
Males
Females
Total
Whites
Males
Females
Total
Blacks
Males
Females
SEER Incidence
Age at Diagnosis
Age-Adjusted Rates, 2006-2010
All ages
Under 65
65 and over
66.8
41.8
239.9
1.2
0.4
6.7
123.8
81.6
415.8
68.0
42.0
248.2
1.2
0.4
6.7
127.4
83.0
433.9
69.3
44.2
242.5
1.9
0.7
9.7
121.4
82.3
391.5
All ages (IARC world std)c
47.3
0.8
89.4
48.1
0.7
91.9
49.1
1.2
88.0
Age-Specific Rates, 2006-2010

<1
1-4
5-9
10-14
15-19
20-24
25-29
30-34
35-39
40-44
45-49
50-54
55-59
60-64
65-69
70-74
75-79
80-84
85+
0.1
0.8
4.3
13.0
29.7
61.5
95.1
114.0
139.3
181.9
221.9
235.3
254.4
258.0
243.4
0.1
0.4
0.6
1.2
1.9
3.2
4.6
5.6
7.9
8.1
9.7
0.2
1.6
8.6
26.2
59.1
122.2
187.7
222.8
268.3
346.2
413.2
424.6
439.6
419.8
357.0
0.1
0.7
3.9
12.5
29.1
60.8
95.8
114.9
140.3
186.4
229.1
244.3
264.7
266.6
248.8
0.4
0.5
1.1
2.0
3.0
4.8
5.6
7.8
8.1
9.8
0.2
1.5
8.1
25.6
59.1
122.6
191.6
227.3
273.8
359.2
430.7
445.4
462.3
436.3
365.0
0.9
6.5
17.7
35.3
66.6
94.6
118.0
149.9
183.5
218.1
234.6
253.1
262.6
270.7
0.9
2.2
2.1
5.6
5.6
8.8
12.2
11.7
14.0
1.9
12.4
33.4
66.6
126.0
179.1
221.2
275.2
328.5
382.4
396.7
405.4
395.8
371.9
U.S. Mortality
Age at Death
All ages
Under 65
65 and over
12.7
5.8
60.6
0.3
0.1
1.7
22.6
11.2
101.8
12.3
5.4
60.3
0.3
0.1
1.6
22.1
10.5
102.0
18.2
9.5
78.4
0.5
0.2
2.7
30.8
17.5
122.8
7.9
0.2
14.6
7.6
0.2
14.2
11.8
0.3
20.7
0.1
0.3
1.4
3.5
6.8
10.9
16.3
22.6
30.1
37.3
45.1
58.5
79.6
125.3
0.0
0.1
0.1
0.2
0.4
0.7
0.9
1.2
1.7
2.4
3.6
0.1
0.7
2.8
6.9
13.5
21.4
31.7
43.4
57.1
69.5
81.8
101.6
129.6
182.6
0.0
0.3
1.2
3.1
6.1
10.0
15.2
21.2
29.3
36.7
44.6
58.5
79.4
125.4
0.1
0.1
0.2
0.4
0.7
0.8
1.2
1.6
2.4
3.5
0.1
0.6
2.4
6.2
12.3
19.8
29.9
41.2
56.2
69.2
81.6
102.5
130.2
183.1
0.1
0.7
2.9
6.8
12.4
19.1
26.4
36.7
42.8
50.9
60.5
73.7
102.4
156.5
0.5
0.8
1.2
2.2
2.2
2.2
3.3
5.1
0.2
1.4
5.5
12.8
23.3
35.9
49.1
67.0
76.6
88.1
101.8
117.9
154.2
214.4
All ages (IARC world std)c

<1
1-4
5-9
10-14
15-19
20-24
25-29
30-34
35-39
40-44
45-49
50-54
55-59
60-64
65-69
70-74
75-79
80-84
85+
a
b
c
SEER 18 areas. Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130),
unless noted.
Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130), unless noted.
Rates are per 100,000 and are age-adjusted to the IARC world standard population.
Table 4.13
Cancer of the Female Breast(In Situ)
SEER Incidencea Rates, Age-Adjusted and Age-Specific Rates, by Race

All Races, Females
Age at Diagnosis:
All ages
Under 65
65 and over
All ages (IARC world std)b

Age at Diagnosis:
<1
1-4
5-9
10-14
15-19
20-24
25-29
30-34
35-39
40-44
45-49
50-54
55-59
60-64
65-69
70-74
75-79
80-84
85+
a
b
White Females
Black Females
31.4
23.5
86.4
31.9
23.9
87.0
29.5
20.6
90.7
23.7
24.0
22.0
0.1
0.8
2.8
10.9
39.8
61.2
73.3
75.0
89.3
102.1
98.5
92.0
70.6
35.1
0.7
2.7
10.8
40.6
63.1
75.5
76.0
89.7
102.7
99.7
92.8
71.6
34.3
0.9
3.4
11.3
32.4
45.7
59.6
72.2
93.4
103.0
105.6
93.0
76.7
45.4
SEER 18 areas. Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130),
unless noted.
Rates are per 100,000 and are age-adjusted to the IARC world standard population.
Table 4.14
5-Year Relative and Period Survival (Percent) by Race, Diagnosis Year, Stage and Age
All Races, Females
All
<50
50+
All
White Females
<50
50+
All
Black Females
<50
50+
5-Year Relative Survival (Percent)

Year of Diagnosis:
1960-1963a
1970-1973a
b
1975-1977
74.8
b
1978-1980
74.4
1981-1983b
76.1
b
1984-1986
78.9
b
1987-1989
84.0
b
1990-1992
85.2
b
1993-1995
86.3
b
1996-1998
88.2
b
1999-2001
89.9
b
2003-2009
90.3f
76.5
75.5
77.4
77.8
81.4
83.4
84.2
86.5
88.2
90.3f
74.3
74.1
75.7
79.3
85.0
85.9
87.1
88.9
90.5
90.4f
63
68
75.6
75.1
77.1
80.0
85.1
86.4
87.6
89.3
91.1
91.7f
77.8
76.1
78.6
79.5
82.7
85.1
86.2
88.2
89.9
91.9f
74.9
74.8
76.7
80.1
85.9
86.9
88.1
89.7
91.5
91.7f
46
51
62.1
63.2
63.3
65.1
71.2
71.4
72.7
76.1
78.2
79.1f
62.3
67.1
64.9
64.0
69.5
70.1
70.2
73.9
76.7
79.5f
62.0
61.2
62.6
65.8
72.1
72.3
74.1
77.5
79.1
78.9f
5-Year Period Survival (Percent)cd

2009
89.5
89.5
89.5
90.6
90.7
90.6
79.7
80.1
79.5
79,804
100%
54
40
4
1
237,536
100%
63
30
6
2
257,938
100%
62
32
5
2
60,629
100%
55
40
4
1
197,309
100%
64
29
5
2
33,134
100%
52
38
8
2
10,408
100%
47
44
7
1
22,726
100%
54
35
9
2
ce
Stage Distribution (%) 2003-2009

All Stages
Number of cases
317,340
Percent
100%
Localized
61
Regional
32
Distant
5
Unstaged
2
5-Year Relative Survival (Percent), 2003-2009c

