Drug Name

Injection Cipro Chem name Ciprofloxacin Drug class Quinolones

Dose & Route

100 ml (200 mg) Intravenous BD

Action
Ciprofloxacin promotes breakage of double-stranded DNA in susceptible organisms and inhibits DNA gyrase, which is essential in reproduction of bacterial DNA.

Indications

Side-effects
GI disturbances; headache, tremor, confusion, convulsions; rashes; joint pain; photo toxicity. Transient increases in serum creatinine. Haematological, hepatic and renal disturbances. Vacuities, pseudomembranous colitis and tachycardia. Photo toxicity. Potentially Fatal: Anaphylactoid reaction; cardiopulmonary arrest.

Nursing Responsibilities
Special precautions should be taken for: Epilepsy, history of CNS disorders; severe renal or hepatic dysfunction; G6PD deficiency; myasthenia gravis. Caution when used in patients with QT prolongation or risk factors. Discontinue treatment if patients experience tendon pain, inflammation or rupture. May impair ability to drive or operate machinery. Safety and efficacy have not been established in pregnant and lactating women. Not to be used in children <18 yr; except where benefit clearly exceeds risk.

Cat scratch disease, Typhoid and paratyphoid fever, Urinary tract infections, Spotted fever, typhus, gastroenteritis, Anthrax, Brucellosis, Septicaemia, Absorption: Rapidly Infections in and well absorbed immune from the GI tract compromised with peak plasma patients, concentrations after Cancroid, biliary 2 hr (oral); may be tract infections, delayed by the gonorrhoea, presence of food. meningococcal meningitis.

Drug Name
Tablet Rantac Chemical nameRanitidine hydrochloride. Functional class- H2 receptor antagonist.

Dose & Route

Action

Indications
Gastric ulcers, Duodenal ulcers, hyper secretory conditions, Stress ulcer, Gastroeosophageal refluxes, Multiple endocrine syndrome, heartburn. It is also given to prevent hyper secretory condition and to prevent ulcer in stomach with other medicines during chronic therapy.

Side-effects
Headache, dizziness. Rarely hepatitis, thrombocytopaen ia, leucopaenia, hypersensitivity, confusion, gynaecomastia, impotence, somnolence, vertigo, hallucinations. Potentially Fatal: Anaphylaxis, hypersensitivity reactions.

Nursing Responsibilities
Assess gastric pH > 5 should be monitored. Assess input and output ratio. Assess creatinine and BUN ratio. Assess for mental status, anxiety, weakness, confusion and abdominal discomfort. Administer with meals for prolonged effect. Administer intravenous under aseptic techniques and follow rights of drug administration. Antacid should be given 1 hour before or after.

150 mg Ranitidine Orally inhibits the Twice a day. histamine at H2 receptor site at parietal cells which inhibits gastric acid secretion.

Drug Name
Tablet Dan-P

Dose & Route

Action

Indications
It is given in the painful inflammatory musculoskeletal conditions. Acute gout, Post-operative pain, fever, lowback pain and degenerative arthritis; joint disorders.

Side-effects

Nursing Responsibilities

500 mg Diclofenac sodium orally is non-steroidal Diclofenac twice a day anti-inflammatory sodium 50 mg drug. It inhibits the + enzyme Paracetamol cyclooxygenase in 500 mg the pathway of prostaglandin Drug classsynthesis and thus analgesic and reducing pain. antiinflammatory Paracetamol is combination analgesic and antipyretic.

The most common To assess temperature and side effects are pain frequently. nausea, vomiting and rash. To assess reasons for use and expected outcome. Prolong intake may be harmful Assess for hypersensitivity for the liver. reactions: rash, bronchospasms with some Potentially Fatal: products. Bleeding or perforation Administer round the clock through peptic to keep fever reduced and ulcer, rarely blood minimize pain. dyscrasia or anaphylaxis, acute Evaluate therapeutic renal failure. response: pain scale and reduction in temperature.