Lessons and Curriculum Part Two UnderGraduate Level Lesson I. Human Behavior and Immunology A.

The Human Behavior course examines the basic science of human behavior that is relevant to the understanding of disorders and how the body reacts to specifics diseases. Course content is coordinated with small group sessions in the Academic Colleges, allowing students to practice clinical interview and examination skills, reflect on how patients and physicians react to illness, and recognize salient aspects of the physicians professional roles. 1. Chapter 7 pgs. 89-105. "The Body's Battleground" a) Discuss how the body reacts to cuts, burns, and other types of injuries. b) Students will learn how to heal specific types of injuries. c) Discuss how the body reacts to the collapse of specific organs, and blood vessels. B. The Fundamentals of Immunology course introduces the components of the immune system, their locations in the human body, and their interactions in different clinical contexts. Students learn how the immune system senses and attempts to eliminate pathogens, and how selected pathogens evade it to cause disease. First, the genes and molecules that play key roles in the immune system including antigens, antigen receptors, antibodies, complement, major histocompatability complex loci, chemokines, and cytokines are introduced. The interactions between innate and acquired are then discussed. Finally, medically relevant forms of immune dysregulation and intervention are explored, including vaccines, immunomodulators, hypersensitivities, immunodeficiencies, autoimmunity, graft-versus-host disease, transplantation immunology, and tumor immunology. 2. Chapter 9 pgs. 117-125. "The Creeps" d) Discuss how specific pathogens enter the body and take over the immune systems. e) Discuss species genes. f) Students should learn how to administer drugs to patients through specific muscle layers i.e. epidermis, dermis II. Paper C. Study will be expected to write a 10 page paper ON EACH TOPIC as well as an 5 page personal evaluation on your opinion of EACH TOPIC on TWO of the following topics. Therefore there each student should turn in 30 pages. APA format, 10 works citied, plus an annotated bib for EACH TOPIC. 3. Innate Immune Response in Malaria 4. Immune checkpoint blockade: A new paradigm for cancer therapy 5. Innate control of metabolism and tissue regeneration 6. Engineering T cells to overcome tolerance 7. Antiviral immunity: cell autonomous sensing and effector mechanisms 8. Insights into the immunity to tuberculosis from the zebrafish III. Exam D. Exam part 1 9. Student will be evaluated in their ability to recognize specific burns chemical, fire, etc and their classifications first, second, or third on a body. Student will also have to write a patient information chart on what specific medicines would have been given to the patient. The student will also be evaluated on their ability to clean burns, as well as other injuries cuts, gunshot wounds, bacterial infections, etc. E. Exam part 2

10. Student will be expected to answer questions on the following topics: g) How is the body affected by pathogens what happens to each bodily tissue depending on what pathogen is released into the body? h) Organ transplants why does the body reject some organs? i) The makeup of a virus as well as bacteria. What is the difference and how do they affect the body differently? j) Describe the relationship of the immune system to organ transplants and the use of immunosuppressant drugs to prevent the reject of a transplanted organ. k) Immune systems response to chicken poxes, the shingles, and mad cow disease. l) How are bodily enzymes affected by pathogens?