Age at Diagnosis:
Ages <45
87.7
Ages 45-54
90.1
Ages 55-64
89.9
Ages 65-74
90.5
Ages 75+
87.1
Ages <65
89.5
Ages 65+
88.9
Stagee:
All Stages
Localized
Regional
Distant
Unstaged
In Situ j
a
b
e
f
g
h
j
89.2
98.6
84.4
24.3
50.0
100.0
89.1
96.4
85.8
32.9
71.6
100.0
89.1
91.4
90.9
91.6
88.6
90.7
90.1
77.7
79.8
80.2
81.2
71.6
79.3
77.1
89.3
99.3
83.7
21.9
45.3
100.0
90.4
99.2
85.8
25.4
48.4
100.0
90.5
96.8
87.7
35.3
72.1
100.0
90.5
99.9
84.9
23.0
44.0
100.0
78.7
93.7
73.8
16.1
47.8
100.0
79.0
92.6
74.2
22.1
57.1
99.8
78.6
94.2
73.5
13.7
45.0
100.0
Based on End Results data from a series of hospital registries and one population-based registry.
SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta).
Based on follow-up of patients into 2010.
SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,
Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and
Georgia excluding ATL/RG).
Based on follow-up of patients into 2010.
Period survival provides a 2009 estimate of survival by piecing together the most recent conditional survival estimates
from several cohorts. It is computed here using three year calendar blocks (2007-2009: 0-1 year survival),
(2006-2008: 1-2 year survival), (2005-2007: 2-3 year survival), (2004-2006: 3-4 year survival), (2003-2005: 4-5 years survival).
Stage at diagnosis is classified using SEER Summary Stage 2000.
The difference between 1975-1977 and 2003-2009 is statistically significant (p<.05).
The standard error is between 5 and 10 percentage points.
The standard error is greater than 10 percentage points.
In situ cases are not included in the All Stages group.
Statistic could not be calculated due to fewer than 25 cases during the time period.
Table 4.15
SEERa Relative Survival (Percent)
By Year of Diagnosis
All Races, Females
Year of Diagnosis
1975- 1980- 19851979 1984 1989 1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
97.1
93.5
90.0
87.4
85.2
83.3
81.6
80.0
78.7
77.6
76.9
75.8
75.0
74.2
73.6
72.7
71.8
70.9
69.9
97.2
94.1
90.9
88.1
85.8
84.0
82.4
81.6
80.6
79.6
78.7
77.7
76.7
76.1
75.1
74.2
73.4
73.1
97.0
93.8
90.8
88.0
85.7
83.9
82.1
80.5
79.5
78.6
77.3
76.7
75.8
74.9
74.0
72.9
71.9
97.3
94.1
90.9
88.5
86.5
85.0
83.5
82.8
81.7
80.5
79.1
78.0
77.3
76.3
75.8
75.2
97.1
93.9
91.3
88.8
86.8
85.4
83.8
82.6
81.4
80.6
79.5
78.5
77.4
76.8
75.9
96.9
93.6
90.9
88.8
86.7
85.0
83.9
82.5
81.4
80.4
79.5
78.6
77.5
76.7
97.4
94.3
92.0
89.9
88.4
87.0
86.0
85.0
83.8
82.7
81.9
81.1
80.1
97.5
94.9
92.8
91.0
89.5
88.3
87.1
85.8
84.6
83.4
82.6
82.0
97.5
95.1
93.1
91.3
89.6
88.1
87.0
85.9
85.0
84.2
83.0
97.5
95.3
93.5
91.7
90.2
89.1
87.7
86.4
85.3
84.5
97.3
95.1
92.9
91.0
89.5
88.3
86.9
85.9
85.3
97.6
95.5
93.6
91.8
90.2
88.8
87.6
86.4
97.8
95.5
93.3
91.6
89.8
88.6
87.4
97.7
95.6
93.2
91.3
89.9
88.6
97.8
95.7
93.8
91.9
90.5
97.8
95.7
93.8
92.2
97.7
96.1
94.0
97.7
95.7
97.8
Survival Time
1-year
2-year
3-year
4-year
5-year
6-year
7-year
8-year
9-year
10-year
11-year
12-year
13-year
14-year
15-year
16-year
17-year
18-year
19-year
20-year
21-year
22-year
23-year
24-year
25-year
26-year
27-year
28-year
29-year
30-year
94.4
88.7
83.1
78.4
74.6
71.4
68.6
66.4
64.2
62.4
60.8
59.2
58.0
57.1
56.0
55.1
54.1
53.3
52.5
51.7
51.0
50.4
49.8
49.2
48.4
48.1
47.7
47.2
46.7
46.2
95.1
89.9
84.6
80.1
76.3
73.3
70.6
68.3
66.4
64.4
62.6
61.4
60.3
59.1
58.2
57.1
56.2
55.5
54.8
54.1
53.3
52.7
52.0
51.3
50.8
50.4
96.3
92.3
88.3
85.0
82.2
79.9
77.8
76.3
74.6
73.3
72.0
70.8
69.8
68.9
68.1
67.2
66.5
65.7
65.1
64.4
63.7
96.8
93.2
89.6
86.8
84.6
82.5
80.7
79.4
78.1
77.0
75.9
75.1
74.1
73.0
71.8
70.7
69.8
69.0
68.4
67.5
Based on the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).
Table 4.16
Cancer of the Female Breast (Ages <50, Invasive)
All Races, Females
Year of Diagnosis
1975- 1980- 19851979 1984 1989 1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
98.4
93.9
90.0
86.8
83.9
81.8
79.5
78.2
77.2
76.3
75.3
74.0
73.2
72.5
71.8
70.8
70.2
69.4
68.8
98.2
94.4
90.7
86.4
83.8
81.7
80.2
78.7
77.6
76.8
75.7
75.1
73.9
73.3
72.6
72.1
71.6
70.8
97.8
94.2
90.2
87.1
84.6
83.0
81.2
79.6
78.5
77.4
76.6
76.0
75.1
74.2
73.4
72.1
71.6
98.3
93.5
89.3
86.1
84.0
82.0
80.3
79.1
77.6
76.5
75.7
74.2
73.5
72.7
72.2
71.7
97.9
93.6
90.0
86.6
84.1
82.2
80.2
78.7
77.5
76.3
75.4
74.5
73.6
72.9
72.0
97.7
93.7
90.7
88.1
85.5
83.3
81.7
80.0
78.9
77.6
76.6
75.9
74.5
73.8
98.0
94.7
91.6
88.7
86.7
84.7
83.2
81.4
80.4
79.1
78.0
77.1
76.2
98.3
95.1
92.1
89.4
87.3
85.3
83.6
82.2
80.7
79.6
78.7
78.0
98.6
95.0
92.2
90.0
88.1
86.1
84.8
83.5
82.4
81.4
80.2
98.4
95.5
92.9
90.5
88.9
87.3
85.6
83.7
82.4
81.5
98.2
94.6
91.6
89.2
87.3
85.2
83.4
82.0
80.9
98.5
95.7
93.2
90.5
88.6
86.6
85.1
83.9
98.8
96.0
93.6
91.8
89.7
88.0
86.6
98.5
95.9
93.2
91.1
89.2
87.6
98.8
96.0
93.7
92.0
90.6
98.8
96.7
94.7
92.9
99.0
97.0
94.9
98.7
96.3
98.8
Survival Time
1-year
2-year
3-year
4-year
5-year
6-year
7-year
8-year
9-year
10-year
11-year
12-year
13-year
14-year
15-year
16-year
17-year
18-year
19-year
20-year
21-year
22-year
23-year
24-year
25-year
26-year
27-year
28-year
29-year
30-year
96.6
90.7
84.5
79.9
76.0
73.2
70.8
68.9
67.0
65.5
64.2
62.8
61.6
60.9
60.1
59.4
58.9
58.3
57.6
57.0
56.3
55.7
55.1
54.5
53.9
53.5
52.9
52.6
52.2
51.8
97.4
91.2
85.5
80.9
77.0
74.1
71.5
69.5
67.7
66.3
65.0
64.0
62.9
61.8
61.0
60.3
59.7
59.1
58.6
58.0
57.3
56.5
55.9
55.3
54.9
54.3
97.9
92.5
87.3
83.3
80.1
77.9
75.7
74.1
72.6
71.4
70.3
69.2
68.3
67.5
66.8
66.1
65.5
64.8
64.3
63.8
63.2
97.4
92.9
88.3
85.0
82.4
80.1
78.6
76.6
75.5
74.3
73.2
72.4
71.3
70.7
70.0
69.6
68.9
68.5
67.8
67.1
Table 4.17
Cancer of the Female Breast (Ages 50+, Invasive)
All Races, Females
Year of Diagnosis
1975- 1980- 19851979 1984 1989 1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
96.6
93.4
90.0
87.7
85.7
83.9
82.4
80.7
79.3
78.1
77.6
76.6
75.8
74.9
74.4
73.5
72.4
71.4
70.2
96.8
94.0
91.0
88.7
86.5
84.9
83.3
82.8
81.7
80.7
79.9
78.6
77.7
77.1
76.0
74.9
74.0
73.9
96.7
93.6
91.0
88.3
86.1
84.2
82.4
80.9
79.9
79.1
77.6
77.0
76.0
75.1
74.2
73.1
71.9
97.0
94.3
91.4
89.4
87.4
86.0
84.6
84.2
83.2
81.9
80.3
79.3
78.6
77.6
77.1
76.5
96.8
94.1
91.8
89.6
87.8
86.5
85.1
84.1
82.9
82.3
81.1
80.1
78.9
78.4
77.3
96.7
93.6
91.0
89.1
87.1
85.7
84.7
83.4
82.4
81.5
80.7
79.7
78.7
77.9
97.1
94.2
92.1
90.3
89.0
87.8
87.0
86.4
85.1
84.1
83.3
82.6
81.6
97.2
94.8
93.1
91.6
90.3
89.5
88.4
87.2
86.2
84.8
84.1
83.6
97.2
95.2
93.4
91.7
90.1
88.8
87.8
86.8
86.0
85.2
84.0
97.2
95.3
93.7
92.1
90.7
89.7
88.6
87.4
86.4
85.7
97.0
95.3
93.3
91.7
90.3
89.4
88.1
87.4
86.9
97.2
95.4
93.7
92.2
90.8
89.6
88.5
87.3
97.5
95.3
93.2
91.5
89.8
88.9
87.7
97.5
95.5
93.3
91.4
90.1
88.9
97.4
95.6
93.8
91.8
90.5
97.4
95.3
93.5
92.0
97.3
95.7
93.7
97.4
95.5
97.6
Survival Time
1-year
2-year
3-year
4-year
5-year
6-year
7-year
8-year
9-year
10-year
11-year
12-year
13-year
14-year
15-year
16-year
17-year
18-year
19-year
20-year
21-year
22-year
23-year
24-year
25-year
26-year
27-year
28-year
29-year
30-year
93.7
88.0
82.6
77.9
74.1
70.8
67.9
65.6
63.3
61.3
59.5
57.9
56.7
55.6
54.4
53.3
52.1
51.2
50.3
49.4
48.6
48.1
47.4
46.8
45.8
45.5
45.1
44.7
44.0
43.3
94.4
89.6
84.3
79.9
76.1
73.1
70.3
67.9
65.9
63.8
61.8
60.5
59.3
58.0
57.1
55.8
54.7
54.0
53.2
52.3
51.6
51.0
50.3
49.5
48.9
48.7
95.8
92.3
88.6
85.6
83.0
80.5
78.5
77.0
75.3
73.9
72.6
71.3
70.3
69.4
68.4
67.5
66.7
65.8
65.2
64.4
63.5
96.6
93.3
90.1
87.5
85.4
83.4
81.4
80.5
79.1
78.0
77.0
76.2
75.2
73.8
72.4
70.9
69.7
68.7
68.2
67.1
Table 4.18
Risk of Being Diagnosed With Cancer in 10, 20 and 30 Years,
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age, and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females, 2008-2010 By Race/Ethnicity
Risk of Being
Diagnosed with Cancer
+20 yrs +30 yrs
Ever
Risk of Dying
from Cancer
Race/
Ethnicity
Current
Age
+10 yrs
Risk of Being
Diagnosed with Cancer
+20 yrs +30 yrs
Ever
Race/
Ethnicity
Current
Age
+10 yrs
Risk of Dying
from Cancer
All Races
0
10
20
30
40
50
60
70
80
0.00
0.00
0.06
0.44
1.45
2.31
3.49
3.84
3.06
0.00
0.06
0.49
1.87
3.69
5.59
6.86
6.12
-
0.06
0.50
1.92
4.08
6.85
8.74
8.86
-
12.29
12.42
12.45
12.45
12.16
11.07
9.34
6.67
3.80
2.74
2.77
2.78
2.79
2.76
2.64
2.39
2.00
1.55
Asian/
Pacific
Islander
0
10
20
30
40
50
60
70
80
0.00
0.00
0.05
0.39
1.34
1.94
2.56
2.44
1.83
0.00
0.05
0.44
1.73
3.24
4.40
4.82
3.97
-
0.05
0.44
1.77
3.61
5.65
6.57
6.24
-
9.87
9.94
9.95
9.93
9.61
8.44
6.76
4.53
2.50
1.73
1.74
1.74
1.74
1.72
1.63
1.44
1.16
0.89
White
0
10
20
30
40
50
60
70
80
0.00
0.00
0.06
0.44
1.47
2.36
3.62
4.02
3.16
0.00
0.06
0.49
1.89
3.75
5.76
7.15
6.36
-
0.06
0.49
1.93
4.15
7.05
9.07
9.20
-
12.68
12.80
12.82
12.83
12.55
11.44
9.67
6.90
3.89
2.71
2.74
2.74
2.75
2.73
2.62
2.39
1.99
1.55
American
Indian/
Alaska
Nativea
0
10
20
30
40
50
60
70
80
0.00
0.00
0.05
0.21
0.82
1.61
2.38
2.58
1.16
0.00
0.05
0.26
1.02
2.37
3.83
4.64
3.45
-
0.05
0.26
1.05
2.54
4.51
5.94
5.40
-
7.38
7.46
7.49
7.52
7.44
6.89
5.66
3.74
1.55
1.73
1.75
1.76
1.78
1.78
1.75
1.58
1.30
1.06
Black
0
10
20
30
40
50
60
70
80
0.00
0.00
0.07
0.50
1.40
2.27
3.19
3.49
2.87
0.00
0.07
0.57
1.87
3.57
5.18
6.12
5.50
-
0.07
0.57
1.93
4.01
6.35
7.84
7.80
-
10.82
11.04
11.06
11.08
10.77
9.81
8.27
6.06
3.68
3.25
3.31
3.32
3.34
3.29
3.11
2.75
2.31
1.85
Hispanicb
0
10
20
30
40
50
60
70
80
0.00
0.00
0.04
0.33
1.09
1.81
2.57
2.72
2.14
0.00
0.05
0.37
1.41
2.86
4.26
5.04
4.43
-
0.04
0.37
1.45
3.16
5.25
6.61
6.59
-
9.73
9.82
9.84
9.83
9.58
8.69
7.21
5.11
2.98
2.05
2.07
2.08
2.08
2.06
1.96
1.76
1.48
1.17
Devcan 6.7.0, June 2013, National Cancer Institute (http://surveillance.cancer.gov/devcan/).

