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AG

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49 views76 pages

AG

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Cristina Elena Munteanu

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Acizi grasi

Digestia lipidelor

Bile salts emulsify dietary fats in the small intestine, forming mixed micelles. Intestinal lipases degrade triacylglycerols Chylomicron Fatty acids and other breakdown products are taken up by the intestinal mucosa and converted into triacylglycerols.

Structura unei lipoproteine Chilomicronul

Degradarea AG

Activarea AG

Activarea acizilor grasi

Transportul in mitocondrie

Transportul mitocondrial al AG

Oxidarea mitocondriala

Degradarea AG

Etapele oxidarii AG

Beta- oxidarea propriu zisa

Bilantul energetic al unui AG C18

Beta oxidarea AG in peroxizomi

Omega-oxidarea in RE

Degradarea AG nesaturati- ac.oleic

Deradarea AG cu nr.impar de atomi de carbon

Reglarea degradarii acizilor grasi

Corpii cetonici

Sinteza si degradarea corpilor cetonici

Reglarea cetogenezei

Sinteza AG
- Sinteza acidului palmitic (C16) de la acetilCoA

- Elongarea AG - Desaturarea AG

I. Sinteza C16: Transferul acetil-CoA din mitocondrie in citoplasma

I. Sinteza C16: sinteza malonil-CoA- etapa limitanta de viteza

I. Sinteza C16 - AGS

Elongarea AG

Desaturarea AG

Sinteza ac. arahidonic

Reglarea sintezei AG

Sinteza eicosanoizilor

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