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by ejl212812, Sep. 2009 Subjects: heme-onc

PCOM Hematology Slides 2009 Cardiology and Hematology Slides Hematology/Oncology hematology/oncology Hematology and Oncology Pharm CARD RANGE TO STUDY Hematology/Oncology UW 1 Step II- B2, Hematology/Onc through Hematology/Oncology -- Leukemia Micro 2420 Lab Practical prepared slides Clinical Hematology Intro to hematolo... Hematology Nursing 211: Hematology exam 13 - Heme51,52,53 - advances in ... Veterinary Hematology Blood and Lymph- Hematology by Turnicky PreMed - MedLabTech 3. - Hematology 1st AID USMLE Step 1 hematology Anatomy 34

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A myeloblast is a large cell, 12-20 microns in diameter, with a nucleus that takes up most of the cell. Nuclear chromatin is fine, with little condensation and fairly homogenous in appearance. Nucleoli may vary in number and are apt to be large. The scanty cytoplasm is blue without granules.

What is the large cell?

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A promyelocyte may be the same size as the myeloblast or even larger. Unlike the myeloblast, the promyelocyte's cytoplasm contains large black or purple granules. Nucleoli may be present.

What is this cell?

The myelocyte is smaller than the myeloblast or the promyelocyte. Unlike the myeloblast and promyelocyte, the myelocyte's cytoplasm contains specific granules, i.e. brick-red (eosinophils), large, blue-black granules (basophils), and lilac granules (neutrophils). The nucleus still has a round or oval shape and no nucleoli are present. Myelocytes are not seen on a normal peripheral blood smear.

What is this cell?

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Metamyelocytes (Juvenile) are smaller than the myelocytes. There is more marked clumping of the nuclear chromatin so that the nucleus becomes much denser, takes up less than half the cell volume, and is indented (kidney-shaped).

What is this cell?

The band (stab) is similar to the metamyelocyte but the band is smaller and has a horseshoe-shaped nucleus. The cytoplasm may contain fine lilac granules (neutrophilic), brick-red granules (eosinophilic) or large blue-black granules (basophilic). Bands normally account for 0-5% of the total leukocyte count in circulating blood of the adult.

What is this cell?

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Metamyelocytes (Juvenile) are smaller than the myelocytes. There is more marked clumping of the nuclear chromatin so that the nucleus becomes much denser, takes up less than half the cell volume, and is indented (kidney-shaped).

What is this cell?

The band (stab) is similar to the metamyelocyte but the band is smaller and has a horseshoe-shaped nucleus. The cytoplasm may contain fine lilac granules (neutrophilic), brick-red granules (eosinophilic) or large blue-black granules (basophilic). Bands normally account for 0-5% of the total leukocyte count in circulating blood of the adult.

What is this cell?

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A segmented neutrophil (poly) is approximately 12-14 microns in diameter. This is the final stage of granulocytic development. Normal polys generally have two to five lobes. Hypersegmented polys, containing six or more lobes, are characteristically seen in megaloblastic anemias. Polys normally account for 45-75% of a normal differential in an adult. What is this cell?

A monocyte has blue-gray cytoplasm and a lobulated nucleus. It's distinguished from other leukocytes by the folding-over of the nuclear lobe (fetal-shaped). 4-11% in a normal blood differential.

What is this cell?

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Basophils are present in small numbers (0-3%) in a normal blood smear. Dark coarse granules and indistinct nucleus are characteristic. The basophil is a source of histamine and involved with allergic and inflammatory/immune responses. Increased numbers are seen in myeloproliferative disorders, e.g. chronic myelogenous leukemia and polycythemia vera. What is this cell?

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