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The antacid action Chloride loss due to Hyperacidity, severe Rebound 1.hypertonic
is due to vomiting or from diarrhea, alkalization hyperacidity, milk, solutions must be
Generic Name: Alkalinizing neutralization of continous GI of the urine to treat alkali syndrome, administered by
agent, HCL by forming
Sodium suction. With drug toxicity, hypercalcemia, trained personel.
Antacid, NaCl and Co2.
Bicarbonate Provides temporary diuretics known to treatment of acute metabolic alkalosis,
Electrolyte 2.deteremind IV
relief of peptic produce a mild to moderate tetany, diminished
dose by arterial
ulcer pain and of hypochloremic metabolic acidosis breathing, renal
blood ph,
Brand name: discomfort alkalosis. Metabolic due to shock severe dysfunction, systemic
associated with and respiratory dehydration, anoxia, alkalosis after 3.administer
Arm and indigestion. alkalosis. uncontrolled diabetes, prolonged use, isotonic solutions
Hammer Pure Although widely
Hypocalcemia in renal disease, cardiac hypernatremia, lowly
Baking Soda used by the public,
sodiumbicarbonate which alkalosis may arrest, extracorporeal alkalosis,
4.note reasons for
is rarely prescribed cause tetany. HPN, circulation of blood, hyperirritability, fluid
therapy, any history
as antacid because convulsions, CHF, severe primary lactic or solute overload
Route of of its high of renal impairment
and other situations acidosis, prophylaxis
Administration: sodiumcontent, or CHF
where of renal calculi in
short duration of administration of gout, during
PO, IV 5.assess for edema,
action, and ability
sodium can be sulfonamide therapy which may indicate
to cause alkalosis.
Is also a systemic dangerous. As a to prevent renal inability to utilize
Dosage: and urinary systemic alkalinizer calculi and sodium bicarbonate
alkalinizer by when used as a nephrotoxicity,
½ tsp in glass increasing plasma neutralizing additive neutralizing solution 6. record input and
of water q 2 hr and urinary solution. As an to decrease chemical output
bicarbonate, antidote for strong phlebitis and client
respectively 7. do not exceed a
mineral acids bec. discomfort due to rate of
0.325-2 grams CO2 is formed, vein irritation at or administration of 8
1-4 times per which may cause near the site of Meq/kg/day in
day discomfort and even infusion of IV acid infants with cardiac
perforation. solutions. arrest to guard
against
hypernatremia
5-30 mg oral
Drug General Mechanism of Contraindications Indications Side Effects Nursing
Action action Responsibilities
Do not dissolve Hypersensitivity. Treatment & Hemorrhage, local 1.do not administer
previously formed Severe prophylaxis of irritation, erythema, IM
Generic Name: Anticoagulant clots bu they do mild pain, hematoma
thrombocytopenia. thromboembolic
forestall their or ulceration. 2. administer by deep
Heparin NA disorders.
enlargement and Generalized SC through the Z-
prevent new clots hypersensitivity, track method
from forming. It chills, fever,
Brand Name: potentiates the urticaria, asthma, 3. do not massage
inhibitory action of rhinitis, lacrimation site
Britton antithrombin ill on & anaphylactoid
Heparin Na® various coagulation reactions. 4. may be diluted in
[vial] factors including Osteoporosis, dextrose
factors IIa, IXa, Xa, aldosterone synthesis
Xia and XIIa. This suppression, delayed 5. note reasons for
occurs due to the transient alopecia, & therapy. Identify any
Route of formation of a priapism & rebound bleeding incidents
administration: complex with hyperlipidemia on
antithrombin III discontinuation. 6. perform test dose
SC, IV
and causing a 1000 units SC on
conformational clients with multiple
change in the allergies or asthma
Dosage: antighrombin III history
molecule, inhibiton
IV inj 5,000 u of factor Xa tesults 3. review drug profile
followed by SC in interference with to ensure one interact
conc soln thrombin unfavorably
10,000-20,000 generation thus the
action of thrombin otherwise anticipate
u heparin dosage
in coagulation is
inhibited. adjustment
4. assess for defects
in clotting
mechanism or any
capillary fragility:
obtain baseline
coagulation values.
Omeprazole is Lactation, use as Conditions where Headache, diarrhea 1.efficacy for more
rapidly but variably maintenance therapy inhibition of gastric and skin rashes; they than 8 weeks has not
Generic Name: Proton pump absorbed following for duodenal ulcer acid secretion may have sometimes been been determined.
inhibitor oral administration.
