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Kuan-Fu Chen CGMH EM

Rationale for R&D



Greater goal:

improve human life

Star Trek To boldly go where no man has gone before."

Higher cortical function Simply curious

Rationale for R&D


Practical consideration To get promoted in order to secure the
job

To better know the eld Responsibility to lead Capitalization of development/teaching/


research effort

Rationale of R&D & sub-specialty in EM


Pros:

To develop as a real specialty? Smith S. Is a career in emergency medicine associated with stigma? Eur J Emerg Med
2003;10:13-5.

To develop eld that no specialty cares? Formal EM subspecialties will play a limited role in the future of the specialty. Sinclair D. Subspecialization in emergency medicine: where do we go from here? CJEM. 2005 Sep;
7(5):344-6.

Cons:

Should we focus on building better environment/specialty rst?

Picking a Research Problem (Ten Commandments)



I. Anticipate the Results before Doing the First Study II. Pick an Area on Basis of Interest of Outcome III. Look for an Underoccupied Niche Has Potential IV. Go to Talks & Read Papers outside Area of Interest V. Build on a Theme

Picking a Research Problem (Ten Commandments)


VI. Find a Balance btw Low-Risk & High-Risk VII. Be Prepared to Pursue to Any Depth VIII. Differentiate Yourself from Your Mentor IX. Do not Assume Clinical Research Is
Easier

X. Focus, Focus, Focus

Mission
Establish infra-structure of research in
CGMH EM

Help faculty/subspecialty research


development

Methods
Basic research & EBM training Biweekly basic research training luncheon Biannual EBM workshop EBM tutorship Advanced research training (fellow research
training)

Year-long monthly training course

Methods

Research meeting

Biweekly meeting SAS workshop Retrospective cohort workshop Collaboration project with Foundation

Methodology workshop

Formal consultation

Methods
Current activities EBM Contest as a framework Shared interest as an interest group Curriculum for all sub-specialty fellows

Future direction

Methodology

Database management

Retrospective CGMH HIS query National health insurance research database


Conventional method: multivariate analysis Novel methods: propensity score, instrumental variable

Observational studies

Meta-analysis

Future direction
Clinical prediction rules (CPRs)/
Biosignature / Biomarker

Diagnostic medicine Clinical decision support system (CDSS) Clinical trials

Goal

Short-term:

Establish infra-structure via observational studies/ Meta-analysis Fulll requirement for attending physician in EM Building research theme for CGMH EM Collaboration with other specialty/institutes

Medium-term: Long-term:

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