Source: Incidence data are from the SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta,
San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey,
and Georgia excluding ATL/RG). Mortality data are from the NCHS public use data file for the total US.
a
Underlying incidence and mortality data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area)
counties.
b
Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives.
Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. Underlying mortality
data for Hispanics exclude deaths from the District of Columbia, Minnesota, New Hampshire, North Dakota and South Carolina.
Statistic could not be calculated.
A percent of 0.00 represents a value that is below 0.005.
Table 4.19
SEER Incidence and U.S. Mortality
Age-Adjusted Rates and Trendsa
By Race/Ethnicity
SEER Incidence
SEER 18 Areasb
Rate 2006-2010
Rate per 100,000 persons
Females
SEER 13 Areasb
Trend 2001-2010c
AAPC (%)
Females
SEER 9 Areasb
Trend 2001-2010d
AAPC (%)
Females
RACE/ETHNICITY
All Races
123.8
-0.7
-0.7
White
White Hispanice
White Non-Hispanice
127.4
94.2
133.4
-0.8*
0.0
-0.7
-0.8*
-
Black
121.4
0.1
0.1
Asian/Pacific Islander
91.8
0.0
Amer Ind/Alaska Natf
77.1
-0.3
90.8
-0.6*
Rate 2006-2010
Trend 2001-2010h
AAPC (%)
Hispanic
U.S. Mortalityg
Females
Females
RACE/ETHNICITY
a
b
c
d
e
f
g
h
*
All Races
22.6
-1.9*
White
White Hispanice
White Non-Hispanice
22.1
15.6
22.7
-1.9*
-1.6*
-1.8*
Black
30.8
-1.6*
11.5
-1.0*
Amer Ind/Alaska Nat

