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It goes beyond athletics; its life-long. Means of supplying oxygen. Fatigue is related % of maximal aerobic capacity of a particular workload. So, what does it have to do with us?
Consider what happens to you when you are sick/injured. The longer that the athlete is not working at his/her competitive level; the longer it takes to recover.
Controlled Setting Maximal Aerobic Capacity (VO2 Max) Metabolic Equivalents (METS) Practical Setting