Scribd Logo
Upload

Welcome to Scribd!

  • The Design and Manufacture of Medicines: M I C H A E L E - Aultoribpharmphdfaapsfrpharms

    Uploaded by

    Leyla Majunda
    74 views3 pages
    This document provides a summary of the contents of the book "Aulton's Pharmaceutics: The Design and Manufacture of Medicines". The book is divided into 6 parts that cover scientific principles of dosage form design, particle science and powder technology, pharmaceutical microbiology and sterilization, biopharmaceutical principles of drug delivery, dosage form design and manufacture, and pharmaceutical plant design. The contents include chapters on topics such as dissolution, rheology, disperse systems, kinetics of product stability, solid-state properties, particle size analysis, granulation, drying, compaction, solutions, suspensions and emulsions, powders and granules, modified-release dosage forms, coating, capsules, and sterilization techniques

    Original Description:

    bat

    Original Title

    barne

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document provides a summary of the contents of the book "Aulton's Pharmaceutics: The Design and Manufacture of Medicines". The book is divided into 6 parts that cover scientific principles of dosage form design, particle science and powder technology, pharmaceutical microbiology and sterilization, biopharmaceutical principles of drug delivery, dosage form design and manufacture, and pharmaceutical plant design. The contents include chapters on topics such as dissolution, rheology, disperse systems, kinetics of product stability, solid-state properties, particle size analysis, granulation, drying, compaction, solutions, suspensions and emulsions, powders and granules, modified-release dosage forms, coating, capsules, and sterilization techniques

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    74 views3 pages

    The Design and Manufacture of Medicines: M I C H A E L E - Aultoribpharmphdfaapsfrpharms

    Uploaded by

    Leyla Majunda
    This document provides a summary of the contents of the book "Aulton's Pharmaceutics: The Design and Manufacture of Medicines". The book is divided into 6 parts that cover scientific principles of dosage form design, particle science and powder technology, pharmaceutical microbiology and sterilization, biopharmaceutical principles of drug delivery, dosage form design and manufacture, and pharmaceutical plant design. The contents include chapters on topics such as dissolution, rheology, disperse systems, kinetics of product stability, solid-state properties, particle size analysis, granulation, drying, compaction, solutions, suspensions and emulsions, powders and granules, modified-release dosage forms, coating, capsules, and sterilization techniques

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 3

    Aulton's Pharmaceutics

    The Design and Manufacture of Medicines


    Edited by

    M i c h a e l E . AultOriBPharmPhDFAAPSFRPharmS

    THIRD EDITION

    CHURCHILL LIVINGSTONE

    11 si \ 1 1
    EDINBURGH LONDON NEW YORK OXFORD PHILADELPHIA ST LOUIS SYDNEY TORONTO 2007

    Contents

    What is "pharmaceutics'? 1 Design of dosage forms 4

    12 13

    Mixing 152
    \ \ t I n It, l u l l

    Powder flow 168


    ./ \ Sldiutuitli M I Aultmi

    PART1 Scientific principles of dosage form design 15 2 3 4 5 6 7 Dissolution and solubility 16


    \l I Aitllnn

    PART 3 Pharmaceutical microbiology and sterilization 181 14 15 Fundamentals of microbiology 182


    (,. H. lUtnlun

    Properties of solutions 33
    U / \ultun

    Rheology 42
    < MdHIUtt

    Pharmaceutical applications of microbiological techniques 205


    .\ A Hu,l^rs

    Surface and interracial phenomena 59 ./. / I'll Disperse systems 70


    /). Atlwmul

    16

    Action of physical and chemical agents on microorganisms 225


    (, \\ llunlun. \ .\. //..,/!.<*

    17 18

    Principles of sterilization 242 V A. Wuhh. ./>: Maillanl Sterilization in practice 251


    ./>. MailUinl. S. I, Wdhh

    Kinetics of product stability 99

    PART 2 Particle science and powder technology 109 8 9 10 Solid-state properties 1 0 1


    (/, Bin ktun

    PART 4 Biopharmaceutical principles of drug delivery 265 19 20 Introduction to biopharmaceutics 266


    M. Ashlunl

    Particle size analysis 121


    ./. ,V Stdiiitorth. M. /.. Altitun

    Particle size reduction 137


    ./. ,V. Stdiiifurth, M. E. Altitun

    Gastrointestinal tract - physiology and drug absorption 270 M. Ashfoni Bioavailability - physicochemical and dosage form factors 286 M. Ashfoni

    21

    11 Particle size separation 145 ./. N. Staniforth. M. E. Aulton

    CONTENTS

    22

    Assessment of biopharmaceutical properties 304

    34

    Hard gelatin capsules II /.'. Junes

    515

    M. Ashtonl 35 23 Dosage regimens ./. //. (ulleti 324 36 Soft gelatin capsules 527 K. (i. Hutchison, J. lerdiiidinlu Pulmonary drug delivery A. M (i. Taylor Nasal drug delivery /' M Idxlur 555 539

    PART 5 Dosage form design and manufacture 335


    24 Pharmaceutical preformulation
    ./. /. Wells. M /;. Altitun

    37

    38 336 39 25 26 27 Solutions 361 M. K. Billanv 40 Clarification 374 A. M. Iw it, hell 41 Suspensions and emulsions M. R HilldiiY Powders and granules M I' Summers 406 43 29 Granulation 410 M. I' Summers, M. E. Aiilton Drying 425 M. /.. Aultnn Tablets and compaction (/'. Alderhuni 441 44 383 42 28

    Transdermal drug delivery B. W. Barrx Wound dressings (7. M. Ea lestun 598

    565

    Rectal and vaginal drug delivery ./. ./. Tukker

    606

    Delivery of pharmaceutical proteins 616 I). ./. A. Cruinmelln, E. van Wiiuicn. A. Mckkinti Packs and packaging /' M. Taylor 626

    Microbial contamination, spoilage and preservation of medicines 640 A'. A. HudKe\ Product stability and stability testing
    A. R. Barnes

    30 31 32

    650

    45

    Pharmaceutical plant design M. /;. Aulton, A. M. Twitehell

    666

    Modified-release peroral dosage forms 483 ./. H. Collclt. R. ('. Moreton Coating of tablets and multiparticulates 500 S. C. Porter

    46

    H e a t transfer and the properties and use

    of steam 679 /\. M. Twitehell Index 691

    33

    You might also like