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ISMN

DRUG ORDER MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE EFECTS NURSING

ACTION CONSIDERATIONS

GENERIC NAME: Nitrates are drugs that act Prevention and treatment of The presence of any allergies Instruct patient to take
directly on the smooth muscle Angina Pectoris in Adults (CNS) Headache, dizziness,
to nitrates. These drugs are medication as
to cause relaxation and to also contraindicated in the and myasthenia. (GI) N & V directed, even if
ISOSORBIDE MONO depress muscle tone. following conditions: Severe and incontinence. ( CV) feeling better. Take
NITRATE (ISMN) anemia, head trauma or missed doses as soon
Hypotension. (SKIN) Flushintg
hemorrhage, pregnancy and as remembered; doses
BRAND NAME: lactation. pallor sweating and increased of isosorbide dinitrate
perspiration should be taken at
IMDUR 60mg least 2 hr apart (6 hr
with extended-release
preparations); daily
doses of isosorbide
CLASSIFICATION: mononitrate should be
 taken 7 hr apart. Do
ANTI-ANGINAL DRUGS not double doses. Do
not discontinue
abruptly
DOSAGE:

½ tab Caution patient to

make position
changes slowly to
ROUTE:
minimize orthostatic
PO hypotension

FREQUENCY:


OD
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AMLODIPINE

DRUG ORDER MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE EFECTS NURSING

ACTION CONSIDERATIONS

GENERIC NAME: Amlodipine is in a group of Amlodipine is used to treat Allergy to amlodipine, CNS: dizziness, light- Monitor BP for therapeutic
drugs called calcium channel high blood pressure impaired hepatic or renal headedness, headache,
blockers. Amlodipine relaxes (hypertension) or chest pain function, sick sinus asthenia (a condition marked effectiveness. BP reduction is
AMLODIPINE BESYLATE (widens) blood vessels and (angina) and other conditions syndrome, heart block by loss of strength in the
improves blood flow. caused by coronary artery (second or third degree), body), fatigue, lethargy greatest after peak levels of
BRAND NAME: disease lactation. Use cautiously with (tiredness, lack of energy).
CHF, pregnancy. CV: peripheral edema, amlodipine are achieved 6²9 h
NORVASC 5mg arrhythmias. Dermatologic:
flushing, rash. GI: nausea, following oral doses.
abdominal discomfort.

CLASSIFICATION:

ANTI-HYPERTENSIVE DRUGS
Monitor for S&S of dose-

related peripheral or facial

DOSAGE:
edema that may not be
1 tab
accompanied by weight gain;

ROUTE: rarely, severe edema may

cause discontinuation of drug.

PO

FREQUENCY:

OD
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CLOPIDOGREL

DRUG ORDER MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE EFECTS NURSING

ACTION CONSIDERATIONS
 
GENERIC NAME: Inhibits platelet aggregation Treatment of patients at risk Contraindicated with allergy P
geadache, dizziness, Assess for symptoms of
by blocking ADP receptors on for ischemic events³history to clopidogrel, active stroke, MI during treatment
weakness, syncope, flushing
platelets, preventing of MI, ischemic stroke, pathological bleeding such as
CLOPIDOGREL PHypertension, edema
clumping of platelets peripheral artery disease peptic ulcer or intracranial
BISULFATE c
 ‘ash, pruritus
 hemorrhage, lactation. Ê Nausea, GI distress,
 Monitor liver function studies:
constipation, diarrhea, GI
BRAND NAME: AST, ALT, bilirubin, creatinine
bleed
if patient is on long-term
"

Increased bleeding therapy
PLAVIX 25 mg risk

CLASSIFICATION: Monitor blood studies:

 CBC,Hgb, Hct, protime,
ANTI-PLATELET DRUG cholesterol if the patient is on
long-term therapy;
thrombocytopenia and
neutropenia may occur.
DOSAGE:

1 tab

ROUTE:

PO

FREQUENCY:

OD