Total U.S.
CHSDA Counties
Non-CHSDA Counties
12.5
15.5
8.9
-1.2*
-0.4
-2.6*
Hispanice
14.8
-1.7*
The AAPC is the Average Annual Percent Change over the time interval. The AAPCs are calculated by
the Joinpoint Regression Program Version 4.0.3, April 2013, National Cancer Institute.
Trend based on less than 10 cases for at least one year within the time interval.
Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). Trends
are based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle,
Utah, and Atlanta.
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey, Los Angeles, the Alaska
Native Registry, and Rural Georgia.
The SEER 18 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky,
Louisiana, New Jersey, and Georgia excluding ATL/RG.
The 2001-2010 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints over
diagnosis years 1992-2010.
Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific
Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics
are based on NHIA and exclude cases from the Alaska Native Registry. The 2006-2010 Hispanic and
Non-Hispanic death rates exclude deaths from the District of Columbia, North Dakota, and
South Carolina. The 2001-2010 Hispanic and Non-Hispanic mortality trends exclude deaths from
Connecticut, the District of Columbia, Maine, Maryland, Minnesota, New Hampshire, New York,
North Dakota, Oklahoma, South Carolina and Vermont.
Incidence data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service
Delivery Area) counties.
US Mortality Files, National Center for Health Statistics, CDC.
The 2001-2010 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2010.
The APC is significantly different from zero (p<.05).
Table 4.20
SEER Incidence
Age-Adjusted Rates and Trendsa
By Race/Ethnicity
SEER Incidence
SEER 18 Areasb
Rate 2006-2010
Females
SEER 13 Areasb
Trend 2001-2010c
AAPC (%)
SEER 9 Areasb
Trend 2001-2010d
AAPC (%)
Females
Females
RACE/ETHNICITY
All Races
31.4
0.6
0.9*
White
White Hispanice
White Non-Hispanice
31.9
21.1
34.1
0.4
1.7*
0.6
0.7*
-
Black
29.5
1.8*
1.8*
29.1
0.9
Amer Ind/Alaska Natf
13.7
0.8
20.6
1.6*
Hispanic
a
b
c
d
e
f
*
The AAPC is the Average Annual Percent Change over the time interval. The AAPCs are calculated by
the Joinpoint Regression Program Version 4.0.3, April 2013, National Cancer Institute.
Trend based on less than 10 cases for at least one year within the time interval.
Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). Trends
are based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle,
Utah, and Atlanta.
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey, Los Angeles, the Alaska
Native Registry, and Rural Georgia.
The SEER 18 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky,
Louisiana, New Jersey, and Georgia excluding ATL/RG.
Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific
Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics
are based on NHIA and exclude cases from the Alaska Native Registry.
Incidence data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service
Delivery Area) counties.
The APC is significantly different from zero (p<.05).
Table 4.21
Age-Adjusted SEER Incidence Ratesa
By Registry, Race and Age
All Ages
All Races
Ages <50
Ages 50+
All Ages
Whites
Ages <50
Ages 50+
All Ages
Blacks
Ages <50
Ages 50+
California
Greater Bay Area
San Francisco-Oakland
San Jose-Monterey
Los Angeles
Greater California
Connecticut
Detroit
Georgia
Atlanta
Rural Georgia
Greater Georgia
Hawaii
Iowa
Kentucky
Louisiana
New Jersey
New Mexico
Seattle-Puget Sound
Utah
122.04
127.57
129.86
123.19
115.95
122.92
136.26
126.95
121.52
130.56
129.39
116.82
123.07
123.36
121.29
119.69
129.27
108.81
137.20
110.84
40.62
44.37
45.28
42.73
39.82
39.67
50.26
44.82
43.25
47.60
49.91
40.57
47.25
43.52
41.60
41.21
47.67
37.74
44.28
36.10
335.22
345.44
351.35
333.87
315.29
340.93
361.45
342.02
326.47
347.79
337.54
316.47
321.62
332.44
329.96
325.19
342.95
294.91
380.49
306.56
127.78
139.75
142.18
135.56
119.98
127.49
138.90
128.18
122.59
135.23
138.22
117.52
132.87
123.86
120.88
118.91
133.59
113.04
142.08
112.06
41.14
46.26
47.07
44.92
39.00
40.63
51.79
45.83
42.02
48.39
54.27
39.14
47.92
43.75
41.12
39.46
49.29
39.71
44.69
36.99
354.67
384.56
391.25
372.91
332.03
354.95
367.00
343.83
333.57
362.61
358.06
322.74
355.30
333.63
329.73
326.95
354.34
305.07
397.09
308.62
120.71
120.08
123.01
98.90
124.28
117.51
110.91
126.37
120.90
130.06
111.39
114.85
128.47
114.02
129.35
124.59
117.15
83.39
122.82
96.74
40.84
40.00
40.73
35.47
43.71
38.49
39.77
43.43
47.03
48.96
45.22
45.31
46.56
38.83
46.29
46.46
43.57
37.38
42.95
-
329.87
329.78
338.46
264.99
335.26
324.43
297.20
343.53
314.32
342.42
284.66
296.95
342.96
310.91
346.85
329.19
309.82
203.89
331.97
284.24
9 SEER Areasb
11 SEER Areasb
13 SEER Areasb
18 SEER Areasb
127.63
124.72
124.74
123.79
44.72
43.42
43.44
42.62
344.74
337.62
337.62
336.34
131.34
129.11
129.14
127.38
45.33
43.81
43.83
42.96
356.56
352.46
352.51
348.44
124.75
124.32
124.11
121.35
44.69
44.37
44.37
44.11
334.42
333.65
332.89
323.61
SEER Incidence Ratesa, 2006-2010
a
b
Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah and Atlanta.
The SEER 11 areas comprise the SEER 9 areas plus San Jose-Monterey and Los Angeles.
The SEER 13 areas comprise the SEER 11 areas plus the Alaska Native Registry and Rural Georgia.
The SEER 18 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and
Georgia excluding ATL/RG.
Table 4.22
Age-Adjusted SEER Death Ratesa
All Ages
All Races
Ages <50
Ages 50+
All Ages
Whites
Ages <50
Ages 50+
All Ages
Blacks
Ages <50
Ages 50+
SEER Death Ratesa, 2006-2010

