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Distinguish between genotype and phenotype and give an example of both. 3. If A is dominant to A, what are the written genotypes of AA !. Aa "hat are homologous chromosomes# aa
$. "hat are the genotypic and phenotypic ratios of a monohybrid cross %both parents are hetero&ygous for a single trait' (enotypic )atio *henotypic )atio +. Define each one of the following ,endelian principles of genetics -aw of Dominance -aw of .egregation of alleles -aw of Independent assortment /. "hat is meant by the 0*1 generation# 2he 31 generation# 2he 32 generation# 4. 5ow does a genetic disease affect a patient who inherits it from the gene to protein level# 6. Describe each pattern of inheritance and provide an example for each 7omplete dominance Incomplete dominance 7o8dominance (enes with multiple alleles *olygenic inheritance .ex 9 lin:ed inheritance .ex8influenced inheritance 1;. Distinguish between an autosomal dominant trait and an autosomal recessive and give a real life example of each. 11. Distinguish between sex lin:ed recessive and sex lin:ed dominant inheritance. 12. "hich sex is more li:ely to inherit a sex lin:ed recessive trait# "hy# 13. <lood 2ype "hat are all the patterns of inheritance blood types %including the A,<,= and the )5'# 7omplete the following table regarding blood type
Blood Type
1!. Describe the basics of the following common human genetic disorders Down syndrome 5untington>s disease 7ystic 3ibrosis .ic:le 7ell Anemia 5emophilia 7olor <lindness <aldness 1$. 7hoose any one of ,endel>s pea plant traits. .how a single trait cross of the 0*1 generation
1+. ?sing the same trait you used in @1$, cross 2 individuals of the 31 generation from the problem above.
1/. "hat are all the possible phenotypes of the 32 generation from @1+# "hat are all the possible genotypes# "hat
14. In )eebops two eyes is dominant to having only one %A and e respectively'. ,yopia %poor eyesight' is sex lin:ed recessive disorder carried on the B chromosome. %use , and m'. =nce upon a time there was a female )eebop who had two eyes and didn>t have myopia while her father had one eye and myopia. .he married a male )eebop who also had myopia and two eyes and a mother with one eye, what is the probability of them having a two 9 eyed boy with myopia# %show wor:'
"hat are the genotypes of the male and female )eebop# "hat is the genotype of the female>s father# "hat are two possible genotypes for the male>s mother# 16. Is "idow>s pea: dominant or recessive# .ee the pedigree to the right
Fig. 14-15b
Ww
ww
ww
Ww
2nd generation (parents, aunts, and uncles) 3rd generation (two sisters)
Ww ww ww Ww
Ww
ww
WW or Ww
ww
Widows peak
No widows peak
2;. 2he pedigree to the right traces the inheritance of al:aptonuria, a recessively inherited genetic disorder. Affected individuals, indicated by colored circles and sCuares, are unable to metaboli&e a substance called, al:apton, which colors the urine and stains the body tissues. 3ill in the genotype or genotypes for each family member. 5int 3 of the individuals have two possible genotypes. ?se A and a to represent the dominant and recessive alleles. (eorge DDDDDDDDDD ArleneDDDDDDDDDD .andraDDDDDDDDD 2omDDDDDDDDDD .amDDDDDDDDDD "ilma DDDDDDDDDD AnnDDDDDDDDDD ,ichaelDDDDDDDDDD DanielDDDDDDDDDD AlanDDDDDDDDDD 2inaDDDDDDDDDD 7hristopherDDDDDDDDDD
Fig. 14-UN5
George
"rlene
andra
!om
am
Wilma
"nn %arla
#ic$ael
&aniel
"lan
!ina
%$ristop$er