DRUG NAME

INDICATION

FORMS

DOSAGE

MODE OF ACTION Anti-inflammatory effect; local administration into nasal passages maximizes beneficial effects on these tissues, while decreasing the likelihood of adverse effects from systemic absorption.

CONTRAINDI CATIONS Inhalation Contraindicate d with hypersensitivit y to drug or for relief of acute asthma or bronchospasm. Use cautiously with TB, systemic infections, lactation.

ADVERSE REACTIONS CNS: Headache, dizziness, lethargy , fatigue, paresthe sias, nervousness Dermatologic: R ash,edema, pruritu s, alopecia Endocrine: HPA suppression, Cushing's syndrome with overdosage a nd systemic absorption GI: Nausea, dyspepsia, dry mouth Local: Nasal irritation, fungal infection Respiratory: Epis taxis, rebound congestion, phary ngitis, cough Other: Chest pain, asthenia, moon face, acne, bruising, back pain

NURSING RESPONSIBILITI ES >WARNING: Tape r systemic steroids carefully during transfer to inhalational ster oids; deaths from adrenal insufficiency have occurred. >Arrange for use of decongestant nose drops to facilitate penetration if edema, excessive secretions are present. >Prime unit before use for Pulmicort Turbu haler; have patient rinse mouth after each use. > Use aerosol within 6 mo of opening. Shake well before each use. >Store Respules u pright and protected from light; gently shake before use; open envelopes should be discarded after 2 wk.

budesonide (bue des' oh ni de) Inhalation: Entocort (CAN ), Pulmicort Re spules, Pulmic ort Turbuhaler , Rhinocort Aq ua, Rhinocort Turbuhaler (C AN) DRUG CLASS: Corticosteroid

>Managemen t of symptoms of seasonal or perennial allergic rhinitis in adults and children; nonal lergic perennia l rhinitis in adults >Turbuhaler Maintenance treatment of asthma as prophylactic therapy in adults and children > 6 yr and for patients requiring corticosteroids for asthma Inhalation suspension > Maintenanc e treatment and prophylaxis therapy of asthma in children 12 mo8 yr

Aerosol32 mcg/actuatio n dry powder for inhalation 200 mcg (each actuation delivers 160 mcg) inhalation suspension 0.25 mg/2 mL , 0.5 mg/2 Ml capsules3 mg

Pulmicort Turbuhaler ADULTS Previously on inhaled corticosteroid s: Initially, 200400 mcg twice daily, maximum dose, 800 mcg bid (4 inhalations). Previously on bronchodilato rs alone: 200 400 mcg bid. Previously on oral corticosteroid s: 400800 m cg bid.