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Which one of the following is a short acting glucocorticoid Long-term use of combined oral contraceptive may lead to the following EXCEPT Adverse effects of corticosteroid therapy are following EXCEPT Long term use of oral contraceptives produces following adverse reactions EXCEPT Glibenclamide is used in treatment of diabetes mellitus because Which of the following drugs is used for treatment of thyroid crisis Uses of mifepristone are following EXCEPT Mode of action of acarbose in treatment of diabetes mellitus is Which of the following drugs is an antiprogestin Following are side effects of combined oral contraceptive agents EXCEPT Tamoxifen is used for treatment of carcinoma of breast because it is Which of the following is used in treatment of endometriosis Which of the following corticosteroids is given by inhalation Which of the
Prednisolone
Hydrocortisone
Dexamethasone
Betamethasone
Hyperuricaemia
Hyperglycaemia
Hypertension
Venous thrombosis
Hypotension
Hyperglycaemia
Peptic ulcer
Muscle weakness
Hypertension
Osteoporosis
Hyperglycaemia
Venous thrombosis
Propylthiouracil
Thiocyanates
Antiprogestin
Misoprostol
Mifepristone
Gestodene
Hypotension
Weight gain
Breast tenderness
An alkylating agent
An antimetabolite
A hormone antagonist
Diethylstilbestro l
Danazol
Clomiphene
Mestranol
Hydrocortisone Hemisuccinate
Fludrocortisones
Betamethasone Dipropionate
Triamcinolone
Lente insulin
Regular insulin
Ultralente insulin
Protamine Zinc
following insulin preparations is given intravenously Which of the following is NOT TRUE regarding betamethasone Indications for the use of glucocorticoids include all the following except Which of the following is an action of sulphonylurea Following are the effects of hormone replacement therapy EXCEPT With which of the insulin preparations soluble insulin can bind and SHOULD be mixed only with regular insulin Antabuse like reaction can occur with which of the following antidiabetic drugs Mode of action of sulphonyl ureas includes all the following except Drugs causing hyperglycemia Which of the following drugs is not hypoglycemic The various insulin preparations useful in the treatment of diabetes mellitus differ primarily in Steroids
insulin
Anaphylactic shock
Addisons disease
Increases formation of insulin Reduced risk of coronary artery disease Semilente insulin
Blood sugar reduction occurs only in diabetics Suppression of symptoms of menopause Lente insulin
Metformin
Chlorpropamide
Acarbose
Glucocorticoids Tolbutamide
Focus of action
Mode of biotransformation
Steroids reduce the rate of repair of tissues thus delays the healing Neisseria meningitis
Neisseria gonorrhea
Which drug causes photosensitivity Fluconazole is used for the treatment of A patients suffering from syphilis is given pencillin. He may develop When broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may be The mechanism of action of chloramphenicol is inhibition of symthesis of Prolonged administration of streptomycin may result in damage to the A distinct advantage that tetracyclines have over penicillins is that tetracyclines Antibiotic that interferes with DNA function is The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is Stepwise mutation for drug resistance is seen with Optic neuritis is a side effect of Tetracycline is more preferred in periodontics because First line of antitubercular drug is All of the following are included in antitubercular therapy except
Cephalosporin Syphilis Jarish Herxheimer reaction Increased because of decreased renal excretion of the anticoagulant
Cell wall
Cell membrane
Protein
DNA
Optic nerve
Facial nerve
Auditory nerve
Trigeminal nerve
Metronidazole
Nystain
Tetracycline
Ampicillin
Erythromycin
Penicillin G
Methicillin sodium
Penicillin
Streptomycin
Garamycin
Kanamycin
Ethambutol Pyridoxine
Cephalosporins Metoclopramide
Penicillinase resistant penicillin is All of the following drugs are components of the MOPP cancer Chemotherpay regimen EXCEPT All of the following are bactericidal drugs against Mycobacterium tuberculosis EXCEPT One of the following is not penicillinase susceptible Nevirapine is a
Methicillin Procarbazine
Amoxycilin Vincristine
Carbenicillin Mechlorethamine
Rifampicin
Isoniazid
Pyrazinamide
Tetracycline
Amoxicillin
Penicillin G
Piperacillin
Cloxacillin
Protease inhibitor
Which of the following drug does not show renal toxicity AIDS is a disease if the immune system primarily affecting All are macrolides antibiotics except The most preffered acute emetic for emesis induced by anticancer drug is True about aminoglycoside is all except Cotrimoxazole is a combination of Trimethoprim with following sulphonamide In infections caused by staphylococci which produce betalactamase, which Penicillin is not effective Which of the following amino glycosides is used only as topical preparation