California
Greater Bay Area
San Jose-Monterey
Los Angeles
Greater California
Connecticut
Detroit
Georgia
Atlanta
Rural Georgia
Greater Georgia
Hawaii
Iowa
Kentucky
Louisiana
New Jersey
New Mexico
Seattle-Puget Sound
Utah
21.85
20.73
20.98
20.21
22.01
22.17
21.57
26.56
23.44
25.27
28.58
22.57
16.41
21.34
23.12
25.44
25.16
20.91
21.57
21.82
4.43
3.92
4.03
3.71
4.77
4.43
4.40
5.82
5.26
5.76
8.73
4.89
4.88
4.62
4.81
5.65
4.92
4.55
3.79
4.08
67.48
64.74
65.35
63.41
67.14
68.60
66.54
80.87
71.05
76.36
80.54
68.85
46.61
65.14
71.05
77.26
78.16
63.75
68.12
68.27
22.76
22.55
22.52
22.57
22.38
22.94
21.32
24.52
21.45
22.46
23.64
21.15
19.57
21.38
22.63
22.38
25.07
21.66
22.46
22.31
4.36
3.77
3.49
4.24
4.60
4.42
4.24
4.70
4.01
3.95
3.97
6.47
4.65
4.63
4.14
4.67
4.88
3.85
4.30
70.94
71.75
72.36
70.57
68.95
71.45
66.05
76.40
67.12
70.91
64.61
66.13
53.85
65.18
69.75
70.14
78.52
65.61
71.22
69.49
31.80
29.59
30.56
21.42
34.83
29.39
26.99
34.52
29.65
32.03
37.92
27.83
28.33
32.86
33.83
30.86
20.77
25.49
-
8.51
8.94
9.32
8.96
7.91
6.41
9.50
8.05
8.47
7.62
7.43
8.99
7.81
4.49
-
92.80
83.67
86.20
59.84
102.56
85.65
80.90
100.03
86.21
93.72
111.12
80.74
88.54
99.44
98.88
91.20
63.94
80.50
-
9 SEER Areasb
11 SEER Areasb
13 SEER Areasb
18 SEER Areasb
22.22
22.07
22.10
22.74
4.64
4.62
4.61
4.68
68.24
67.75
67.91
70.03
22.25
22.31
22.32
22.75
4.24
4.33
4.31
4.37
69.40
69.39
69.48
70.89
31.30
32.01
32.06
31.31
8.24
8.36
8.33
8.16
91.67
93.93
94.20
91.93
Total U.S.
22.64
4.78
69.39
22.09
4.35
68.55
30.84
8.32
89.79
a
b
Table 4.23
Age-Adjusted SEER Incidence Ratesa
All Ages
All Races
Ages <50
Ages 50+
All Ages
Whites
Ages <50
Ages 50+
All Ages
Blacks
Ages <50
Ages 50+
California
Greater Bay Area
San Jose-Monterey
Los Angeles
Greater California
Connecticut
Detroit
Georgia
Atlanta
Rural Georgia
Greater Georgia
Hawaii
Iowa
Kentucky
Louisiana
New Jersey
New Mexico
Seattle-Puget Sound
Utah
28.97
34.46
35.99
31.52
25.60
28.63
46.72
37.31
29.90
35.77
19.56
27.27
35.95
29.44
24.99
24.24
40.29
19.37
38.98
23.91
10.59
13.39
13.96
12.36
9.50
10.14
19.97
15.06
11.12
13.33
9.94
14.51
11.40
9.31
7.73
18.36
7.10
15.24
8.70
77.08
89.61
93.69
81.68
67.75
77.05
116.77
95.56
79.08
94.55
59.21
72.66
92.11
76.66
66.03
67.48
97.70
51.49
101.14
63.74
29.17
35.33
37.52
31.58
25.39
28.95
47.65
37.08
30.69
40.04
21.20
27.35
31.09
29.30
24.64
24.86
42.42
20.44
39.67
24.12
10.46
13.53
14.63
11.68
9.17
10.16
20.66
16.08
11.51
15.50
9.90
13.13
11.43
9.11
8.06
19.84
7.64
15.37
8.82
78.16
92.41
97.44
83.70
67.87
78.17
118.30
92.06
80.90
104.27
64.21
73.03
78.12
76.10
65.33
68.83
101.54
53.97
103.30
64.21
26.99
28.28
28.77
24.04
26.88
26.30
39.23
39.07
29.39
32.46
17.37
27.67
31.68
29.81
23.76
29.14
36.31
-
8.10
7.42
7.10
8.42
8.10
14.50
12.59
10.75
11.64
10.14
11.44
7.32
10.17
10.92
-
76.44
82.89
85.53
62.57
75.21
73.95
103.98
108.41
78.20
87.00
52.23
73.59
86.03
77.92
66.78
78.79
102.79
-
9 SEER Areasb
11 SEER Areasb
13 SEER Areasb
18 SEER Areasb
35.30
32.87
32.82
31.42
14.00
12.82
12.81
12.18
91.09
85.37
85.22
81.82
35.76
33.30
33.26
31.89
14.47
13.07
13.06
12.43
91.54
86.26
86.18
82.87
34.84
32.81
32.61
29.49
11.56
10.86
10.78
9.91
95.81
90.32
89.75
80.76
SEER Incidence Ratesa, 2006-2010
a
b
Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
Table 4.24
Age-Adjusted Cancer Deatha Rates By State, All Races, 2006-2010
Females
State
TOTAL U.S.
High Five States
D.C.
Louisiana
New Jersey
Ohio
Mississippi
Low Five States
South Dakota
Nebraska
Montana
Colorado
Hawaii
State
Alabama
Alaska
Arizona
Arkansas
California
Colorado
Connecticut
Delaware
D.C.
Florida
Georgia
Hawaii
Idaho
Illinois
Indiana
Iowa
Kansas
Kentucky
Louisiana
Maine
Maryland
Massachusetts
Michigan
Minnesota
Mississippi
Missouri
b
c
SE
PD
-
Rate
22.64
SE
0.05
Rank
PD
29.79
25.44
25.16
24.81
24.72
1.37
0.45
0.31
0.26
0.54
(01)
(02)
(03)
(04)
(05)
31.63c
12.39c
11.15c
9.59
9.18
20.29
20.14
19.83
19.57
16.41
0.91
0.62
0.82
0.40
0.65
(47)
(48)
(49)
(50)
(51)
-10.35c
-11.02c
-12.38c
-13.56c
-27.50c
Rate
SE
Rank
PD
23.33
24.23
20.62
23.41
21.85
19.57
21.57
22.79
29.79
21.26
23.44
16.41
21.63
23.59
23.85
21.34
22.18
23.12
25.44
20.87
24.47
21.25
23.97
20.87
24.72
24.17
0.41
1.44
0.34
0.52
0.15
0.40
0.44
0.93
1.37
0.19
0.31
0.65
0.74
0.25
0.36
0.48
0.52
0.43
0.45
0.69
0.39
0.33
0.28
0.37
0.54
0.37
(19)
(07)
(45)
(17)
(27)
(50)
(33)
(23)
(01)
(39)
(16)
(51)
(30)
(14)
(11)
(35)
(25)
(20)
(02)
(43)
(06)
(40)
(10)
(42)
(05)
(08)
3.05
7.05
-8.90
3.44
-3.46
-13.56c
-4.72
0.69
31.63c
-6.07
3.55
-27.50c
-4.44
4.21
5.38
-5.72
-2.01
2.12
12.39c
-7.81
8.10
-6.10
5.89
-7.79
9.18
6.79
State
Montana
Nebraska
Nevada
New Hampshire
New Jersey
New Mexico
New York
North Carolina
North Dakota
Ohio
Oklahoma
Oregon
Pennsylvania
Rhode Island
South Carolina
South Dakota
Tennessee
Texas
Utah
Vermont
Virginia
Washington
West Virginia
Wisconsin
Wyoming
Rate
SE
Rank
PD
19.83
20.14
22.99
21.33
25.16
20.91
22.30
23.09
21.61
24.81
23.85
21.62
23.84
20.78
23.46
20.29
23.35
21.82
21.82
20.39
24.04
21.52
22.06
21.28
21.32
0.82
0.62
0.60
0.74
0.31
0.61
0.19
0.29
1.04
0.26
0.47
0.44
0.24
0.79
0.42
0.91
0.36
0.19
0.64
1.02
0.33
0.35
0.60
0.36
1.20
(49)
(48)
(22)
(36)
(03)
(41)
(24)
(21)
(32)
(04)
(12)
(31)
(13)
(44)
(15)
(47)
(18)
(29)
(28)
(46)
(09)
(34)
(26)
(38)
(37)
-12.38c
-11.02c
1.59
-5.76
11.15c
-7.64
-1.48
2.01
-4.52
9.59
5.37
-4.48
5.31
-8.20
3.65
-10.35c
3.15
-3.60
-3.60
-9.91
6.22
-4.95
-2.53
-5.98
-5.82
US Mortality Files, National Center for Health Statistics, Centers for Disease Control and
Prevention. Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19
age groups - Census P25-1130).
Difference between state rate and total U.S. rate is statistically significant (p<=.0002).
Absolute percent difference between state rate and total U.S. rate is 10% or more.
Standard error of the rate.
Percent difference between state rate and total U.S. rate.
Table 4.25
Estimated United States Cancer Prevalence Countsa on January 1, 2010
By Race/Ethnicity, Sex and Years Since Diagnosis
Years Since Diagnosis
Race
All Racesb
Whiteb
Blackb
Asian/
Pacific
Islanderc
Hispanicd
Sex
Both Sexes
Males
Females
Both Sexes
Males
Females
Both Sexes
Males
Females
Both Sexes
Males
Females
Both Sexes
Males
Females
0 to <5
5 to <10
847,990
5,797
842,193
719,295
5,005
714,290
85,890
610
85,280
31,091
137
30,954
57,058
259
56,799
682,322
3,879
678,443
597,566
3,241
594,325
56,331
506
55,825
21,837
66
21,771
38,748
140
38,608
10 to <15
15 to <20
520,032
2,093
517,939
460,928
1,846
459,082
39,352
160
39,192
14,564
43
14,521
25,302
52
25,250
338,523
1,249
337,274
303,258
1,091
302,167
24,087
97
23,990
+
+
+
+
+
+
20 to <25
25 to <30
0 to <18e
0 to <35e
>=35g
111,063
417
110,646
100,654
401
100,253
7,561
12
7,549
+
+
+
+
+
+
2,388,868
13,018
2,375,850
2,081,047
11,183
2,069,864
205,661
1,374
204,287
72,975
280
72,695
121,107
451
120,656
2,784,496
14,436
2,770,060
2,440,716
12,478
2,428,238
230,970
1,483
229,487
+
+
+
+
+
+
59,133
152
58,981
52,282
+i
52,289
+
+
4,397
+
+
+
+
+
+
215,193
771
214,422
195,605
678
194,927
13,669
85
13,584
+
+
+
+
+
+
Completeh
2,843,629
14,588
2,829,041
2,492,998
12,471
2,480,527
+
+
233,884
+
+
+
+
+
+
Estimated prevalence percenta on January 1, 2010, of the SEER 11 population diagnosed in the previous 18 years
By Age at Prevalence, Race/Ethnicity and Sex
Age at Prevalence
Race
All Racesc
Whitec
Blackc
Asian/
Pacific
Islanderc
Hispanicd
b c d
e
f
g h i
Sex
Both Sexes
Males
Females
Both Sexes
Males
Females
Both Sexes
Males
Females
Both Sexes
Males
Females
Both Sexes
Males
Females
All Ages
0.6089%
0.0068%
1.1951%
0.6688%
0.0075%
1.3265%
0.4382%
0.0063%
0.8304%
0.4567%
0.0036%
0.8717%
0.2501%
0.0018%
0.5045%
0-9
-
10-19
20-29
Age Specific (Crude)

