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Rattus norvegicus
Mouse
Mus musculus
Fruit Fly
Drosophila melanogaster
Zebrafish
Danio rerio
Yeast
Saccharomyces cerevisiae
Bread Mold
Neurospora crassa
Mustard Plant
Arabidopsis thaliana
Amoeba
Dictyostelium discoideum
Roundworm
Caenorhabditis elegans
Bacterium
Escherichia coli
Living Laboratories
Like most people, you probably think of fruit flies as kitchen nuisances. But did you know that scientists use these organisms for medical research?
Fruit flies and other model organisms as different as mice, plants, and zebrafish permit scientists to investigate questions that would not be possible to study in any other way. These living systems are, relatively speaking, simple, inexpensive, and easy to work with.
Model organisms are indispensable to science because creatures that appear very different from us and from each other actually have a lot in common when it comes to body chemistry. Even organisms that dont have a body mold and yeast, for example can give scientists clues to the workings of the tissues and organs of people. This is because all living things process the nutrients they consume into the same chemicals, more or less. The genes for the enzymes involved in metabolism are similar in all organisms. The back of this poster shows a sampling of the wide variety of living laboratories that scientists are using to advance human health.
Living Laboratories
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Dictyostelium discoideum: Amoeba
This microscopic amoeba100,000 of them form a mound as big as a grain of sandis an important tool for health studies. Scientists have determined that
who study cell division, movement, and various aspects of organ and tissue development.
REX L. CHISHOLM
cells do. For that reason, plants are good models for genetic diseases that affect cell communication.
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MONTE WESTERFIELD
including birth defects and the proper development of blood, the heart, and the inner ear.
What Is NIGMS?
The National Institute of General Medical Sciences (NIGMS) supports basic biomedical research on genes, proteins, and cells. It also funds studies on fundamental processes such as how cells communicate, how our bodies use energy, and how we respond to medicines. The results of this research increase our understanding of life and lay the foundation for advances in the diagnosis, treatment, and prevention of disease. The Institutes research training programs produce the next generation of biomedical scientists, and NIGMS has programs to encourage minorities underrepresented in biomedical and behavioral science to pursue research careers.
This poster is derived from the NIGMS publication The New Genetics. To order a free copy, visit http://www.nigms.nih.gov/publications/classroom.htm