Gentamycin
Fusion inhibitor
Isoflurane
Granulocytes
Immunoglobulins
Opsonins
T lymphocytes
Erythromycin Ondensetron
Roxithromycin Metaclopromide
Neomycin Clofazimine
Calithromycin Ehthmabutol
Oxacillin
Cloxacillin
Methicillin
Amikacin
Framycetin
Tobramycin
Gentamicin
Which of the following drugs is effective only in tuberculosis and is not effective against any other organism Which antibiotic group should be avoided to be used in children because of potential risk of arthropathy Which of the following antimalarial drugs acid as an inhibitor of enzyme dihydrofolate reducatse In which of the following conditionsMetronidazole given alone is NOT effective Which of the following is applicable to Amoxycillin Which of the following statements is NOT APPLICABLE to penicillin G Which one of the following extended spectrum penicillins is effective against pseudomonas Which of the following drugs is a betalactamase inhibitor Which of the following antibacterial drug inhibits heptic cytochrome P450 drug metabolizing enzyme system and leads to clinically significant drug interaction Which one of the
Rifampicin
Isoniazid
Amikacin
Ciprofloxacin
Fluoroquinolone s
Marcrolides
Aminoglycosides
Semisynthetic penicillins
Chloroquine
Quinine
Pyrimethamine
Mefloquine
Amoebic dysentery
Amoeboma
It is acid labile
Ampicillin
Ticarcillin
Cloxacillin
Imipenem
Mecillinam
Clavulanic acid
Aztreonam
Erythromycin
Roxithromycin
Clarithromycin
Ampicillin
Zidovudine
Stavudine
Amantadine
Didanosine
following antiviral agents does not act as anti retroviral Bacterial cell wall synthesis is inhibited by all the following antibiotics EXCEPT Which of the following statement is APPLICABLE to trimethoprim Which of the following drugs can be used for treatment of urinary tract infection during pregnancy Which of the following antitubercular drugs has poor penetration into macrophages Metronidozole is NOT effective for treatment of Which of the following drugs is NOT effective in Leishmaniasis For which of the following drugs peripheral neuritis is associated as adverse effect Which of the following quinolones has broader spectrum of activity against gram positive and gram negative organisms Which of the following antiamoebic drugs is also effective in anaerobic infection Artemether is administered in adults by following route and duration schedule Which of the
Penicillin
Cephalosporins
Vancomycin
Doxycycline
Cephalosporins
Isoniazid
Pyrazinamide
Thiacetazone
Rifampicin
Aerobic infections
Trichomoniasis
Pentamidine
Suramine
Rifampicin
Isoniazid
Ethionamide
Rifabutin
Ciprofloxacin
Sparfloxacin
Nalidixic acid
Pefloxacin
Paromomycin
Metronidazole
Emetine
Chloroquine
Agranuloytosis
Thrombocytopen
Hepatotoxicity
Nephrotoxicity
following is a serious toxicity of cyclosporine Which of the following drugs can cause hyperuricaemia as adverse effect Interference with cell wall synthesis of bacteria is the mode of action of all the following antimicrobial drugs EXCEPT Which of the following antifungal agents is also effective in leishmaniasis Antibiotic combinations are indicated except Following antitubercular drugs are administered by oral route EXCEPT Mefloquine is indicated in Which of the following Cephalosporins can be given orally Which of the following Penicillins can cause bleeding as an adverse effect Zidovudine is used for treatment of HIV infection because All of the following drugs are effective for hookworm infection EXCEPT The mechanism of action of sulfonamide is Which of the following is NOT TRUE of gentamicin
ia
Rifampicin
Amikacin
Isoniazid
Ethambutol
Bacitracin
Vancomycin
Cephalosporins
Chloramphenicol
Nystatin
Amphotericin B
Hamycin
Clotrimazole
Cerebral malaria
Cefoxitin
Cloxacillin
Carbenicillin
Amoxicillin
Methicillin
Inhibition of synthesis of cell membranes It has synergistic action with Penicillin but should not be
Jarisch Herxheimer reaction is produced by Quinine is used for P. falciparum treatment because Which drug is effective for treatment of anaerobic infectious Half life of mefloquine is Enzyme dihydrofolate reducatse is inhibited by Which of the following penicillin derivatives is active against Pseudomonas aeruginosa Which of the following cephalosporins is active against Pseudomonas Which of the following adverse effects is NOT observed with aminoglycoside antibiotics Which of the following antibiotics has a chelating property Pyridoxine is used for treatment of isoniazid induced The phenomenon of antibiosis was demonstrated by Which of the following drug(s) is/are bacteriostatic Drug (s) to be avoided in liver disease is/are
Tetracycline
Penicillin
Fluoroquinolones
Clotrmazole
2 4 hours Sulfonamide
12 24 hours Rifampicin
3 6 days Trimethoprim
Methicilin
Ampicillin