30-39
40-49
50-59
60-69
70-79
0.0001%
0.0002%
-
0.0061%
0.0124%
0.0057%
0.0117%
0.0082%
0.0158%
0.0061%
0.0119%
0.0040%
0.0085%
0.0863%
0.0004%
0.1723%
0.0855%
0.0004%
0.1748%
0.0983%
0.1833%
0.0818%
0.1548%
0.0620%
0.1276%
1.9094%
0.0239%
3.6146%
2.0230%
0.0250%
3.8849%
1.6418%
0.0298%
2.9161%
1.4105%
0.0112%
2.5765%
1.3380%
0.0138%
2.4598%
2.5026%
0.0408%
4.4677%
2.6788%
0.0436%
4.8349%
2.1296%
0.0413%
3.5651%
1.7091%
0.0239%
2.9922%
1.7204%
0.0220%
2.9676%
0.4609%
0.0027%
0.9149%
0.4655%
0.0025%
0.9420%
0.4615%
0.0039%
0.8665%
0.4423%
0.0021%
0.8333%
0.3194%
0.0013%
0.6499%
1.1010%
0.0083%
2.1431%
1.1356%
0.0080%
2.2471%
1.0042%
0.0150%
1.8577%
0.9828%
0.0049%
1.8207%
0.8044%
0.0040%
1.5621%
80+
2.8320%
0.0588%
4.4383%
3.0054%
0.0624%
4.7217%
2.4425%
0.0580%
3.5705%
1.7846%
0.0292%
2.8696%
1.8922%
0.0239%
2.9970%
Age-Adjustedf
All Ages
0.5873%
0.0075%
1.0793%
0.6158%
0.0078%
1.1455%
0.5256%
0.0089%
0.9111%
0.4530%
0.0042%
0.8140%
0.4133%
0.0038%
0.7515%
US 2010 cancer prevalence counts are based on 2010 cancer prevalence proportions from the SEER registries and 1/1/2010
US population estimates based on the average of 2009 and 2010 population estimates from the US Bureau of the Census.
Prevalence was calculated using the First Malignant Primary Only for a person.
Statistics based on (b) SEER 9 Areas (c) SEER 11 Areas and Rural Georgia (d) NHIA for Hispanic for SEER 11 Areas and
Rural Georgia.
Maximum limited-duration prevalence: 35 years for 1975-2010 SEER 9 data; 18 years for 1992-2010 SEER 11 data
(used to calculate prevalence for Hispanics and Asian Pacific Islanders).
Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groups.
(g) Cases diagnosed more than 35 years ago were estimated using the completeness index method (Capocaccia et. al. 1997,
Merrill et. al. 2000). (h) Complete prevalence is obtained by summing 0 to <35 and >=35. (i) Age-specific completeness index
was approximated using empirical data from historical Connecticut tumor registry.
Statistic not shown. Statistic based on fewer than 5 cases estimated alive in SEER for the time interval.
Not available.
Table 4.26
Histology
Percent Distribution and Counts by Histology among Histologically Confirmed Cases, 2006-2010
Females by Race
Asian/Pacific
American Indian/
All Races
White
Black
Islander
Alaska Nativeb
Count Percent
Count Percent
Count Percent
Count Percent
Count Percent
Carcinoma
Epidermoid carcinomad
(8051-8131)
Adenocarcinomae
Adenocarcinoma, NOS (8140)
Infiltrating duct
carcinoma (8500)
Lobular carcinoma, NOS
(8520)
Inflammatory
adenocarcinoma (8530)
Infiltrating duct mixed
and infiltrating lobular
mixed (8522-8524)
Mucinous adenocarcinoma
(8480,8482)
Mucin-producing
adenocarcinoma (8481)
Tubular adenocarcinoma
(8211)
Papillary adenocarcinoma
(8050,8260,8503,8504)
Paget disease (8540-8543)
Other adenocarcinomasf
Other specific carcinomasg
Medullary adenocarcinoma
(8510-8513)
Otherh
Unspecified, Carcinoma, NOS
(8010-8011,8020-8022)
Hispanicc
Count Percent
280,343
148
99.4%
0.1%
227,311
121
99.4%
0.1%
29,434
19
99.3%
0.1%
20,070
-
99.3%
-
1,070
-
99.0%
-
27,008
18
99.2%
0.1%
274,394
2,324
203,964
97.3%
0.8%
72.3%
222,769
1,854
163,512
97.5%
0.8%
71.5%
28,468
284
22,253
96.0%
1.0%
75.1%
19,726
136
15,655
97.6%
0.7%
77.4%
1,041
807
96.3%
74.7%
26,369
239
19,880
96.8%
0.9%
73.0%
24,403
8.7%
21,118
9.2%
1,967
6.6%
1,038
5.1%
68
6.3%
1,940
7.1%
1,233
0.4%
957
0.4%
213
0.7%
52
0.3%
164
0.6%
27,590
9.8%
23,405
10.2%
2,211
7.5%
1,637
8.1%
97
9.0%
2,747
10.1%
5,969
2.1%
4,750
2.1%
582
2.0%
551
2.7%
22
2.0%
510
1.9%
88
0.0%
68
0.0%
2,315
0.8%
2,080
0.9%
123
0.4%
1,621
0.6%
1,149
0.5%
272
1,430
3,457
2,485
1,022
0.5%
1.2%
0.9%
0.4%
1,149
2,727
1,842
702
0.5%
1.2%
0.8%
0.3%
1,463
3,316
0.5%
1.2%
1,140
2,579
0.5%
1.1%
94
0.5%
165
0.6%
0.9%
177
0.9%
177
0.7%
141
409
479
251
0.5%
1.4%
1.6%
0.8%
117
264
137
59
0.6%
1.3%
0.7%
0.3%
173
364
299
154
0.6%
1.3%
1.1%
0.6%
228
468
0.8%
1.6%
78
201
0.4%
1.0%
17
1.6%
145
322
0.5%
1.2%
Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,
Percents may not sum to 100 due to rounding.
a
Excludes Kaposi Sarcoma, mesothelioma, lymphomas, leukemias, myelomas, lymphoreticular, and immunoproliferative diseases.
b
Estimates for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.
c
Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.
d
Epidermoid carcinoma includes squamous, basal, and transitional cell carcinomas.
e
Adenocarcinoma includes histologies 8050, 8140-8147, 8160-8162, 8180-8221, 8250-8507, 8514, 8520-8551, 8560, 8570-8574, 8576,
8940-8941.
f
Other adenocarcinomas include histologies 8141-8147, 8160-8162, 8180-8210, 8212-8221, 8250-8259, 8261-8479, 8483-8499,
8501-8502, 8505-8507, 8514, 8521, 8525-8529, 8531-8539, 8544-8551, 8560, 8570-8574, 8576, 8940-8941.
g
Other specific carcinomas include histologies 8012-8015, 8030-8046, 8150-8155, 8170-8175, 8230-8249, 8508, 8510-8513,
8561-8562, 8575, 8580-8671.
h
Other includes histologies 8012-8015, 8030-8046, 8150-8155, 8170-8175, 8230-8249, 8508, 8561-8562, 8575, 8580-8671.
Statistic not shown due to fewer than 16 cases during the time period.
Table 4.26 - continued
Histology
Females by Race
Asian/Pacific
American Indian/
All Races
White
Black
Islander
Alaska Nativeb
Count Percent
Count Percent
Count Percent
Count Percent
Count Percent
Sarcoma and other soft tissue

tumors (8680-8713,8800-8921,
9040-9044,9120-9136,
9150-9252,9370-9373,
9540-9582)
Hemangiosarcomas
(9120-9126,9170)
Other sarcomasd
310
0.1%
246
0.1%
34
154
0.1%
135
0.1%
156
0.1%
111
0.0%
Other specific types

