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Immunisation Schedule

Age Birth

Vaccines BCG OPV zero Hepatitis B -1

Note

6 weeks

OPV-1 + IPV-1 / OPV -1 DTPw-1 / DTPa -1 Hepatitis B -2 Hib -1

OPV alone if IPV cannot be given

10 weeks

OPV-2 + IPV-2 / OPV-2 DTPw-2 / DTPa -2 Hib -2

OPV alone if IPV cannot be given

14 weeks

OPV-3 + IPV-3 / OPV -3 DTPw-3 / DTPa -3 Hepatitis B -3 Hib -3

OPV alone if IPV cannot be given

Third dose of Hepatitis B can be given at 6 months of age

9 months

Measles

15-18 months OPV-4 + IPV-B1 / OPV -4 DTPw booster -1 or DTPa booster -1 Hib booster MMR -1

OPV alone if IPV cannot be given

2 years

Typhoid

Revaccination every 3-4 years

5 years

OPV -5 DTPw booster -2 or DTPa booster -2 MMR -2 The second dose of MMR vaccine can be given at any time 8 weeks after the first dose

10 years

Tdap HPV Only girls, three doses at 0, 1-2 and 6 months

Vaccines that can be given after discussion with parents More than 6 weeks Pneumococcal conjugate 3 primary doses at 6, 10, and 14 weeks, followed by a booster at 15-18 months

More than 6 weeks

Rotaviral vaccines

(2/3 doses (depending on brand) at 4-8 weeks interval

After 15 months

Varicella

Age less than 13 years: one dose Age more than 13 years: 2 doses at 4-8 weeks interval

After 18 months

Hepatitis A

2 doses at 6-12 months interval

1. The IAP endorses the continued use of whole cell pertussis vaccine because of its proven efficacy and safety. Acellular pertussis vaccines may undoubtedly have fewer side-effects (like fever, local reactions at injection site and irritability), but this minor advantage does not justify the inordinate cost involved in the routine use of this vaccine.

2. If the mother is known to be HBsAg negative, HB vaccine can be given along with DTP at 6, 10, 14 weeks/ 6 months. If the mother's HBsAg status is not known, it is advisable to start vaccination soon after birth to prevent perinatal transmission of the disease. If the mother is HBsAg positive (and especially HBeAg positive), the baby should be given Hepatitis B Immune Globulin (HBIG) within 24 hours of birth, along with HB vaccine.

3. Varicella, Hepatitis A and Pneumococcal Conjugate vaccines should be offered only after one to one discussion with parents. Also refer to the individual vaccines notes for recommendations.

4. Combination vaccines can be used to decrease the number of pricks being given to the baby and to decrease the number of clinic visits. The manufacturer's instructions should be followed strictly whenever "mixing" vaccines in the same syringe prior to injection.

5. At present, the only typhoid vaccine available in our country is the Vi polysaccharide vaccine. Revaccination may be carried out every 3- 4 years.

6. Under special circumstances (e.g. epidemics), measles vaccine may be given earlier than 9 months followed by MMR at 12-15 months.

7. During pregnancy, the interval between the two doses of TT should be at least one month.

8. We should continue to use OPV till we achieve polio eradication in India. IPV can be used additionally for individual protection.

9. OPV must be given to children less than 5 years of age at the time of each supplementary immunisation activity.

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