Oxacillin
Ticarcillin
Cefuroxime
Cefaclor
Ceftazidime
Cefixime
Anaphylactic reaction
Renal toxicity
Ototoxicity
Chloramphenico l
Penicillin
Erythromycin
Tetracycline
Neurotoxicity
Hepatotoxicity
Arthralgia
Drug resistance
Waksman
L Pasteur
Fleming
Nalidixic acid
Cotrimoxazole
Ethambutol
Penicillin
Erythromycin estolate
Nalidixic acid
Tetracyclines
Penicillin + streptomycin
Penicillin + tetracycline
Penicillin + sulfonamide
Streptomycin + chloramphenicol
Threshold value for fast channel action potential (AP) is Which of the following 5HT receptor antagonists increases appetite and causes weight gain Which of the following drugs is used in treatment of acute migraine CNS depressant drug which produces sleep but patient may be awakened by inducing pain. This type of drug is called Common side effect associated with all NSAID drugs is Which of the following antihistaminies are effective in preventing motion sickness Mechanism of action of digitalis is/are
Least potent sympathomimeti c bronchodilator Greater than level than slow channel AP Cyproheptadine
Most potent sympathomimetic bronchoconstrictor Less negative level than slow channel AP Methysergide
Both B and C
Clozapine
Buspirone
Propranolol
Sumatriptan
Mianserin
Antileptic
Antisympathetic
Sedative
Hypnotic
Drowsiness
Gastric irritation
Xerostomia
Constipation
Cetirizine
Cyclizine
Chlorpheniramine
Astemizole
Torsades De pontes is produced as adverse effect by Drug of choice for congestive heart failure in emergency is Most of the drugs used for treatment of migraine act through Antiseptic action of
Promethazine
Digitoxin
Digoxin
Lanatoside C
Ouabain
Adrenergic receptors
Dopaminergic receptors
5HT receptors
GABA receptors
20 to 70%
70 to 90%
90 to 100%
100%
10
ethyl alcohol is maximum at which of the following concentration Which of the following is only a venodilator Which of the following is short acting Which of the following drugs has highest polarity All are true of Benzodiazepines except
Hydralzine
Minoxidil
Nifedipine
Which of the following diuretics is used in treatment of Glaucoma Quinidine is contraindicated with digoxin because
Spironolactone
Hydrochlorothiazi de
First drug of choice for ventricular tachycardia is Hypolipidemic drug acting by mechanism of bile acid binding is Promethazine is an Unfavourable effect on serum lipid profile is an adverse effect of which of the following drugs Which of the following benzodiazepines do not produce any active metabolite in the body Which one of the following antiarrhythmic drugs in therapeutic doses does not cause ECG
Lidocaine
Quinidine increases plasma concentration of digoxin. Digoxin toxicity may be precipitated Quinidine
Digoxin increases plasma concentration of quinidine. Quinidine toxicity may be precipitated Verapamil
Adenosine
Gemfibrozil
Probucol
Nicotinic acid
Cholestyramine
Antihistaminic Propranolol
Procainamide
Lignocaine
Quindine
Flecainide
11
changes Diuretics are contraindicated with digitalis because of Which of the following is a centrally acting antihypertensive agent Variant Prinzmetals angina is usually provoked by Organic nitrates in low doses cause
Emotion
Exercise
Coitus
Which of the following is an inducing agent used in general anaesthesia With which of the following drugs, abrupt withdrawal may result in rebound hypertension Methaemoglobinae mia after prolonged use of high doses can occur with which of the following antianginal drugs Chlorpromazine is a Which of the following antihypertensive drugs has mechanism of action other than inhibition or Renin Angiotensin system Which of the following drugs is used for hypertension during pregnancy Benzodiazepines have Enalapril acts as an
Nitrous oxide
Methohexitone sodium
The vasodilator effect on both types of blood vessels is not dose dependant Ketamine
Guanethidine
Clonidine
Nifedipine
Atenolol
Organic nitrates
Diltiazem
Nifedipine
Propranolol
Barbiturate Enalapril
Phenothiazine Ramipril
ACE inhibitors
Labetaolol
Hydrochlorothiazide
12
antihypertensive agent because Mechanism/s of action of GTN (glyceryl trinitrate) in variant angina is/are Which of the following methyl xanthenes is used in CNS stimulation Which one of the following is not an endogenous opioid peptide Which of the following Benzodiazepines has longest elimination half-life Mechanism of action of sodium valproate is
channel blocker Through dilator effect on larger coronary vessels Caffeine Through reduction of cardiac work Theophylline
Theobromine
Beta endorphin
Enkephalins
Dynorphins
Interleukins
Flurazepam
Midazolam
Triazolam
Diazepam