(8720-8790,8930-8936,
8950-9030,9060-9110,
9260-9365,9380-9539)
Phyllodes tumor, malignant
(9020)
Othere
747
0.3%
558
617
0.2%
130
Unspecified (8000-8005)
Totalf
0.1%
26
Hispanicc
Count Percent
0.1%
28
0.1%
0.1%
17
27
0.1%
0.2%
93
0.3%
85
0.4%
136
0.5%
464
0.2%
65
0.2%
80
0.4%
115
0.4%
0.0%
94
0.0%
28
0.1%
21
0.1%
604
0.2%
456
0.2%
78
0.3%
33
0.2%
60
0.2%
282,004
100.0%
228,571
100.0%
29,639
100.0%
20,214
100.0%
1,081
27,232
100.0%
100.0%
a
b
c
d
Other sarcomas include histologies 8680-8713, 8800-8921, 9040-9044, 9127-9136, 9150-9169, 9171-9252, 9370-9373, 9540-9582.
e
Other includes histologies 8720-8790, 8930-8936, 8950-9019, 9021-9030, 9060-9110, 9260-9365, 9380-9539.
f
Total includes carcinoma cases from the previous page.
Table 4.27
Cancer of the Female Breast(In Situ)
Histology
Females by Race
Asian/Pacific
American Indian/
All Races
White
Black
Islander
Alaska Nativeb
Count Percent
Count Percent
Count Percent
Count Percent
Count Percent
Adenocarcinomad
71,958
Adenocarcinoma in situ, NOS
(8140/2)
Ductal carcinoma in situe
60,766
Cribiform carcinoma in situ
5,963
(8201/2)
Ductal carcinoma in situ,
4,485
solid type(8230/2)
Ductal carcinoma in situ,
23,138
NOS (8500/2)
Comedocarcinoma in situ
5,406
(8501/2)
Ductal carcinoma in situ
1,206
papillary(8503/2)
Noninfiltrating intracystic
312
carcinoma(8504/2)
Ductal carcinoma in situ
1,529
micropapillary(8507/2)
Intraductal with other types 18,543
of carcinoma in situ(8523/2)
Lobular carcinoma in situ
8,296
(8520/2-8521/2, 8524/2)
Lobular carcinoma in situ,
8,269
NOS (8520/2)
Lobular CISf with other CISf
26
(8524/2)
Intraductal and lobular
2,430
in situ carcinoma (8522/2)
Other adenocarcinomasg
458
Other in situ histologies
188
Hispanicc
Count Percent
99.7%
-
57,078
-
99.7%
-
7,346
-
99.6%
-
6,471
-
99.9%
-
205
-
100.0%
-
6,352
-
99.8%
-
84.2%
8.3%
47,669
4,606
83.3%
8.0%
6,423
629
87.1%
8.5%
5,861
619
90.5%
9.6%
171
25
83.4%
12.2%
5,405
562
84.9%
8.8%
6.2%
3,651
6.4%
371
5.0%
410
6.3%
366
5.8%
32.1%
18,424
32.2%
2,486
33.7%
1,920
29.6%
65
31.7%
1,962
30.8%
7.5%
4,268
7.5%
570
7.7%
493
7.6%
19
9.3%
488
7.7%
1.7%
832
1.5%
211
2.9%
134
2.1%
121
1.9%
0.4%
208
0.4%
44
0.6%
55
0.8%
31
0.5%
2.1%
1,227
2.1%
177
2.4%
108
1.7%
128
2.0%
25.7%
14,306
25.0%
1,921
26.0%
2,101
32.4%
36
17.6%
1,728
27.2%
11.5%
7,062
12.3%
650
8.8%
378
5.8%
23
11.2%
687
10.8%
11.5%
7,039
12.3%
646
8.8%
378
5.8%
23
11.2%
687
10.8%
0.0%
23
0.0%
3.4%
1,987
3.5%
229
3.1%
0.6%
352
0.6%
44
0.3%
149
0.3%
29
178
2.7%
218
3.4%
0.6%
54
0.8%
42
0.7%
0.4%
Total
72,146 100.0%
57,227 100.0%
7,375 100.0%
6,476 100.0%
205 100.0%
6,363
a
b
c
d
Adenocarcinoma includes histologies 8050,8140-8147,8160-8162,8180-8221,8230,8250-8507,8514,8520-8551,8560,8570-8574,8576,8940-8941.
e
Ductal carcinoma includes histologies 8201, 8230, 8401, 8500-8507, 8523.
f
CIS = Carcinoma in situ.
g
Other adenocarcinomas include 8050, 8141-8147, 8160-8162, 8180-8200, 8202-8221, 8250-8400, 8402-8499, 8514, 8525-8551, 8560,
8570-8574, 8576, 8940-8941.
h
Other histologies include 8000-8049, 8051-8139, 8148-8159, 8163-8179, 8222-8229, 8231-8249, 8508-8513, 8515-8519, 8552-8559,
8561-8569, 8575, 8577-8939, 8942-9989.
100.0%
Figure 4.1
SEER Observed Incidence, SEER Delay Adjusted Incidence and US Death Rates a
Cancer of the Female Breast, by Race
White
160
Black
Rate per 100,000
160
140
Rate per 100,000

SEER Incidence APCs
Delay Adj, 1992-10 = 0.1
Observed, 1992-10 = 0.1
140
120
120
SEER Incidence APCs

Delay Adj, 2004-10 = 0.1
Observed, 2004-10 = -0.1
100
100
80
80
Delay-Adjusted Incidence
Observed Incidence
Mortality
60
60
US Mortality APC
1993-10 = -1.5*
40
40
20
20
US Mortality APC
1998-10 = -1.9*
0
1975
1980
1985
1990
1995
2000
Year of Diagnosis/Death
a
2005
2010
0
1975
1980
1985
1990
1995
2000
2005
Source: SEER 9 areas and US Mortality Files (National Center for Health Statistics, CDC).
Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).
Regression lines and APCs are calculated using the Joinpoint Regression Program Version 4.0.3, April 2013, National Cancer Institute.
The APC is the Annual Percent Change for the regression line segments. The APC shown on the graph is for the most recent trend.
* The APC is significantly different from zero (p < 0.05).
2010
Figure 4.2
SEER Observed Incidence, SEER Delay Adjusted Incidence and US Death Rates a
Cancer of the Female Breast, by Age and Race
White Ages <50
50
Rate per 100,000
Black Ages <50

50
Rate per 100,000
White Ages 50+

450
Rate per 100,000
450
400
40
30
30
350
SEER Incidence APCs
Delay Adj, 1990-10 = -0.3
Observed, 1991-10 = -0.3
300
300
Delay-Adj Incidence
250
Observed Incidence
Mortality
20
200
SEER Incidence APCs

Delay Adj, 2005-10 = 0.3
Observed, 2004-10 = -0.1
250
200
20
US Mortality APC
1999-10 = -2.6*
10
10
US Mortality APC
1996-10 = -2.5*
0
1975
1990
2000
2010
a
Rate per 100,000
400 SEER Incidence APCs

Delay Adj, 1992-10 = 0.3
Observed, 1992-10 = 0.2
350
40
SEER Incidence APCs
Delay Adj, 1994-10 = 0.3*
Observed, 1994-10 = 0.2*
Black Ages 50+
0
1975
1990
2000
150
150
100
100
50
2010
0
1975
1990
2000
US Mortality APC
1993-10 = -1.2*
50
US Mortality APC
1990-10 = -2.0*
2010
0
1975
1990
2000
2010
Figure 4.3
SEER Observed Incidence and Delay Adjusted Incidence Rates a

