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    Propofol is a short-acting anesthetic used for induction and maintenance of general anesthesia. It works by rapidly redistributing from the brain to other tissues. Common adverse reactions include involuntary muscle movements, nausea, vomiting, headache, and fever. Nursing responsibilities include ensuring the patient is intubated and ventilated, closely monitoring vital signs, and discontinuing the infusion slowly to prevent agitation. Propofol must be administered carefully due to the risk of potentially fatal complications like apnea, bradycardia, and hypotension if not properly monitored.

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    9-Propofol

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    Propofol is a short-acting anesthetic used for induction and maintenance of general anesthesia. It works by rapidly redistributing from the brain to other tissues. Common adverse reactions include involuntary muscle movements, nausea, vomiting, headache, and fever. Nursing responsibilities include ensuring the patient is intubated and ventilated, closely monitoring vital signs, and discontinuing the infusion slowly to prevent agitation. Propofol must be administered carefully due to the risk of potentially fatal complications like apnea, bradycardia, and hypotension if not properly monitored.

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    5K views2 pages

    DRUG STUDY TITLE

    Uploaded by

    pretty_mary
    Propofol is a short-acting anesthetic used for induction and maintenance of general anesthesia. It works by rapidly redistributing from the brain to other tissues. Common adverse reactions include involuntary muscle movements, nausea, vomiting, headache, and fever. Nursing responsibilities include ensuring the patient is intubated and ventilated, closely monitoring vital signs, and discontinuing the infusion slowly to prevent agitation. Propofol must be administered carefully due to the risk of potentially fatal complications like apnea, bradycardia, and hypotension if not properly monitored.

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    of 2

    DRUG STUDY

    Prescribed and
    Generic Name Recommended
    Mechanism of Nursing
    Brand Name Dosage, Frequency, Indication Contraindication Adverse Reaction
    Action Responsibilities
    Classification and Route of
    Administration
    Propofol: Induction and Propofol is a short-  Induction and Electroconvul- Involuntary muscle 1. Patient must be
    acting anesthetic maintenance sive therapy, movements; nausea, Intubated and
    maintenance
     Diprifol amp obstetrics. vomiting, headache, ventilated
    given for induction of general
    emulsion injection of general anesthesia anesthesia Sedation in fever; pain, burning 2. Monitor: HR, ECG,
    Adult: Induction: 40 mg and maintenance of
     Diprivan amp children ≤16 yr. or stinging at Pulse Ox, BP
    general anesthesia.  Sedation 3. Abrupt
     Diprivan pre- by injection or infusion Pregnancy, injection site.
    Onset: 30 seconds. lactation. egg Potentially discontinuation of
    filled syringe every 10 seconds.
    Duration: 3-10 hypersensitivity, Fatal: Apnea, infusion may result in
     Fresofol 1% amp Usual dose: 1.5-2.5 minutes. soya lecithin bradycardia, rapid awakening with
     Hospira Propofol mg/kg. Maintenance: 4- Distribution: Extensi hypersensitivity; hypotension, agitation, anxiety
    vial 12 mg/kg/hr or use cautiously in convulsions; 4. Discard tubing/bottle
    vely redistributed from
    intermittent bolus hypotensive anaphylaxis after 12 hours
     IV-Pro solution brain to other tissues;
    injection of 20-50 mg.  patients 5. Do not use if
    for IV infusion crosses the placenta emulsion appears
     Lipuro amp Child: >8 yr: Induction and enters breast separated
     Lipuro IV- dose of 2.5 mg/kg. milk. Protein-binding: 6. Maintain strict aseptic
    infusion Maintenance dose: 9- 95% technique because
    15 mg/kg/hr by IV Metabolism: Extensiv emulsion will support
    rapid growth of
    infusion or intermittent ely hepatic; converted
    microorganisms.
    bolus injection.  to water-soluble 7. If hypotension or
    Elderly: Including sulfate and bradycardia occurs,
    neurosurgical and glucuronide decrease or stop
    debilitated patients: conjugates. Diprivan and monitor
    Infuse at a rate of 20 Excretion: Urine (as BP & HR, notifyMD
    metabolites); feces. 8. Document neuro
    mg every 10 seconds. assessment on
    Maintenance: 3-6 Elimination half-life:40
    awakening (Ramsey
    mg/kg/hr. Usual dose min (initial); 4-7 hr Level of Sedation
    Scale)
    DRUG STUDY

    Prescribed and
    Generic Name Recommended
    Mechanism of Nursing
    Brand Name Dosage, Frequency, Indication Contraindication Adverse Reaction
    Action Responsibilities
    Classification and route of
    Administration
    needed: 1-1.5 (terminal)
    mg/kg.Intravenous

    Sedation
    Adult: In diagnostic
    and surgical
    procedures: Initially, 6-
    9 mg/kg/hr by infusion
    given for 3-5 minutes or
    an alternative dose of
    0.5-1 mg/kg by slow
    injection over 1-5
    minutes.
    Maintenance: 1.5-4.5
    mg/kg/hr infusion.
    Reduce maintenance
    dose by 20% for high-
    risk patients needing
    sedation. For ventilated
    patients: 0.3-4 mg/kg/hr
    by infusion. Monitor
    lipid concentrations if
    duration of sedation
    lasts >3 days.

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