Omeprazole disease. OTC use in be beneficial severe enough to However, if a client
It is acid-labile and
pharmacokinetics those who have including aspiration require does not respond to 8
may vary between trouble or pain syndromes, discontinuation of weeks of therapy, an
Brand Name: the various swallowing food, dyspepsia, GERD, treatment. Other additional 4 weeks
formulations are vomiting blood peptic ulcer disease, effects rarely include may help.
Acifre® [cap developed to or excreting bloody Zollinger-Ellison athralgia and
improve oral 2. consider dosage
or black stools syndrome. myalgia, paresthesia,
bioavailability. The adjustment in those
aggression, blurred
Route of absorption of with impaired hepatic
omeprazole also vision, taste,
administration: function especially
appears to be dose- disturbance,
when used for
Oral dependent. peripheral edema,
maintaining clients
Increasing the hyponatremia, blood
dosage >40 mg has with erosive
disorders including
been reported to esophagitis.
Dosage: agranulocytosis,
increase the plasma
leucopenia and 3. can repeat OTC
concentration in a
non-linear fashion thrombocytopenia, therapy once ever 4
10-20 mg daily because of interstitial nephritis months
for 2-4 wk saturable first and hepatotoxicity.
hepatic metabolism. 4. store capsules and
powder for oral
suspension packets in
a tight container
protected from light
and moisture.
Drug General Mechanism of Contraindications Indications Side Effects Nursing
Action action Responsibilities
Bronchodilator. Patients with a Treatment of acute A small increase in 1. Note reasons for
history of severe asthma and in heart rate may occur therapy, signs
Generic Name: Anti-asthma Salbutamol is a β-
hypersensitivity to routine management in patients who and symptoms
Salbutamol adrenergic any of the of chronic inhale a large dosage indicating the
sulfate stimulant which has components of bronchospasm of salbutamol. This is need for therapy
a highly selective Aero-Vent. unresponsive to not usually 2. Monitor vital
conventional accompanied by any signs
action on the
Brand Name: therapy. changes in the 3. Review drugs
receptors in electrocardiogram. that interact with
Aero-Vent bronchial muscle Other side effects the nebule
and in therapeutic which occur with 4. Assess for any
doses, it has little or very high doses of allergies
Route of salbutamol by regarding the
Administration: no action on the
inhalation are content of the
cardiac receptors. peripheral drug
nasal,
parenteral vasodilatation and
the fine tremor of
skeletal muscle.
Dosage:
2.5-5 mg. May
repeat qid by
nebuliser.
Delivery of
aerosol may be
by face mask of
"T" piece. Use
undiluted. For
prolonged
delivery time,
dilute w/ sterile
water or normal
saline for inj.
Shortens the Hypersensitivity to Acute ventricular N&V, nervousness, 1.list reasons for
refractory period amide-type local arrhythmia. anxiety, dizziness, therapy, any
Generic Name: Anti- and suppresses the anesthetics. Stokes- Ineffective against drowsiness, sensation hypersensitivity to
arrhythmic automaticity of
Lidocaine adams syndrome, atrial arrhythmias. of heat or cold amide-type local
ectopic foci without
Hydochloride affecting wolff-parkinson numbness, injection anesthetics
conduction of white syndrome, site pain, malignant
2. those with hepatic
impulses through severe SA, Av, or hyperthermia,
or renal disease or
Brand Name: cardiac tissue. intraventricular euphoria, light-
Increases the who weigh less than
block headedness,
Cathejel eldctrical 45.5 kg will need to
nervousness, anxiety,
stimulation be watched closely
drowsiness,
threshold of the for adverse side
ventricle during confusion, changes in
Route of effects; adjust dosage
diastole. It doesn’t mood
administration: as directed.
affect BP, CO, or
IV, IM myocardial 3. Note CNS status.
contractility. Since Report sudden
lidocaine has little changes in mental
effect on
Dosage: conduction at status, dizziness
normal visual disturbances
50-100 mg at a antiarrhythmic doses, twitching, tremors,
rate of 25-50 use in acute situations may precede
mg/min (instead of convulsions
procainamide) in
instances in w/c heart 4. view monitor
block might occur
strips for myocardial
depression, variations
of rhythm
5. IM use may
increase CPR level