Cancer of the Female Breast (In Situ) , by Race
White
40
Black
Rate per 100,000
40
Rate per 100,000
SEER Incidence APCs

Delay Adj, 1998-10 = 0.8*
Observed, 1998-10 = 0.7*
SEER Incidence APCs

Delay Adj, 1998-10 = 1.6*
Observed, 1998-10 = 1.8*
35
35
30
30
25
25
20
20
15
15
10
10
Delay-Adjusted Incidence
Observed Incidence
0
1975
1980
1985
1990
1995
Year of Diagnosis
a
2000
2005
2010
0
1975
1980
1985
1990
1995
2000
2005
Year of Diagnosis
Source: SEER 9 areas. Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).
2010
Figure 4.4
SEER Incidence and US Death Ratesa

Cancer of the Female Breast
Joinpoint Analyses for Whites and Blacks from 1975-2010
and for Asian/Pacific Islanders, American Indians/Alaska Natives and Hispanics from 1992-2010
Incidence
150
Mortality
Rate per 100,000
150
Rate per 100,000
White
Black
125
API b
125
AI/AN c
Hispanic d
100
b
c
d
100
75
75
50
50
25
25
0
1975 1980 1985 1990 1995 2000 2005 2010
0
1975 1980 1985 1990 1995 2000 2005 2010
Year of Diagnosis
Year of Death
Source: Incidence data for whites and blacks are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta).
Incidence data for Asian/Pacific Islanders, American Indians/Alaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas, San Jose-Monterey,
Los Angeles, Alaska Native Registry and Rural Georgia). Mortality data are from US Mortality Files, National Center for Health Statistics, CDC.
Regression lines are calculated using the Joinpoint Regression Program Version 4.0.3, April 2013, National Cancer Institute. Joinpoint analyses for Whites and
Blacks during the 1975-2010 period allow a maximum of 5 joinpoints. Analyses for other ethnic groups during the period 1992-2010 allow a maximum of 3 joinpoints.
API = Asian/Pacific Islander.
AI/AN = American Indian/Alaska Native. Rates for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.
Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics are based on
NHIA and exclude cases from the Alaska Native Registry. Mortality data for Hispanics exclude cases from Connecticut, the District of Columbia, Maine,
Maryland, Minnesota, New Hampshire, New York, North Dakota, South Carolina, Oklahoma, and Vermont.
Figure 4.5
Cancer of Female Breast, Incidence Rates, 1975-2010

In Situ
situ vs Malignant, by Age
All Races, Females
500
Rate per 100,000 (linear scale)
1000
Rate per 100,000 (log scale)
.In Situ: Ages 20-49

Malig: Ages 20-49
.In Situ: Ages 50+
Malig: Ages 50+
400
100
300
200
10
100
0
1975
1980
1985
1990
1995
2000
Year of Diagnosis
2005
2010
1
1975
1980
1985
1990
1995
2000
Year of Diagnosis
Source: SEER 9 areas. Rates are per 100,000 and age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).
2005
2010
Figure 4.6

In Situ
White, Females
500
1000

Malig: Ages 20-49
.In Situ: Ages 50+
Malig: Ages 50+
400
100
300
200
10
100
0
1975
1980
1985
1990
1995
2000
Year of Diagnosis
2005
2010
1
1975
1980
1985
1990
1995
2000
Year of Diagnosis
2005
2010
Figure 4.7

In Situ
Black, Females
500
1000

Malig: Ages 20-49
.In Situ: Ages 50+
Malig: Ages 50+
400
100
300
200
10
100
0
1975
1980
1985
1990
1995
2000
Year of Diagnosis
2005
2010
1
1975
1980
1985
1990
1995
2000
Year of Diagnosis
2005
2010
Figure 4.8
Cancer of the Breast

Delay-Adjusted SEER Incidence & US Mortality
White Females vs Black Females
1975-2010
160
Rate per 100,000
Delay-Adjusted SEER Incidence

140
120
100
Delay-Adjusted SEER Incidence, White
Delay-Adjusted SEER Incidence, Black
80
US Mortality, White
US Mortality, Black
60
40
US Mortality
20
0
1975
1980
1985
1990
1995
2000
2005
2010
Regression lines are calculated using the Joinpoint Regression Program Version 4.0.3, April 2013,
National Cancer Institute.
Figure 4.9
US Death Rates for Cancer of the Breast and

Cancer of the Lung and Bronchus
White Females vs Black Females
1975-2010
50
Rate per 100,000
40
30
20
Lung & Bronchus, White
10
Lung & Bronchus, Black

Breast, White
Breast, Black
0
1975
1980
1985
1990
1995
Year of Death
2000
2005
2010
Source: US Mortality Files, National Center for Health Statistics, CDC.

Regression lines are calculated using the Joinpoint Regression Program Version 4.0.3, April 2013,
National Cancer Institute.
Figure 4.10
SEER Observed Incidence and SEER Delay Adjusted Incidence Rates a

SEER 9 Areas Compared to SEER 13 Areas
Cancer of the Female Breast, by Race
All Races
175
White
Rate per 100,000
175
Black
Rate per 100,000
SEER 9 APCs
Delay Adj, 2004-10 = 0.2
Observed, 2004-10 = 0.1
175
SEER 9 APCs
Delay Adj, 2004-10 = 0.1
Observed, 2004-10 = -0.1
SEER 9 APCs
Delay Adj, 1992-10 = 0.1
Observed, 1992-10 = 0.1
150
150
150
125
125
125
100
100
100
SEER 13 APCs
Delay Adj, 2004-10 = 0.2
Observed, 2004-10 = 0.1
75
50
1975
1990
2000
Year of Diagnosis
SEER 9 Delay-Adj. Incidence
a
Rate per 100,000
75
SEER 13 APCs
Delay Adj, 2004-10 = 0.1
Observed, 2004-10 = -0.1
75
SEER 13 APCs
Delay Adj, 1992-10 = 0.2*
Observed, 1992-10 = 0.1
2010
50
1975
1990
2000
2010
50
1975
Year of Diagnosis
SEER 9 Observed Incidence
SEER 13 Delay-Adj. Incidence
1990
2000
2010
Year of Diagnosis
SEER 13 Observed Incidence
Source: SEER 9 areas and SEER 13 areas.

Figure 4.11
Cancer of the Female Breast

5-Year SEER Conditional Relative Survival and
95% Confidence Intervals
Probabilty of surviving the next 5 years given the cohort
has already survived 0, 1, or 3 years
1998-2009 by stage at diagnosis
Survival Time Since Diagnosis
0 year (at diagnosis)
100
1 year
3 years
Percent Surviving Next 5 Years
80
60
40
20
Localized
Regional
Distant
Unstaged
Stage at Diagnosis
Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta,
San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA,
Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG). California excluding SF/SJM/LA, Kentucky,
Louisiana, New Jersey and Georgia excluding ATL/RG contribute cases for diagnosis years 2000-2009.
The remaining 13 SEER Areas contribute cases for the entire period 1998-2009.
Percent surviving is not shown if based on less than 25 cases.
Confidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error.

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SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

SEER 9 Observed Incidence , 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

U.S. Cancer Mortalityc, 1992-2010

National Cancer Institute

SEER 13 Observed Incidenceb, 1992-2010

SEER Cancer Statistics Review 1975-2010

SEER 9 Observed Incidencea, 1975-2010

SEER 13 Observed Incidenceb, 1992-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

All ages (IARC world std)c

Age-Specific Rates, 2006-2010

All ages (IARC world std)c

National Cancer Institute

Age-Specific Rates, 2006-2010

SEER Cancer Statistics Review 1975-2010

SEER Incidencea Rates, Age-Adjusted and Age-Specific Rates, by Race

Age-Specific Rates, 2006-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

5-Year Relative Survival (Percent)

5-Year Period Survival (Percent)cd

Stage Distribution (%) 2003-2009

5-Year Relative Survival (Percent), 2003-2009c

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

Devcan 6.7.0, June 2013, National Cancer Institute (http://surveillance.cancer.gov/devcan/).

Amer Ind/Alaska Natf

Amer Ind/Alaska Nat

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

Amer Ind/Alaska Natf

SEER Cancer Statistics Review 1975-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

SEER Incidence Ratesa, 2006-2010

National Cancer Institute

SEER Cancer Statistics Review 1975-2010

SEER Death Ratesa, 2006-2010