BIMM 120 Winter 2009 TA: Abraham Tang

Section: Mondays 6PM; Thursdays 8AM abraham.h.tang@gmail.com

OH: by appointment

Week 1 material revisited

(bolded and underlined text indicates corrections or additional relevant
material not previously mentioned)
1. Outgrowth of Koch’s Discoveries
a. Criteria for establishing a causative link between an infectious
agent and a disease
b. Koch’s postulates
i. The microbe must be found in all cases of the disease, but
absent from healthy individuals
ii. The microbe must be isolated from the diseased host and
grown in pure culture
iii. The microbe must cause the same disease when
introduced into a healthy, susceptible host
iv. The same strain of microbe must be obtained from the
newly diseased host
2. Seminal events that launched the modern age (Page 12)
a. Be able to place these events in chronological order
3. Relevance of microbiology (Page 14)
4. Groups of microorganisms (Page 15)
a. Classify Prokaryotic and Eukaryotic
b. Viruses/ prions are also microbes? YES (for the purposes of this
class)
c. Can microbes can be seen with naked eye?
5. Relationship of microbes to other forms of life (Page 16)
a. Similarities
i. Metabolism
1. glycolysis
ii. Physical structure
1. What is the accepted model for both eukaryotic and
prokaryotic membranes and who created this
model?
2. Describe the fluid mosaic model.
b. Differences
i. Size
1. more complex tends to be larger (euk > prok)
ii. Cellular complexity
BIMM 120 Winter 2009 TA: Abraham Tang
Section: Mondays 6PM; Thursdays 8AM abraham.h.tang@gmail.com
OH: by appointment

1. cellular organization, organisms such as plants,

animals, insects, fungi, etc. are much more complex
than your typical bacterium (euk > prok)
iii. Metabolic diversity
1. prok > euk
6. Function of membrane enclosed systems (Page 17)
7. Presence or Absence of sterols * not in reader
a. Eukaryotes
i. present
b. Most prokaryotes
i. absent
c. Exceptions
i. Mycoplasma
ii. Methanotrophs
BIMM 120 Winter 2009 TA: Abraham Tang
Section: Mondays 6PM; Thursdays 8AM abraham.h.tang@gmail.com
OH: by appointment

Week 2 material
1. Define infection (Not in reader)
a. The growth of a ________ in or on a host
2. Ribosomal subunits (Page 18)
3. Significance of subunit type (Page 19)
a. What can cycloheximide be used for?
4. Peroxisome function (Not in text nor reader)
a. What can the peroxisome do?
b. What is the enzyme located in the peroxisome that is involved in
the function of the peroxisome?
5. Surface area to volume ratio (Not in reader)
a. Small cells: ________ SA/V ratio
i. (Greater/ Less) efficient trafficking
ii. Results in (faster/ slower) growth rate
b. Large cells: ________ SA/V ratio
i. (Greater/ Less) efficient trafficking
ii. Results in (faster/ slower) growth rate
6. Metabolic Diversity (Page 22)
a. Similarities
i.
ii.
b. Differences
i.
ii.
iii.
7. Cytoskeletal elements (Not in reader)
a. Microfilaments:
b. Intermediate filaments:
c. Microtubules:
d. Do both eukaryotes and prokaryotes have cytoskeletal elements?
8. Nuclear apparatus and sex (Page 23)
9. Arrangement of cocci (Page 30)
a. Staphylococcus vs Sarcinae
i. Staphylococcus:
ii. Sarcinae:
10. Morphological properties of bacteria (Page 27)
BIMM 120 Winter 2009 TA: Abraham Tang
Section: Mondays 6PM; Thursdays 8AM abraham.h.tang@gmail.com
OH: by appointment

a. ________, ________, ________

11. Comparison of gram positive and gram negative characteristics (Page
31)
12. Glycocalyx
a. Capsule vs slime layer (Page 34)
b. Composition of capsules and slime layers (Page 35)
c. Components (Pages 36-37)
d. Representative bacteria with capsule as major virulence factor
(Page 40)
e. S-layer (Page 41)
13. Flagella and pilli (Page 43)
14. Flagella arrangements (Page 47)
15. Principles of chemotaxis (Page 49)
a. Run with flagella rotating in ________ direction
b. Tumble with flagella rotating in ________ direction