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Action Principal intracellular cation; essential for maintenance of intracellular isotonicity, transmission of nerve impulses, contraction of cardiac, skeletal, and smooth muscles, maintenance of normal kidney function, and for enzyme activity. Plays a prominent role in both formation and correction of imbalances
Indication To prevent and treat potassium deficit secondary to diuretic or corticosteroid therapy. Also indicated when potassium is depleted by severe vomiting, diarrhea; intestinal drainage, fistulas, or malabsorption; prolonged diuresis, diabetic acidosis. Effective in the treatment of hypokalemic alkalosis (chloride, not the gluconate).
Contraindication Adverse Effects Severe renal GI:Nausea, impairment; vomiting, severe hemolytic diarrhea, reactions; abdominal untreated distension. Addisons disease; crush syndrome; BodyWhol early postoperative e:Pain, oliguria (except mental during GI confusion, drainage); irritability, adynamic ileus; listlessnes acute dehydration; s, heat cramps, paresthesi hyperkalemia, as of patients receiving extremities potassium-sparing , muscle diuretics, digitalis weakness intoxication with and AV conduction heaviness disturbance. of limbs, difficulty in swallowing , flaccid paralysis. Urogenital: Oliguria, anuria.
Nursing Considerations -Monitor I&O ratio and pattern in patients receiving the parenteral drug. If oliguria occurs, stop infusion prompytly and notify physician. Monitor for and report signs of GI ulceration (esophageal or epigastric pain or hematemesis). Monitor patients receiving parenteral potassium closely with cardiac monitor. Irregular heartbeat is usually the earliest clinical indication of hyperkalemia. Be alert for potassium intoxication may result from any therapeutic dosage, and the patient may be asymptomatic.
in acidbase metabolism.
Hematologi c:Hyperkal emia. Respirator y:Respirato ry distress. CV:Hypote nsion, bradycardi a; cardiac depression , arrhythmia s, or arrest; altered sensitivity to digitalis glycosides. Severe allergic reactions s uch as rash, hives, itching, dyspnea, tightness in
Anti-fibrinolytic, synthetic antihemorrhagi derivative of c the amino acid lysine. It exerts its antifibrinolyti c effect through the reversible
Management of hemophilic patients (those having Factor VIII or Factor IX deficiency) who have oral mucosal bleeding, or are undergoing tooth
Allergic reaction to the drug or hypersensiti vity Presence of blood clots (eg, in the leg, lung,
Unusual change in bleeding pattern should be immediately reported to the physician. For women who are taking Tranexamic acid to control
extraction or other oral surgical procedures. Medical: epistaxis, hemoptysis, hematuria, peptic ulcer with hemorrhage and blood dyscrasias with hemorrhage
eye, brain), have a history of blood clots, or are at risk for blood clots Current administrati on of factor IX complex concentrate s or antiinhibitor coagulant concentrate s
the chest, swelling of the mouth, face, lips or tongue Calf pain, swelling or tenderness Chest pain Confusion Coughing up blood Decreased urination Severe or persistent headache Severe or persistent body malaise Shortness of breath Slurred speech Slurred speech Vision changes
heavy bleeding, the medication should only be taken during the menstrual period. Tranexamic Acid should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed. The medication can be taken with or without meals. Swallow Tranexami c Acid whole with plenty of liquids. Do not break, crush, or chew before swallowing.
Dopamine antagonist that acts by increasing receptor sensitivity and response of upper GIT tissues to acetylcholin e.
Gastrointestinal motility, nausea, vomiting of central and peripheral origin assoc. with surgery.
Give 30 mins before meals and at bed time Assess mental status during treatment Tell patient to avoid driving and other hazardous activities for at least 2 hrs. Advice patient to avoid alcohol and other CNS depressant that enhance sedating properties of this drug. Assess patient for abdominal pain. Note presence of blood in emesis, stool, or gastric aspirate Ranitidine may be added to total parenteral nutrition
Anti-ulcer
Completely inhibits action of histamine on the H2 at receptor sites of parietal cells, decreasing
Duodenal and gastric ulcers Maintenance therapy for gastric and duodenal ulcer
Contraindicated in patients hypersensitive to drug and those with porphyria Use cautiously in patients with hepatic dysfunction. Adjust
Vertigo, malaise, headache, blurred vision, jaundice, burning and itching at injection site
solution Instruct patient on proper use of OTC preparation as indicated. Remind patient to take once daily prescription drug at bed time for best results Instruct patient to take without regard to meals because absorption isnt affected by food
Antibiotic To inhibit bacterial protein synthesis at level or 3OS and 5OS bacterial ribosomes and to alter cytoplasmic membrane of susceptible organisms. To reduce the Pregnancy development of drugHypersensitivity resistant bacteria.
severe headache, dizziness, blurred vision; fever, chills, body aches, flu symptoms; severe blistering, peeling, and red skin rash; urinating less than usual or not at all; pale or yellowed skin, dark colored urine, fever, confusion or weakness; severe pain in your upper stomach
Monitor for s/s of super infection and hypersensitivity reaction. With long term use, monitor CBC, liver function tests, and bone growth Assess neurologic status, stay alert for benign intracranial hypertension.
spreading to your back, nausea and vomiting, fast heart rate; loss of appetite, jaundice (yellowing of the skin or eyes); or Easy bruising or bleeding, unusual weakness. If pt has adverse CNS reactions, such as seizures or peripheral neuropathy, tell prescriber and stop drug immediately. Monitor pt with severe liver disease because slowed metronidazole metabolism may cause drug to accumulate in
Undergoes intracellular chemical reduction during anaerobic metabolism. After metronidazole is reduced, it damages
Breast-feeding, hypersensitivity to metronidazole or its components, trichomoniasis during first trimester of pregnancy
CNS: Ataxia, dizziness, encephalopathy, fever, headache, light-headedness, peripheral neuropathy, seizures (high doses) EENT: Dry mouth,
DNAs helical structure and breaks its strands, which inhibits bacterial nucleic acid synthesis and causes cell death,
oides fragilis, Clostid ium difficile , Clostri dium perfing ens, Eubact erium, Fusob acteriu m, Peptoc occus, Peptos treptoc occus, and Veillon ella sp. To treat amebi asis (Entam oeba histolyt
lacrimation (topical form), metallic taste, pharyngitis GI: Abdominal cramps or pain, anorexia, diarrhea, nausea, pancreatitis, vomiting GU: Darkened urine, vaginal candidiasis (oral, parenteral, and topical forms); burning or irritation of sexual parteners penis, candidal cervicitis or vaginitis, dysuria, urinary frequency, vulvitis (vaginal form) HEME: Leukopenia MS: Back pain SKIN: burning sensation, stinging sensation, dry skin (topical
the body and increase the risk of adverse effects. If skin irritation occurs, apply topical gel less frequently or discontinue it, as ordered. Monitor CBC and culture and sensitivity test if therapy lasts longer than 10 days or if second course of treatment is needed Give IV drug by slow infusion over 1 hr; dont give by direct IN injection
ica) Capsul es, Tablet s Childre n. 11.6 to 16/7 mg/kg t.i.d. for 10 days
form); erythema, pruritus, rash, urticaria (oral and parenteral forms) OTHER: injection site edema, pain, or, tenderness.