Prolongation of sodium ion channel inactivation Mechanism of action Displacing NA of guanethidine as an (noradrenaline) antihypertensive from storage drug is by granules stoichiometricall y Which of the Amantadine following drugs is not useful for treatment of Parkinsonism Which of the Second following drugs are generation currently the tricyclic mainstay of antidepressents treatment of depressive psychosis Sulfinpyrazone is Anti used in treatment of inflammatory Gout because of activity Inverse agonist for Barbiturate benzodiazepine receptor is Histamine receptor H1 associated with acid secretion is Termination of Phenobarbitone action of which barbiturate is brought about by
Facilitation of GABA mediated chloride ion channel opening Inhibiting nerve impulse coupled release of NA
Benztropine
Bromocriptine
MAO inhibitors
Barbiturates
Phenothiazenes
Uricosuric action
Analgesic activity
Picrotoxin
Muscimol
H2
H3
Thiopentone
Secobarbitone
Pentobarbitone
13
redistribution Which of the following NSAID should not be used in patients with G-6- PD deficiency Buspirone is an Which of the following effects is not produced by ethyl alcohol The following drugs are avoided with warfarin The antidote for heparin is Agents/Drugs which help in rapid coagulation of Blood Warfarin therapy is prolonged by all except Heparin, apart from releasing lipoprotein lipase in the blood exerts its anti coagulant action by Which of the following statements is not correct regarding warfarin
Aspirin
Flurbiprofen
Diclofenac
Paracetamol
Antacids
Benzodiazepine
Penicillinase Astringents
Pryosulphate Haemostatics
Rifampicin
Amoxicillin
Erythromycin
Tetracycline
Binding to calcium
Percentage of total body iron distributed to myoglobin is The anticoagulant of choice during pregnancy is Clopidogrel is an
66 %
Better avoided during pregnancy as it may cause skeletal deformity of the foetus 25 %
In a racemic mixture the R from is four times more active than the S form 3%
6%
Warfarin sodium
Sodium oxalate
Heparin
Phenindone
A factor which a mucopolysaccaride, present in liver, participating in platelet aggregation is Oral iron formulation is Oral anticoagulant is
Antidiabetic drug
Antiplatelet drug
Acetylsalicylic acid
Heparin
14
Which of the following is produced by recombinant DNA technology for clinical use The dose of aspirin for inhibition of platelet aggregation is Vitamin K2 is specific antagonist for treatment of overdose of all except Parenteral iron therapy is used Which of the following is a specific chelator of iron Following drugs inhibit platelet aggregation except Which of the following agents increases oral iron absorption Iron preparation which can be administered by both I.M or I.V route is Which of the following fibrinolytics is not produced by recombinant DNA technology Menadione is a synthetic form of Drugs which reduce the action of oral anticoagulants are Ticlopidine is an
Vitamin B12
Erythropoietin
Vitamin B complex
75mg
600mg
1gm
4gms
Warfarin
Heparin
Dicoumarol
Phenindione
Desferrioxamine
Ticlopidine
Dipyridamole
Aspirin
Ascorbic acid
Tetracycline
Aluminium hydroxide
Iron dextran
Alteplase
Reteplase
Streptokinase
Tenecteplase
Which of the following is used in monitoring the dose of oral anticoagulants Which of the following is
Bleeding time
Clotting time
Cryoprecipitate
Platelet concentration
15
administered for urgent reversal of warfarin therapy BAL is Chelating agent used in arsenic poisoning is In a patient of megaloblastic anemia, the preferred line of therapy is Facial vein in digastric triangle lies Jugular venous arch is formed by Lymphatics of orbit train into Which of the following is assumed to have similar function as carotid body Epicranius consists of Bony labyrinth of internal ear consists of Submandibular gland is divided into 2 parts by Submandibular duct is wound around by Lateral surface of superficial part of submandibular salivary gland is related to the following except Secretomotor fibres to lacrimal gland pass through ______ nerve The smell of rancid butter is due to Multienzyme complex in humans is The rancidity of oils can be prevented by
Penicillamine Dimercaprol
Desferroxamine Desferrioxamine
Iron supplements
Superficial to mylohyoid Internal jugular veins Sub mandibular lymphnodes Tympanic body
Deep to mylohyoid External jugular veins Post auricular parotid lymphnodes Carotid sinus
Pierces mylohyoid Anterior jugular veins Pre auricular parotid lymphnodes Glomus jugulare
Occipitofrontalis Cochlea
Hyoglossus
Geniohyoid
Mylohyoid
Stylohyoid
Chordatympanic
Nervus intermedius
Auriculo temporal
16
Butter fat is unique in its content of Which ketone body does not possess a keto group The ketosis is due to absence of ________ enzyme in the liver The whole cholesterol molecule is completely synthesized from The rate limiting step in cholesterol biosynthesis is Hypercholesterolemi a is not found in Which of the following is not a disease of cholesterol deposition
Thiolase
Deacylase
Glycerol
Fatty acid
Glucose
Acetyl CoA
Mevalonate kinase
Hypothyroidism Atherosclerosis